Loss-of-function presenilin mutations in Alzheimer disease. Talking Point on the role of presenilin mutations in Alzheimer disease

EMBO Reports

Volumn 8, Issue 2, 2007, Pages 141-146

  De Strooper, Bart ^a  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; ANTERIOR PHARYNX DEFECTIVE 1 PROTEIN; BETA CATENIN; BRAIN PROTEIN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; NERVE CELL ADHESION MOLECULE; NICASTRIN; NONSTEROID ANTIINFLAMMATORY AGENT; NOTCH RECEPTOR; PRESENILIN; PRESENILIN 1; PRESENILIN 2; PROGRANULIN; SYNDECAN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMYLOIDOSIS; APOPTOSIS; AUTOPHAGY; BIOCHEMISTRY; CALCIUM HOMEOSTASIS; CARBOXY TERMINAL SEQUENCE; DEGENERATIVE DISEASE; DRUG TARGETING; ENZYME ACTIVITY; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; HUMAN; MEMORY DISORDER; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; HUMANS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDE FRAGMENTS; PRESENILINS; PROTEIN CONFORMATION;

EID: 33947201115     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400897     Document Type: Review

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