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Volumn 81, Issue 21, 2007, Pages 11817-11827

Functional genomic and serological analysis of the protective immune response resulting from vaccination of macaques with an NS1-truncated influenza virus

Author keywords

[No Author keywords available]

Indexed keywords

FORMALDEHYDE; IMMUNOGLOBULIN G; INFLUENZA VACCINE; INTERFERON; NONSTRUCTURAL PROTEIN 1; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 35448980010     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00590-07     Document Type: Article
Times cited : (78)

References (52)
  • 1
    • 0033838456 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus
    • Aragon, T., S. de la Luna, I. Novoa, L. Carrasco, J. Ortin, and A. Nieto. 2000. Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol. Cell. Biol. 20:6259-6268.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 6259-6268
    • Aragon, T.1    de la Luna, S.2    Novoa, I.3    Carrasco, L.4    Ortin, J.5    Nieto, A.6
  • 3
    • 18844389483 scopus 로고    scopus 로고
    • Influenza vaccines: Recent advances in production technologies
    • Bardiya, N., and J. H. Bae. 2005. Influenza vaccines: recent advances in production technologies. Appl. Microbiol. Biotechnol. 67:299-305.
    • (2005) Appl. Microbiol. Biotechnol , vol.67 , pp. 299-305
    • Bardiya, N.1    Bae, J.H.2
  • 4
    • 4544271953 scopus 로고    scopus 로고
    • Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina)
    • Baskin, C. R., A. Garcia-Sastre, T. M. Tumpey, H. Bielefeldt-Ohmann, V. S. Carter, E. Nistal-Villan, and M. G. Katze. 2004. Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina). J. Virol. 78:10420-10432.
    • (2004) J. Virol , vol.78 , pp. 10420-10432
    • Baskin, C.R.1    Garcia-Sastre, A.2    Tumpey, T.M.3    Bielefeldt-Ohmann, H.4    Carter, V.S.5    Nistal-Villan, E.6    Katze, M.G.7
  • 5
    • 0036628966 scopus 로고    scopus 로고
    • Viruses and the type I interferon antiviral system: Induction and evasion
    • Basler, C. F., and A. Garcia-Sastre. 2002. Viruses and the type I interferon antiviral system: induction and evasion. Int. Rev. Immunol. 21:305-337.
    • (2002) Int. Rev. Immunol , vol.21 , pp. 305-337
    • Basler, C.F.1    Garcia-Sastre, A.2
  • 8
    • 0025913014 scopus 로고
    • Cytokine synergy with viral cytopathic effects and bacterial products during the pathogenesis of respiratory tract infection
    • Bielefeldt-Ohmann, H., L. A. Babiuk, and R. Harland. 1991. Cytokine synergy with viral cytopathic effects and bacterial products during the pathogenesis of respiratory tract infection. Clin. Immunol. Immunopathol. 60:153-170.
    • (1991) Clin. Immunol. Immunopathol , vol.60 , pp. 153-170
    • Bielefeldt-Ohmann, H.1    Babiuk, L.A.2    Harland, R.3
  • 10
    • 3042542202 scopus 로고    scopus 로고
    • Report on the thirteenth international workshop on the identification and functional, evolutionary and expression analysis of transcribed sequences: Comparative and functional genomics workshop
    • Brazma, A., T. Freeman, K. Gardiner, S. Weissman, T. Werner, and B. Korn. 2004. Report on the thirteenth international workshop on the identification and functional, evolutionary and expression analysis of transcribed sequences: comparative and functional genomics workshop. Cytogenet. Genome Res. 105:11-17.
    • (2004) Cytogenet. Genome Res , vol.105 , pp. 11-17
    • Brazma, A.1    Freeman, T.2    Gardiner, K.3    Weissman, S.4    Werner, T.5    Korn, B.6
  • 11
    • 32044467658 scopus 로고    scopus 로고
    • Immunization with recombinant modified vaccinia Ankara (rMVA) constructs encoding the HA or NP gene protects ponies from equine influenza virus challenge
    • Breathnach, C. C., H. J. Clark, R. C. Clark, C. W. Olsen, H. G. Townsend, and D. P. Lunn. 2006. Immunization with recombinant modified vaccinia Ankara (rMVA) constructs encoding the HA or NP gene protects ponies from equine influenza virus challenge. Vaccine 24:1180-1190.
    • (2006) Vaccine , vol.24 , pp. 1180-1190
    • Breathnach, C.C.1    Clark, H.J.2    Clark, R.C.3    Olsen, C.W.4    Townsend, H.G.5    Lunn, D.P.6
  • 12
    • 33646549355 scopus 로고    scopus 로고
    • Safety and immunogenicity of an inactivated split-virion influenza A/Vietnam/1194/2004 (H5N1) vaccine: Phase I randomised trial
    • Bresson, J. L., C. Perronne, O. Launay, C. Gerdil, M. Saville, J. Wood, K. Hoschler, and M. C. Zambon. 2006. Safety and immunogenicity of an inactivated split-virion influenza A/Vietnam/1194/2004 (H5N1) vaccine: phase I randomised trial. Lancet 367:1657-1664.
    • (2006) Lancet , vol.367 , pp. 1657-1664
    • Bresson, J.L.1    Perronne, C.2    Launay, O.3    Gerdil, C.4    Saville, M.5    Wood, J.6    Hoschler, K.7    Zambon, M.C.8
  • 13
    • 12744273394 scopus 로고    scopus 로고
    • CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells
    • Cao, W., S. H. Lee, and J. Lu. 2005. CD83 is preformed inside monocytes, macrophages and dendritic cells, but it is only stably expressed on activated dendritic cells. Biochem. J. 385:85-93.
    • (2005) Biochem. J , vol.385 , pp. 85-93
    • Cao, W.1    Lee, S.H.2    Lu, J.3
  • 14
    • 1242316258 scopus 로고    scopus 로고
    • The innate pulmonary granuloma: Characterization and demonstration of dendritic cell recruitment and function
    • Chiu, B. C., C. M. Freeman, V. R. Stolberg, J. S. Hu, E. Komuniecki, and S. W. Chensue. 2004. The innate pulmonary granuloma: characterization and demonstration of dendritic cell recruitment and function. Am. J. Pathol. 164:1021-1030.
    • (2004) Am. J. Pathol , vol.164 , pp. 1021-1030
    • Chiu, B.C.1    Freeman, C.M.2    Stolberg, V.R.3    Hu, J.S.4    Komuniecki, E.5    Chensue, S.W.6
  • 15
    • 33646027625 scopus 로고    scopus 로고
    • Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection
    • Coro, E. S., W. L. Chang, and N. Baumgarth. 2006. Type I IFN receptor signals directly stimulate local B cells early following influenza virus infection. J. Immunol. 176:4343-4351.
    • (2006) J. Immunol , vol.176 , pp. 4343-4351
    • Coro, E.S.1    Chang, W.L.2    Baumgarth, N.3
  • 16
    • 33846965934 scopus 로고    scopus 로고
    • Inactivated and live attenuated influenza vaccines in young children - how do they compare?
    • Cox, N. J., and C. B. Bridges. 2007. Inactivated and live attenuated influenza vaccines in young children - how do they compare? N. Engl. J. Med. 356:729-731.
    • (2007) N. Engl. J. Med , vol.356 , pp. 729-731
    • Cox, N.J.1    Bridges, C.B.2
  • 17
    • 0442323299 scopus 로고    scopus 로고
    • Influenza virus: Immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines
    • Cox, R. J., K. A. Brokstad, and P. Ogra. 2004. Influenza virus: immunity and vaccination strategies. Comparison of the immune response to inactivated and live, attenuated influenza vaccines. Scand. J. Immunol. 59:1-15.
    • (2004) Scand. J. Immunol , vol.59 , pp. 1-15
    • Cox, R.J.1    Brokstad, K.A.2    Ogra, P.3
  • 18
    • 27944445029 scopus 로고    scopus 로고
    • Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung
    • de Bree, G. J., E. M. van Leeuwen, T. A. Out, H. M. Jansen, R. E. Jonkers, and R. A. van Lier. 2005. Selective accumulation of differentiated CD8+ T cells specific for respiratory viruses in the human lung. J. Exp. Med. 202:1433-1442.
    • (2005) J. Exp. Med , vol.202 , pp. 1433-1442
    • de Bree, G.J.1    van Leeuwen, E.M.2    Out, T.A.3    Jansen, H.M.4    Jonkers, R.E.5    van Lier, R.A.6
  • 19
    • 23644442255 scopus 로고    scopus 로고
    • Avian influenza. 'Pandemic vaccine' appears to protect only at high doses
    • Enserink, M. 2005. Avian influenza. 'Pandemic vaccine' appears to protect only at high doses. Science 309:996.
    • (2005) Science , vol.309 , pp. 996
    • Enserink, M.1
  • 20
    • 26244458739 scopus 로고    scopus 로고
    • Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins
    • Falcon, A. M., A. Fernandez-Sesma, Y. Nakaya, T. M. Moran, J. Ortin, and A. Garcia-Sastre. 2005. Attenuation and immunogenicity in mice of temperature-sensitive influenza viruses expressing truncated NS1 proteins. J. Gen. Virol. 86:2817-2821.
    • (2005) J. Gen. Virol , vol.86 , pp. 2817-2821
    • Falcon, A.M.1    Fernandez-Sesma, A.2    Nakaya, Y.3    Moran, T.M.4    Ortin, J.5    Garcia-Sastre, A.6
  • 21
    • 8644243888 scopus 로고    scopus 로고
    • Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes
    • Ferko, B., J. Stasakova, J. Romanova, C. Kittel, S. Sereinig, H. Katinger, and A. Egorov. 2004. Immunogenicity and protection efficacy of replication-deficient influenza A viruses with altered NS1 genes. J. Virol. 78:13037-13045.
    • (2004) J. Virol , vol.78 , pp. 13037-13045
    • Ferko, B.1    Stasakova, J.2    Romanova, J.3    Kittel, C.4    Sereinig, S.5    Katinger, H.6    Egorov, A.7
  • 24
    • 0036678864 scopus 로고    scopus 로고
    • Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: The role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza
    • Geiss, G. K., M. Salvatore, T. M. Tumpey, V. S. Carter, X. Wang, C. F. Basler, J. K. Taubenberger, R. E. Bumgarner, P. Palese, M. G. Katze, and A. Garcia-Sastre. 2002. Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc. Natl. Acad. Sci. USA 99:10736-10741.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10736-10741
    • Geiss, G.K.1    Salvatore, M.2    Tumpey, T.M.3    Carter, V.S.4    Wang, X.5    Basler, C.F.6    Taubenberger, J.K.7    Bumgarner, R.E.8    Palese, P.9    Katze, M.G.10    Garcia-Sastre, A.11
  • 26
    • 0031025178 scopus 로고    scopus 로고
    • Adjuvant activity of the heat-labile enterotoxin from enterotoxigenic Escherichia coli for oral administration of inactivated influenza virus vaccine
    • Katz, J. M., X. Lu, S. A. Young, and J. C. Galphin. 1997. Adjuvant activity of the heat-labile enterotoxin from enterotoxigenic Escherichia coli for oral administration of inactivated influenza virus vaccine. J. Infect. Dis. 175:352-363.
    • (1997) J. Infect. Dis , vol.175 , pp. 352-363
    • Katz, J.M.1    Lu, X.2    Young, S.A.3    Galphin, J.C.4
  • 29
    • 0037565268 scopus 로고    scopus 로고
    • Intracellular warfare between human influenza viruses and human cells: The roles of the viral NS1 protein
    • Krug, R. M., W. Yuan, D. L. Noah, and A. G. Latham. 2003. Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein. Virology 309:181-189.
    • (2003) Virology , vol.309 , pp. 181-189
    • Krug, R.M.1    Yuan, W.2    Noah, D.L.3    Latham, A.G.4
  • 30
    • 0035030376 scopus 로고    scopus 로고
    • Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
    • Le Bon, A., G. Schiavoni, G. D'Agostino, I. Gresser, F. Belardelli, and D. F. Tough. 2001. Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo. Immunity 14:461-470.
    • (2001) Immunity , vol.14 , pp. 461-470
    • Le Bon, A.1    Schiavoni, G.2    D'Agostino, G.3    Gresser, I.4    Belardelli, F.5    Tough, D.F.6
  • 31
    • 0036668242 scopus 로고    scopus 로고
    • Links between innate and adaptive immunity via type I interferon
    • Le Bon, A., and D. F. Tough. 2002. Links between innate and adaptive immunity via type I interferon. Curr. Opin. Immunol. 14:432-436.
    • (2002) Curr. Opin. Immunol , vol.14 , pp. 432-436
    • Le Bon, A.1    Tough, D.F.2
  • 32
    • 33646517711 scopus 로고    scopus 로고
    • Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA
    • Li, S., J. Y. Min, R. M. Krug, and G. C. Sen. 2006. Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology 349:13-21.
    • (2006) Virology , vol.349 , pp. 13-21
    • Li, S.1    Min, J.Y.2    Krug, R.M.3    Sen, G.C.4
  • 33
    • 33748447102 scopus 로고    scopus 로고
    • Lin, J., J. Zhang, X. Dong, H. Fang, J. Chen, N. Su, Q. Gao, Z. Zhang, Y. Liu, Z. Wang, M. Yang, R. Sun, C. Li, S. Lin, M. Ji, X. Wang, J. Wood, Z. Feng, Y. Wang, and W. Yin. 2006. Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial. Lancet 368:991-997.
    • Lin, J., J. Zhang, X. Dong, H. Fang, J. Chen, N. Su, Q. Gao, Z. Zhang, Y. Liu, Z. Wang, M. Yang, R. Sun, C. Li, S. Lin, M. Ji, X. Wang, J. Wood, Z. Feng, Y. Wang, and W. Yin. 2006. Safety and immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1) vaccine: a phase I randomised controlled trial. Lancet 368:991-997.
  • 34
    • 33846061693 scopus 로고    scopus 로고
    • Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus
    • Mibayashi, M., L. Martinez-Sobrido, Y. M. Loo, W. B. Cardenas, M. Gale, Jr., and A. Garcia-Sastre. 2007. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J. Virol. 81:514-524.
    • (2007) J. Virol , vol.81 , pp. 514-524
    • Mibayashi, M.1    Martinez-Sobrido, L.2    Loo, Y.M.3    Cardenas, W.B.4    Gale Jr., M.5    Garcia-Sastre, A.6
  • 35
    • 33646478272 scopus 로고    scopus 로고
    • The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2′-5′ oligo (A) synthetase/RNase L pathway
    • Min, J. Y., and R. M. Krug. 2006. The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: inhibiting the 2′-5′ oligo (A) synthetase/RNase L pathway. Proc. Natl. Acad. Sci. USA 103:7100-7105.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7100-7105
    • Min, J.Y.1    Krug, R.M.2
  • 36
    • 0032874490 scopus 로고    scopus 로고
    • A universal influenza A vaccine based on the extracellular domain of the M2 protein
    • Neirynck, S., T. Deroo, X. Saelens, P. Vanlandschoot, W. M. Jou, and W. Fiers. 1999. A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat. Med. 5:1157-1163.
    • (1999) Nat. Med , vol.5 , pp. 1157-1163
    • Neirynck, S.1    Deroo, T.2    Saelens, X.3    Vanlandschoot, P.4    Jou, W.M.5    Fiers, W.6
  • 37
    • 33751435007 scopus 로고    scopus 로고
    • Influenza vaccine for young children: Two doses are better than one
    • Neuzil, K. M., and J. A. Englund. 2006. Influenza vaccine for young children: two doses are better than one. J. Pediatr. 149:737-738.
    • (2006) J. Pediatr , vol.149 , pp. 737-738
    • Neuzil, K.M.1    Englund, J.A.2
  • 38
    • 33749603340 scopus 로고    scopus 로고
    • Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old children
    • Neuzil, K. M., L. A. Jackson, J. Nelson, A. Klimov, N. Cox, C. B. Bridges, J. Dunn, F. DeStefano, and D. Shay. 2006. Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old children. J. Infect. Dis. 194:1032-1039.
    • (2006) J. Infect. Dis , vol.194 , pp. 1032-1039
    • Neuzil, K.M.1    Jackson, L.A.2    Nelson, J.3    Klimov, A.4    Cox, N.5    Bridges, C.B.6    Dunn, J.7    DeStefano, F.8    Shay, D.9
  • 39
    • 33750984771 scopus 로고    scopus 로고
    • Pichlmair, A., O. Schulz, C. P. Tan, T. I. Naslund, P. Liljestrom, F. Weber, and C. Reis e Sousa. 2006. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314:997-1001.
    • Pichlmair, A., O. Schulz, C. P. Tan, T. I. Naslund, P. Liljestrom, F. Weber, and C. Reis e Sousa. 2006. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5′-phosphates. Science 314:997-1001.
  • 43
    • 0034979498 scopus 로고    scopus 로고
    • Rimmelzwaan, G. F., T. Kuiken, G. van Amerongen, T. M. Bestebroer, R. A. Fouchier, and A. D. Osterhaus. 2001. Pathogenesis of influenza A (H5N1) virus infection in a primate model. J. Virol. 75:6687-6691.
    • Rimmelzwaan, G. F., T. Kuiken, G. van Amerongen, T. M. Bestebroer, R. A. Fouchier, and A. D. Osterhaus. 2001. Pathogenesis of influenza A (H5N1) virus infection in a primate model. J. Virol. 75:6687-6691.
  • 44
    • 0141789643 scopus 로고    scopus 로고
    • Rimmelzwaan, G. F., T. Kuiken, G. van Amerongen, T. M. Bestebroer, R. A. Fouchier, and A. D. Osterhaus. 2003. A primate model to study the pathogenesis of influenza A (H5N1) virus infection. Avian Dis. 47:931-933.
    • Rimmelzwaan, G. F., T. Kuiken, G. van Amerongen, T. M. Bestebroer, R. A. Fouchier, and A. D. Osterhaus. 2003. A primate model to study the pathogenesis of influenza A (H5N1) virus infection. Avian Dis. 47:931-933.
  • 45
    • 19944419799 scopus 로고    scopus 로고
    • Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
    • Solorzano, A., R. J. Webby, K. M. Lager, B. H. Janke, A. Garcia-Sastre, and J. A. Richt. 2005. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J. Virol. 79:7535-7543.
    • (2005) J. Virol , vol.79 , pp. 7535-7543
    • Solorzano, A.1    Webby, R.J.2    Lager, K.M.3    Janke, B.H.4    Garcia-Sastre, A.5    Richt, J.A.6
  • 46
    • 11444262203 scopus 로고    scopus 로고
    • Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18
    • Stasakova, J., B. Ferko, C. Kittel, S. Sereinig, J. Romanova, H. Katinger, and A. Egorov. 2005. Influenza A mutant viruses with altered NS1 protein function provoke caspase-1 activation in primary human macrophages, resulting in fast apoptosis and release of high levels of interleukins 1beta and 18. J. Gen. Virol. 86:185-195.
    • (2005) J. Gen. Virol , vol.86 , pp. 185-195
    • Stasakova, J.1    Ferko, B.2    Kittel, C.3    Sereinig, S.4    Romanova, J.5    Katinger, H.6    Egorov, A.7
  • 47
    • 33748447832 scopus 로고    scopus 로고
    • H5N1 vaccines: How prepared are we for a pandemic?
    • Stephenson, I. 2006. H5N1 vaccines: how prepared are we for a pandemic? Lancet 368:965-966.
    • (2006) Lancet , vol.368 , pp. 965-966
    • Stephenson, I.1
  • 48
    • 33747161889 scopus 로고    scopus 로고
    • Influenza pandemic vaccines: How to ensure a low-cost, low-dose option
    • Stohr, K., M. P. Kieny, and D. Wood. 2006. Influenza pandemic vaccines: how to ensure a low-cost, low-dose option. Nat. Rev. Microbiol. 4:565-566.
    • (2006) Nat. Rev. Microbiol , vol.4 , pp. 565-566
    • Stohr, K.1    Kieny, M.P.2    Wood, D.3
  • 49
    • 0033870894 scopus 로고    scopus 로고
    • Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein
    • Talon, J., C. M. Horvath, R. Polley, C. F. Basler, T. Muster, P. Palese, and A. Garcia-Sastre. 2000. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J. Virol. 74:7989-7996.
    • (2000) J. Virol , vol.74 , pp. 7989-7996
    • Talon, J.1    Horvath, C.M.2    Polley, R.3    Basler, C.F.4    Muster, T.5    Palese, P.6    Garcia-Sastre, A.7
  • 51
    • 33746706764 scopus 로고    scopus 로고
    • Use of human nasal cannulas during bronchoscopy procedures as a simple method for maintaining adequate oxygen saturation in pigtailed macaques (Macaca nemestrina)
    • Thomas, M. J., L. R. Flanary, B. A. Brown, M. G. Katze, and C. R. Baskin. 2006. Use of human nasal cannulas during bronchoscopy procedures as a simple method for maintaining adequate oxygen saturation in pigtailed macaques (Macaca nemestrina). J. Am. Assoc. Lab. Anim. Sci. 45:44-48.
    • (2006) J. Am. Assoc. Lab. Anim. Sci , vol.45 , pp. 44-48
    • Thomas, M.J.1    Flanary, L.R.2    Brown, B.A.3    Katze, M.G.4    Baskin, C.R.5
  • 52
    • 0034466776 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein prevents activation of NF-κB and induction of alpha/beta interferon
    • Wang, X., M. Li, H. Zheng, T. Muster, P. Palese, A. A. Beg, and A. Garcia-Sastre. 2000. Influenza A virus NS1 protein prevents activation of NF-κB and induction of alpha/beta interferon. J. Virol. 74:11566-11573.
    • (2000) J. Virol , vol.74 , pp. 11566-11573
    • Wang, X.1    Li, M.2    Zheng, H.3    Muster, T.4    Palese, P.5    Beg, A.A.6    Garcia-Sastre, A.7


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