Efp targets 14-3-3± for proteolysis and promotes breast tumour growth

Nature

Volumn 417, Issue 6891, 2002, Pages 871-876

  Urano, Tomohiko ^a   Saito, Tomoyuki ^a,d   Tsukui, Tohru ^b   Fujita, Masayo ^a   Hosoi, Takayuki ^a   Muramatsu, Masami ^b   Ouchi, Yasuyoshi ^a   Inoue, Satoshi ^a,b,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b SAITAMA MEDICAL UNIVERSITY   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d Grelan Pharmaceutical Co   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; GENES; TUMORS;

PROTEOLYSIS;

GENETIC ENGINEERING;

ESTROGEN; ESTROGEN RECEPTOR; GENE PRODUCT; PROTEIN; PROTEIN 14 3 3; PROTEIN EFP; PROTEIN RBCC; UBIQUITIN; UNCLASSIFIED DRUG;

MEDICINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; BREAST TUMOR; CARCINOGENESIS; CELL CYCLE G2 PHASE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; GENE OVEREXPRESSION; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; TUMOR GROWTH;

ANIMALS; BREAST NEOPLASMS; CELL CYCLE; CELL DIVISION; COS CELLS; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; ESTROGENS; EXONUCLEASES; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, NEOPLASTIC; LIGASES; MICE; MICE, INBRED BALB C; MICE, NUDE; MULTIENZYME COMPLEXES; NEOPLASM PROTEINS; NEOPLASM TRANSPLANTATION; PRECIPITIN TESTS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEINS; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; MUS MUSCULUS;

EID: 0037142070     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00826     Document Type: Article

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