Accumulation of murine amyloidβ42 in a gene-dosage-dependent manner in PS1 'knock-in' mice

European Journal of Neuroscience

Volumn 11, Issue 7, 1999, Pages 2577-2581

  Nakano, Y ^a   Kondoh, G ^a   Kudo, T ^a   Imaizumi, K ^a   Kato, M ^a   Miyazaki, J I ^a   Tohyama, M ^a   Takeda, J ^a   Takeda, M ^a  

^a OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Alzheimer's disease; Amyloid precursor protein; Cre loxP; Missense mutation

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); MEMBRANE PROTEIN; PEPTIDE FRAGMENT; PRESENILIN 1;

ALLELE; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; FEMALE; FETUS; GENE DOSAGE; GENE LOCUS; MALE; MISSENSE MUTATION; MOUSE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ANIMAL; BRAIN; CELL CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSCRIPTION; GENETICS; HETEROZYGOTE; HOMOZYGOTE; METABOLISM; MOUSE STRAIN; NERVE CELL; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

ALLELES; AMYLOID BETA-PROTEIN; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; BRAIN; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE DOSAGE; GENE EXPRESSION; HETEROZYGOTE; HOMOZYGOTE; MEMBRANE PROTEINS; MICE; MICE, INBRED STRAINS; MUTATION, MISSENSE; NEURONS; PEPTIDE FRAGMENTS; PRESENILIN-1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 0032588722     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.1999.00698.x     Document Type: Article

References (16)