Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA

Science

Volumn 303, Issue 5663, 2004, Pages 1529-1531

  Diebold, Sandra S ^a   Kaisho, Tsuneyasu ^b,c   Hemmi, Hiroaki ^b   Akira, Shizuo ^b,d   Reis E Sousa, Caetano ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b OSAKA UNIVERSITY   (Japan)

^c RIKEN   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; GENES; GENETIC ENGINEERING; RNA; VIRUSES;

IMMUNE SYSTEMS; VIRAL INFECTIONS;

INTERFERONS;

ALPHA INTERFERON; GENOMIC RNA; LIGAND; MYELOID DIFFERENTIATION FACTOR 88; RNA; SINGLE STRANDED RNA; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG;

IMMUNE RESPONSE; RNA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; ENDOSOME; IMMUNE SYSTEM; INFLUENZA VIRUS; MOUSE; NONHUMAN; PRIORITY JOURNAL; VIRUS DETECTION; VIRUS INFECTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; DENDRITIC CELLS; ENDOCYTOSIS; ENDOSOMES; GENOME, VIRAL; IMMUNITY, NATURAL; INFLUENZA A VIRUS; INTERFERON-ALPHA; LIGANDS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MYELOID DIFFERENTIATION FACTOR 88; POLY U; POLYRIBONUCLEOTIDES; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RNA; RNA, VIRAL; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 7;

ANIMALIA; INFLUENZA VIRUS; RNA VIRUSES;

EID: 1542317550     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1093616     Document Type: Article

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