Genomic analysis of increased host immune and cell death responses induced by 1918 influenza virus

Nature

Volumn 443, Issue 7111, 2006, Pages 578-581

  Kash, John C ^a   Tumpey, Terrence M ^b   Proll, Sean C ^c   Carter, Victoria ^c   Perwitasari, Olivia ^a   Thomas, Matthew J ^c   Basler, Christopher F ^d   Palese, Peter ^d   Taubenberger, Jeffery K ^e,g   García Sastre, Adolfo ^d   Swayne, David E ^f   Katze, Michael G ^a,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^c Washington National Primate Research Center   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e ARMED FORCES INSTITUTE OF PATHOLOGY   (United States)

^f U S DEPARTMENT OF AGRICULTURE   (United States)

^g NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; GENETIC ENGINEERING; PATHOLOGY; PULMONARY DISEASES; VIRUSES;

ANTIVIRAL THERAPIES; AVIAN INFLUENZA; IMMUNE RESPONSES; INFLUENZA VIRUS;

IMMUNOLOGY;

GENETIC ANALYSIS; HISTOPATHOLOGY; IMMUNE RESPONSE; INFLUENZA; PATHOLOGY; RODENT; VIRAL DISEASE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BRONCHITIS; CELL DEATH; CELL FUNCTION; CELLULAR IMMUNITY; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENOME; HISTOPATHOLOGY; HOST; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INFLAMMATORY CELL; INFLUENZA H1N1 VIRUS; INFLUENZA VIRUS; LUNG ALVEOLITIS; LUNG EDEMA; LUNG HEMORRHAGE; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROGNOSIS; TH1 CELL; TREATMENT PLANNING; VIRUS INFECTION; VIRUS STRAIN; VIRUS VIRULENCE;

AVIAN INFLUENZA VIRUS; ORTHOMYXOVIRIDAE;

EID: 33749514992     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05181     Document Type: Article

References (26)

1. Johnson, N. P. & Mueller, J. Updating the accounts: global mortality of the 1918-1920 'Spanish' influenza pandemic. Bull. Hist. Med. 76, 105-115 (2002).
2. Taubenberger, J. K. & Morens, D. M. 1918 influenza: the mother of all pandemics. Emerg. Infect. Dis. 12, 15-22 (2006).
3. Tumpey, T. M. et al. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 310, 77-80 (2005).
4. Kobasa, D. et al. Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus. Nature 431, 703-707 (2004).
5. Kash, J. C. et al. Global host immune response: pathogenesis and transcriptional profiling of type A influenza viruses expressing the hemagglutinin and neuraminidase genes from the 1918 pandemic virus. J. Virol. 78, 9499-9511 (2004).
6. Tumpey, T. M. et al. Pathogenicity of influenza viruses with genes from the 1918 pandemic virus: functional roles of alveolar macrophages and neutrophils in limiting virus replication and mortality in mice. J. Virol. 79, 14933-14944 (2005).
7. Zhou, J. et al. Differential expression of chemokines and their receptors in adult and neonatal macrophages infected with human or avian influenza viruses. J. Infect. Dis. 194, 61-70 (2006).
8. Cheung, C. Y. et al. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 360, 1831-1837 (2002).
9. Zhou, J. et al. Functional tumor necrosis factor-related apoptosis-inducing ligand production by avian influenza virus-infected macrophages. J. Infect. Dis. 193, 945-953 (2006).
10. Chen, W. et al. A novel influenza A virus mitochondrial protein that induces cell death. Nature Med. 7, 1306-1312 (2001).
11. Zamarin, D., Garcia-Sastre, A., Xiao, X., Wang, R. & Palese, P. Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1. PLoS Pathog. 1, e4 (2005).
12. Taubenberger, J. K. et al. Characterization of the 1918 influenza virus polymerase genes. Nature 437, 889-893 (2005).
13. Salomon, R. et al. The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04. J. Exp. Med. 203, 689-697 (2006).
14. Gabriel, G. et al. The viral polymerase mediates adaptation of an avian influenza virus to a mammalian host. Proc. Natl Acad. Sci. USA 102, 18590-18595 (2005).
15. Shinya, K. et al. PB2 amino acid at position 627 affects replicative efficiency, but not cell tropism, of Hong Kong H5N1 influenza A viruses in mice. Virology 320, 258-266 (2004).
16. Hatta, M., Gao, P., Halfmann, P. & Kawaoka, Y. Molecular basis for high virulence of Hong Kong H5N1 influenza A viruses. Science 293, 1840-1842 (2001).
17. Katz, J. M. et al. Molecular correlates of influenza A H5N1 virus pathogenesis in mice. J. Virol. 74, 10807-10810 (2000).
18. Fodor, E. et al. Rescue of influenza A virus from recombinant DNA. J. Virol. 73, 9679-9682 (1999).
19. Hayden, F. G. et al. Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense. J. Clin. Invest. 101, 643-649 (1998).
20. Reid, A. H., Fanning, T. G., Hultin, J. V. & Taubenberger, J. K. Origin and evolution of the 1918 'Spanish' influenza virus hemagglutinin gene. Proc. Natl Acad. Sci. USA 96, 1651-1656 (1999).
21. Reid, A. H., Fanning, T. G., Janczewski, T. A., McCall, S. & Taubenberger, J. K. Characterization of the 1918 'Spanish' influenza virus matrix gene segment. J. Virol. 76, 10717-10723 (2002).
22. Reid, A. H., Fanning, T. G., Janczewski, T. A. & Taubenberger, J. K. Characterization of the 1918 'Spanish' influenza virus neuraminidase gene. Proc. Natl Acad. Sci. USA 97, 6785-6790 (2000).
23. Basler, C. F. et al. Sequence of the 1918 pandemic influenza virus nonstructural gene (NS) segment and characterization of recombinant viruses bearing the 1918 NS genes. Proc. Natl Acad. Sci. USA 98, 2746-2751 (2001).
24. Reid, A. H., Fanning, T. G., Janczewski, T. A., Lourens, R. M. & Taubenberger, J. K. Novel origin of the 1918 pandemic influenza virus nucleoprotein gene. J. Virol. 78, 12462-12470 (2004).
25. Kash, J. C. et al. Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence. J. Virol. 80, 3009-3020 (2006).
26. Brazma, A. et al. Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nature Genet. 29, 365-371 (2001).