Activation of the Notch pathway in Down syndrome: Cross-talk of Notch and APP

FASEB Journal

Volumn 19, Issue 11, 2005, Pages 1451-1458

  Fischer, David F ^a,b   Van Dijk, Renske ^a   Sluijs, Jacqueline A ^a   Nair, Suresh M ^a   Racchi, Marco ^c   Levelt, Christiaan N ^a   Van Leeuwen, Fred W ^a   Hol, Elly M ^a  

^a NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

APP; secretase complex; Alzheimer disease; Notch intracellular domain

Indexed keywords

AMYLOID PRECURSOR PROTEIN; DELTA LIKE PROTEIN 1; GAMMA SECRETASE; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEIN; TRANSCRIPTION FACTOR HES 1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; BRAIN DEVELOPMENT; CELL DIFFERENTIATION; DOWN SYNDROME; FIBROBLAST; GENE OVEREXPRESSION; GLIA CELL; HUMAN; HUMAN CELL; MENTAL DEFICIENCY; MOLECULAR INTERACTION; NERVE CELL; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRISOMY 21;

ADULT; AGED; AMYLOID BETA-PROTEIN PRECURSOR; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELLS, CULTURED; CEREBRAL CORTEX; DOWN SYNDROME; HOMEODOMAIN PROTEINS; HUMANS; MIDDLE AGED; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANS-ACTIVATION (GENETICS);

EID: 24644451508     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.04-3395.com     Document Type: Article

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