The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways

Journal of Virology

Volumn 83, Issue 20, 2009, Pages 10557-10570

  Billharz, Rosalind ^a   Zeng, Hui ^b   Proll, Sean C ^a   Korth, Marcus J ^a   Lederer, Sharon ^a   Albrecht, Randy ^c   Goodman, Alan G ^a   Rosenzweig, Elizabeth ^a   Tumpey, Terrence M ^b   García Sastre, Adolfo ^c   Katze, Michael G ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

^b NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; INTERFERON; LIPID; NONSTRUCTURAL PROTEIN 1;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL INFILTRATION; DOWN REGULATION; FUNCTIONAL GENOMICS; GENE DISRUPTION; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC REASSORTMENT; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INFLUENZA; INFLUENZA VIRUS; INNATE IMMUNITY; LIPID METABOLISM; LUNG ALVEOLUS EPITHELIUM; LUNG INFECTION; NONHUMAN; PANDEMIC; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPANISH INFLUENZA; VIRUS INHIBITION; VIRUS REPLICATION; VIRUS VIRULENCE;

CELL LINE; DISEASE OUTBREAKS; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTERFERONS; LIPID METABOLISM; LUNG; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PLAQUE ASSAY; PROTEINS; RECOMBINANT FUSION PROTEINS; VIRAL NONSTRUCTURAL PROTEINS;

HUMAN INFLUENZA VIRUS; ORTHOMYXOVIRIDAE;

EID: 70349737879     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00330-09     Document Type: Article

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