Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

Nature Medicine

Volumn 12, Issue 10, 2006, Pages 1203-1207

  De Jong, Menno D ^a   Simmons, Cameron P ^a   Thanh, Tran Tan ^a   Hien, Vo Minh ^b   Smith, Gavin J D ^c   Chau, Tran Nguyen Bich ^a   Hoang, Dang Minh ^a   Chau, Nguyen Van Vinh ^b   Khanh, Truong Huu ^d   Dong, Vo Cong ^d   Qui, Phan Tu ^d   Cam, Bach Van ^d   Ha, Do Quang ^a   Guan, Yi ^c   Peiris, J S Malik ^c   Chinh, Nguyen Tran ^b   Hien, Tran Tinh ^b   Farrar, Jeremy ^a  

^a OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^c THE UNIVERSITY OF HONG KONG   (Hong Kong)

^d Pediatric Hospital Number One   (Viet Nam)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; VIRUS RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FATALITY; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; INFLUENZA VIRUS; INFLUENZA VIRUS A H5N1; LYMPHOCYTE COUNT; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; RNA ANALYSIS; SEQUENCE ANALYSIS; T LYMPHOCYTE; THROAT CULTURE; VIRUS CHARACTERIZATION; VIRUS LOAD; VIRUS STRAIN; VIRUS VIRULENCE;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CYTOKINES; FLOW CYTOMETRY; HUMANS; INFANT; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA, HUMAN; MIDDLE AGED; MOLECULAR SEQUENCE DATA; RNA, VIRAL; T-LYMPHOCYTES; TREATMENT OUTCOME;

ANIMALIA; AVES; HUMAN INFLUENZA VIRUS; INFLUENZA A VIRUS; MAMMALIA;

EID: 33749511112     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1477     Document Type: Article

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