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Volumn 81, Issue 13, 2007, Pages 7011-7021

Multiple anti-interferon actions of the influenza A virus NS1 protein

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR; GENE PRODUCT; INTERFERON; INTERFERON ANTIBODY; INTERFERON REGULATORY FACTOR 3; MESSENGER RNA; MESSENGER RNA PRECURSOR; METHIONINE; NONSTRUCTURAL PROTEIN 1; PHENYLALANINE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 34250810666     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02581-06     Document Type: Article
Times cited : (387)

References (76)
  • 1
    • 0033838456 scopus 로고    scopus 로고
    • Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus
    • Aragon, T., S. de la Luna, I. Novoa, L. Carrasco, J. Ortin, and A. Nieto. 2000. Eukaryotic translation initiation factor 4GI is a cellular target for NS1 protein, a translational activator of influenza virus. Mol. Cell. Biol. 20:6259-6268.
    • (2000) Mol. Cell. Biol , vol.20 , pp. 6259-6268
    • Aragon, T.1    de la Luna, S.2    Novoa, I.3    Carrasco, L.4    Ortin, J.5    Nieto, A.6
  • 2
    • 0023879695 scopus 로고
    • Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus
    • Baichwal, V. R., and B. Sugden. 1988. Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus. Oncogene 2:461-467.
    • (1988) Oncogene , vol.2 , pp. 461-467
    • Baichwal, V.R.1    Sugden, B.2
  • 3
    • 4544271953 scopus 로고    scopus 로고
    • Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina)
    • Baskin, C. R., A. Garcia-Sastre, T. M. Tumpey, H. Bielefeldt-Ohmann, V. S. Carter, E. Nistal-Villan, and M. G. Katze. 2004. Integration of clinical data, pathology, and cDNA microarrays in influenza virus-infected pigtailed macaques (Macaca nemestrina). J. Virol. 78:10420-10432.
    • (2004) J. Virol , vol.78 , pp. 10420-10432
    • Baskin, C.R.1    Garcia-Sastre, A.2    Tumpey, T.M.3    Bielefeldt-Ohmann, H.4    Carter, V.S.5    Nistal-Villan, E.6    Katze, M.G.7
  • 7
    • 33744925682 scopus 로고    scopus 로고
    • X-ray structure of influenza virus NS1 effector domain
    • Bornholdt, Z. A., and B. V. Prasad. 2006. X-ray structure of influenza virus NS1 effector domain. Nat. Struct. Mol. Biol. 13:559-560.
    • (2006) Nat. Struct. Mol. Biol , vol.13 , pp. 559-560
    • Bornholdt, Z.A.1    Prasad, B.V.2
  • 8
    • 1842832222 scopus 로고    scopus 로고
    • The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants
    • Bucher, E., H. Hemmes, P. de Haan, R. Goldbach, and M. Prins. 2004. The influenza A virus NS1 protein binds small interfering RNAs and suppresses RNA silencing in plants. J. Gen. Virol. 85:983-991.
    • (2004) J. Gen. Virol , vol.85 , pp. 983-991
    • Bucher, E.1    Hemmes, H.2    de Haan, P.3    Goldbach, R.4    Prins, M.5
  • 9
    • 0032888955 scopus 로고    scopus 로고
    • Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter
    • Buchholz, U. J., S. Finke, and K. K. Conzelmann. 1999. Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter. J. Virol. 73:251-259.
    • (1999) J. Virol , vol.73 , pp. 251-259
    • Buchholz, U.J.1    Finke, S.2    Conzelmann, K.K.3
  • 10
    • 0346121589 scopus 로고    scopus 로고
    • PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes
    • Burgui, I., T. Aragon, J. Ortin, and A. Nieto. 2003. PABP1 and eIF4GI associate with influenza virus NS1 protein in viral mRNA translation initiation complexes. J. Gen. Virol. 84:3263-3274.
    • (2003) J. Gen. Virol , vol.84 , pp. 3263-3274
    • Burgui, I.1    Aragon, T.2    Ortin, J.3    Nieto, A.4
  • 12
    • 0033560753 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3′-end processing machinery
    • Chen, Z., Y. Li, and R. M. Krug. 1999. Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3′-end processing machinery. EMBO J. 18:2273-2283.
    • (1999) EMBO J , vol.18 , pp. 2273-2283
    • Chen, Z.1    Li, Y.2    Krug, R.M.3
  • 14
    • 0032731094 scopus 로고    scopus 로고
    • The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation
    • Didcock, L., D. F. Young, S. Goodbourn, and R. E. Randall. 1999. The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradation. J. Virol. 73:9928-9933.
    • (1999) J. Virol , vol.73 , pp. 9928-9933
    • Didcock, L.1    Young, D.F.2    Goodbourn, S.3    Randall, R.E.4
  • 15
    • 0345167006 scopus 로고    scopus 로고
    • A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice
    • Donelan, N. R., C. F. Basler, and A. Garcia-Sastre. 2003. A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice. J. Virol. 77:13257-13266.
    • (2003) J. Virol , vol.77 , pp. 13257-13266
    • Donelan, N.R.1    Basler, C.F.2    Garcia-Sastre, A.3
  • 18
    • 0033461161 scopus 로고    scopus 로고
    • The central interactive region of human MxA GTPase is involved in GTPase activation and interaction with viral target structures
    • Flohr, F., S. Schneider-Schaulies, O. Haller, and G. Kochs. 1999. The central interactive region of human MxA GTPase is involved in GTPase activation and interaction with viral target structures. FEBS Lett. 463:24-28.
    • (1999) FEBS Lett , vol.463 , pp. 24-28
    • Flohr, F.1    Schneider-Schaulies, S.2    Haller, O.3    Kochs, G.4
  • 20
    • 0028008470 scopus 로고
    • Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport
    • Fortes, P., A. Beloso, and J. Ortin. 1994. Influenza virus NS1 protein inhibits pre-mRNA splicing and blocks mRNA nucleocytoplasmic transport. EMBO J. 13:704-712.
    • (1994) EMBO J , vol.13 , pp. 704-712
    • Fortes, P.1    Beloso, A.2    Ortin, J.3
  • 21
    • 0035864298 scopus 로고    scopus 로고
    • Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses
    • Garcia-Sastre, A. 2001. Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA viruses. Virology 279:375-384.
    • (2001) Virology , vol.279 , pp. 375-384
    • Garcia-Sastre, A.1
  • 22
    • 33646555810 scopus 로고    scopus 로고
    • Type 1 interferons and the virus-host relationship: A lesson in detente
    • Garcia-Sastre, A., and C. A. Biron. 2006. Type 1 interferons and the virus-host relationship: a lesson in detente. Science 312:879-882.
    • (2006) Science , vol.312 , pp. 879-882
    • Garcia-Sastre, A.1    Biron, C.A.2
  • 24
    • 0036678864 scopus 로고    scopus 로고
    • Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: The role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza
    • Geiss, G. K., M. Salvatore, T. M. Tumpey, V. S. Carter, X. Wang, C. F. Basler, J. K. Taubenberger, R. E. Bumgarner, P. Palese, M. G. Katze, and A. Garcia-Sastre. 2002. Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza. Proc. Natl. Acad. Sci. USA 99:10736-10741.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 10736-10741
    • Geiss, G.K.1    Salvatore, M.2    Tumpey, T.M.3    Carter, V.S.4    Wang, X.5    Basler, C.F.6    Taubenberger, J.K.7    Bumgarner, R.E.8    Palese, P.9    Katze, M.G.10    Garcia-Sastre, A.11
  • 27
    • 33749004778 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling
    • Hale, B. G., D. Jackson, Y. H. Chen, R. A. Lamb, and R. E. Randall. 2006. Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling. Proc. Natl. Acad. Sci. USA 103:14194-14199.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 14194-14199
    • Hale, B.G.1    Jackson, D.2    Chen, Y.H.3    Lamb, R.A.4    Randall, R.E.5
  • 28
    • 0036788192 scopus 로고    scopus 로고
    • Interferon-induced Mx proteins: Dynamin-like GTPases with antiviral activity
    • Haller, O., and G. Kochs. 2002. Interferon-induced Mx proteins: dynamin-like GTPases with antiviral activity. Traffic 3:710-717.
    • (2002) Traffic , vol.3 , pp. 710-717
    • Haller, O.1    Kochs, G.2
  • 29
    • 29144501207 scopus 로고    scopus 로고
    • The interferon response circuit: Induction and suppression by pathogenic viruses
    • Haller, O., G. Kochs, and F. Weber. 2006. The interferon response circuit: induction and suppression by pathogenic viruses. Virology 344:119-130.
    • (2006) Virology , vol.344 , pp. 119-130
    • Haller, O.1    Kochs, G.2    Weber, F.3
  • 30
    • 0032980412 scopus 로고    scopus 로고
    • Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells
    • Hatada, E., S. Saito, and R. Fukuda. 1999. Mutant influenza viruses with a defective NS1 protein cannot block the activation of PKR in infected cells. J. Virol. 73:2425-2433.
    • (1999) J. Virol , vol.73 , pp. 2425-2433
    • Hatada, E.1    Saito, S.2    Fukuda, R.3
  • 31
    • 33645037542 scopus 로고    scopus 로고
    • Variation in the ability of human influenza A viruses to induce and inhibit the IFN-beta pathway
    • Hayman, A., S. Comely, A. Lackenby, S. Murphy, J. McCauley, S. Goodbourn, and W. Barclay. 2006. Variation in the ability of human influenza A viruses to induce and inhibit the IFN-beta pathway. Virology 347:52-64.
    • (2006) Virology , vol.347 , pp. 52-64
    • Hayman, A.1    Comely, S.2    Lackenby, A.3    Murphy, S.4    McCauley, J.5    Goodbourn, S.6    Barclay, W.7
  • 33
    • 0023696621 scopus 로고
    • Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter
    • Hug, H., M. Costas, P. Staeheli, M. Aebi, and C. Weissmann. 1988. Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter. Mol. Cell. Biol. 8:3065-3079.
    • (1988) Mol. Cell. Biol , vol.8 , pp. 3065-3079
    • Hug, H.1    Costas, M.2    Staeheli, P.3    Aebi, M.4    Weissmann, C.5
  • 34
    • 0035047145 scopus 로고    scopus 로고
    • Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: Common and unique pathways
    • Iwamura, T., M. Yoneyama, K. Yamaguchi, W. Suhara, W. Mori, K. Shiota, Y. Okabe, H. Namiki, and T. Fujita. 2001. Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways. Genes Cells 6:375-388.
    • (2001) Genes Cells , vol.6 , pp. 375-388
    • Iwamura, T.1    Yoneyama, M.2    Yamaguchi, K.3    Suhara, W.4    Mori, W.5    Shiota, K.6    Okabe, Y.7    Namiki, H.8    Fujita, T.9
  • 36
    • 0028171911 scopus 로고
    • The beta-interferon promoter responds to priming through multiple independent regulatory elements
    • King, P., and S. Goodbourn. 1994. The beta-interferon promoter responds to priming through multiple independent regulatory elements. J. Biol. Chem. 269:30609-30615.
    • (1994) J. Biol. Chem , vol.269 , pp. 30609-30615
    • King, P.1    Goodbourn, S.2
  • 40
    • 0037565268 scopus 로고    scopus 로고
    • Intracellular warfare between human influenza viruses and human cells: The roles of the viral NS1 protein
    • Krug, R. M., W. Yuan, D. L. Noah, and A. G. Latham. 2003. Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein. Virology 309:181-189.
    • (2003) Virology , vol.309 , pp. 181-189
    • Krug, R.M.1    Yuan, W.2    Noah, D.L.3    Latham, A.G.4
  • 41
    • 0001178029 scopus 로고    scopus 로고
    • Orthomyxoviridae: The viruses and their replication
    • D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus ed, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA
    • Lamb, R. A., and R. M. Krug. 2001. Orthomyxoviridae: the viruses and their replication, p. 1487-1532. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
    • (2001) Fields virology , pp. 1487-1532
    • Lamb, R.A.1    Krug, R.M.2
  • 42
    • 3242749934 scopus 로고    scopus 로고
    • RIGging an antiviral defense - it's in the CARDs
    • Levy, D. E., and I. J. Marie. 2004. RIGging an antiviral defense - it's in the CARDs. Nat. Immunol. 5:699-701.
    • (2004) Nat. Immunol , vol.5 , pp. 699-701
    • Levy, D.E.1    Marie, I.J.2
  • 43
    • 33646517711 scopus 로고    scopus 로고
    • Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA
    • Li, S., J. Y. Min, R. M. Krug, and G. C. Sen. 2006. Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA. Virology 349:13-21.
    • (2006) Virology , vol.349 , pp. 13-21
    • Li, S.1    Min, J.Y.2    Krug, R.M.3    Sen, G.C.4
  • 45
    • 0028040760 scopus 로고
    • The influenza virus NS1 protein: A novel inhibitor of pre-mRNA splicing
    • Lu, Y., X. Y. Qian, and R. M. Krug. 1994. The influenza virus NS1 protein: a novel inhibitor of pre-mRNA splicing. Genes Dev. 8:1817-1828.
    • (1994) Genes Dev , vol.8 , pp. 1817-1828
    • Lu, Y.1    Qian, X.Y.2    Krug, R.M.3
  • 47
    • 33846061693 scopus 로고    scopus 로고
    • Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus
    • Mibayashi, M., L. Martinez-Sobrido, Y. M. Loo, W. B. Cardenas, M. Gale, Jr., and A. Garcia-Sastre. 2007. Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virus. J. Virol. 81:514-524.
    • (2007) J. Virol , vol.81 , pp. 514-524
    • Mibayashi, M.1    Martinez-Sobrido, L.2    Loo, Y.M.3    Cardenas, W.B.4    Gale Jr., M.5    Garcia-Sastre, A.6
  • 48
    • 33646478272 scopus 로고    scopus 로고
    • The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2′-5′ oligo(A) synthetase/RNase L pathway
    • Min, J. Y., and R. M. Krug. 2006. The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: inhibiting the 2′-5′ oligo(A) synthetase/RNase L pathway. Proc. Natl. Acad. Sci. USA 103:7100-7105.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 7100-7105
    • Min, J.Y.1    Krug, R.M.2
  • 49
    • 0032086357 scopus 로고    scopus 로고
    • Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3′end formation of cellular pre-mRNAs
    • Nemeroff, M. E., S. M. Barabino, Y. Li, W. Keller, and R. M. Krug. 1998. Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3′end formation of cellular pre-mRNAs. Mol. Cell 1:991-1000.
    • (1998) Mol. Cell , vol.1 , pp. 991-1000
    • Nemeroff, M.E.1    Barabino, S.M.2    Li, Y.3    Keller, W.4    Krug, R.M.5
  • 50
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa, H., K. Yamamura, and J. Miyazali. 1991. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-199.
    • (1991) Gene , vol.108 , pp. 193-199
    • Niwa, H.1    Yamamura, K.2    Miyazali, J.3
  • 51
    • 0037444193 scopus 로고    scopus 로고
    • Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3′ end processing of cellular pre-mRNAs
    • Noah, D. L., K. Y. Twu, and R. M. Krug. 2003. Cellular antiviral responses against influenza A virus are countered at the posttranscriptional level by the viral NS1A protein via its binding to a cellular protein required for the 3′ end processing of cellular pre-mRNAs. Virology 307:386-395.
    • (2003) Virology , vol.307 , pp. 386-395
    • Noah, D.L.1    Twu, K.Y.2    Krug, R.M.3
  • 53
    • 10944240992 scopus 로고    scopus 로고
    • Influenza: Old and new threats
    • Palese, P. 2004. Influenza: old and new threats. Nat. Med. 10:S82-S87.
    • (2004) Nat. Med , vol.10
    • Palese, P.1
  • 54
    • 0037223757 scopus 로고    scopus 로고
    • Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins
    • Park, M.-S., M. L. Shaw, J. Munoz-Jordan, J. F. Cros, T. Nakaya, N. Bouvier, P. Palese, A. Garcia-Sastre, and C. F. Basler. 2003. Newcastle disease virus (NDV)-based assay demonstrates interferon-antagonist activity for the NDV V protein and the Nipah virus V, W, and C proteins. J. Virol. 77:1501-1511.
    • (2003) J. Virol , vol.77 , pp. 1501-1511
    • Park, M.-S.1    Shaw, M.L.2    Munoz-Jordan, J.3    Cros, J.F.4    Nakaya, T.5    Bouvier, N.6    Palese, P.7    Garcia-Sastre, A.8    Basler, C.F.9
  • 56
    • 0033015827 scopus 로고    scopus 로고
    • Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template
    • Poon, L. L., D. C. Pritlove, E. Fodor, and G. G. Brownlee. 1999. Direct evidence that the poly(A) tail of influenza A virus mRNA is synthesized by reiterative copying of a U track in the virion RNA template. J. Virol. 73:3473-3476.
    • (1999) J. Virol , vol.73 , pp. 3473-3476
    • Poon, L.L.1    Pritlove, D.C.2    Fodor, E.3    Brownlee, G.G.4
  • 57
    • 0028274131 scopus 로고
    • The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A)
    • Qiu, Y., and R. M. Krug. 1994. The influenza virus NS1 protein is a poly(A)-binding protein that inhibits nuclear export of mRNAs containing poly(A). J. Virol. 68:2425-2432.
    • (1994) J. Virol , vol.68 , pp. 2425-2432
    • Qiu, Y.1    Krug, R.M.2
  • 58
    • 0036147256 scopus 로고    scopus 로고
    • Effects of influenza A virus NS1 protein on protein expression: The NS1 protein enhances translation and is not required for shutoff of host protein synthesis
    • Salvatore, M., C. F. Basler, J. P. Parisien, C. M. Horvath, S. Bourmakina, H. Zheng, T. Muster, P. Palese, and A. Garcia-Sastre. 2002. Effects of influenza A virus NS1 protein on protein expression: the NS1 protein enhances translation and is not required for shutoff of host protein synthesis. J. Virol. 76:1206-1212.
    • (2002) J. Virol , vol.76 , pp. 1206-1212
    • Salvatore, M.1    Basler, C.F.2    Parisien, J.P.3    Horvath, C.M.4    Bourmakina, S.5    Zheng, H.6    Muster, T.7    Palese, P.8    Garcia-Sastre, A.9
  • 59
    • 0034767753 scopus 로고    scopus 로고
    • Antiviral action of interferons
    • Samuel, C. E. 2001. Antiviral action of interferons. Clin. Microbiol. Rev. 14:778-809.
    • (2001) Clin. Microbiol. Rev , vol.14 , pp. 778-809
    • Samuel, C.E.1
  • 63
    • 0036734038 scopus 로고    scopus 로고
    • Lethal H5N1 influenza viruses escape host anti-viral cytokine response
    • Seo, S. H., E. Hoffmann, and R. G. Webster. 2002. Lethal H5N1 influenza viruses escape host anti-viral cytokine response. Nat. Med. 8:950-954.
    • (2002) Nat. Med , vol.8 , pp. 950-954
    • Seo, S.H.1    Hoffmann, E.2    Webster, R.G.3
  • 64
    • 0036710523 scopus 로고    scopus 로고
    • Multiple signaling pathways leading to the activation of interferon regulatory factor 3
    • Servant, M. J., N. Grandvaux, and J. Hiscott. 2002. Multiple signaling pathways leading to the activation of interferon regulatory factor 3. Biochem. Pharmacol. 64:985-992.
    • (2002) Biochem. Pharmacol , vol.64 , pp. 985-992
    • Servant, M.J.1    Grandvaux, N.2    Hiscott, J.3
  • 65
    • 2442661542 scopus 로고    scopus 로고
    • Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively
    • Shaw, M. L., A. Garcia-Sastre, P. Palese, and C. F. Basler. 2004. Nipah virus V and W proteins have a common STAT1-binding domain yet inhibit STAT1 activation from the cytoplasmic and nuclear compartments, respectively. J. Virol. 78:5633-5641.
    • (2004) J. Virol , vol.78 , pp. 5633-5641
    • Shaw, M.L.1    Garcia-Sastre, A.2    Palese, P.3    Basler, C.F.4
  • 66
    • 0035937802 scopus 로고    scopus 로고
    • IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by vaccinia virus E3L protein
    • Smith, E. J., I. Marie, A. Prakash, A. Garcia-Sastre, and D. E. Levy. 2001. IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by vaccinia virus E3L protein. J. Biol. Chem. 276:8951-8957.
    • (2001) J. Biol. Chem , vol.276 , pp. 8951-8957
    • Smith, E.J.1    Marie, I.2    Prakash, A.3    Garcia-Sastre, A.4    Levy, D.E.5
  • 67
    • 19944419799 scopus 로고    scopus 로고
    • Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs
    • Solorzano, A., R. J. Webby, K. M. Lager, B. H. Janke, A. Garcia-Sastre, and J. A. Richt. 2005. Mutations in the NS1 protein of swine influenza virus impair anti-interferon activity and confer attenuation in pigs. J. Virol. 79: 7535-7543.
    • (2005) J. Virol , vol.79 , pp. 7535-7543
    • Solorzano, A.1    Webby, R.J.2    Lager, K.M.3    Janke, B.H.4    Garcia-Sastre, A.5    Richt, J.A.6
  • 68
    • 0033870894 scopus 로고    scopus 로고
    • Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein
    • Talon, J., C. M. Horvath, R. Polley, C. F. Basler, T. Muster, P. Palese, and A. Garcia-Sastre. 2000. Activation of interferon regulatory factor 3 is inhibited by the influenza A virus NS1 protein. J. Virol. 74:7989-7996.
    • (2000) J. Virol , vol.74 , pp. 7989-7996
    • Talon, J.1    Horvath, C.M.2    Polley, R.3    Basler, C.F.4    Muster, T.5    Palese, P.6    Garcia-Sastre, A.7
  • 70
    • 33645792617 scopus 로고    scopus 로고
    • The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target
    • Twu, K. Y., D. L. Noah, P. Rao, R. L. Kuo, and R. M. Krug. 2006. The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target. J. Virol. 80:3957-3965.
    • (2006) J. Virol , vol.80 , pp. 3957-3965
    • Twu, K.Y.1    Noah, D.L.2    Rao, P.3    Kuo, R.L.4    Krug, R.M.5
  • 71
    • 0032995665 scopus 로고    scopus 로고
    • RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids
    • Wang, W., K. Riedel, P. Lynch, C. Y. Chien, G. T. Montelione, and R. M. Krug. 1999. RNA binding by the novel helical domain of the influenza virus NS1 protein requires its dimer structure and a small number of specific basic amino acids. RNA 5:195-205.
    • (1999) RNA , vol.5 , pp. 195-205
    • Wang, W.1    Riedel, K.2    Lynch, P.3    Chien, C.Y.4    Montelione, G.T.5    Krug, R.M.6
  • 72
    • 0036891842 scopus 로고    scopus 로고
    • Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains
    • Wang, X., C. F. Basler, B. R. Williams, R. H. Silverman, P. Palese, and A. Garcia-Sastre. 2002. Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains. J. Virol. 76:12951-12962.
    • (2002) J. Virol , vol.76 , pp. 12951-12962
    • Wang, X.1    Basler, C.F.2    Williams, B.R.3    Silverman, R.H.4    Palese, P.5    Garcia-Sastre, A.6
  • 73
    • 0034466776 scopus 로고    scopus 로고
    • Influenza A virus NS1 protein prevents the activation of NF-κB and induction of type I interferon
    • Wang, X., M. Li, H. Zheng, T. Muster, P. Palese, A. A. Beg, and A. Garcia-Sastre. 2000. Influenza A virus NS1 protein prevents the activation of NF-κB and induction of type I interferon. J. Virol. 74:11566-11573.
    • (2000) J. Virol , vol.74 , pp. 11566-11573
    • Wang, X.1    Li, M.2    Zheng, H.3    Muster, T.4    Palese, P.5    Beg, A.A.6    Garcia-Sastre, A.7
  • 74
    • 0035264584 scopus 로고    scopus 로고
    • The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon system
    • Weber, F., E. F. Dunn, A. Bridgen, and R. M. Elliott. 2001. The Bunyamwera virus nonstructural protein NSs inhibits viral RNA synthesis in a minireplicon system. Virology 281:67-74.
    • (2001) Virology , vol.281 , pp. 67-74
    • Weber, F.1    Dunn, E.F.2    Bridgen, A.3    Elliott, R.M.4
  • 75
    • 0032481352 scopus 로고    scopus 로고
    • Direct triggering of the IFN-alpha/beta system by virus infection: Activation of a transcription factor complex containing IRF-3 and CBP/ p300
    • Yoneyama, M., W. Suhara, Y. Fukuhara, M. Fukuda, E. Nishida, and T. Fujita. 1998. Direct triggering of the IFN-alpha/beta system by virus infection: activation of a transcription factor complex containing IRF-3 and CBP/ p300. EMBO J. 17:1087-1095.
    • (1998) EMBO J , vol.17 , pp. 1087-1095
    • Yoneyama, M.1    Suhara, W.2    Fukuhara, Y.3    Fukuda, M.4    Nishida, E.5    Fujita, T.6
  • 76
    • 0033061223 scopus 로고    scopus 로고
    • Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication
    • Zheng, H., H. A. Lee, P. Palese, and A. Garcia-Sastre. 1999. Influenza A virus RNA polymerase has the ability to stutter at the polyadenylation site of a viral RNA template during RNA replication. J. Virol. 73:5240-5243.
    • (1999) J. Virol , vol.73 , pp. 5240-5243
    • Zheng, H.1    Lee, H.A.2    Palese, P.3    Garcia-Sastre, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.