A Recombinant Influenza A Virus Expressing an RNA-Binding-Defective NS1 Protein Induces High Levels of Beta Interferon and Is Attenuated in Mice

Journal of Virology

Volumn 77, Issue 24, 2003, Pages 13257-13266

  Donelan, Nicola R ^a   Basler, Christopher F ^a   García Sastre, Adolfo ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; BETA INTERFERON; MUTANT PROTEIN; RNA BINDING PROTEIN; TRANSCRIPTION FACTOR;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; GENE MUTATION; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; RNA BINDING; RNA TRANSLATION; VIRUS CELL INTERACTION; VIRUS EXPRESSION; VIRUS RECOMBINANT; VIRUS VIRULENCE;

ANIMALS; CELL LINE; FEMALE; INFLUENZA A VIRUS; INTERFERON-BETA; MICE; MICE, INBRED BALB C; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS; RECOMBINATION, GENETIC; RNA, DOUBLE-STRANDED; RNA, VIRAL; RNA-BINDING PROTEINS; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE; VIRUS REPLICATION;

EID: 0345167006     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.24.13257-13266.2003     Document Type: Article

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