Differential processing of amyloid-β precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells

Journal of Biological Chemistry

Volumn 284, Issue 35, 2009, Pages 23806-23817

  Porayette, Prashob ^a   Gallego, Miguel J ^a   Kaltcheva, Maria M ^a   Bowen, Richard L ^b   Meethal, Sivan Vadakkadath ^a   Atwood, Craig S ^a,c,d  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b OTB Research   (United States)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d EDITH COWAN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; AMYLOID PLAQUES; CLEAVAGE PRODUCTS; DOWN SYNDROME; HEAD INJURIES; HUMAN EMBRYONIC STEM CELLS; NEURAL PRECURSORS; NEURODEGENERATIVE; NEUROGENESIS; NEURONAL PRECURSOR CELLS; PRECURSOR PROTEINS; SECRETASES; TRANS-MEMBRANE PROTEINS;

CELL GROWTH; CELL MEMBRANES; CELL PROLIFERATION; PLASTIC PRODUCTS; PUMPING PLANTS;

GLYCOPROTEINS;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; NESTIN; SECRETASE;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; EMBRYONIC STEM CELLS; HUMANS; NEURONS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

EID: 69949132002     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.026328     Document Type: Article

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