Presenilin-1 regulates neuronal differentiation during neurogenesis

Development

Volumn 127, Issue 12, 2000, Pages 2593-2606

  Handler, Melissa ^a   Yang, Xudong ^a   Shen, Jie ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Alzheimer's disease; Brain; Cell fate determination; Dll1; Hes5; Notch1

Indexed keywords

LIGAND; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN VENTRICLE; CELL FATE; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; GENE MUTATION; HEMISPHERE; MESODERM; MOUSE; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; APOPTOSIS; BRAIN; CELL DIFFERENTIATION; CELL MOVEMENT; EMBRYONIC AND FETAL DEVELOPMENT; IN SITU HYBRIDIZATION; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEURONS; PRESENILIN-1; REFERENCE VALUES;

EID: 0033945494     PISSN: 09501991     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (58)

1. Akazawa, C., Sasai, Y., Nakanishi, S. and Kageyama, R. (1992). Molecular characterization of a rat negative regulator with a basic helix-loop-helix structure predominantly expressed in the developing nervous system. J Biol. Chem. 267, 21879-21885.
2. Artavanis-Tsakonas, S., Rand, M. D. and Lake, R. J. (1999). Notch signaling: cell fate control and signal integration in development. Science 284, 770-776.
3. Baumeister, R., Leimer, U., Zweckbronner, I., Jakubek, C., Grunberg, J. and Haass, C. (1997). Human presenilin-1, but not familial Alzheimer's disease (FAD) mutants, facilitate Caenorhabditis elegans Notch signalling independently of proteolytic processing. Genes Funct. 2, 149-159.
4. Bettenhausen, B., de Angelis, M., Simon, D., Guenet, J. and Gossler, A. (1995). Transient and restricted expression during mouse embryogenesis of DII1, a murine gene closely related to Drosophila Delta. Development 121, 2407-2418.
5. Chae, T., Kwon, Y., Bronson, R., Dikkes, P., Li, E. and Tsai, L.-H. (1997). Mice lacking p35, a neuronal specific activator of cdk5, display cortical lamination detects, seizures, and adult lethality. Neuron 18, 29-42.
6. Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D. and Kintner, C. (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delia. Nature 375, 761-766.
7. Conlon, R. A., Reaume, A. G. and Rossant, J. (1995). Notch I is required for the coordinate segmentation of somites. Development 121, 1533-1545.
8. Crandall, J. E., Jacobson, M. and Kosik, K. S. (1986). Ontogenesis of microtubule-associated protein 2 (MAP2) in embryonic mouse cortex. Brain Res. 393, 127-133.
9. de la Pompa, J. L., Wakeham, A., Correia, K. M., Samper, E., Brown, S., Aguilera, R. J., Nakano, T., Honjo, T., Mak, T. W., Rossant, J. and Conlon, R. A. (1997). Conservation of the Notch signalling pathway in mammalian neurogenesis. Development 124, 1139-1148.
10. De Strooper, B., Annaert, W., Cupers, P., Saftig, P., Craessaerts, K., Mumm, J. S., Schroeter, E. H., Schrijvers, V., Wolfe, M. S., Ray, W. J., Goate, A. and Kopan, R. (1999). A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain [see comments]. Nature 398, 518-522.
11. Deckwerth, T. and Johnson, E. (1993). Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor. J. Cell Biol. 123, 1207-22.
12. Deng, G., Pike, C. J. and Cotman, C. W. (1996). Alzheimer-associated presenilin-2 confers increased sensitivity to apoptosis in PC12 cells. FEBS Lett. 39979, 50-54.
13. Franco Del Amo, F., Smith, D., Swiatek, P., Gendron-maguire, M., Greenspan, R., McMahon, A. and Gridley, T. (1992). Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development 115, 737-744.
14. Gavrieli, Y., Sherman, Y. and Ben-Sasson, S. (1992). Identification of programmed cell death in sutu via specific labelling of nuclear DNA fragmentation. J. Cell Biol. 119, 493-501.
15. Giniger, E. (1988). A role for Abl in Notch signalling. Neuron 20, 667-81.
16. Gratzner, H. G. (1982). Monoclonal antibody to 5-bromo- and 5-iododeoxyuridine: A new reagent for detection of DNA replication. Science 218, 474-475.
17. Guo, Q., Furukawa, K., Sopher, B., Pham, D., Xie, J., Robinson, N., Nartin, G. and Mattson, M. (1996). Alzheimer's PSI mutation perturbs calcium homeostasis and sensitizes PC-12 cells to death induced by amyloid β-peptide. Neurorep. 8, 379-383.
18. Hamada, Y., Kadokawa, Y., Okabe, M., Ikawa, M., Coleman, J. and Tsujimoto, Y. (1999). Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality. Development 126, 3415-3424.
19. Hartmann, D., De Strooper, B. and Saftig, P. (1999). Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly. Curr. Biol. 9, 719-727.
20. Heitzler, P., Bourouis, M., Ruel, L., Carteret, C. and Simpson, P. (1996). Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development 122, 161-171.
21. Heitzler, P. and Simpson, P. (1993). Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. Development 117, 1113-1123.
22. Heitzler, P. and Simpson, P. (1991). The choice of cell fate in the epidermis of Drosophila. Cell 64, 1083-1092.
23. Henrique, D., Adam, J., Myat, A., Chitnis, A., Lewis, J. and Ish-Horowicz, D. (1995). Expression of a Delta homologue in prospective neurons in the chick. Nature 375, 787-790.
24. Hogan, B., Beddington, R., Constantini, F. and Lacy, E. (1994). Manipulating The Mouse Embryo: A Laboratory Manual, 2nd Edition. Cold Spring Harbor Laboratory Press, NY.
25. Howell, B., Hawkes, R., Soriano, P. and Cooper, J. (1997). Neuronal position in the developing brain is regulated by mouse disabled-1. Nature 389, 733-737.
26. Ishibasbi, M., Ang, S. L., Shiota, K., Nakanishi, S., Kageyama, R. and Guillemot, F. (1995). Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulalion of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 9, 3136-1348.
27. Ishibashi, M., Moriyoshi, K., Sasai, Y., Shiota, K., Nakanishi, S. and Kageyama, R. (1994). Persistent expression of helix-loop-helix factor HES-1 prevents mammalian neural differentiation in the central nervous system. EMBO J. 13, 1799-1805.
28. Johansson, C. B., Momma, S., Clarke, K. L., Risling, M., Lendahl, U. and Frisen, J. (1999). Identification of a neural stem cell in the adult mammalian central nervous system. Cell 96, 25-34.
29. Kageyama, R. and Nakanishi, S. (1997). Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. Curr. Opin. Genet. Dev. 7, 659-665.
30. Kim, J., Sebring, A., Esch, J., Kraus, M., Vorwerk, K., Magee, J. and Carroll, S. (1996), Integration of positional signals and regulation of wing formation and identity by Drosophilu vestigial gene. Nature 382, 133-138.
31. Kim, T., Pettingell, W., Jung, Y., Kovacs, D. and Tanzi, R. (1997). Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a Caspase-3 family protease. Science 277, 373-376.
32. Levitan, D., Doyle, T. G., Brousseau, D., Lee, M. K., Thinakaran, G., Slunt, H. H., Sisodia, S. S. and Greenwald, I. (1996). Assessment of normal and mutant human presenilin function in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 93, 14940-14944.
33. Levitan, D. and Greenwald, I. (1998). Effects of SEL-12 presenilin on LIN-12 localization and function in Caenorhabditis elegans. Development 125, 3599-3506.
34. Levitan, D. and Greenwald, I. (1995). Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis eleganns S182 Alzheimer's disease gene. Nature 377, 351-354.
35. Loetscher, H., Deuschle, U., Brockhaus, M., Reinhardt, D., Nelboeck, P., Mous, J., Grunberg, J., Haass, C. and Jacobsen, H. (1997) Presenilins are processed by caspase-type proteases. J. Biol. Chem. 272, 20655-20659.
36. Logeat, F., Bessia, C., Brou, C., LeBail, O., Jarriault, S., Seidah, N. and Israel, A. (1998). The Notchl receptor is cleaved constitutively by a furin-like convertase. Proc. Natl. Acad Sci. USA 95, 8108.
37. McConnell, S. K. (1995). Constructing the cerebral cortex: neurogenesis and fate determination. Neuron 15, 761-768.
38. Ohshima, T., Ward, J., Huh, C-G., Longenecker, G., Veeranna, Pant, H., Brady, R., Martin, L. and Kulkarni, A. (1996). Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death. Proc. Natl. Acad. Sci. USA 93, 11173-11178.
39. Ohtsuka, T., Ishibashi, M., Gradwohl, G., Nakanishi, S., Guillemot, F. and Kageyama, R. (1999). Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J. 18, 2196-2207.
40. Reaume, A., Conlon, R., Zirngibl, R., Yamaguchi, T. and Rossant, J. (1992). Expression analysis of a Notch homologue in the mouse embryo. Dev. Biol. 154, 377-387.
41. Roperch, J. P., Alvaro, V., Prieur, S., Tuynder, M., Nemani, M., Lethrosne, F., Piouffre, L., Gendron, M. C., Israeli, D., Dausset, J., Oren, M., Amson, R. and Telerman, A. (1998). Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression [In Process Citation]. Nat. Med. 4, 835-838.
42. Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R. and Nakanishi, S. (1992). Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6, 2620-2634.
43. Schaeren-Wiemers, N. and Gerfin-Moser, A. (1993) A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100, 431-440.
44. Selkoe, D. J. (1998). The cell biology of ß-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol. 8, 447-453.
45. Shen, J., Bronson, R. T., F, C. D., Xia, W., Selkoe, D. J. and Tonegawa, S. (1997). Skeletal and CNS defects in presnilin-1 deficient mice. Cell 89, 629-639.
46. Song, W., Nadeau, P., Yuan, M., Yang, X., Shen, J. and Yankner, B. A. (1999). Proteolytic release and nuclear translocation of notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations. Proc. Natl. Acad. Sci. USA 96, 6959-6963.
47. Struhl, G. and Greenwald, I. (1999). Presenilin is required for activity and nuclear access of Notch in Drosophila [see comments]. Nature 398, 522-525.
48. Swiatek, P. J., Lindsell, C. E., Franco del Amo, F., Weinmaster, G. and Gridley, T. (1994). Notch I is essential for postimplantation development in mice. Genes Dev. 8, 707-719.
49. Takahashi, T., Nowakowski, R. S. and Caviness, V. S., Jr. (1995). The cell cycle of the pseudostratified ventricular epithelium of the embryonic murine cerebral wall. J. Neurosci. 15, 6046-6057.
50. Takebayashi, K., Akazawa, C., Nakanishi, S. and Kageyama, R. (1995). Structure and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-5 Identification of the neural precursor cell-specific promoter element. J. Biol. Chem. 270, 1342-1349.
51. Tomita, K., Ishibashi, M., Nakahara, K., Ang, S., Nakanishi, S. and Kageyama, R. (1996). Mammalian hairy and Enhancer of split homolog 1 regulates differentiation of retinal neurons and is essential for eye morphogenesis. Neuron 16, 723-734.
52. Van Doren, M., Powell, P. A., Pasternak, D., Singson, A. and Posakony, J. W. (1992). Spatial regulation of proneural gene activity: auto- and cross-activation of achaete is antagonized by extramacrochaetae. Genes Dev. 6, 2592-2605.
53. 2+ Binding protein ALG-2 and Alzhermer's disease gene ALG-3. Science 271, 521-525.
54. Wolozin, B., Iwasaki, K., Vito, P., Ganjei, K., Lacana, E., Sunderland, T., Zhao, B., W, K. J., Wasco, W. and D'Adamio, L. (1996). PS2 participates in cellular apoptosis: Constitutive activity conferred by Alzheimer mutation. Science 274, 1710-1713.
55. Wong, P., Zhen, H., Chen, H., Becher, M. W., Sirinathsinghji, D. J., Trumbauer, M. E., Proce, D. L., Van der Ploeg, L. H. T. and Sisodia, S. S. (1997). Presenilin I is required for Notch 1 and D111 expression in the paraxial mesoderm. Nature 397, 288.
56. Ye, Y. and Fortini, M. (1999). Apoptotic activities of wild-type and Alzheimer's disease-related mutant presenilins in Drosophila melangaster. J. Cell Biol. 146, 1351-1364.
57. Ye, Y., Lukinova, N. and Fortini, M. E. (1999). Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature 398, 525-529.
58. Zhang, Z., Hartmann, H., Do, V. M., Abramowski, D., Sturchler-Pierrat, C., Staufenbiel, M., Sommer, B., va de Wetering, M., Clevers, H., Saftig, P., De Strooper, B., He, X. and Yankner, B. (1998). Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 395, 698-702.