Novel influenza virus NS1 antagonists block replication and restore innate immune function

Journal of Virology

Volumn 83, Issue 4, 2009, Pages 1881-1891

  Basu, Dipanwita ^a   Walkiewicz, Marcin P ^a   Frieman, Matthew ^b   Baric, Ralph S ^b   Auble, David T ^a   Engel, Daniel A ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b IL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BETA INTERFERON; DOUBLE STRANDED RNA; INTERFERON; MESSENGER RNA; NONSTRUCTURAL PROTEIN 1; NSC 109834; NSC 125044; NSC 128164; NSC 95676; PAPAINLIKE PROTEASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CORONAVIRUS; DRUG MECHANISM; EMBRYO; GENE ACTIVATION; GENE INDUCTION; HOST; HUMAN; HUMAN CELL; IC 50; INFLUENZA VIRUS; INFLUENZA VIRUS A; INNATE IMMUNITY; MOBILIZATION; MOLECULAR PROBE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FUNCTION; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRUS CELL INTERACTION; VIRUS CULTURE; VIRUS INFECTION; VIRUS REPLICATION; VIRUS RESISTANCE; YEAST;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; HUMANS; INFLUENZA A VIRUS; INTERFERON-BETA; RESPIRATORY SYNCYTIAL VIRUSES; SARS VIRUS; VIRAL NONSTRUCTURAL PROTEINS; VIRUS REPLICATION;

INFLUENZA A VIRUS; ORTHOMYXOVIRIDAE; RESPIRATORY SYNCYTIAL VIRUS; RNA VIRUSES; SARS CORONAVIRUS;

EID: 59649088815     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01805-08     Document Type: Article

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