-
1
-
-
34447299235
-
Orthomyxoviridae: The viruses and their replication
-
Knipe DM, Howley PM (Eds). Lippincott Williams & Wilkins, PA, USA
-
Palese P, Shaw ML: Orthomyxoviridae: the viruses and their replication. In: Fields Virology. Knipe DM, Howley PM (Eds). Lippincott Williams & Wilkins, PA, USA, 1647-1689 (2007).
-
(2007)
Fields Virology
, pp. 1647-1689
-
-
Palese, P.1
Shaw, M.L.2
-
4
-
-
0001178031
-
Orthomyxoviruses
-
Knipe DM, Howley PM (Eds). Lippincott Williams & Wilkins, PA, USA
-
Wright PF, Webster RG: Orthomyxoviruses. In: Fields Virology. Knipe DM, Howley PM (Eds). Lippincott Williams & Wilkins, PA, USA, 1533-1579 (2007).
-
(2007)
Fields Virology
, pp. 1533-1579
-
-
Wright, P.F.1
Webster, R.G.2
-
5
-
-
67650680609
-
Influenza virus A (H1N1) in giant anteaters (Myrmecophaga tridactyla)
-
Nofs S, Abd-Eldaim M, Thomas KV, Toplon D, Rouse D, Kennedy M: Influenza virus A (H1N1) in giant anteaters (Myrmecophaga tridactyla). Emerg. Infect. Dis. 15, 1081-1083 (2009).
-
(2009)
Emerg. Infect. Dis.
, vol.15
, pp. 1081-1083
-
-
Nofs, S.1
Abd-Eldaim, M.2
Thomas, K.V.3
Toplon, D.4
Rouse, D.5
Kennedy, M.6
-
6
-
-
36049022594
-
Influenza virus transmission is dependent on relative humidity and temperature
-
Lowen AC, Mubareka S, Steel J, Palese P: Influenza virus transmission is dependent on relative humidity and temperature. PLoS Pathog. 3, 1470-1476 (2007).
-
(2007)
PLoS Pathog.
, vol.3
, pp. 1470-1476
-
-
Lowen, A.C.1
Mubareka, S.2
Steel, J.3
Palese, P.4
-
7
-
-
41049107320
-
Epidemiology and control of human and animal influenza
-
Kawaoka Y (Ed.). Caister Academic Press, Norwich, UK
-
Subbarao K, Swayne DE, Olsen CW: Epidemiology and control of human and animal influenza. In: Influenza Virology: Current Topics. Kawaoka Y (Ed.). Caister Academic Press, Norwich, UK, 229-280 (2006).
-
(2006)
Influenza Virology: Current Topics
, pp. 229-280
-
-
Subbarao, K.1
Swayne, D.E.2
Olsen, C.W.3
-
8
-
-
50549100621
-
The origin and virulence of the 1918 'Spanish' influenza virus
-
Kawaoka Y (Ed.). Caister Academic Press, Norwich, UK
-
Taubenberger JK, Palese P: The origin and virulence of the 1918 'Spanish' influenza virus. In: Influenza Virology: Current Topics. Kawaoka Y (Ed.). Caister Academic Press, Norwich, UK, 299-322 (2006).
-
(2006)
Influenza Virology: Current Topics
, pp. 299-322
-
-
Taubenberger, J.K.1
Palese, P.2
-
10
-
-
36148966751
-
H5 influenza viruses
-
Kawaoka Y (Ed.). Caister Academic Press, Norwich, UK
-
Webster RG: H5 influenza viruses. In: Influenza Virology: Current Topics. Kawaoka Y (Ed.). Caister Academic Press, Norwich, UK, 281-298 (2006).
-
(2006)
Influenza Virology: Current Topics
, pp. 281-298
-
-
Webster, R.G.1
-
11
-
-
67649297821
-
Emergence and pandemic potential of swine-origin H1N1 influenza virus
-
Neumann G, Noda T, Kawaoka Y: Emergence and pandemic potential of swine-origin H1N1 influenza virus. Nature 459, 931-939 (2009).
-
(2009)
Nature
, vol.459
, pp. 931-939
-
-
Neumann, G.1
Noda, T.2
Kawaoka, Y.3
-
12
-
-
67649538978
-
Origins and evolutionary genomics of the 2009. swine-origin H1N1 influenza A epidemic
-
Smith GJ, Vijaykrishna D, Bahl J et al.: Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic. Nature 459, 1122-1125 (2009).
-
(2009)
Nature
, vol.459
, pp. 1122-1125
-
-
Smith, G.J.1
Vijaykrishna, D.2
Bahl, J.3
-
13
-
-
36348940608
-
Interferons and viruses: An interplay between induction, signalling, antiviral responses and virus countermeasures
-
Randall RE, Goodbourn S: Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures. J. Gen. Virol. 89, 1-47 (2008).
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 1-47
-
-
Randall, R.E.1
Goodbourn, S.2
-
14
-
-
37549001315
-
The influenza virus NS1 protein: Inhibitor of innate and adaptive immunity
-
Fernandez-Sesm A: The influenza virus NS1 protein: inhibitor of innate and adaptive immunity. Infect. Disord. Drug Targets 7, 336-343 (2007).
-
(2007)
Infect. Disord. Drug Targets
, vol.7
, pp. 336-343
-
-
Fernandez-Sesm, A.1
-
15
-
-
33745242372
-
Influenza virus evades innate and adaptive immunity via the NS1 protein
-
Fernandez-Sesma A, Marukian S, Ebersole BJ et al.: Influenza virus evades innate and adaptive immunity via the NS1 protein. J. Virol. 80, 6295-6304 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 6295-6304
-
-
Fernandez-Sesma, A.1
Marukian, S.2
Ebersole, B.J.3
-
16
-
-
67449097020
-
The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells
-
Haye K, Burmakina S, Moran T, Garcia Sastre A, Fernandez-Sesma A: The NS1 protein of a human influenza virus inhibits type I interferon production and the induction of antiviral responses in primary human dendritic and respiratory epithelial cells. J. Virol. 83, 6849-6862 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 6849-6862
-
-
Haye, K.1
Burmakina, S.2
Moran, T.3
Garcia Sastre, A.4
Fernandez-Sesma, A.5
-
17
-
-
0034003375
-
The role of a/b and g interferons in development of immunity to influenza A virus in mice
-
Price GE, Gaszewska-Mastarlarz A, Moskophidis D: The role of a/b and g interferons in development of immunity to influenza A virus in mice. J. Virol. 74, 3996-4003 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 3996-4003
-
-
Price, G.E.1
Gaszewska-Mastarlarz, A.2
Moskophidis, D.3
-
18
-
-
0034655279
-
Type I IFN modulates innate and specific antiviral immunity
-
Durbin JE, Fernandez-Sesma A, Lee CK et al.: Type I IFN modulates innate and specific antiviral immunity. J. Immunol. 164, 4220-4228 (2000).
-
(2000)
J. Immunol.
, vol.164
, pp. 4220-4228
-
-
Durbin, J.E.1
Fernandez-Sesma, A.2
Lee, C.K.3
-
19
-
-
70349651575
-
Innate immune control and regulation of influenza virus infections
-
McGill J, Heusel JW, Legge KL: Innate immune control and regulation of influenza virus infections. J. Leukoc. Biol. 86, 803-812 (2009).
-
(2009)
J. Leukoc. Biol.
, vol.86
, pp. 803-812
-
-
McGill, J.1
Heusel, J.W.2
Legge, K.L.3
-
20
-
-
67650445798
-
Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant
-
Longhi MP, Trumpfheller C, Idoyaga J et al.: Dendritic cells require a systemic type I interferon response to mature and induce CD4+ Th1 immunity with poly IC as adjuvant. J. Exp. Med. 206, 1589-1602 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 1589-1602
-
-
Longhi, M.P.1
Trumpfheller, C.2
Idoyaga, J.3
-
21
-
-
33750934617
-
Dendritic cells: Translating innate to adaptive immunity
-
Steinman RM, Hemmi H: Dendritic cells: translating innate to adaptive immunity. Curr. Top. Microbiol. Immunol. 311, 17-58 (2006).
-
(2006)
Curr. Top. Microbiol. Immunol.
, vol.311
, pp. 17-58
-
-
Steinman, R.M.1
Hemmi, H.2
-
23
-
-
2342453362
-
Antigenic differences between H5N1 human influenza viruses isolated in 1997 and 2003
-
Horimoto T, Fukuda N, Iwatsuki Horimoto K et al.: Antigenic differences between H5N1 human influenza viruses isolated in 1997 and 2003. J. Vet. Med. Sci. 66, 303-305 (2004).
-
(2004)
J. Vet. Med. Sci.
, vol.66
, pp. 303-305
-
-
Horimoto, T.1
Fukuda, N.2
Iwatsuki Horimoto, K.3
-
24
-
-
33749514992
-
Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus
-
Kash JC, Tumpey TM, Proll SC et al.: Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus. Nature 443, 578-581 (2006).
-
(2006)
Nature
, vol.443
, pp. 578-581
-
-
Kash, J.C.1
Tumpey, T.M.2
Proll, S.C.3
-
25
-
-
33846265834
-
Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus
-
Kobasa D, Jones SM, Shinya K et al.: Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus. Nature 445, 319-323 (2007).
-
(2007)
Nature
, vol.445
, pp. 319-323
-
-
Kobasa, D.1
Jones, S.M.2
Shinya, K.3
-
26
-
-
33749511112
-
Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia
-
de Jong MD, Simmons CP, Thanh TT et al.: Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia. Nat. Med. 12, 1203-1207 (2006).
-
(2006)
Nat. Med.
, vol.12
, pp. 1203-1207
-
-
De Jong, M.D.1
Simmons, C.P.2
Thanh, T.T.3
-
27
-
-
34248170234
-
Avian influenza virus (H5N1): A threat to human health
-
Peiris JS, de Jong MD, Guan Y: Avian influenza virus (H5N1): a threat to human health. Clin. Microbiol. Rev. 20, 243-267 (2007).
-
(2007)
Clin. Microbiol. Rev.
, vol.20
, pp. 243-267
-
-
Peiris, J.S.1
De Jong, M.D.2
Guan, Y.3
-
28
-
-
34547619982
-
Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection
-
Salomon R, Hoffmann E, Webster RG: Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection. Proc. Natl Acad. Sci. USA 104, 12479-12481 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 12479-12481
-
-
Salomon, R.1
Hoffmann, E.2
Webster, R.G.3
-
29
-
-
33947417049
-
Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice
-
Szretter KJ, Gangappa S, Lu X et al.: Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice. J. Virol. 81, 2736-2744 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 2736-2744
-
-
Szretter, K.J.1
Gangappa, S.2
Lu, X.3
-
30
-
-
62549085229
-
Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus
-
Baskin CR, Bielefeldt-Ohmann H, Tumpey TM et al.: Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus. Proc. Natl Acad. Sci. USA 106, 3455-3460 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 3455-3460
-
-
Baskin, C.R.1
Bielefeldt-Ohmann, H.2
Tumpey, T.M.3
-
33
-
-
34347231940
-
Interferon, a growing cytokine family: 50 years of interferon research
-
Chelbi-Alix MK, Wietzerbin J: Interferon, a growing cytokine family: 50 years of interferon research. Biochimie 89, 713-718 (2007).
-
(2007)
Biochimie
, vol.89
, pp. 713-718
-
-
Chelbi-Alix, M.K.1
Wietzerbin, J.2
-
34
-
-
0031878581
-
Protective role of g interferon during the recall response to influenza virus
-
Bot A, Bot S, Bona CA: Protective role of g interferon during the recall response to influenza virus. J. Virol. 72, 6637-6645 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 6637-6645
-
-
Bot, A.1
Bot, S.2
Bona, C.A.3
-
35
-
-
34250212458
-
Disregulated influenza A virus-specific CD8+ T cell homeostasis in the absence of IFN-g signaling
-
Turner SJ, Olivas E, Gutierrez A, Diaz G, Doherty PC: Disregulated influenza A virus-specific CD8+ T cell homeostasis in the absence of IFN-g signaling. J. Immunol. 178, 7616-7622 (2007).
-
(2007)
J. Immunol.
, vol.178
, pp. 7616-7622
-
-
Turner, S.J.1
Olivas, E.2
Gutierrez, A.3
Diaz, G.4
Doherty, P.C.5
-
36
-
-
53049101323
-
Interferon-l contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses
-
Mordstein M, Kochs G, Dumoutier L et al.: Interferon-l contributes to innate immunity of mice against influenza A virus but not against hepatotropic viruses. PLoS Pathog. 4, e1000151 (2008).
-
(2008)
PLoS Pathog.
, vol.4
-
-
Mordstein, M.1
Kochs, G.2
Dumoutier, L.3
-
37
-
-
63149194226
-
Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: Antiviral potential of exogenous a interferon to reduce virus shedding
-
Van Hoeven N, Belser JA, Szretter KJ et al.: Pathogenesis of 1918 pandemic and H5N1 influenza virus infections in a guinea pig model: antiviral potential of exogenous a interferon to reduce virus shedding. J. Virol. 83, 2851-2861 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 2851-2861
-
-
Van Hoeven, N.1
Belser, J.A.2
Szretter, K.J.3
-
38
-
-
0345004816
-
Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems
-
Garcia-Sastre A, Egorov A, Matassov D et al.: Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology 252, 324-330 (1998).
-
(1998)
Virology
, vol.252
, pp. 324-330
-
-
Garcia-Sastre, A.1
Egorov, A.2
Matassov, D.3
-
39
-
-
0031680630
-
The role of interferon in influenza virus tissue tropism
-
Garcia-Sastre A, Durbin RK, Zheng H et al.: The role of interferon in influenza virus tissue tropism. J. Virol. 72, 8550-8558 (1998).
-
(1998)
J. Virol.
, vol.72
, pp. 8550-8558
-
-
Garcia-Sastre, A.1
Durbin, R.K.2
Zheng, H.3
-
40
-
-
66149154715
-
Early control of H5N1 influenza virus replication by the type I interferon response in mice
-
Szretter KJ, Gangappa S, Belser JA et al.: Early control of H5N1 influenza virus replication by the type I interferon response in mice. J. Virol. 83, 5825-5834 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 5825-5834
-
-
Szretter, K.J.1
Gangappa, S.2
Belser, J.A.3
-
41
-
-
64049119567
-
Intranasal administration of a interferon reduces seasonal influenza A virus morbidity in ferrets
-
Kugel D, Kochs G, Obojes K et al.: Intranasal administration of a interferon reduces seasonal influenza A virus morbidity in ferrets. J. Virol. 83, 3843-3851 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 3843-3851
-
-
Kugel, D.1
Kochs, G.2
Obojes, K.3
-
42
-
-
33750984771
-
RIG I-mediated antiviral responses to single-stranded RNA bearing 5́-phosphates
-
Pichlmair A, Schulz O, Tan CP et al.: RIG I-mediated antiviral responses to single-stranded RNA bearing 5́-phosphates. Science 314, 997-1001 (2006).
-
(2006)
Science
, vol.314
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
-
43
-
-
33646453915
-
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses
-
Weber F, Wagner V, Rasmussen SB, Hartmann R, Paludan SR: Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA viruses. J. Virol. 80, 5059-5064 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 5059-5064
-
-
Weber, F.1
Wagner, V.2
Rasmussen, S.B.3
Hartmann, R.4
Paludan, S.R.5
-
44
-
-
66449088641
-
Pathogen recognition and inflammatory signaling in innate immune defenses
-
Table of Contents
-
Mogensen TH: Pathogen recognition and inflammatory signaling in innate immune defenses. Clin. Microbiol. Rev. 22, 240-273, Table of Contents (2009).
-
(2009)
Clin. Microbiol. Rev.
, vol.22
, pp. 240-273
-
-
Mogensen, T.H.1
-
45
-
-
33846014297
-
Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA
-
Kanneganti TD, Body-Malapel M, Amer A et al.: Critical role for cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA. J. Biol. Chem. 281, 36560-36568 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 36560-36568
-
-
Kanneganti, T.D.1
Body-Malapel, M.2
Amer, A.3
-
46
-
-
64049111768
-
The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
-
Allen IC, Scull MA, Moore CB et al.: The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 30, 556-565 (2009).
-
(2009)
Immunity
, vol.30
, pp. 556-565
-
-
Allen, I.C.1
Scull, M.A.2
Moore, C.B.3
-
47
-
-
60549112774
-
Inflammasome recognition of influenza virus is essential for adaptive immune responses
-
Ichinohe T, Lee HK, Ogura Y, Flavell R, Iwasaki A: Inflammasome recognition of influenza virus is essential for adaptive immune responses. J. Exp. Med. 206, 79-87 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 79-87
-
-
Ichinohe, T.1
Lee, H.K.2
Ogura, Y.3
Flavell, R.4
Iwasaki, A.5
-
48
-
-
64049096334
-
The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1
-
Thomas PG, Dash P, Aldridge JR Jr et al.: The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1. Immunity 30, 566-575 (2009).
-
(2009)
Immunity
, vol.30
, pp. 566-575
-
-
Thomas, P.G.1
Dash, P.2
Aldridge Jr., J.R.3
-
50
-
-
5944261457
-
Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
-
Kurt-Jones EA, Popova L, Kwinn L et al.: Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat. Immunol. 1, 398-401 (2000).
-
(2000)
Nat. Immunol.
, vol.1
, pp. 398-401
-
-
Kurt-Jones, E.A.1
Popova, L.2
Kwinn, L.3
-
51
-
-
41949087380
-
Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury
-
Imai Y, Kuba K, Neely GG et al.: Identification of oxidative stress and Toll-like receptor 4 signaling as a key pathway of acute lung injury. Cell 133, 235-249 (2008).
-
(2008)
Cell
, vol.133
, pp. 235-249
-
-
Imai, Y.1
Kuba, K.2
Neely, G.G.3
-
52
-
-
1842631428
-
Recognition of single-stranded RNA viruses by Toll-like receptor 7
-
Lund JM, Alexopoulou L, Sato A et al.: Recognition of single-stranded RNA viruses by Toll-like receptor 7. Proc. Natl Acad. Sci. USA 101, 5598-5603 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 5598-5603
-
-
Lund, J.M.1
Alexopoulou, L.2
Sato, A.3
-
53
-
-
1542317550
-
Reis e Sousa C: Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C: Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 303, 1529-1531 (2004).
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
-
54
-
-
56549116047
-
Toll-like receptor and RIG I-like receptor signaling
-
Kawai T, Akira S: Toll-like receptor and RIG I-like receptor signaling. Ann. NY Acad. Sci. 1143, 1-20 (2008).
-
(2008)
Ann. NY Acad. Sci.
, vol.1143
, pp. 1-20
-
-
Kawai, T.1
Akira, S.2
-
55
-
-
58049217490
-
RNA recognition and signal transduction by RIG I-like receptors
-
Yoneyama M, Fujita T: RNA recognition and signal transduction by RIG I-like receptors. Immunol. Rev. 227, 54-65 (2009).
-
(2009)
Immunol. Rev.
, vol.227
, pp. 54-65
-
-
Yoneyama, M.1
Fujita, T.2
-
57
-
-
37349052379
-
Distinct RIG I and MDA5 signaling by RNA viruses in innate immunity
-
Loo YM, Fornek J, Crochet N et al.: Distinct RIG I and MDA5 signaling by RNA viruses in innate immunity. J. Virol. 82, 335-345 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 335-345
-
-
Loo, Y.M.1
Fornek, J.2
Crochet, N.3
-
58
-
-
33646342149
-
Differential roles of MDA5 and RIG I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S et al.: Differential roles of MDA5 and RIG I helicases in the recognition of RNA viruses. Nature 441, 101-105 (2006).
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
-
59
-
-
3242813113
-
The RNA helicase RIG I has an essential function in double-stranded RNA-induced innate antiviral responses
-
Yoneyama M, Kikuchi M, Natsukawa T et al.: The RNA helicase RIG I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730-737 (2004).
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
Kikuchi, M.2
Natsukawa, T.3
-
60
-
-
48949094095
-
Structural mechanism of RNA recognition by the RIG I-like receptors
-
Yoneyama M, Fujita T: Structural mechanism of RNA recognition by the RIG I-like receptors. Immunity 29, 178-181 (2008).
-
(2008)
Immunity
, vol.29
, pp. 178-181
-
-
Yoneyama, M.1
Fujita, T.2
-
61
-
-
34247341367
-
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG I-mediated antiviral activity
-
Gack MU, Shin YC, Joo CH et al.: TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG I-mediated antiviral activity. Nature 446, 916-920 (2007).
-
(2007)
Nature
, vol.446
, pp. 916-920
-
-
Gack, M.U.1
Shin, Y.C.2
Joo, C.H.3
-
62
-
-
27144440523
-
IPS-1, an adaptor triggering RIG I- and Mda5- mediated type I interferon induction
-
Kawai T, Takahashi K, Sato S et al.: IPS-1, an adaptor triggering RIG I- and Mda5- mediated type I interferon induction. Nat. Immunol. 6, 981-988 (2005).
-
(2005)
Nat. Immunol.
, vol.6
, pp. 981-988
-
-
Kawai, T.1
Takahashi, K.2
Sato, S.3
-
63
-
-
33745814424
-
Essential role of IPS-1 in innate immune responses against RNA viruses
-
Kumar H, Kawai T, Kato H et al.: Essential role of IPS-1 in innate immune responses against RNA viruses. J. Exp. Med. 203, 1795 - 1803 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1795-1803
-
-
Kumar, H.1
Kawai, T.2
Kato, H.3
-
64
-
-
56749133272
-
Viral evasion and subversion of pattern-recognition receptor signalling
-
Bowie AG, Unterholzner L: Viral evasion and subversion of pattern-recognition receptor signalling. Nat. Rev. Immunol. 8, 911-922 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 911-922
-
-
Bowie, A.G.1
Unterholzner, L.2
-
65
-
-
44649119259
-
Regulation of mitochondrial antiviral signaling pathways
-
Moore CB, Ting JP: Regulation of mitochondrial antiviral signaling pathways. Immunity 28, 735-739 (2008).
-
(2008)
Immunity
, vol.28
, pp. 735-739
-
-
Moore, C.B.1
Ting, J.P.2
-
66
-
-
46249115827
-
Interferon-inducible antiviral effectors
-
Sadler AJ, Williams BR: Interferon-inducible antiviral effectors. Nat. Rev. Immunol. 8, 559-568 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 559-568
-
-
Sadler, A.J.1
Williams, B.R.2
-
67
-
-
0032417696
-
Identification of genes differentially regulated by interferon a, b, or g using oligonucleotide arrays
-
Der SD, Zhou A, Williams BR, Silverman RH: Identification of genes differentially regulated by interferon a, b, or g using oligonucleotide arrays. Proc. Natl Acad. Sci. USA 95, 15623-15628 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 15623-15628
-
-
Der, S.D.1
Zhou, A.2
Williams, B.R.3
Silverman, R.H.4
-
68
-
-
33845627785
-
Impact of protein kinase PKR in cell biology: From antiviral to antiproliferative action
-
Garcia MA, Gil J, Ventoso I et al.: Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action. Microbiol. Mol. Biol. Rev. 70, 1032-1060 (2006).
-
(2006)
Microbiol. Mol. Biol. Rev.
, vol.70
, pp. 1032-1060
-
-
Garcia, M.A.1
Gil, J.2
Ventoso, I.3
-
69
-
-
36348987303
-
Viral encounters with 2́,5́-oligoadenylate synthetase and RNase L during the interferon antiviral response
-
Silverman RH: Viral encounters with 2́,5́-oligoadenylate synthetase and RNase L during the interferon antiviral response. J. Virol. 81, 12720-12729 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 12720-12729
-
-
Silverman, R.H.1
-
70
-
-
68149098653
-
Protective role of interferon-induced Mx GTPases against influenza viruses
-
Haller O, Staeheli P, Kochs G: Protective role of interferon-induced Mx GTPases against influenza viruses. Rev. Sci. Tech. 28, 219-231 (2009).
-
(2009)
Rev. Sci. Tech.
, vol.28
, pp. 219-231
-
-
Haller, O.1
Staeheli, P.2
Kochs, G.3
-
71
-
-
34547656276
-
The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts
-
Wang X, Hinson ER, Cresswell P: The interferon-inducible protein viperin inhibits influenza virus release by perturbing lipid rafts. Cell Host Microbe 2, 96-105 (2007).
-
(2007)
Cell Host Microbe
, vol.2
, pp. 96-105
-
-
Wang, X.1
Hinson, E.R.2
Cresswell, P.3
-
72
-
-
33846603312
-
IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses
-
Lenschow DJ, Lai C, Frias-Staheli N et al.: IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proc. Natl Acad. Sci. USA 104, 1371-1376 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 1371-1376
-
-
Lenschow, D.J.1
Lai, C.2
Frias-Staheli, N.3
-
73
-
-
58149502576
-
Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection
-
Lai C, Struckhoff JJ, Schneider J et al.: Mice lacking the ISG15 E1 enzyme UbE1L demonstrate increased susceptibility to both mouse-adapted and non-mouse-adapted influenza B virus infection. J. Virol. 83, 1147-1151 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 1147-1151
-
-
Lai, C.1
Struckhoff, J.J.2
Schneider, J.3
-
74
-
-
33645037542
-
Variation in the ability of human influenza A viruses to induce and inhibit the IFN-β pathway
-
Hayman A, Comely S, Lackenby A et al.: Variation in the ability of human influenza A viruses to induce and inhibit the IFN-β pathway. Virology 347, 52-64 (2006).
-
(2006)
Virology
, vol.347
, pp. 52-64
-
-
Hayman, A.1
Comely, S.2
Lackenby, A.3
-
75
-
-
54449099369
-
The multifunctional NS1 protein of influenza A viruses
-
Hale BG, Randall RE, Ortin J, Jackson D: The multifunctional NS1 protein of influenza A viruses. J. Gen. Virol. 89, 2359-2376 (2008).
-
(2008)
J. Gen. Virol.
, vol.89
, pp. 2359-2376
-
-
Hale, B.G.1
Randall, R.E.2
Ortin, J.3
Jackson, D.4
-
76
-
-
0034636103
-
Influenza A and B viruses expressing altered NS1 proteins: A vaccine approach
-
Talon J, Salvatore M, O'Neill RE et al.: Influenza A and B viruses expressing altered NS1 proteins: a vaccine approach. Proc. Natl Acad. Sci. USA 97, 4309-4314 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 4309-4314
-
-
Talon, J.1
Salvatore, M.2
O'Neill, R.E.3
-
77
-
-
26244458739
-
Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins
-
Falcon AM, Fernandez-Sesma A, Nakaya Y, Moran TM, Ortin J, Garcia-Sastre A: Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins. J. Gen. Virol. 86, 2817-2821 (2005).
-
(2005)
J. Gen. Virol.
, vol.86
, pp. 2817-2821
-
-
Falcon, A.M.1
Fernandez-Sesma, A.2
Nakaya, Y.3
Moran, T.M.4
Ortin, J.5
Garcia-Sastre, A.6
-
78
-
-
20744448799
-
Attenuation of equine influenza viruses through truncations of the NS1 protein
-
Quinlivan M, Zamarin D, Garcia-Sastre A, Cullinane A, Chambers T, Palese P: Attenuation of equine influenza viruses through truncations of the NS1 protein. J. Virol. 79, 8431-8439 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 8431-8439
-
-
Quinlivan, M.1
Zamarin, D.2
Garcia-Sastre, A.3
Cullinane, A.4
Chambers, T.5
Palese, P.6
-
79
-
-
19944419799
-
Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
-
Solorzano A, Webby RJ, Lager KM, Janke BH, Garcia-Sastre A, Richt JA: Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J. Virol. 79, 7535-7543 (2005).
-
(2005)
J. Virol.
, vol.79
, pp. 7535-7543
-
-
Solorzano, A.1
Webby, R.J.2
Lager, K.M.3
Janke, B.H.4
Garcia-Sastre, A.5
Richt, J.A.6
-
80
-
-
59649084891
-
Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza
-
Steel J, Lowen AC, Pena L et al.: Live attenuated influenza viruses containing NS1 truncations as vaccine candidates against H5N1 highly pathogenic avian influenza. J. Virol. 83, 1742-1753 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 1742-1753
-
-
Steel, J.1
Lowen, A.C.2
Pena, L.3
-
81
-
-
58549085205
-
Influenza A viruses with truncated NS1 as modified live virus vaccines: Pilot studies of safety and efficacy in horses
-
Chambers TM, Quinlivan M, Sturgill T et al.: Influenza A viruses with truncated NS1 as modified live virus vaccines: pilot studies of safety and efficacy in horses. Equine Vet. J. 41, 87-92 (2009).
-
(2009)
Equine Vet. J.
, vol.41
, pp. 87-92
-
-
Chambers, T.M.1
Quinlivan, M.2
Sturgill, T.3
-
82
-
-
8644243888
-
Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes
-
Ferko B, Stasakova J, Romanova J et al.: Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes. J. Virol. 78, 13037-13045 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 13037-13045
-
-
Ferko, B.1
Stasakova, J.2
Romanova, J.3
-
83
-
-
0345167006
-
A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of b interferon and is attenuated in mice
-
Donelan NR, Basler CF, Garcia-Sastre A: A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of b interferon and is attenuated in mice. J. Virol. 77, 13257-13266 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 13257-13266
-
-
Donelan, N.R.1
Basler, C.F.2
Garcia-Sastre, A.3
-
84
-
-
33750719677
-
Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine
-
Richt JA, Lekcharoensuk P, Lager KM et al.: Vaccination of pigs against swine influenza viruses by using an NS1-truncated modified live-virus vaccine. J. Virol. 80, 11009-11018 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 11009-11018
-
-
Richt, J.A.1
Lekcharoensuk, P.2
Lager, K.M.3
-
85
-
-
35548976678
-
Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine
-
Vincent AL, Ma W, Lager KM et al.: Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine. Vaccine 25, 7999-8009 (2007).
-
(2007)
Vaccine
, vol.25
, pp. 7999-8009
-
-
Vincent, A.L.1
Ma, W.2
Lager, K.M.3
-
86
-
-
35448980010
-
Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus
-
Baskin CR, Bielefeldt-Ohmann H, Garcia-Sastre A et al.: Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus. J. Virol. 81, 11817-11827 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 11817-11827
-
-
Baskin, C.R.1
Bielefeldt-Ohmann, H.2
Garcia-Sastre, A.3
-
87
-
-
70349328104
-
Cutting edge: Stealth influenza virus replication precedes the initiation of adaptive immunity
-
Moltedo B, Lopez CB, Pazos M, Becker MI, Hermesh T, Moran TM: Cutting edge: stealth influenza virus replication precedes the initiation of adaptive immunity. J. Immunol. 183, 3569-3573 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 3569-3573
-
-
Moltedo, B.1
Lopez, C.B.2
Pazos, M.3
Becker, M.I.4
Hermesh, T.5
Moran, T.M.6
-
88
-
-
0842304509
-
The influenza B virus nonstructural NS1 protein is essential for efficient viral growth and antagonizes b interferon induction
-
Dauber B, Heins G, Wolff T: The influenza B virus nonstructural NS1 protein is essential for efficient viral growth and antagonizes b interferon induction. J. Virol. 78, 1865-1872 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 1865-1872
-
-
Dauber, B.1
Heins, G.2
Wolff, T.3
-
89
-
-
6344278510
-
The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF 3 and b interferon promoter activation
-
Donelan NR, Dauber B, Wang X, Basler CF, Wolff T, Garcia-Sastre A: The N- and C-terminal domains of the NS1 protein of influenza B virus can independently inhibit IRF 3 and b interferon promoter activation. J. Virol. 78, 11574-11582 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 11574-11582
-
-
Donelan, N.R.1
Dauber, B.2
Wang, X.3
Basler, C.F.4
Wolff, T.5
Garcia-Sastre, A.6
-
90
-
-
0033870894
-
Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein
-
Talon J, Horvath CM, Polley R et al.: Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J. Virol. 74, 7989-7996 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 7989-7996
-
-
Talon, J.1
Horvath, C.M.2
Polley, R.3
-
91
-
-
0034466776
-
Influenza A virus NS1 protein prevents activation of NF kB and induction of α/β interferon
-
Wang X, Li M, Zheng H et al.: Influenza A virus NS1 protein prevents activation of NF kB and induction of a/b interferon. J. Virol. 74, 11566-11573 (2000).
-
(2000)
J. Virol.
, vol.74
, pp. 11566-11573
-
-
Wang, X.1
Li, M.2
Zheng, H.3
-
92
-
-
0036838725
-
The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors
-
Ludwig S, Wang X, Ehrhardt C et al.: The influenza A virus NS1 protein inhibits activation of Jun N-terminal kinase and AP-1 transcription factors. J. Virol. 76, 11166-11171 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 11166-11171
-
-
Ludwig, S.1
Wang, X.2
Ehrhardt, C.3
-
93
-
-
33847670199
-
NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor RIG-I
-
Guo Z, Chen LM, Zeng H et al.: NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG I. Am. J. Respir. Cell Mol. Biol. 36, 263-269 (2007).
-
(2007)
Am. J. Respir. Cell Mol. Biol.
, vol.36
, pp. 263-269
-
-
Guo, Z.1
Chen, L.M.2
Zeng, H.3
-
94
-
-
33947171000
-
IFNb induction by influenza A virus is mediated by RIG I which is regulated by the viral NS1 protein
-
Opitz B, Rejaibi A, Dauber B et al.: IFNb induction by influenza A virus is mediated by RIG I which is regulated by the viral NS1 protein. Cell. Microbiol. 9, 930-938 (2007).
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 930-938
-
-
Opitz, B.1
Rejaibi, A.2
Dauber, B.3
-
95
-
-
33846061693
-
Inhibition of retinoic acid-inducible gene I-mediated induction of b interferon by the NS1 protein of influenza A virus
-
Mibayashi M, Martinez-Sobrido L, Loo YM, Cardenas WB, Gale M Jr, Garcia-Sastre A: Inhibition of retinoic acid-inducible gene I-mediated induction of b interferon by the NS1 protein of influenza A virus. J. Virol. 81, 514-524 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 514-524
-
-
Mibayashi, M.1
Martinez-Sobrido, L.2
Loo, Y.M.3
Cardenas, W.B.4
Gale Jr., M.5
Garcia-Sastre, A.6
-
96
-
-
67649185871
-
Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7
-
Genin P, Lin R, Hiscott J, Civas A: Differential regulation of human interferon A gene expression by interferon regulatory factors 3 and 7. Mol. Cell. Biol. 29, 3435-3450 (2009).
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3435-3450
-
-
Genin, P.1
Lin, R.2
Hiscott, J.3
Civas, A.4
-
97
-
-
65549164536
-
Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG I
-
Gack MU, Albrecht RA, Urano T et al.: Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG I. Cell Host Microbe 5, 439-449 (2009).
-
(2009)
Cell Host Microbe
, vol.5
, pp. 439-449
-
-
Gack, M.U.1
Albrecht, R.A.2
Urano, T.3
-
98
-
-
54949126675
-
Morse HC 3rd: TRIM family proteins and their emerging roles in innate immunity
-
Ozato K, Shin DM, Chang TH, Morse HC 3rd: TRIM family proteins and their emerging roles in innate immunity. Nat. Rev. Immunol. 8, 849-860 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 849-860
-
-
Ozato, K.1
Shin, D.M.2
Chang, T.H.3
-
99
-
-
55949131282
-
Roles of RIG I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction
-
Gack MU, Kirchhofer A, Shin YC et al.: Roles of RIG I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction. Proc. Natl Acad. Sci. USA 105, 16743-16748 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 16743-16748
-
-
Gack, M.U.1
Kirchhofer, A.2
Shin, Y.C.3
-
100
-
-
0037142070
-
EFP targets 14-13-3 s for proteolysis and promotes breast tumour growth
-
Urano T, Saito T, Tsukui T et al.: EFP targets 14-13-3 s for proteolysis and promotes breast tumour growth. Nature 417, 871-875 (2002).
-
(2002)
Nature
, vol.417
, pp. 871-875
-
-
Urano, T.1
Saito, T.2
Tsukui, T.3
-
101
-
-
33645217490
-
The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase
-
Zou W, Zhang DE: The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase. J. Biol. Chem. 281, 3989-3994 (2006).
-
(2006)
J. Biol. Chem.
, Issue.281
, pp. 3989-3994
-
-
Zou, W.1
Zhang, D.E.2
-
102
-
-
0032086357
-
Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3́ end formation of cellular pre-mRNAs
-
Nemeroff ME, Barabino SM, Li Y, Keller W, Krug RM: Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3́ end formation of cellular pre-mRNAs. Mol. Cell 1, 991-1000 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 991-1000
-
-
Nemeroff, M.E.1
Barabino, S.M.2
Li, Y.3
Keller, W.4
Krug, R.M.5
-
103
-
-
34250810666
-
Multiple anti-interferon actions of the influenza A virus NS1 protein
-
Kochs G, Garcia-Sastre A, Martinez Sobrido L: Multiple anti-interferon actions of the influenza A virus NS1 protein. J. Virol. 81, 7011-7021 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 7011-7021
-
-
Kochs, G.1
Garcia-Sastre, A.2
Martinez Sobrido, L.3
-
104
-
-
0037444193
-
Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3́ end processing of cellular pre-mRNAS
-
Noah DL, Twu KY, Krug RM: Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3́ end processing of cellular pre-mRNAS. Virology 307, 386-395 (2003).
-
(2003)
Virology
, vol.307
, pp. 386-395
-
-
Noah, D.L.1
Twu, K.Y.2
Krug, R.M.3
-
105
-
-
33645792617
-
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target
-
Twu KY, Noah DL, Rao P, Kuo RL, Krug RM: The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target. J. Virol. 80, 3957-3965 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 3957-3965
-
-
Twu, K.Y.1
Noah, D.L.2
Rao, P.3
Kuo, R.L.4
Krug, R.M.5
-
106
-
-
0028008470
-
Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport
-
Fortes P, Beloso A, Ortin J: Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J. 13, 704-712 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 704-712
-
-
Fortes, P.1
Beloso, A.2
Ortin, J.3
-
107
-
-
0028040760
-
The influenza virus NS1 protein: A novel inhibitor of pre-mRNA splicing
-
Lu Y, Qian XY, Krug RM: The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing. Genes Dev. 8, 1817-1828 (1994).
-
(1994)
Genes Dev.
, vol.8
, pp. 1817-1828
-
-
Lu, Y.1
Qian, X.Y.2
Krug, R.M.3
-
108
-
-
0034743629
-
The 3́-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo
-
Li Y, Chen ZY, Wang W, Baker CC, Krug RM: The 3́-end-processing factor CPSF is required for the splicing of single-intron pre-mRNAs in vivo. RNA 7, 920-931 (2001).
-
(2001)
RNA
, vol.7
, pp. 920-931
-
-
Li, Y.1
Chen, Z.Y.2
Wang, W.3
Baker, C.C.4
Krug, R.M.5
-
109
-
-
51349124912
-
Structural basis for suppression of a host antiviral response by influenza A virus
-
Das K, Ma LC, Xiao R et al.: Structural basis for suppression of a host antiviral response by influenza A virus. Proc. Natl Acad. Sci. USA 105, 13093-13098 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 13093-13098
-
-
Das, K.1
Ma, L.C.2
Xiao, R.3
-
110
-
-
34547110101
-
The H5N1 influenza virus NS genes selected after 1998 enhance virus replication in mammalian cells
-
Twu KY, Kuo RL, Marklund J, Krug RM: The H5N1 influenza virus NS genes selected after 1998 enhance virus replication in mammalian cells. J. Virol. 81, 8112-8121 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 8112-8121
-
-
Twu, K.Y.1
Kuo, R.L.2
Marklund, J.3
Krug, R.M.4
-
111
-
-
0028274131
-
The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A)
-
Qiu Y, Krug RM: The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A). J. Virol. 68, 2425-2432 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 2425-2432
-
-
Qiu, Y.1
Krug, R.M.2
-
112
-
-
0028209823
-
Two functional domains of the influenza virus NS1 protein are required for regulation of nuclear export of mRNA
-
Qian XY, Alonso-Caplen F, Krug RM: Two functional domains of the influenza virus NS1 protein are required for regulation of nuclear export of mRNA. J. Virol. 68, 2433-2441 (1994).
-
(1994)
J. Virol.
, vol.68
, pp. 2433-2441
-
-
Qian, X.Y.1
Alonso-Caplen, F.2
Krug, R.M.3
-
113
-
-
33846907343
-
Influenza virus targets the mRNA export machinery and the nuclear pore complex
-
Satterly N, Tsai PL, van Deursen J et al.: Influenza virus targets the mRNA export machinery and the nuclear pore complex. Proc. Natl Acad. Sci. USA 104, 1853-1858 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 1853-1858
-
-
Satterly, N.1
Tsai, P.L.2
Van Deursen, J.3
-
114
-
-
70349737879
-
The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways
-
Billharz R, Zeng H, Proll SC et al.: The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways. J. Virol. 83, 10557-10570 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 10557-10570
-
-
Billharz, R.1
Zeng, H.2
Proll, S.C.3
-
115
-
-
0019394947
-
A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription
-
Plotch SJ, Bouloy M, Ulmanen I, Krug RM: A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription. Cell 23, 847-858 (1981).
-
(1981)
Cell
, vol.23
, pp. 847-858
-
-
Plotch, S.J.1
Bouloy, M.2
Ulmanen, I.3
Krug, R.M.4
-
116
-
-
43249128376
-
The structural basis for cap binding by influenza virus polymerase subunit PB2
-
Guilligay D, Tarendeau F, Resa-Infante P et al.: The structural basis for cap binding by influenza virus polymerase subunit PB2. Nat. Struct. Mol. Biol. 15, 500-506 (2008).
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 500-506
-
-
Guilligay, D.1
Tarendeau, F.2
Resa-Infante, P.3
-
117
-
-
67649552964
-
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase
-
Sugiyama K, Obayashi E, Kawaguchi A et al.: Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase. EMBO J. 28, 1803-1811 (2009).
-
(2009)
EMBO J.
, vol.28
, pp. 1803-1811
-
-
Sugiyama, K.1
Obayashi, E.2
Kawaguchi, A.3
-
118
-
-
67249130012
-
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
-
Dias A, Bouvier D, Crepin T et al.: The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit. Nature 458, 914-918 (2009).
-
(2009)
Nature
, vol.458
, pp. 914-918
-
-
Dias, A.1
Bouvier, D.2
Crepin, T.3
-
119
-
-
67249100913
-
Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site
-
Yuan P, Bartlam M, Lou Z et al.: Crystal structure of an avian influenza polymerase PA(N) reveals an endonuclease active site. Nature 458, 909-913 (2009).
-
(2009)
Nature
, vol.458
, pp. 909-913
-
-
Yuan, P.1
Bartlam, M.2
Lou, Z.3
-
120
-
-
59649123636
-
Influenza A virus polymerase is an integral component of the CPSF30-NS1A protein complex in infected cells
-
Kuo RL, Krug RM: Influenza A virus polymerase is an integral component of the CPSF30-NS1A protein complex in infected cells. J. Virol. 83, 1611-1616 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 1611-1616
-
-
Kuo, R.L.1
Krug, R.M.2
-
121
-
-
49649101318
-
Influenza A virus abrogates IFN-g response in respiratory epithelial cells by disruption of the Jak/Stat pathway
-
Uetani K, Hiroi M, Meguro T et al.: Influenza A virus abrogates IFN-g response in respiratory epithelial cells by disruption of the Jak/Stat pathway. Eur. J. Immunol. 38, 1559-1573 (2008).
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1559-1573
-
-
Uetani, K.1
Hiroi, M.2
Meguro, T.3
-
122
-
-
57149092384
-
Influenza A virus inhibits type I IFN signaling via NF kB-dependent induction of SOCS-3 expression
-
Pauli EK, Schmolke M, Wolff T et al.: Influenza A virus inhibits type I IFN signaling via NF kB-dependent induction of SOCS-3 expression. PLoS Pathog. 4, e1000196 (2008).
-
(2008)
PLoS Pathog.
, vol.4
-
-
Pauli, E.K.1
Schmolke, M.2
Wolff, T.3
-
123
-
-
42149119018
-
Cutting edge: Innate immune response triggered by influenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG I/IFNAR1-dependent pathway
-
Pothlichet J, Chignard M, Si-Tahar M: Cutting edge: innate immune response triggered by influenza A virus is negatively regulated by SOCS1 and SOCS3 through a RIG I/IFNAR1-dependent pathway. J. Immunol. 180, 2034-2038 (2008).
-
(2008)
J. Immunol.
, vol.180
, pp. 2034-2038
-
-
Pothlichet, J.1
Chignard, M.2
Si-Tahar, M.3
-
124
-
-
0036734038
-
Lethal H5N1 influenza viruses escape host anti-viral cytokine responses
-
Seo SH, Hoffmann E, Webster RG: Lethal H5N1 influenza viruses escape host anti-viral cytokine responses. Nat. Med. 8, 950-954 (2002).
-
(2002)
Nat. Med.
, vol.8
, pp. 950-954
-
-
Seo, S.H.1
Hoffmann, E.2
Webster, R.G.3
-
125
-
-
0023708282
-
Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase
-
Katze MG, Tomita J, Black T, Krug RM, Safer B, Hovanessian A: Influenza virus regulates protein synthesis during infection by repressing autophosphorylation and activity of the cellular 68,000-Mr protein kinase. J. Virol. 62, 3710-3717 (1988).
-
(1988)
J. Virol.
, vol.62
, pp. 3710-3717
-
-
Katze, M.G.1
Tomita, J.2
Black, T.3
Krug, R.M.4
Safer, B.5
Hovanessian, A.6
-
126
-
-
0025180598
-
Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells
-
Lee TG, Tomita J, Hovanessian AG, Katze MG: Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells. Proc. Natl Acad. Sci. USA 87, 6208-6212 (1990).
-
(1990)
Proc. Natl Acad. Sci. USA
, vol.87
, pp. 6208-6212
-
-
Lee, T.G.1
Tomita, J.2
Hovanessian, A.G.3
Katze, M.G.4
-
127
-
-
0026628369
-
Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase
-
Lee TG, Tomita J, Hovanessian AG, Katze MG: Characterization and regulation of the 58,000-dalton cellular inhibitor of the interferon-induced, dsRNA-activated protein kinase. J. Biol. Chem. 267, 14238-14243 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14238-14243
-
-
Lee, T.G.1
Tomita, J.2
Hovanessian, A.G.3
Katze, M.G.4
-
128
-
-
0031013877
-
The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR
-
Melville MW, Hansen WJ, Freeman BC, Welch WJ, Katze MG: The molecular chaperone hsp40 regulates the activity of P58IPK, the cellular inhibitor of PKR. Proc. Natl Acad. Sci. USA 94, 97-102 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 97-102
-
-
Melville, M.W.1
Hansen, W.J.2
Freeman, B.C.3
Welch, W.J.4
Katze, M.G.5
-
129
-
-
0033525168
-
The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity
-
Melville MW, Tan SL, Wambach M, Song J, Morimoto RI, Katze MG: The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity. J. Biol. Chem. 274, 3797-3803 (1999).
-
(1999)
J. Biol. Chem.
, Issue.274
, pp. 3797-3803
-
-
Melville, M.W.1
Tan, S.L.2
Wambach, M.3
Song, J.4
Morimoto, R.I.5
Katze, M.G.6
-
130
-
-
33646517711
-
Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA
-
Li S, Min JY, Krug RM, Sen GC: Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology 349, 13-21 (2006).
-
(2006)
Virology
, vol.349
, pp. 13-21
-
-
Li, S.1
Min, J.Y.2
Krug, R.M.3
Sen, G.C.4
-
131
-
-
67650917895
-
Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR
-
Dauber B, Martinez-Sobrido L, Schneider J et al.: Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR. PLoS Pathog. 5, e1000473 (2009).
-
(2009)
PLoS Pathog.
, vol.5
-
-
Dauber, B.1
Martinez-Sobrido, L.2
Schneider, J.3
-
132
-
-
33751242334
-
Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of α/β interferon
-
Dauber B, Schneider J, Wolff T: Double-stranded RNA binding of influenza B virus nonstructural NS1 protein inhibits protein kinase R but is not essential to antagonize production of α/β interferon. J. Virol. 80, 11667-11677 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 11667-11677
-
-
Dauber, B.1
Schneider, J.2
Wolff, T.3
-
133
-
-
0035253852
-
Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein
-
Yuan W, Krug RM: Influenza B virus NS1 protein inhibits conjugation of the interferon (IFN)-induced ubiquitin-like ISG15 protein. EMBO J. 20, 362-371 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 362-371
-
-
Yuan, W.1
Krug, R.M.2
-
134
-
-
45149122553
-
Different roles for two ubiquitin-like domains of ISG15 in protein modification
-
Chang YG, Yan XZ, Xie YY et al.: Different roles for two ubiquitin-like domains of ISG15 in protein modification. J. Biol. Chem. 283, 13370-13377 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13370-13377
-
-
Chang, Y.G.1
Yan, X.Z.2
Xie, Y.Y.3
-
135
-
-
41149143074
-
Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase
-
Dittmann J, Stertz S, Grimm D et al.: Influenza A virus strains differ in sensitivity to the antiviral action of Mx-GTPase. J. Virol. 82, 3624-3631 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 3624-3631
-
-
Dittmann, J.1
Stertz, S.2
Grimm, D.3
-
136
-
-
67449101824
-
Adaptive mutations resulting in enhanced polymerase activity contribute to high virulence of influenza A virus in mice
-
Rolling T, Koerner I, Zimmermann P et al.: Adaptive mutations resulting in enhanced polymerase activity contribute to high virulence of influenza A virus in mice. J. Virol. 83, 6673-6680 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 6673-6680
-
-
Rolling, T.1
Koerner, I.2
Zimmermann, P.3
-
137
-
-
34249857885
-
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene
-
Grimm D, Staeheli P, Hufbauer M et al.: Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance gene. Proc. Natl Acad. Sci. USA 104, 6806-6811 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 6806-6811
-
-
Grimm, D.1
Staeheli, P.2
Hufbauer, M.3
-
138
-
-
0033124625
-
Influenza virus overcomes apoptosis by rapid multiplication
-
Kurokawa M, Koyama AH, Yasuoka S, Adachi A: Influenza virus overcomes apoptosis by rapid multiplication. Int. J. Mol. Med. 3, 527-530 (1999).
-
(1999)
Int. J. Mol. Med.
, vol.3
, pp. 527-530
-
-
Kurokawa, M.1
Koyama, A.H.2
Yasuoka, S.3
Adachi, A.4
-
139
-
-
34250828457
-
Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling
-
Zhirnov OP, Klenk HD: Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling. Apoptosis 12, 1419-1432 (2007).
-
(2007)
Apoptosis
, vol.12
, pp. 1419-1432
-
-
Zhirnov, O.P.1
Klenk, H.D.2
-
140
-
-
0036148072
-
NS1 protein of influenza A virus down-regulates apoptosis
-
Zhirnov OP, Konakova TE, Wolff T, Klenk HD: NS1 protein of influenza A virus down-regulates apoptosis. J. Virol. 76, 1617-1625 (2002).
-
(2002)
J. Virol.
, vol.76
, pp. 1617-1625
-
-
Zhirnov, O.P.1
Konakova, T.E.2
Wolff, T.3
Klenk, H.D.4
-
141
-
-
33947381763
-
Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses
-
Ehrhardt C, Wolff T, Pleschka S et al.: Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses. J. Virol. 81, 3058-3067 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 3058-3067
-
-
Ehrhardt, C.1
Wolff, T.2
Pleschka, S.3
-
142
-
-
36349018937
-
SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation
-
Shin YK, Li Y, Liu Q, Anderson DH, Babiuk LA, Zhou Y: SH3 binding motif 1 in influenza A virus NS1 protein is essential for PI3K/Akt signaling pathway activation. J. Virol. 81, 12730-12739 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 12730-12739
-
-
Shin, Y.K.1
Li, Y.2
Liu, Q.3
Anderson, D.H.4
Babiuk, L.A.5
Zhou, Y.6
-
143
-
-
67449106151
-
Differential regulation of antiviral and proinflammatory cytokines and suppression of Fas-mediated apoptosis by NS1 of H9N2 avian influenza virus in chicken macrophages
-
Xing Z, Cardona CJ, Adams S et al.: Differential regulation of antiviral and proinflammatory cytokines and suppression of Fas-mediated apoptosis by NS1 of H9N2 avian influenza virus in chicken macrophages. J. Gen. Virol. 90, 1109-1118 (2009).
-
(2009)
J. Gen. Virol.
, vol.90
, pp. 1109-1118
-
-
Xing, Z.1
Cardona, C.J.2
Adams, S.3
-
144
-
-
35448948397
-
Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses
-
Ehrhardt C, Wolff T, Ludwig S: Activation of phosphatidylinositol 3-kinase signaling by the nonstructural NS1 protein is not conserved among type A and B influenza viruses. J. Virol. 81, 12097-12100 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 12097-12100
-
-
Ehrhardt, C.1
Wolff, T.2
Ludwig, S.3
-
145
-
-
69449083335
-
Influenza virus directly infects human natural killer cells and induces cell apoptosis
-
Epub ahead of print
-
Mao H, Tu W, Qin G et al.: Influenza virus directly infects human natural killer cells and induces cell apoptosis. J. Virol. (2009) (Epub ahead of print).
-
(2009)
J. Virol.
-
-
Mao, H.1
Tu, W.2
Qin, G.3
-
146
-
-
0035658084
-
A novel influenza A virus mitochondrial protein that induces cell death
-
Chen W, Calvo PA, Malide D et al.: A novel influenza A virus mitochondrial protein that induces cell death. Nat. Med. 7, 1306-1312 (2001).
-
(2001)
Nat. Med.
, vol.7
, pp. 1306-1312
-
-
Chen, W.1
Calvo, P.A.2
Malide, D.3
-
147
-
-
0038001672
-
The influenza A virus PB1 F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function
-
Gibbs JS, Malide D, Hornung F, Bennink JR, Yewdell JW: The influenza A virus PB1 F2 protein targets the inner mitochondrial membrane via a predicted basic amphipathic helix that disrupts mitochondrial function. J. Virol. 77, 7214-7224 (2003).
-
(2003)
J. Virol.
, vol.77
, pp. 7214-7224
-
-
Gibbs, J.S.1
Malide, D.2
Hornung, F.3
Bennink, J.R.4
Yewdell, J.W.5
-
148
-
-
10044257654
-
Mitochondrial targeting sequence of the influenza A virus PB1 F2 protein and its function in mitochondria
-
Yamada H, Chounan R, Higashi Y, Kurihara N, Kido H: Mitochondrial targeting sequence of the influenza A virus PB1 F2 protein and its function in mitochondria. FEBS Lett. 578, 331-336 (2004).
-
(2004)
FEBS Lett.
, vol.578
, pp. 331-336
-
-
Yamada, H.1
Chounan, R.2
Higashi, Y.3
Kurihara, N.4
Kido, H.5
-
149
-
-
2642542356
-
PB1 F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes
-
Chanturiya AN, Basanez G, Schubert U, Henklein P, Yewdell JW, Zimmerberg J: PB1 F2, an influenza A virus-encoded proapoptotic mitochondrial protein, creates variably sized pores in planar lipid membranes. J. Virol. 78, 6304-6312 (2004).
-
(2004)
J. Virol.
, vol.78
, pp. 6304-6312
-
-
Chanturiya, A.N.1
Basanez, G.2
Schubert, U.3
Henklein, P.4
Yewdell, J.W.5
Zimmerberg, J.6
-
150
-
-
77951059450
-
Influenza virus PB1 F2 protein induces cell death through mitochondrial ANT3 and VDAC1
-
Zamarin D, Garcia-Sastre A, Xiao X, Wang R, Palese P: Influenza virus PB1 F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS Pathog. 1, e4 (2005).
-
(2005)
PLoS Pathog.
, vol.1
-
-
Zamarin, D.1
Garcia-Sastre, A.2
Xiao, X.3
Wang, R.4
Palese, P.5
-
151
-
-
0035657923
-
Death by influenza virus protein
-
Lamb RA, Takeda M: Death by influenza virus protein. Nat. Med. 7, 1286-1288 (2001).
-
(2001)
Nat. Med.
, vol.7
, pp. 1286-1288
-
-
Lamb, R.A.1
Takeda, M.2
-
152
-
-
33746858906
-
Influenza A virus PB1 F2 protein contributes to viral pathogenesis in mice
-
Zamarin D, Ortigoza MB, Palese P: Influenza A virus PB1 F2 protein contributes to viral pathogenesis in mice. J. Virol. 80, 7976-7983 (2006).
-
(2006)
J. Virol.
, vol.80
, pp. 7976-7983
-
-
Zamarin, D.1
Ortigoza, M.B.2
Palese, P.3
-
153
-
-
36049034216
-
A single mutation in the PB1 F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence
-
Conenello GM, Zamarin D, Perrone LA, Tumpey T, Palese P: A single mutation in the PB1 F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence. PLoS Pathog. 3, 1414-1421 (2007).
-
(2007)
PLoS Pathog.
, vol.3
, pp. 1414-1421
-
-
Conenello, G.M.1
Zamarin, D.2
Perrone, L.A.3
Tumpey, T.4
Palese, P.5
-
154
-
-
34848926238
-
Expression of the 1918 influenza A virus PB1 F2 enhances the pathogenesis of viral and secondary bacterial pneumonia
-
McAuley JL, Hornung F, Boyd KL et al.: Expression of the 1918 influenza A virus PB1 F2 enhances the pathogenesis of viral and secondary bacterial pneumonia. Cell Host Microbe 2, 240-249 (2007).
-
(2007)
Cell Host Microbe
, vol.2
, pp. 240-249
-
-
McAuley, J.L.1
Hornung, F.2
Boyd, K.L.3
-
155
-
-
0029861191
-
Influenza virus neuraminidase activates latent transforming growth factor β
-
Schultz-Cherry S, Hinshaw VS: Influenza virus neuraminidase activates latent transforming growth factor β. J. Virol. 70, 8624-8629 (1996).
-
(1996)
J. Virol.
, vol.70
, pp. 8624-8629
-
-
Schultz-Cherry, S.1
Hinshaw, V.S.2
-
156
-
-
0032940423
-
Role of neuraminidase in influenza virus-induced apoptosis
-
Morris SJ, Price GE, Barnett JM, Hiscox SA, Smith H, Sweet C: Role of neuraminidase in influenza virus-induced apoptosis. J. Gen. Virol. 80 (Pt 1), 137-146 (1999).
-
(1999)
J. Gen. Virol.
, vol.80
, Issue.PT 1
, pp. 137-146
-
-
Morris, S.J.1
Price, G.E.2
Barnett, J.M.3
Hiscox, S.A.4
Smith, H.5
Sweet, C.6
-
157
-
-
0036558369
-
Interaction of influenza A virus M1 matrix protein with caspases
-
Zhirnov OP, Ksenofontov AL, Kuzmina SG, Klenk HD: Interaction of influenza A virus M1 matrix protein with caspases. Biochemistry (Mosc.) 67, 534-539 (2002).
-
(2002)
Biochemistry (Mosc.)
, vol.67
, pp. 534-539
-
-
Zhirnov, O.P.1
Ksenofontov, A.L.2
Kuzmina, S.G.3
Klenk, H.D.4
-
158
-
-
72649105081
-
Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes
-
Gannage M, Dormann D, Albrecht R et al.: Matrix protein 2 of influenza A virus blocks autophagosome fusion with lysosomes. Cell Host Microbe 6, 367-380 (2009).
-
(2009)
Cell Host Microbe
, vol.6
, pp. 367-380
-
-
Gannage, M.1
Dormann, D.2
Albrecht, R.3
-
159
-
-
65249090334
-
Autophagy is involved in influenza A virus replication
-
Zhou Z, Jiang X, Liu D et al.: Autophagy is involved in influenza A virus replication. Autophagy 5, 321-328 (2009).
-
(2009)
Autophagy
, vol.5
, pp. 321-328
-
-
Zhou, Z.1
Jiang, X.2
Liu, D.3
-
160
-
-
37549001315
-
The influenza virus NS1 protein: Inhibitor of innate and adaptive immunity
-
Fernandez-Sesma A: The influenza virus NS1 protein: inhibitor of innate and adaptive immunity. Infect. Disord. Drug Targets 7, 336-343 (2007).
-
(2007)
Infect. Disord. Drug Targets
, vol.7
, pp. 336-343
-
-
Fernandez-Sesma, A.1
-
161
-
-
55449088081
-
Interferon-b pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus
-
Phipps-Yonas H, Seto J, Sealfon SC, Moran TM, Fernandez-Sesma A: Interferon-b pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. PLoS Pathog. 4, e1000193 (2008).
-
(2008)
PLoS Pathog.
, vol.4
-
-
Phipps-Yonas, H.1
Seto, J.2
Sealfon, S.C.3
Moran, T.M.4
Fernandez-Sesma, A.5
-
162
-
-
58149196799
-
Antiviral-activated dendritic cells: A paracrine-induced response state
-
Borderia AV, Hartmann BM, Fernandez Sesma A, Moran TM, Sealfon SC: Antiviral-activated dendritic cells: a paracrine-induced response state. J. Immunol. 181, 6872-6881 (2008).
-
(2008)
J. Immunol.
, vol.181
, pp. 6872-6881
-
-
Borderia, A.V.1
Hartmann, B.M.2
Fernandez Sesma, A.3
Moran, T.M.4
Sealfon, S.C.5
-
163
-
-
0344642936
-
Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNA viruses
-
Lopez CB, Garcia-Sastre A, Williams BR, Moran TM: Type I interferon induction pathway, but not released interferon, participates in the maturation of dendritic cells induced by negative-strand RNA viruses. J. Infect. Dis. 187, 1126-1136 (2003).
-
(2003)
J. Infect. Dis.
, vol.187
, pp. 1126-1136
-
-
Lopez, C.B.1
Garcia-Sastre, A.2
Williams, B.R.3
Moran, T.M.4
-
164
-
-
67650113035
-
Preclinical evaluation of a replication-deficient intranasal DNS1 H5N1 influenza vaccine
-
Romanova J, Krenn BM, Wolschek M et al.: Preclinical evaluation of a replication-deficient intranasal DNS1 H5N1 influenza vaccine. PLoS ONE 4, e5984 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Romanova, J.1
Krenn, B.M.2
Wolschek, M.3
-
165
-
-
55249118428
-
Influenza B virus NS1-truncated mutants: Live-attenuated vaccine approach
-
Hai R, Martinez-Sobrido L, Fraser KA, Ayllon J, Garcia-Sastre A, Palese P: Influenza B virus NS1-truncated mutants: live-attenuated vaccine approach. J. Virol. 82, 10580-10590 (2008).
-
(2008)
J. Virol.
, vol.82
, pp. 10580-10590
-
-
Hai, R.1
Martinez-Sobrido, L.2
Fraser, K.A.3
Ayllon, J.4
Garcia-Sastre, A.5
Palese, P.6
-
166
-
-
64449083750
-
Development of a live-attenuated influenza B DNS1 intranasal vaccine candidate
-
Wressnigg N, Voss D, Wolff T et al.: Development of a live-attenuated influenza B DNS1 intranasal vaccine candidate. Vaccine 27, 2851-2857 (2009).
-
(2009)
Vaccine
, vol.27
, pp. 2851-2857
-
-
Wressnigg, N.1
Voss, D.2
Wolff, T.3
-
167
-
-
64749089192
-
CDC: Update: Influenza activity - United States, September 28, 2008-April 4, 2009, and composition of the 2009-2010 influenza vaccine
-
CDC: Update: influenza activity - United States, September 28, 2008-April 4, 2009, and composition of the 2009-2010 influenza vaccine. MMWR Morb. Mortal. Wkly Rep. 58, 369-374 (2009).
-
(2009)
MMWR Morb. Mortal. Wkly Rep.
, vol.58
, pp. 369-374
-
-
-
168
-
-
53749085251
-
Influenza A H5N1 clade 2.3.4 virus with a different antiviral susceptibility profile replaced clade 1 virus in humans in northern Vietnam
-
Le MT, Wertheim HF, Nguyen HD et al.: Influenza A H5N1 clade 2.3.4 virus with a different antiviral susceptibility profile replaced clade 1 virus in humans in northern Vietnam. PLoS ONE 3, e3339 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Le, M.T.1
Wertheim, H.F.2
Nguyen, H.D.3
-
169
-
-
27144468290
-
Avian flu: Isolation of drug-resistant H5N1 virus
-
Le QM, Kiso M, Someya K et al.: Avian flu: isolation of drug-resistant H5N1 virus. Nature 437, 1108 (2005).
-
(2005)
Nature
, vol.437
, pp. 1108
-
-
Le, Q.M.1
Kiso, M.2
Someya, K.3
-
170
-
-
69149093400
-
In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
-
Epub ahead of print
-
Itoh Y, Shinya K, Kiso M et al.: In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature (2009) (Epub ahead of print).
-
(2009)
Nature
-
-
Itoh, Y.1
Shinya, K.2
Kiso, M.3
-
171
-
-
65349186033
-
CDC: Update: Drug susceptibility of swine-origin influenza A (H1N1) viruses
-
April, 2009
-
CDC: Update: drug susceptibility of swine-origin influenza A (H1N1) viruses, April 2009. MMWR Morb. Mortal. Wkly Rep. 58, 433-435 (2009).
-
(2009)
MMWR Morb. Mortal. Wkly Rep.
, vol.58
, pp. 433-435
-
-
-
172
-
-
68649122631
-
Emerging antiviral targets for influenza A virus
-
Krug RM, Aramini JM: Emerging antiviral targets for influenza A virus. Trends Pharmacol. Sci. 30(6), 269-277 (2009).
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, Issue.6
, pp. 269-277
-
-
Krug, R.M.1
Aramini, J.M.2
-
173
-
-
53249140699
-
Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity
-
Hoffmann HH, Palese P, Shaw ML: Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity. Antiviral Res. 80, 124-134 (2008).
-
(2008)
Antiviral Res.
, vol.80
, pp. 124-134
-
-
Hoffmann, H.H.1
Palese, P.2
Shaw, M.L.3
-
174
-
-
67249156976
-
Targeting cell signalling pathways to fight the flu: Towards a paradigm change in anti-influenza therapy
-
Ludwig S: Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy. J. Antimicrob. Chemother. 64, 1-4 (2009).
-
(2009)
J. Antimicrob. Chemother.
, vol.64
, pp. 1-4
-
-
Ludwig, S.1
-
175
-
-
34248187720
-
Properties of H7N7 influenza A virus strain SC35M lacking interferon antagonist NS1 in mice and chickens
-
Kochs G, Koerner I, Thiel L et al.: Properties of H7N7 influenza A virus strain SC35M lacking interferon antagonist NS1 in mice and chickens. J. Gen. Virol. 88, 1403-1409 (2007).
-
(2007)
J. Gen. Virol.
, vol.88
, pp. 1403-1409
-
-
Kochs, G.1
Koerner, I.2
Thiel, L.3
-
176
-
-
33646478272
-
The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2́ 5́ oligo (A) synthetase/RNase L pathway
-
Min JY, Krug RM: The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2́ 5́ oligo (A) synthetase/RNase L pathway. Proc. Natl Acad. Sci. USA 103, 7100-7105 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 7100-7105
-
-
Min, J.Y.1
Krug, R.M.2
-
177
-
-
33749004778
-
Influenza a virus NS1 protein binds p85b and activates phosphatidylinositol- 3-kinase signaling
-
Hale BG, Jackson D, Chen YH, Lamb RA, Randall RE: Influenza A virus NS1 protein binds p85b and activates phosphatidylinositol- 3-kinase signaling. Proc. Natl Acad. Sci. USA 103, 14194-14199 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 14194-14199
-
-
Hale, B.G.1
Jackson, D.2
Chen, Y.H.3
Lamb, R.A.4
Randall, R.E.5
-
178
-
-
59649088815
-
Novel influenza virus NS1 antagonists block replication and restore innate immune function.
-
Basu D, Walkiewicz MP, Frieman M, Baric RS, Auble DT, Engel DA: Novel influenza virus NS1 antagonists block replication and restore innate immune function. J. Virol. 83, 1881-1891 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 1881-1891
-
-
Basu, D.1
Walkiewicz, M.P.2
Frieman, M.3
Baric, R.S.4
Auble, D.T.5
Engel, D.A.6
-
179
-
-
57749169511
-
X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus
-
Bornholdt ZA, Prasad BV: X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus. Nature 456, 985-988 (2008).
-
(2008)
Nature
, vol.456
, pp. 985-988
-
-
Bornholdt, Z.A.1
Prasad, B.V.2
-
180
-
-
33744925682
-
X-ray structure of influenza virus NS1 effector domain
-
Bornholdt ZA, Prasad BV: X-ray structure of influenza virus NS1 effector domain. Nat. Struct. Mol. Biol. 13, 559-560 (2006).
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 559-560
-
-
Bornholdt, Z.A.1
Prasad, B.V.2
-
181
-
-
47749143963
-
Structure of an avian influenza A virus NS1 protein effector domain
-
Hale BG, Barclay WS, Randall RE, Russell RJ: Structure of an avian influenza A virus NS1 protein effector domain. Virology 378, 1-5 (2008).
-
(2008)
Virology
, vol.378
, pp. 1-5
-
-
Hale, B.G.1
Barclay, W.S.2
Randall, R.E.3
Russell, R.J.4
-
182
-
-
0030710459
-
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein
-
Liu J, Lynch PA, Chien CY, Montelione GT, Krug RM, Berman HM: Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein. Nat. Struct. Biol. 4, 896-899 (1997).
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 896-899
-
-
Liu, J.1
Lynch, P.A.2
Chien, C.Y.3
Montelione, G.T.4
Krug, R.M.5
Berman, H.M.6
-
184
-
-
34547136235
-
Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses
-
Yin C, Khan JA, Swapna GV et al.: Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses. J. Biol. Chem. 282, 20584-20592 (2007).
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20584-20592
-
-
Yin, C.1
Khan, J.A.2
Swapna, G.V.3
-
185
-
-
59449110919
-
Structural basis for dsRNA recognition by NS1 protein of influenza A virus
-
Cheng A, Wong SM, Yuan YA: Structural basis for dsRNA recognition by NS1 protein of influenza A virus. Cell Res. 19, 187-195 (2009).
-
(2009)
Cell Res.
, vol.19
, pp. 187-195
-
-
Cheng, A.1
Wong, S.M.2
Yuan, Y.A.3
-
186
-
-
0030683491
-
A novel RNA-binding motif in influenza A virus non-structural protein 1
-
Chien CY, Tejero R, Huang Y et al.: A novel RNA-binding motif in influenza A virus non-structural protein 1. Nat. Struct. Biol. 4, 891-895 (1997).
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 891-895
-
-
Chien, C.Y.1
Tejero, R.2
Huang, Y.3
-
187
-
-
49249137457
-
Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein
-
Maroto M, Fernandez Y, Ortin J, Pelaez F, Cabello MA: Development of an HTS assay for the search of anti-influenza agents targeting the interaction of viral RNA with the NS1 protein. J. Biomol. Screen. 13, 581-590 (2008).
-
(2008)
J. Biomol. Screen.
, vol.13
, pp. 581-590
-
-
Maroto, M.1
Fernandez, Y.2
Ortin, J.3
Pelaez, F.4
Cabello, M.A.5
-
188
-
-
36749077601
-
An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis
-
Naito T, Kiyasu Y, Sugiyama K et al.: An influenza virus replicon system in yeast identified Tat-SF1 as a stimulatory host factor for viral RNA synthesis. Proc. Natl Acad. Sci. USA 104, 18235-18240 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 18235-18240
-
-
Naito, T.1
Kiyasu, Y.2
Sugiyama, K.3
-
189
-
-
49649127852
-
Drosophila RNAi screen identifies host genes important for influenza virus replication.
-
Hao L, Sakurai A, Watanabe T et al.: Drosophila RNAi screen identifies host genes important for influenza virus replication. Nature 454, 890-893 (2008).
-
(2008)
Nature
, vol.454
, pp. 890-893
-
-
Hao, L.1
Sakurai, A.2
Watanabe, T.3
-
191
-
-
75849152807
-
Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment
-
Epub ahead of print
-
Steel J, Staeheli P, Mubareka S, Garcia Sastre A, Palese P, Lowen AC: Transmission of pandemic H1N1 influenza virus and impact of prior exposure to seasonal strains or interferon treatment. J. Virol. (2009) (Epub ahead of print).
-
(2009)
J. Virol.
-
-
Steel, J.1
Staeheli, P.2
Mubareka, S.3
Garcia Sastre, A.4
Palese, P.5
Lowen, A.C.6
-
192
-
-
63149129764
-
A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant
-
Kobiyama K, Takeshita F, Ishii KJ et al.: A signaling polypeptide derived from an innate immune adaptor molecule can be harnessed as a new class of vaccine adjuvant. J. Immunol. 182, 1593-1601 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 1593-1601
-
-
Kobiyama, K.1
Takeshita, F.2
Ishii, K.J.3
-
193
-
-
59849117747
-
A TLR3 ligand that exhibits potent inhibition of influenza virus replication and has strong adjuvant activity has the potential for dual applications in an influenza pandemic
-
Lau YF, Tang LH, Ooi EE: A TLR3 ligand that exhibits potent inhibition of influenza virus replication and has strong adjuvant activity has the potential for dual applications in an influenza pandemic. Vaccine 27, 1354-1364 (2009).
-
(2009)
Vaccine
, vol.27
, pp. 1354-1364
-
-
Lau, Y.F.1
Tang, L.H.2
Ooi, E.E.3
-
194
-
-
38649127218
-
Clinical uses of interferons. Br
-
Friedman RM: Clinical uses of interferons. Br. J. Clin. Pharmacol. 65, 158-162 (2008).
-
(2008)
J. Clin. Pharmacol.
, vol.65
, pp. 158-162
-
-
Friedman, R.M.1
-
195
-
-
33847214535
-
NS1 proteins of avian influenza A viruses can act as antagonists of the human α/β interferon response
-
Hayman A, Comely S, Lackenby A et al.: NS1 proteins of avian influenza A viruses can act as antagonists of the human α/β interferon response. J. Virol. 81, 2318-2327 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 2318-2327
-
-
Hayman, A.1
Comely, S.2
Lackenby, A.3
-
196
-
-
48249157351
-
Domestic pigs have low susceptibility to H5N1 highly pathogenic avian influenza viruses
-
Lipatov AS, Kwon YK, Sarmento LV et al.: Domestic pigs have low susceptibility to H5N1 highly pathogenic avian influenza viruses. PLoS Pathog. 4, e1000102 (2008).
-
(2008)
PLoS Pathog
, vol.4
-
-
Lipatov, A.S.1
Kwon, Y.K.2
Sarmento, L.V.3
-
197
-
-
66149098818
-
Experimental infection of pigs with the human 1918 pandemic influenza virus
-
Weingartl HM, Albrecht RA, Lager KM et al.: Experimental infection of pigs with the human 1918 pandemic influenza virus. J. Virol. 83, 4287-4296 (2009).
-
(2009)
J. Virol.
, vol.83
, pp. 4287-4296
-
-
Weingartl, H.M.1
Albrecht, R.A.2
Lager, K.M.3
-
198
-
-
26444490055
-
Characterization of the reconstructed 1918 Spanish influenza pandemic virus
-
Tumpey TM, Basler CF, Aguilar PV et al.: Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 310, 77-80 (2005).
-
(2005)
Science
, vol.310
, pp. 77-80
-
-
Tumpey, T.M.1
Basler, C.F.2
Aguilar, P.V.3
-
199
-
-
33846820412
-
A two-amino acid change in the hemagglutinin of the 1918. influenza virus abolishes transmission
-
Tumpey TM, Maines TR, Van Hoeven N et al.: A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. Science 315, 655-659 (2007).
-
(2007)
Science
, vol.315
, pp. 655-659
-
-
Tumpey, T.M.1
Maines, T.R.2
Van Hoeven, N.3
-
201
-
-
33645765519
-
Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection
-
Malakhov MP, Aschenbrenner LM, Smee DF et al.: Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection. Antimicrob. Agents Chemother. 50, 1470-1479 (2006).
-
(2006)
Antimicrob. Agents Chemother.
, vol.50
, pp. 1470-1479
-
-
Malakhov, M.P.1
Aschenbrenner, L.M.2
Smee, D.F.3
-
202
-
-
38449093101
-
DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection
-
Belser JA, Lu X, Szretter KJ et al.: DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection. J. Infect. Dis. 196, 1493-1499 (2007).
-
(2007)
J. Infect. Dis.
, vol.196
, pp. 1493-1499
-
-
Belser, J.A.1
Lu, X.2
Szretter, K.J.3
-
203
-
-
33750362127
-
An integrated molecular signature of disease: Analysis of influenza virus-infected macaques through functional genomics and proteomics
-
Baas T, Baskin CR, Diamond DL et al.: An integrated molecular signature of disease: analysis of influenza virus-infected macaques through functional genomics and proteomics. J. Virol. 80(21), 10813-10828 (2006).
-
(2006)
J. Virol.
, vol.80
, Issue.21
, pp. 10813-10828
-
-
Baas, T.1
Baskin, C.R.2
Diamond, D.L.3
-
204
-
-
34447263302
-
Peptide-mediated interference with influenza A virus polymerase
-
Ghanem A, Mayer D, Chase G et al.: Peptide-mediated interference with influenza A virus polymerase. J. Virol. 81, 7801-7804 (2007).
-
(2007)
J. Virol.
, vol.81
, pp. 7801-7804
-
-
Ghanem, A.1
Mayer, D.2
Chase, G.3
-
205
-
-
64749093901
-
T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections
-
Furuta Y, Takahashi K, Shiraki K et al.: T-705 (favipiravir) and related compounds: novel broad-spectrum inhibitors of RNA viral infections. Antiviral Res. 82, 95-102 (2009).
-
(2009)
Antiviral Res.
, vol.82
, pp. 95-102
-
-
Furuta, Y.1
Takahashi, K.2
Shiraki, K.3
|