The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice

Experimental Neurology

Volumn 188, Issue 2, 2004, Pages 224-237

  Wen, Paul H ^a,b   Hof, Patrick R ^a   Chen, Xiaoping ^a   Gluck, Karen ^a   Austin, Gregory ^b   Younkin, Steven G ^c   Younkin, Linda H ^c   DeGasperi, Rita ^a,b   Gama Sosa, Miguel A ^a,b   Robakis, Nikolaos K ^a   Haroutunian, Vahram ^a,b   Elder, Gregory A ^a,b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Bromodeoxyuridine; Familial Alzheimer disease; Presenilin 1

Indexed keywords

BETA TUBULIN; BROXURIDINE; NEURON SPECIFIC ENOLASE; PRESENILIN 1;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL LABELING; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; HIPPOCAMPUS; IMMUNOCOMPETENT CELL; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; STRAIN DIFFERENCE; TRANSGENIC MOUSE; WILD TYPE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PROTEIN; ANIMALS; ANTIGENS, DIFFERENTIATION; BROMODEOXYURIDINE; CELL COUNT; CELL SURVIVAL; DISEASE MODELS, ANIMAL; ENVIRONMENT; GENE EXPRESSION; HIPPOCAMPUS; HUMANS; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; NEURONS; PEPTIDE FRAGMENTS; PRESENILIN-1; STEM CELLS;

EID: 3042751874     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2004.04.002     Document Type: Article

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