Alzheimer-associated C allele of the promoter polymorphism -22C>T causes a critical neuron-specific decrease of presenilin 1 expression

Human Molecular Genetics

Volumn 12, Issue 8, 2003, Pages 869-877

  Theuns, Jessie ^a   Remacle, Jacques ^a   Killick, Richard ^b   Corsmit, Ellen ^a   Vennekens, Krist'l ^a   Huylebroeck, Danny ^a   Cruts, Marc ^a   Van Broeckhoven, Christine ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; PRESENILIN 1;

ALLELE; ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BASE PAIRING; BINDING AFFINITY; BINDING SITE; CELL TYPE; CONTROLLED STUDY; GENE DELETION; GENE EXPRESSION; GENE MAPPING; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; RAT; REGULATORY MECHANISM; RISK ASSESSMENT;

ALLELES; ALZHEIMER DISEASE; ANIMALS; BASE SEQUENCE; CELLS, CULTURED; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NEURONS; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; POLYMORPHISM, GENETIC; PRESENILIN-1; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; REGULATORY SEQUENCES, NUCLEIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

ANIMALIA;

EID: 0242515917     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/ddg098     Document Type: Article

References (29)

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