Disregulated influenza A virus-specific CD8+ T cell homeostasis in the absence of IFN-γ signaling

Journal of Immunology

Volumn 178, Issue 12, 2007, Pages 7616-7622

  Turner, Stephen J ^a,b   Olivas, Elvia ^a   Gutierrez, Astrid ^a   Diaz, Gabriela ^a   Doherty, Peter C ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN SPECIFICITY; APOPTOSIS; ARTICLE; BINDING SITE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; EFFECTOR CELL; INFLUENZA VIRUS A; INTERFERON PRODUCTION; LUNG LAVAGE; MEDIASTINUM LYMPH NODE; MOUSE; NONHUMAN; PREVALENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE ACTIVATION;

EID: 34250212458     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.12.7616     Document Type: Article

References (36)

1. Kaech, S. M., S. Hemby, E. Kersh, and R. Ahmed. 2002. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111: 837-851.
2. + T cells. Nature 401: 76-79.
3. Masopusi, D., V. Vezys, A. L. Marzo, and L. Lefrancois. 2001. Preferential localization of effector memory cells in nonlymphoid tissue. Science 291: 2413-2417.
4. + T cells. Proc. Natl. Acad. Sci. USA 98: 6313-6318.
5. Yang, Y., J. B. Waters, K. Fruh, and P. A. Peterson. 1992. Proteasomes are regulated by interferon γ: implications for antigen processing. Proc. Natl. Acad. Sci. USA 89: 4928-4932.
6. Refaeli, Y., L. Van Parijs, S. I. Alexander, and A. K. Abbas. 2002. Interferon γ is required for activation-induced death of T lymphocytes. J. Exp. Med. 196: 999-1005.
7. + T cell homeostasis by perforin and interferon-γ. Science 290: 1354-1358.
8. Dalton, D. K., L. Haynes, C. Q. Chu, S. L. Swain, and S. Wittmer. 2000. Interferon γ eliminates responding CD4 T cells during mycobacterial infection by inducing apoptosis of activated CD4 T cells. J. Exp. Med. 192: 117-122.
9. + T cells to increase their abundance during virus infection. J. Exp. Med. 201: 1053-1059.
10. Baumgarth, N., and A. Kelso. 1996. In vivo blockade of γ interferon affects the influenza virus-induced humoral and the local cellular immune response in lung tissue. J. Virol. 70: 4411-4418.
11. Savinov, A. Y., F. S. Wong, and A. V. Chervonsky. 2001. IFN-γ affects homing of diabetogenic T cells. J. Immunol. 167: 6637-6643.
12. + T cells. J. Immunol. 144: 3980-3986.
13. + T-cell responses to influenza virus. J. Virol. 76: 10332-10337.
14. Karupiah, G., J. H. Chen, S. Mahalingam, C. F. Nathan, and J. D. MacMicking. 1998. Rapid interferon γ-dependent clearance of influenza A virus and protection from consolidating pneumonitis in nitric oxide synthase 2-delicient mice. J. Exp. Med. 188: 1541-1546.
15. Graham, M. B., D. K. Dalton, D. Giltinan, V. L. Braciale, T. A. Stewart, and T. J. Braciale. 1993. Response to influenza infection in mice with a targeted disruption in the interferon γ gene. J. Exp. Med. 178: 1725-1732.
16. + T cells in primary and secondary influenza pneumonia. Immunity 8: 683-691.
17. + T-cell response is much less apparent following secondary challenge. J. Virol. 74: 3486-3493.
18. + T cell responses. J. Immunol. 166: 4627-4633.
19. 2-microglobulin- defieient mice delays influenza virus clearance but docs not switch the response to a T helper cell 2 phenotype. J. Immunol. 153: 1246-1253.
20. + T cell-mediated control of a gamma-herpesvirus in B cell-deficient mice is mediated by IFN-γ. Proc. Natl. Acad. Sci. USA 96: 5135-5140.
21. + T cells after infection. Nat. Immunol. 3: 619-626.
22. - T cell responses: correlation of cytokine profile and TCR avidity. J. Immunol. 172: 5553-5560.
23. Butcher, E. C., M. Williams, K. Youngman, L. Rott, and M. Briskin. 1999. Lymphocyte trafficking and regional immunity. Adv. Immunol. 72: 209-253.
24. Kawai, T., M. Seki, K. Hiromatsu, J. W. Eastcott, G. F. Watts, M. Sugai, D. J. Smith, S. A. Porcelli, and M. A. Taubman. 1999. Selective diapedesis of Th1 cells induced by endothelial cell RANTES. J. Immunol. 163: 3269-3278.
25. Dawson, T. C., M. A. Beck, W. A. Kuziel, F. Henderson, and N. Maeda. 2000. Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus. Am. J. Pathol. 156: 1951-1959.
26. + T cell immunodominance in primary and secondary influenza virus infections. J. Exp. Med. 198: 399-410.
27. + effector T cells. Proc. Natl. Acad. Sci. USA 101: 3545-3550.
28. + lymphocyte subsets. Microb. Pathog. 14: 75-84.
29. Slifka, M. K., and J. L. Whitton. 2000. Antigen-specific regulation of T cell-mediated cytokine production. Immunity 12: 451-457.
30. + T cell responses. J. Immunol. 175: 5624-5628.
31. Skrenta, H., Y. Yang, S. Pestka, and C. G. Rahman. 2000. Ligand-independent down-regulation of IFN-γ receptor 1 following TCR engagement. J. Immunol. 164: 3506-3511.
32. + T cells responding to infection. J. Immunol. 174: 6791-6802.
33. 4 integrins and the immune response. Immunol. Rev. 186: 118-124.
34. 4 integrins from adult hematopoietic cells reveals roles in homeostasis, regeneration, and homing. Mol. Cell. Biol. 23: 9349-9360.
35. Lo, C. G., T. T. Lu, and J. G. Cyster. 2003. Integrin-dependence of lymphocyte entry into the splenic white pulp. J. Exp. Med. 197: 353-361.
36. 1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection. Immunity 20: 167-179.