Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 38, 2006, Pages 14194-14199

  Hale, Benjamin G ^a   Jackson, David ^b   Chen, Yun Hsiang ^a   Lamb, Robert A ^b   Randall, Richard E ^a  

^a UNIVERSITY OF ST ANDREWS   (United Kingdom)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Akt phosphorylation; Multifunctional; NS1 protein; Reverse genetics

Indexed keywords

AMINO ACID; INFLUENZA A VIRUS NS1 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P85; PROTEIN P85BETA; PROTEIN SH2; TYROSINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CORRELATION ANALYSIS; CULTURE MEDIUM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE REPLICATION; HUMAN; HUMAN CELL; INFLUENZA; INFLUENZA VIRUS A; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TISSUE CULTURE; VIRAL GENETICS; VIRUS CELL INTERACTION; VIRUS CULTURE; VIRUS GENOME;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACID SUBSTITUTION; ANIMALS; CELL LINE; ENZYME ACTIVATION; HUMANS; INFLUENZAVIRUS A; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TYROSINE; VIRAL NONSTRUCTURAL PROTEINS;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE;

EID: 33749004778     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0606109103     Document Type: Article

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