Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells

Atherosclerosis

Volumn 214, Issue 2, 2011, Pages 350-356

  Bai, Qianming ^a,b   Xu, Leyuan ^a   Kakiyama, Genta ^a   Runge Morris, Melissa Ann ^c   Hylemon, Phillip B ^d   Yin, Lianhua ^b   Pandak, William M ^a   Ren, Shunlin ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FUDAN UNIVERSITY   (China)

^c WAYNE STATE UNIVERSITY   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

25 Hydroxycholesterol (25HC); 25 Hydroxycholesterol 3 sulfate (25HC3S); Cytosolic sulfotransferase (SULT2B1b); Lipid metabolism; Oxysterol sulfation

Indexed keywords

25 HYDROXYCHOLESTEROL; ABC TRANSPORTER A1; CHOLESTEROL; FAS ANTIGEN; FATTY ACID; MESSENGER RNA; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; OXYSTEROL; OXYSTEROL SULFOTRANSFERASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; SULFOTRANSFERASE; TRIACYLGLYCEROL; TRITIUM; UNCLASSIFIED DRUG;

ADENOVIRUS; AORTA; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE CONTROL; GENE OVEREXPRESSION; GENETIC CODE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMEOSTASIS; HUMAN; HUMAN CELL; LIPID METABOLISM; LIPID TRANSPORT; LIPOGENESIS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SULFATION;

CELLS, CULTURED; CHOLESTEROL ESTERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ENDOTHELIAL CELLS; FATTY ACIDS, NONESTERIFIED; GENE EXPRESSION REGULATION; HUMANS; HYDROCARBONS, FLUORINATED; HYDROXYCHOLESTEROLS; ORPHAN NUCLEAR RECEPTORS; RNA, MESSENGER; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; SULFONAMIDES; SULFOTRANSFERASES; TIME FACTORS; TRANSFECTION; TRIGLYCERIDES;

EID: 79151476474     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2010.11.021     Document Type: Article

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