Expression of presenilin-1 and -2 mRNAs in rat and Alzheimer's disease brains

Brain Research

Volumn 748, Issue 1-2, 1997, Pages 122-130

  Takami, Kenji ^a,b   Terai, Kazuhiro ^b   Matsuo, Akinori ^b   Walker, Douglas G ^b   McGeer, Patrick L ^b  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Alzheimer's disease; in situ hybridization; presenilin 1; presenilin 2; rat

Indexed keywords

PRESENILIN 1; PRESENILIN 2;

AGED; ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CASE REPORT; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALZHEIMER DISEASE; ANIMALS; BRAIN; HUMANS; IN SITU HYBRIDIZATION; MALE; MEMBRANE PROTEINS; PRESENILIN-1; PRESENILIN-2; RATS; RATS, WISTAR; REFERENCE VALUES; RNA, MESSENGER;

EID: 0031044834     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(96)01274-7     Document Type: Article

References (24)

1. Altschul, S.F., Gish, W., Miller, W., Myers, E.W. and Lipman, D.J., Basic local alignment search tool, J. Mol. Biol., 215 (1990) 403-410.
2. Anonymous, The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families. Alzheimer's Diseasse Collaborative Group, Nature Genetics, 11 (1995) 219-222.
3. Anwar, R., Moynihan, T.P., Ardley, H., Brindle, N., Coletta, P.L., Cairns, N., Markham, A.F. and Robinson, P.A., Molecular analysis of the presenilin 1 (S182) gene in sporadic cases of Alzheimer's disease - identification and characterisation of unusual splice variants, J. Neurochem., 66 (1996) 1774-1777.
4. Campion, D., Flaman, J.M., Brice, A., Hannequin, D., Dubois, B., Martin, C., Moreau, V., Charbonnier, F., Didierjean, O., Tardieu, S., Penet, C., Fuel, M., Pasquier, F., Ledoze, F., Bellis, G., Calenda, A., Heilig, R., Martinez, M., Mallet, J., Bellis, M., Clergetdarpoux, F., Agid, Y. and Frebourg, T., Mutations of the presenilin 1 gene in families with early-onset Alzheimer's disease, Hum. Mol. Genetics, 4 (1995) 2373-2377.
5. Cruts, M., Backhovens, H., Wang, S.Y., Vangassen, G., Theuns, J., Dejonghe, C., Wehnert, A., Devoecht, J., Dewinter, G., Cras, P., Bruyland, M., Datson, N., Weissenbach, J., Dendunnen, J.T., Martin, J.J., Hendriks, L. and Vanbroeckhoven, C., Molecular genetic analysis of familial early-onset Alzheimers disease linked to chromosome 14q24.3, Hum. Mol.Genetics, 4 (1995) 2363-2371.
6. Dionne, C.A., Crumley, G., Bellot, F., Kaplow, J.M., Searfoss, G., Ruta, M., Burgess, W.H., Jaye, M. and Schlessinger, J., Cloning and expression of two distinct high-affinity receptors cross-reacting with acidic and basic fibroblast growth factors, EMBO J., 9 (1990) 2685-2692.
7. Khachaturian, Z.S., Diagnosis of Alzheimer's disease, Arch. Neurol., 42 (1985) 1097-1105.
8. Kovacs, D.M., Fausett, H.J., Page, K.J., Kim, T.W., Moir, R.D., Merriam, D.E., Hollister, R.D., Hallmark, O.G., Mancini, R., Felsenstein, K.M., Hyman, B.T., Tanzi, R.E. and Wasco, W., Alzheimer-associated presenilins 1 and 2 - neuronal expression in brain and localization to intracellular membranes in mammalian cells, Nature Med., 2 (1996) 224-229.
9. Levitan, D. and Greenwald, I., Facilitation of lin-12-mediated signalling by sel-12, a caenorhabditis elegans S182 Alzheimer's disease gene, Nature, 377 (1995) 351-354.
10. Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D.M., Oshima, J., Pettingell, W.H., Yu, C.E., Jondro, P.D., Schmidt, S.D., Wang, K., Crowley, A.C., Fu, Y.H., Guenette, S.Y., Galas, D., Nemens, E., Wijsman, E.M., Bird, T.D., Schellenberg, G.D. and Tanzi, R.E., Candidate gene for the chromosome 1 familial Alzheimer's disease locus, Science, 269 (1995) 973-977.
11. Martins, R.H., Turner, B.A., Carroll, R.T., Sweeney, D., Kim, K.S., Wisniewski, H.M., Blass, J.P., Gibson, G.E. and Gandy, S., High levels of amyloid-beta protein from S182 (glu(246)) familial Alzheimer's cells, Neuroreport, 7 (1995) 217-220.
12. McGeer, P.L. and McGeer, E.G., The inflammatory response system of brain, implications for therapy of Alzheimer and other neurodegenrative diseases, Brain Res. Rev., 21 (1995) 195-218.
13. Moussaoui, S., Czech, C., Pradier, L., Blanchard, V., Bonici, B., Gohin, M., Imperato, A. and Revah, F., Immunohistochemical analysis of presenilin-1 expression in the mouse brain, FEBS Lett., 383 (1996) 219-222.
14. Rogaev, E.I., Sherrington, R., Rogaev, E.A., Levesque, G., Ikeda, M., Liang, Y., Chi, H., Holman, K. and Tsuda, T., Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene, Nature, 376 (1995) 775-778.
15. Sherrington, R., Rogaev, E.I., Liang, Y., Rogaev, E.A., Levesque, G., Ikeda, M., Chi, H., Li, G. and Holman, K., Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease, Nature, 375 (1995) 754-760.
16. Sorbi, S., Nacmias, B., Forleo, P., Piacentini, S., Sherrington, R., Rogaev, E., Hyslop, P. and Amaducci, L., Missense mutation of S182 gene in italian families with early-onset Alzheimer's disease, Lancet, 346 (1995) 439-440.
17. Suzuki, T., Nishiyama, K., Murayama, S., Yamamoto, A., Sato, S., Kanazawa, I. and Sakaki, Y., Regional and cellular presenilin 1 gene expression in human and rat tissues, Biochem. Biophys. Res. Commun., 219 (1996) 708-713.
18. Takami, K., Iwane, M., Kiyota, Y., Miyamoto, M., Tsukuda, R. and Shiosaka, S., Increase of basic fibroblast growth factor immunoreactivity and its mRNA level in rat brain following transient forebrain ischemia, Exp. Brain Res., 90 (1992) 1-10.
19. Tanahashi, H., Mitsunaga, Y., Takahashi, K., Tasaki, H., Watanabe, S. and Tabira, T., Missense mutation of S182 gene in Japanese familial Alzheimer's disease, Lancet, 346 (1995) 440.
20. Tsuda, T., Chi, H., Liang, Y., Rogaeva, E.A., Sherrington, R., Levesque, G., Ikeda, M., Rogaev, E.I., Pollen, D., Freedman, M., Duara, R. and Stgeorgehyslop, P.H., Failure to detect missense mutations in the S182 gene in a series of late-onset Alzheimer's disease cases, Neurosci. Lett., 201(1995) 188-190.
21. Vito, P., Lacana, E. and Dadamio, L., Interfering with apoptosis -Ca2 + -binding protein ALG-2 and Alzheimer's disease gene ALG-3, Science, 271 (1996) 521-525.
22. Wasco, W., Pettingell, W.P., Jondro, P.D., Schmidt, S.D., Gurubhagavatula, S., Rodes, L., DiBlasi, T., Romano, D.M., Guenette, S.Y., Kovacs, D.M., Growdon, J.H. and Tanzi, R.E., Familial Alzheimer's chromosome 14 mutations, Nature Med., 1 (1995) 848.
23. Wisniewski, T., Palha, J.A., Ghiso, J. and Frangione, B., S182 protein in Alzheimer's disease neuritic plaques, Lancet, 346 (1995) 1366.
24. Young, W.S.I., Bonner, T.I. and Brann, M.R., Mesencephalic dopaminergic neurons regulate the expression of neuropeptide mR-NAs in the rat forebrain, Proc. Natl. Acad. Sci. USA, 83 (1986) 9827-9831.