Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA

Virology

Volumn 349, Issue 1, 2006, Pages 13-21

  Li, Shoudong ^a,b   Min, Ji Young ^c   Krug, Robert M ^c   Sen, Ganes C ^a,b  

^a LERNER RESEARCH INSTITUTE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Double stranded RNA; Influenza virus; Interferon action; PACT; PKR; Viral evasion

Indexed keywords

DOUBLE STRANDED RNA; INITIATION FACTOR 2ALPHA; NONSTRUCTURAL PROTEIN 1A; PROTEIN; PROTEIN KINASE R; PROTEIN PACT; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLUENZA VIRUS A; INNATE IMMUNITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA BINDING; VIRUS VIRULENCE; WILD TYPE;

APOPTOSIS; CELL LINE; EIF-2 KINASE; ENZYME ACTIVATION; EUKARYOTIC INITIATION FACTOR-2; HUMANS; INFLUENZA A VIRUS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; RNA; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; VIRAL NONSTRUCTURAL PROTEINS;

INFLUENZA A VIRUS; INFLUENZAVIRUS A; ORTHOMYXOVIRIDAE;

EID: 33646517711     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.01.005     Document Type: Article

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