Early and sustained innate immune response defines pathology and death in nonhuman primates infected by highly pathogenic influenza virus

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 9, 2009, Pages 3455-3460

  Baskin, Carole R ^a,b   Bielefeldt Ohmann, Helle ^c   Tumpey, Terrence M ^d   Sabourin, Patrick J ^e   Long, James P ^e   García Sastre, Adolfo ^f   Tolnay, Airn E ^c   Albrecht, Randy ^f   Pyles, John A ^e   Olson, Pam H ^e   Aicher, Lauri D ^a   Rosenzweig, Elizabeth R ^a   Murali Krishna, Kaja ^a   Clark, Edward A ^a   Kotur, Mark S ^e   Fornek, Jamie L ^a   Proll, Sean ^a   Palermo, Robert E ^a   Sabourin, Carol L ^e   Katzea, Michael G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c Veterinary Dentistry and Oral Surgery   (United States)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^e BATTELLE MEMORIAL INSTITUTE   (United States)

^f MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

1918 pandemic; Functional genomics; H5N1

Indexed keywords

HEMAGGLUTININ; INTERFERON; NONSTRUCTURAL PROTEIN 1; SIALIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; DENDRITIC CELL; FEMALE; GENOMICS; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS A H5N1; INNATE IMMUNITY; LUNG ALVEOLUS CELL; LUNG PARENCHYMA; LYMPH NODE; MACACA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; T LYMPHOCYTE; TISSUE GROWTH; VIRUS VIRULENCE;

ANIMALS; CELL MOVEMENT; DENDRITIC CELLS; GENE EXPRESSION PROFILING; HUMANS; IMMUNITY, INNATE; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; LUNG DISEASES; LYMPH NODES; MACACA; MALE; ORTHOMYXOVIRIDAE INFECTIONS; SURVIVAL RATE; T-LYMPHOCYTES; TIME FACTORS; TROPISM; VIRUS REPLICATION;

AVES; MACACA; MACACA FASCICULARIS; ORTHOMYXOVIRIDAE; PRIMATES;

EID: 62549085229     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0813234106     Document Type: Article

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