Conserved surface features form the double-stranded RNA binding site of non-structural protein 1 (NS1) from influenza A and B viruses

Journal of Biological Chemistry

Volumn 282, Issue 28, 2007, Pages 20584-20592

  Yin, Cuifeng ^a   Khan, Javed A ^b   Swapna, G V T ^a   Ertekin, Asli ^a,d   Krug, Robert M ^c   Tong, Liang ^b   Montelione, Gaetano T ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^d RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRAL DRUGS; DSRNA; HOMODIMERS;

BINDING SITES; DRUG PRODUCTS; MUTAGENESIS; NUCLEAR MAGNETIC RESONANCE; PROTEINS; PULMONARY DISEASES; VIRUSES;

RNA;

DOUBLE STRANDED RNA; EPITOPE; NONSTRUCTURAL PROTEIN 1; POLYPHOSPHATE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME CONFORMATION; GENE INTERACTION; GENE TARGETING; HYDROPHILICITY; HYDROPHOBICITY; INFLUENZA VIRUS A; INFLUENZA VIRUS B; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN RNA BINDING; RNA STRUCTURE; VIRUS REPLICATION; VIRUS VIRULENCE; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; INFLUENZA A VIRUS; INFLUENZA B VIRUS; INFLUENZA, HUMAN; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; NUCLEIC ACID CONFORMATION; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RNA, DOUBLE-STRANDED; RNA, VIRAL; VIRAL NONSTRUCTURAL PROTEINS;

CERCOPITHECINE HERPESVIRUS 1; INFLUENZA A VIRUS; INFLUENZA B VIRUS;

EID: 34547136235     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611619200     Document Type: Article

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