TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

Nature

Volumn 446, Issue 7138, 2007, Pages 916-920

  Gack, Michaela U ^a,b   Shin, Young C ^a   Joo, Chul Hyun ^a,c   Urano, Tomohiko ^d,e   Liang, Chengyu ^a   Sun, Lijun ^f   Takeuchi, Osamu ^g   Akira, Shizuo ^g   Chen, Zhijian ^f   Inoue, Satoshi ^d,e   Jung, Jae U ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c University of Ulsan College of Medicine   (South Korea)

^d UNIVERSITY OF TOKYO   (Japan)

^e SAITAMA MEDICAL UNIVERSITY   (Japan)

^f UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; PROTEIN TRIM25; RETINOIC ACID INDUCIBLE GENE 1 PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRUS RECEPTOR;

ENZYME ACTIVITY; GENE; IMMUNITY; INFECTIOUS DISEASE; PROTEIN; VIRAL DISEASE; VIRUS;

AMINO TERMINAL SEQUENCE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EMBRYO; GENE TARGETING; HUMAN; HUMAN CELL; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; VIRUS INFECTION;

MAMMALIA; RNA VIRUSES;

EID: 34247341367     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05732     Document Type: Article

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