Presenilin mouse and zebrafish models for dementia: Focus on neurogenesis

Progress in Neurobiology

Volumn 93, Issue 2, 2011, Pages 149-164

  van Tijn, Paula ^a,b   Kamphuis, Willem ^a   Marlatt, Michael W ^c   Hol, Elly M ^a   Lucassen, Paul J ^c  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Alzheimer's disease; Mouse model; Neurodegeneration; Neurogenesis; Presenilin; Zebrafish model

Indexed keywords

AMYLOID BETA PROTEIN; FLAVINE ADENINE NUCLEOTIDE; GAMMA SECRETASE INHIBITOR; PRESENILIN 1; PRESENILIN 2; SEMAGACESTAT; TAU PROTEIN; THY 1 ANTIGEN; WNT PROTEIN; ISOPROTEIN; PRESENILIN; SECRETASE;

ALZHEIMER DISEASE; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; DEMENTIA; DISEASE COURSE; EMBRYONIC STEM CELL; EXPERIMENTAL MODEL; GENE MUTATION; GENE TARGETING; GENETIC TRANSCRIPTION; GLIA; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL PLASTICITY; NERVE DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PHASE 3 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN POLYMORPHISM; REVIEW; SKIN CANCER; STEM CELL; SUBVENTRICULAR ZONE; VASCULAR DISEASE; ZEBRA FISH; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG ANTAGONISM; GENETICS; HUMAN; METABOLISM; MUTATION; PATHOPHYSIOLOGY; PHYSIOLOGY;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; DEMENTIA; DISEASE MODELS, ANIMAL; HUMANS; MICE; MUTATION; NEUROGENESIS; PRESENILINS; PROTEIN ISOFORMS; ZEBRAFISH;

EID: 78650591506     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2010.10.008     Document Type: Review

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