Efficacy of intranasal administration of a truncated NS1 modified live influenza virus vaccine in swine

Vaccine

Volumn 25, Issue 47, 2007, Pages 7999-8009

  Vincent, Amy L ^a   Ma, Wenjun ^a,b   Lager, Kelly M ^a   Janke, Bruce H ^b   Webby, Richard J ^c   García Sastre, Adolfo ^d   Richt, Jürgen A ^a  

^a NATIONAL ANIMAL DISEASE CENTER   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Het I; Influenza A; Modified live virus vaccine; Swine influenza virus

Indexed keywords

INFLUENZA VACCINE; LIVE VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CROSS REACTION; DOSE RESPONSE; DRUG EFFICACY; FEVER; GENE EXPRESSION; HEMAGGLUTINATION INHIBITION TEST; INFECTION PREVENTION; INFLUENZA; INFLUENZA VACCINATION; LUNG INJURY; NONHUMAN; PRIORITY JOURNAL; SWINE; SWINE INFLUENZA VIRUS; VIRUS STRAIN; WILD TYPE;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTIBODIES, VIRAL; BODY TEMPERATURE; CROSS REACTIONS; GENOME, VIRAL; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA VACCINES; INJECTIONS, INTRAMUSCULAR; ORTHOMYXOVIRIDAE INFECTIONS; PNEUMONIA; SWINE DISEASES; VACCINES, ATTENUATED; VIRAL NONSTRUCTURAL PROTEINS;

EID: 35548976678     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.09.019     Document Type: Article

References (49)

1. Belshe R.B. Current status of live attenuated influenza virus vaccine in the US. Virus Res 103 1/2 (2004) 177-185
2. Townsend H.G., Penner S.J., Watts T.C., Cook A., Bogdan J., Haines D.M., et al. Efficacy of a cold-adapted, intranasal, equine influenza vaccine: challenge trials. Equine Vet J 33 7 (2001) 637-643
3. Belshe R.B., Nichol K.L., Black S.B., Shinefield H., Cordova J., Walker R., et al. Safety, efficacy, and effectiveness of live, attenuated, cold-adapted influenza vaccine in an indicated population aged 5-49 years. Clin Infect Dis 39 7 (2004) 920-927
4. Buonagurio D.A., O'Neill R.E., Shutyak L., D'Arco G.A., Bechert T.M., Kazachkov Y., et al. Genetic and phenotypic stability of cold-adapted influenza viruses in a trivalent vaccine administered to children in a day care setting. Virology 347 2 (2006) 296-306
5. Chambers T.M., Holland R.E., Tudor L.R., Townsend H.G., Cook A., Bogdan J., et al. A new modified live equine influenza virus vaccine: phenotypic stability, restricted spread and efficacy against heterologous virus challenge. Equine Vet J 33 7 (2001) 630-636
6. Vesikari T., Karvonen A., Korhonen T., Edelman K., Vainionpaa R., Salmi A., et al. A randomized, double-blind study of the safety, transmissibility and phenotypic and genotypic stability of cold-adapted influenza virus vaccine. Pediatr Infect Dis J 25 7 (2006) 590-595
7. Solorzano A., Webby R.J., Lager K.M., Janke B.H., Garcia-Sastre A., and Richt J.A. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J Virol 79 12 (2005) 7535-7543
8. Richt J.A., Lekcharoensuk P., Lager K.M., Vincent A.L., Loiacono C.M., Janke B.H., et al. Vaccination of pigs against swine influenza viruses using a NS1-truncated modified live virus vaccine. J Virol 80 22 (2006) 11009-11018
9. Vincent A.L., Lager K.M., Ma W., Lekcharoensuk P., Gramer M.R., Loiacono C., et al. Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States. Vet Microbiol 118 (2006) 212-222
10. Webby R.J., Rossow K., Erickson G., Sims Y., and Webster R. Multiple lineages of antigenically and genetically diverse influenza A virus co-circulate in the United States swine population. Virus Res 103 1/2 (2004) 67-73
11. Choi Y.K., Goyal S.M., and Joo H.S. Prevalence of swine influenza virus subtypes on swine farms in the United States. Arch Virol 147 6 (2002) 1209-1220
12. Easterday B.C., and Reeth K.V. Swine influenza. In: Straw B.E., D'Allaire S., Mengeling W.L., and Taylor D.J. (Eds). Diseases of swine. 8th ed. (1999), Iowa State University Press, Ames 277-290
13. Zhou N.N., Senne D.A., Landgraf J.S., Swenson S.L., Erickson G., Rossow K., et al. Genetic reassortment of avian, swine, and human influenza A viruses in American pigs. J Virol 73 10 (1999) 8851-8856
14. Zhou N.N., Senne D.A., Landgraf J.S., Swenson S.L., Erickson G., Rossow K., et al. Emergence of H3N2 reassortant influenza A viruses in North American pigs. Vet Microbiol 74 1/2 (2000) 47-58
15. Gramer M.R. Reassortant human/swine H1N1 and H1N2 influenza virus infections in US swine. Proceedings of the 37th Annual Meeting of the American Association of Swine Veterinarians. Kansas City, Missouri, March 4-7, 2006 (2006) 463-464
16. Janke B.H., Harmon K.M., Yoon K.J., Erickson G.A., and Webby R.J. Relative prevalence of reassortant H1N1 swine influenza viruses with avian polymerase genes and classic H1N1 viruses with swine polymerase genes. Proceedings of the 47th Annual Conference of the American Association of Veterinary Laboratory Diagnosticians. Greensboro, NC, October 15-21, 2004 (2004) 146
17. Karasin A.I., Landgraf J., Swenson S., Erickson G., Goyal S., Woodruff M., et al. Genetic characterization of H1N2 influenza A viruses isolated from pigs throughout the United States. J Clin Microbiol 40 3 (2002) 1073-1079
18. Gramer M.R. SIV: an update on circulating strains advances in diagnostic tests and interpretation of test results. Proceedings of the 38th Annual Meeting of the American Association of Swine Veterinarians. Orlando, FL, March 3-6, 2007 (2007)
19. Karasin A.I., Carman S., and Olsen C.W. Identification of human H1N2 and human-swine reassortant H1N2 and H1N1 influenza A viruses among pigs in Ontario, Canada (2003 to 2005). J Clin Microbiol 44 3 (2006) 1123-1126
20. Epstein S.L., Lo C.Y., Misplon J.A., Lawson C.M., Hendrickson B.A., Max E.E., et al. Mechanisms of heterosubtypic immunity to lethal influenza A virus infection in fully immunocompetent, T cell-depleted, beta2-microglobulin-deficient, and J chain-deficient mice. J Immunol 158 3 (1997) 1222-1230
21. Mozdzanowska K., Furchner M., Washko G., Mozdzanowski J., and Gerhard W. A pulmonary influenza virus infection in SCID mice can be cured by treatment with hemagglutinin-specific antibodies that display very low virus-neutralizing activity in vitro. J Virol 71 6 (1997) 4347-4355
22. Mozdzanowska K., Maiese K., Furchner M., and Gerhard W. Treatment of influenza virus-infected SCID mice with nonneutralizing antibodies specific for the transmembrane proteins matrix 2 and neuraminidase reduces the pulmonary virus titer but fails to clear the infection. Virology 254 1 (1999) 138-146
23. Tumpey T.M., Renshaw M., Clements J.D., and Katz J.M. Mucosal delivery of inactivated influenza vaccine induces B-cell-dependent heterosubtypic cross-protection against lethal influenza A H5N1 virus infection. J Virol 75 11 (2001) 5141-5150
24. Thomas P.G., Keating R., Hulse-Post D.J., and Doherty P.C. Cell-mediated protection in influenza infection. Emerg Infect Dis 12 1 (2006) 48-54
25. Richt J.A., Lager K.M., Janke B.H., Woods R.D., Webster R.G., and Webby R.J. Pathogenic and antigenic properties of phylogenetically distinct reassortant H3N2 swine influenza viruses cocirculating in the United States. J Clin Microbiol 41 7 (2003) 3198-3205
26. Kitikoon P., Nilubol D., Erickson B.J., Janke B.H., Hoover T., Sornsen S., et al. The immune response and maternal antibody interference to a heterologous H1N1 swine influenza virus infection following vaccination. Vet Immunol Immunopathol 112 3-4 (2006) 117-128
27. Reed L.J., and Muench H. A simple method of estimating fifty percent endpoints. Am J Hyg 27 (1938) 493-497
28. Halbur P.G., Paul P.S., Frey M.L., Landgraf J., Eernisse K., Meng X.J., et al. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet Pathol 32 6 (1995) 648-660
29. Palmer D.F., Coleman M.T., Dowdle W.R., and Schild G.C. Advanced laboratory techniques for influenza diagnosis (1975), U.S. Department of Health, Education, and Welfare, Washington, DC
30. Larsen D.L., Karasin A., Zuckermann F., and Olsen C.W. Systemic and mucosal immune responses to H1N1 influenza virus infection in pigs. Vet Microbiol 74 1/2 (2000) 117-131
31. Garcia-Sastre A., Egorov A., Matassov D., Brandt S., Levy D.E., Durbin J.E., et al. Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems. Virology 252 2 (1998) 324-330
32. Wang X., Basler C.F., Williams B.R., Silverman R.H., Palese P., and Garcia-Sastre A. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. J Virol 76 24 (2002) 12951-12962
33. Wang X., Li M., Zheng H., Muster T., Palese P., Beg A.A., et al. Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon. J Virol 74 24 (2000) 11566-11573
34. Pichlmair A., Schulz O., Tan C.P., Naslund T.I., Liljestrom P., Weber F., et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314 5801 (2006) 997-1001
35. Liew F.Y., Russell S.M., Appleyard G., Brand C.M., and Beale J. Cross-protection in mice infected with influenza A virus by the respiratory route is correlated with local IgA antibody rather than serum antibody or cytotoxic T cell reactivity. Eur J Immunol 14 4 (1984) 350-356
36. Schulman J.L., and Kilbourne E.D. Induction of partial specific heterotypic immunity in mice by a single infection with influenza a virus. J Bacteriol 89 (1965) 170-174
37. Van Reeth K.V., Brown I., Essen S., and Pensaert M. Genetic relationships, serological cross-reaction and cross-protection between H1N2 and other influenza A virus subtypes endemic in European pigs. Virus Res 103 1/2 (2004) 115-124
38. Webster R.G., and Askonas B.A. Cross-protection and cross-reactive cytotoxic T cells induced by influenza virus vaccines in mice. Eur J Immunol 10 5 (1980) 396-401
39. Tamura S., Funato H., Hirabayashi Y., Suzuki Y., Nagamine T., Aizawa C., et al. Cross-protection against influenza A virus infection by passively transferred respiratory tract IgA antibodies to different hemagglutinin molecules. Eur J Immunol 21 6 (1991) 1337-1344
40. Renegar K.B., and Small Jr. P.A. Immunoglobulin A mediation of murine nasal anti-influenza virus immunity. J Virol 65 4 (1991) 2146-2148
41. Kim W.I., Wu W.H., Janke B., and Yoon K.J. Characterization of the humoral immune response of experimentally infected and vaccinated pigs to swine influenza viral proteins. Arch Virol 151 1 (2006) 23-36
42. Flynn K.J., Riberdy J.M., Christensen J.P., Altman J.D., and Doherty P.C. In vivo proliferation of naive and memory influenza-specific CD8(+) T cells. Proc Natl Acad Sci USA 96 15 (1999) 8597-8602
43. Scherle P.A., and Gerhard W. Functional analysis of influenza-specific helper T cell clones in vivo. T cells specific for internal viral proteins provide cognate help for B cell responses to hemagglutinin. J Exp Med 164 4 (1986) 1114-1128
44. Taylor P.M., and Askonas B.A. Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo. Immunology 58 3 (1986) 417-420
45. Ulmer J.B., Donnelly J.J., Parker S.E., Rhodes G.H., Felgner P.L., Dwarki V.J., et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259 5102 (1993) 1745-1749
46. Choi Y.K., Goyal S.M., Farnham M.W., and Joo H.S. Phylogenetic analysis of H1N2 isolates of influenza A virus from pigs in the United States. Virus Res 87 2 (2002) 173-179
47. Gorman O.T., Bean W.J., Kawaoka Y., Donatelli I., Guo Y.J., and Webster R.G. Evolution of influenza A virus nucleoprotein genes: implications for the origins of H1N1 human and classical swine viruses. J Virol 65 7 (1991) 3704-3714
48. Ito T., Gorman O.T., Kawaoka Y., Bean W.J., and Webster R.G. Evolutionary analysis of the influenza A virus M gene with comparison of the M1 and M2 proteins. J Virol 65 10 (1991) 5491-5498
49. Tamura S., Tanimoto T., and Kurata T. Mechanisms of broad cross-protection provided by influenza virus infection and their application to vaccines. Jpn J Infect Dis 58 4 (2005) 195-207