-
1
-
-
33747422892
-
Brain nicotinic acetylcholine receptors: Native subtypes and their relevance
-
Gotti C, Zoli M, Clementi F. Brain nicotinic acetylcholine receptors: native subtypes and their relevance. Trends Pharmacol Sci 2006; 27: 482-91.
-
(2006)
Trends Pharmacol Sci
, vol.27
, pp. 482-491
-
-
Gotti, C.1
Zoli, M.2
Clementi, F.3
-
2
-
-
33847029091
-
Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
-
Dani JA, Bertrand D. Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annu Rev Pharmacol Toxicol 2007; 47: 699-729.
-
(2007)
Annu Rev Pharmacol Toxicol
, vol.47
, pp. 699-729
-
-
Dani, J.A.1
Bertrand, D.2
-
3
-
-
52049122813
-
Structural answers and persistent questions about how nicotinic receptors work
-
Wells GB. Structural answers and persistent questions about how nicotinic receptors work. Front Biosci 2008; 13: 5479-510.
-
(2008)
Front Biosci
, vol.13
, pp. 5479-5510
-
-
Wells, G.B.1
-
4
-
-
40549109577
-
Basic and clinical aspects of non-neuronal acetylcholine: Biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors
-
Grando SA. Basic and clinical aspects of non-neuronal acetylcholine: biological and clinical significance of non-canonical ligands of epithelial nicotinic acetylcholine receptors. J Pharmacol Sci 2008; 106: 174-9.
-
(2008)
J Pharmacol Sci
, vol.106
, pp. 174-179
-
-
Grando, S.A.1
-
7
-
-
0018363612
-
Conformational studies of neurotoxin II from Naja naja oxiana. Selective N-acylation, circular dichroism and nuclear-magnetic-resonance study of acylation products
-
Tsetlin VI, Arseniev AS, Utkin YN, Gurevich AZ, Senyavina LB, Bystrov VF, et al. Conformational studies of neurotoxin II from Naja naja oxiana. Selective N-acylation, circular dichroism and nuclear-magnetic-resonance study of acylation products. Eur J Biochem 1979; 94: 337-46.
-
(1979)
Eur J Biochem
, vol.94
, pp. 337-346
-
-
Tsetlin, V.I.1
Arseniev, A.S.2
Utkin, Y.N.3
Gurevich, A.Z.4
Senyavina, L.B.5
Bystrov, V.F.6
-
8
-
-
0020064794
-
Specific binding to isolated acetylcholine receptor of a synthetic peptide duplicating the sequence of the presumed active center of a lethal toxin from snake venom
-
Juillerat MA, Schwendimann B, Hauert J, Fulpius BW, Bargetzi JP. Specific binding to isolated acetylcholine receptor of a synthetic peptide duplicating the sequence of the presumed active center of a lethal toxin from snake venom. J Biol Chem 1982; 257: 2901-7.
-
(1982)
J Biol Chem
, vol.257
, pp. 2901-2907
-
-
Juillerat, M.A.1
Schwendimann, B.2
Hauert, J.3
Fulpius, B.W.4
Bargetzi, J.P.5
-
9
-
-
0025885773
-
Structure-function relationship of lapemis toxin: A synthetic approach
-
Miller RA, Tu AT. Structure-function relationship of lapemis toxin: A synthetic approach. Arch Biochem Biophys 1991; 29: 69-75.
-
(1991)
Arch Biochem Biophys
, vol.29
, pp. 69-75
-
-
Miller, R.A.1
Tu, A.T.2
-
10
-
-
0026335859
-
Structure-function relationships of curaremimetic neurotoxin loop 2 and of a structurally similar segment of rabies virus glycoprotein in their interaction with the nicotinic acetylcholine receptor
-
Lentz TL. Structure-function relationships of curaremimetic neurotoxin loop 2 and of a structurally similar segment of rabies virus glycoprotein in their interaction with the nicotinic acetylcholine receptor. Biochemistry 1991; 30: 10949-57.
-
(1991)
Biochemistry
, vol.30
, pp. 10949-10957
-
-
Lentz, T.L.1
-
11
-
-
0025601773
-
Immunization with a peptide having both T cell and conformationally restricted B cell epitopes elicits neutralizing antisera against a snake neurotoxin
-
Léonetti M, Pillet L, Maillere B, Lamthanh H, Frachon P, Couderc J, et al. Immunization with a peptide having both T cell and conformationally restricted B cell epitopes elicits neutralizing antisera against a snake neurotoxin. J Immunol 1990; 145: 4214-21.
-
(1990)
J Immunol
, vol.145
, pp. 4214-4221
-
-
Léonetti, M.1
Pillet, L.2
Maillere, B.3
Lamthanh, H.4
Frachon, P.5
Couderc, J.6
-
12
-
-
0021678943
-
Amino acid sequence similarity between rabies virus glycoprotein and snake venom curaremimetic neurotoxins
-
Lentz TL, Wilson PT, Hawrot E, Speicher DW. Amino acid sequence similarity between rabies virus glycoprotein and snake venom curaremimetic neurotoxins. Science 1984; 226: 847-8.
-
(1984)
Science
, vol.226
, pp. 847-848
-
-
Lentz, T.L.1
Wilson, P.T.2
Hawrot, E.3
Speicher, D.W.4
-
13
-
-
0023711641
-
Synthetic peptides in the study of the interaction of rabies virus and the acetylcholine receptor
-
Lentz TL, Hawrot E, Donnelly-Roberts D, Wilson PT. Synthetic peptides in the study of the interaction of rabies virus and the acetylcholine receptor. Adv Biochem Psychopharmacol 1988; 44: 57-71.
-
(1988)
Adv Biochem Psychopharmacol
, vol.44
, pp. 57-71
-
-
Lentz, T.L.1
Hawrot, E.2
Donnelly-Roberts, D.3
Wilson, P.T.4
-
14
-
-
0020042226
-
Is the acetylcholine receptor a rabies virus receptor?
-
Lentz TL, Burrage TG, Smith AL, Crick J, Tignor GH. Is the acetylcholine receptor a rabies virus receptor? Science.1982; 215: 182-4.
-
(1982)
Science
, vol.215
, pp. 182-184
-
-
Lentz, T.L.1
Burrage, T.G.2
Smith, A.L.3
Crick, J.4
Tignor, G.H.5
-
15
-
-
0022857630
-
Binding of rabies virus to purified Torpedo acetylcholine receptor
-
Lentz TL, Benson RJ, Klimowicz D, Wilson PT, Hawrot E. Binding of rabies virus to purified Torpedo acetylcholine receptor. Brain Res 1986; 387: 211-9.
-
(1986)
Brain Res
, vol.387
, pp. 211-219
-
-
Lentz, T.L.1
Benson, R.J.2
Klimowicz, D.3
Wilson, P.T.4
Hawrot, E.5
-
16
-
-
0023613528
-
Synthetic peptides corresponding to sequences of snake venom neurotoxins and rabies virus glycoprotein bind to the nicotinic acetylcholine receptor
-
Lentz TL, Hawrot E, Wilson PT. Synthetic peptides corresponding to sequences of snake venom neurotoxins and rabies virus glycoprotein bind to the nicotinic acetylcholine receptor. Proteins 1987; 2: 298-307.
-
(1987)
Proteins
, vol.2
, pp. 298-307
-
-
Lentz, T.L.1
Hawrot, E.2
Wilson, P.T.3
-
17
-
-
0024655992
-
Synthetic peptides of neurotoxins and rabies virus glycoprotein behave as antagonists in a functional assay for the acetylcholine receptor
-
Donnelly-Roberts DL, Lentz TL. Synthetic peptides of neurotoxins and rabies virus glycoprotein behave as antagonists in a functional assay for the acetylcholine receptor. Pept Res 1989; 2: 221-6.
-
(1989)
Pept Res
, vol.2
, pp. 221-226
-
-
Donnelly-Roberts, D.L.1
Lentz, T.L.2
-
18
-
-
0025766858
-
Structural and conformational similarity between synthetic peptides of curaremimetic neurotoxins and rabies virus glycoprotein
-
Donnelly-Roberts DL, Lentz TL. Structural and conformational similarity between synthetic peptides of curaremimetic neurotoxins and rabies virus glycoprotein. Brain Res Mol Brain Res 1991; 11: 107-13.
-
(1991)
Brain Res Mol Brain Res
, vol.11
, pp. 107-113
-
-
Donnelly-Roberts, D.L.1
Lentz, T.L.2
-
19
-
-
0024723471
-
A monoclonal antibody to a synthetic fragment of rabies virus glycoprotein binds ligands of the nicotinic cholinergic receptor
-
Rustici M, Santucci A, Lozzi L, Petreni S, Spreafico A, Neri P, et al. A monoclonal antibody to a synthetic fragment of rabies virus glycoprotein binds ligands of the nicotinic cholinergic receptor. J Mol Recognit 1989; 2: 51-5.
-
(1989)
J Mol Recognit
, vol.2
, pp. 51-55
-
-
Rustici, M.1
Santucci, A.2
Lozzi, L.3
Petreni, S.4
Spreafico, A.5
Neri, P.6
-
20
-
-
0037020152
-
Rabies virus glycoprotein (RVG) is a trimeric ligand for the N-terminal cysteine-rich domain of the mammalian p75 neurotrophin receptor
-
Langevin C, Jaaro H, Bressanelli S, Fainzilber M, Tuffereau C. Rabies virus glycoprotein (RVG) is a trimeric ligand for the N-terminal cysteine-rich domain of the mammalian p75 neurotrophin receptor. J Biol Chem 2002; 277: 37655-62.
-
(2002)
J Biol Chem
, vol.277
, pp. 37655-37662
-
-
Langevin, C.1
Jaaro, H.2
Bressanelli, S.3
Fainzilber, M.4
Tuffereau, C.5
-
21
-
-
16244414899
-
Rabies virus receptors
-
Lafon M. Rabies virus receptors. J Neurovirol 2005; 11: 82-7.
-
(2005)
J Neurovirol
, vol.11
, pp. 82-87
-
-
Lafon, M.1
-
22
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
Kumar P, Wu H, McBride JL, Jung KE, Kim MH, Davidson BL, et al. Transvascular delivery of small interfering RNA to the central nervous system. Nature 2007; 448: 39-43.
-
(2007)
Nature
, vol.448
, pp. 39-43
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
Jung, K.E.4
Kim, M.H.5
Davidson, B.L.6
-
23
-
-
0025028790
-
Sequence homology between HIV gp120, rabies virus glycoprotein, and snake venom neurotoxins. Is the nicotinic acetylcholine receptor an HIV receptor?
-
Neri P, Bracci L, Rustici M, Santucci A. Sequence homology between HIV gp120, rabies virus glycoprotein, and snake venom neurotoxins. Is the nicotinic acetylcholine receptor an HIV receptor? Arch Virol 1990; 114: 265-9.
-
(1990)
Arch Virol
, vol.114
, pp. 265-269
-
-
Neri, P.1
Bracci, L.2
Rustici, M.3
Santucci, A.4
-
24
-
-
0030822348
-
Molecular mimicry between the rabies virus glycoprotein and human immunodeficiency virus-1 GP120: Cross-reacting antibodies induced by rabies vaccination
-
Bracci L, Ballas SK, Spreafico A, Neri P. Molecular mimicry between the rabies virus glycoprotein and human immunodeficiency virus-1 GP120: cross-reacting antibodies induced by rabies vaccination. Blood 1997; 90: 3623-8.
-
(1997)
Blood
, vol.90
, pp. 3623-3628
-
-
Bracci, L.1
Ballas, S.K.2
Spreafico, A.3
Neri, P.4
-
25
-
-
49549112067
-
Potentiation of HIV-1 expression in microglial cells by nicotine: Involvement of transforming growth factor-β1
-
Rock RB, Gekker G, Aravalli RN, Hu S, Sheng WS, Peterson PK. Potentiation of HIV-1 expression in microglial cells by nicotine: involvement of transforming growth factor-β1. J Neuroimmune Pharmacol 2008; 3: 143-9.
-
(2008)
J Neuroimmune Pharmacol
, vol.3
, pp. 143-149
-
-
Rock, R.B.1
Gekker, G.2
Aravalli, R.N.3
Hu, S.4
Sheng, W.S.5
Peterson, P.K.6
-
26
-
-
0026098338
-
Structural homology between hemagglutinin (HA) of measles virus and the active site of long neurotoxins
-
Yoshikawa Y, Yamanouchi K, Takasu T, Rauf S, Ahmed A. Structural homology between hemagglutinin (HA) of measles virus and the active site of long neurotoxins. Virus Genes 1991; 5: 57-67.
-
(1991)
Virus Genes
, vol.5
, pp. 57-67
-
-
Yoshikawa, Y.1
Yamanouchi, K.2
Takasu, T.3
Rauf, S.4
Ahmed, A.5
-
27
-
-
0037662714
-
Identification of regions involved in the binding of α-Bgt to the human α7 neuronal nicotinic acetylcholine receptor using synthetic peptides
-
Marinou M, Tzartos SJ. Identification of regions involved in the binding of α-Bgt to the human α7 neuronal nicotinic acetylcholine receptor using synthetic peptides. Biochem J 2003; 372: 543-54.
-
(2003)
Biochem J
, vol.372
, pp. 543-554
-
-
Marinou, M.1
Tzartos, S.J.2
-
28
-
-
0023657230
-
Profile of the α-bungarotoxin-binding regions on the extracellular part of the α-chain of Torpedo californica acetylcholine receptor
-
Mulac-Jericevic B, Atassi MZ. Profile of the α-bungarotoxin-binding regions on the extracellular part of the α-chain of Torpedo californica acetylcholine receptor. Biochem J 1987; 248: 847-52.
-
(1987)
Biochem J
, vol.248
, pp. 847-852
-
-
Mulac-Jericevic, B.1
Atassi, M.Z.2
-
29
-
-
0029242872
-
Fragments 183-198 and 125-145 of the α-subunits of the Torpedo californica nicotinic acetylcholinergic receptor binds α-bungarotoxin and neurotoxin II from Naja naja oxiana
-
Klukas O, Peshenko IA, Rodionov IL, Teliakova OV, Utkin IuN, Tsetlin VI. Fragments 183-198 and 125-145 of the α-subunits of the Torpedo californica nicotinic acetylcholinergic receptor binds α-bungarotoxin and neurotoxin II from Naja naja oxiana. Bioorg Khim 1995; 21: 152-5.
-
(1995)
Bioorg Khim
, vol.21
, pp. 152-155
-
-
Klukas, O.1
Peshenko, I.A.2
Rodionov, I.L.3
Teliakova, O.V.4
Utkin, I.N.5
Tsetlin, V.I.6
-
30
-
-
1642450641
-
Snake and snail toxins acting on nicotinic acetylcholine receptors: Fundamental aspects and medical applications
-
Tsetlin VI, Hucho F. Snake and snail toxins acting on nicotinic acetylcholine receptors: Fundamental aspects and medical applications. FEBS Lett 2004; 557: 9-13.
-
(2004)
FEBS Lett
, vol.557
, pp. 9-13
-
-
Tsetlin, V.I.1
Hucho, F.2
-
31
-
-
1042268143
-
Three-finger α-neurotoxins and the nicotinic acetylcholine receptor, forty years on
-
Nirthanan S, Gwee MC. Three-finger α-neurotoxins and the nicotinic acetylcholine receptor, forty years on. J Pharmacol Sci 2004; 94: 1-17.
-
(2004)
J Pharmacol Sci
, vol.94
, pp. 1-17
-
-
Nirthanan, S.1
Gwee, M.C.2
-
32
-
-
18444411922
-
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors
-
Bourne Y, Talley TT, Hansen SB, Taylor P, Marchot P. Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake α-neurotoxins and nicotinic receptors. EMBO J 2005; 24: 1512-22
-
(2005)
EMBO J
, vol.24
, pp. 1512-1522
-
-
Bourne, Y.1
Talley, T.T.2
Hansen, S.B.3
Taylor, P.4
Marchot, P.5
-
33
-
-
34547520128
-
Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution
-
Dellisanti CD, Yao Y, Stroud JC, Wang ZZ, Chen L. Crystal structure of the extracellular domain of nAChR α1 bound to α-bungarotoxin at 1.94 Å resolution. Nat Neurosci 2007; 10: 953-62.
-
(2007)
Nat Neurosci
, vol.10
, pp. 953-962
-
-
Dellisanti, C.D.1
Yao, Y.2
Stroud, J.C.3
Wang, Z.Z.4
Chen, L.5
-
34
-
-
0020552691
-
Substance P modulates the sensitivity of the nicotinic receptor in amphibian cholinergic transmission
-
Akasu T, Kojima M, Koketsu K. Substance P modulates the sensitivity of the nicotinic receptor in amphibian cholinergic transmission. Br J Pharmacol 1983; 80: 123-31.
-
(1983)
Br J Pharmacol
, vol.80
, pp. 123-131
-
-
Akasu, T.1
Kojima, M.2
Koketsu, K.3
-
35
-
-
0023501114
-
Effects of substance P on the binding of ligands to nicotinic acetylcholine receptors
-
Weiland GA, Durkin JA, Henley JM, Simasko SM. Effects of substance P on the binding of ligands to nicotinic acetylcholine receptors. Mol Pharmacol 1987; 32: 625-32.
-
(1987)
Mol Pharmacol
, vol.32
, pp. 625-632
-
-
Weiland, G.A.1
Durkin, J.A.2
Henley, J.M.3
Simasko, S.M.4
-
36
-
-
0027195558
-
Effects of substance P on the binding of agonists to the nicotinic acetylcholine receptor of Torpedo electroplaque
-
Min CK, Weiland GA. Effects of substance P on the binding of agonists to the nicotinic acetylcholine receptor of Torpedo electroplaque. J Neurochem 1993; 60: 2238-46.
-
(1993)
J Neurochem
, vol.60
, pp. 2238-2246
-
-
Min, C.K.1
Weiland, G.A.2
-
37
-
-
0028350789
-
The β subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition
-
Stafford GA, Oswald RE, Weiland GA. The β subunit of neuronal nicotinic acetylcholine receptors is a determinant of the affinity for substance P inhibition. Mol Pharmacol 1994; 45: 758-62.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 758-762
-
-
Stafford, G.A.1
Oswald, R.E.2
Weiland, G.A.3
-
38
-
-
0032423597
-
Two domains of the β subunit of neuronal nicotinic acetylcholine receptors contribute to the affinity of substance P
-
Stafford GA, Oswald RE, Figl A, Cohen BN, Weiland GA. Two domains of the β subunit of neuronal nicotinic acetylcholine receptors contribute to the affinity of substance P. J Pharmacol Exp Ther 1998; 286: 619-26.
-
(1998)
J Pharmacol Exp Ther
, vol.286
, pp. 619-626
-
-
Stafford, G.A.1
Oswald, R.E.2
Figl, A.3
Cohen, B.N.4
Weiland, G.A.5
-
39
-
-
0028177101
-
Characterization of the binding of [3H]substance P to the nicotinic acetylcholine receptor of Torpedo electroplaque
-
Min CK, Owens J, Weiland GA. Characterization of the binding of [3H]substance P to the nicotinic acetylcholine receptor of Torpedo electroplaque. Mol Pharmacol 1994; 45: 221-7.
-
(1994)
Mol Pharmacol
, vol.45
, pp. 221-227
-
-
Min, C.K.1
Owens, J.2
Weiland, G.A.3
-
40
-
-
0028585937
-
Agonist-induced photoincorporation of a p-benzoylphenylalanine derivative of substance P into membrane-spanning region 2 of the Torpedo nicotinic acetylcholine receptor δ subunit
-
Blanton MP, Li YM, Stimson ER, Maggio JE, Cohen JB. Agonist-induced photoincorporation of a p-benzoylphenylalanine derivative of substance P into membrane-spanning region 2 of the Torpedo nicotinic acetylcholine receptor δ subunit. Mol Pharmacol 1994; 46: 1048-55.
-
(1994)
Mol Pharmacol
, vol.46
, pp. 1048-1055
-
-
Blanton, M.P.1
Li, Y.M.2
Stimson, E.R.3
Maggio, J.E.4
Cohen, J.B.5
-
41
-
-
0030733559
-
Substance P derivatives with photoactivatable labels in the N-terminal part of the molecule
-
Kasheverov IE, Utkin YN, Franke P, Tsetlin VI. Substance P derivatives with photoactivatable labels in the N-terminal part of the molecule. J Pept Res 1997; 50: 408-14.
-
(1997)
J Pept Res
, vol.50
, pp. 408-414
-
-
Kasheverov, I.E.1
Utkin, Y.N.2
Franke, P.3
Tsetlin, V.I.4
-
42
-
-
0030803637
-
Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist
-
Mahata SK, O'Connor DT, Mahata M, Yoo SH, Taupenot L, Wu H, et al. Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist. Clin Invest 1997; 100: 1623-33.
-
(1997)
Clin Invest
, vol.100
, pp. 1623-1633
-
-
Mahata, S.K.1
O'Connor, D.T.2
Mahata, M.3
Yoo, S.H.4
Taupenot, L.5
Wu, H.6
-
43
-
-
0034711579
-
Interaction of the catecholamine release-inhibitory peptide catestatin (human chromogranin A(352-372)) with the chromaffin cell surface and Torpedo electroplax: Implications for nicotinic cholinergic antagonism
-
Taupenot L, Mahata SK, Mahata M, Parmer RJ, O'Connor DT. Interaction of the catecholamine release-inhibitory peptide catestatin (human chromogranin A(352-372)) with the chromaffin cell surface and Torpedo electroplax: Implications for nicotinic cholinergic antagonism. Regul Pept 2000; 95: 9-17.
-
(2000)
Regul Pept
, vol.95
, pp. 9-17
-
-
Taupenot, L.1
Mahata, S.K.2
Mahata, M.3
Parmer, R.J.4
O'Connor, D.T.5
-
44
-
-
0037080157
-
Modulatory mechanism of the endogenous peptide catestatin on neuronal nicotinic acetylcholine receptors and exocytosis
-
Herrero CJ, Alés E, Pintado AJ, López MG, García-Palomero E, Mahata SK, et al. Modulatory mechanism of the endogenous peptide catestatin on neuronal nicotinic acetylcholine receptors and exocytosis. J Neurosci 2002; 22: 377-88.
-
(2002)
J Neurosci
, vol.22
, pp. 377-388
-
-
Herrero, C.J.1
Alés, E.2
Pintado, A.J.3
López, M.G.4
García-Palomero, E.5
Mahata, S.K.6
-
45
-
-
31144444166
-
Apolipoprotein E-derived peptides block α7 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes
-
Gay EA, Klein RC, Yakel JL. Apolipoprotein E-derived peptides block α7 neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Pharmacol Exp Ther 2006; 316: 835-42.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 835-842
-
-
Gay, E.A.1
Klein, R.C.2
Yakel, J.L.3
-
46
-
-
34748837826
-
Structural determinates for apolipoprotein E-derived peptide interaction with the α7 nicotinic acetylcholine receptor
-
Gay EA, Bienstock RJ, Lamb PW, Yakel JL. Structural determinates for apolipoprotein E-derived peptide interaction with the α7 nicotinic acetylcholine receptor. Mol Pharmacol 2007; 72: 838-49.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 838-849
-
-
Gay, E.A.1
Bienstock, R.J.2
Lamb, P.W.3
Yakel, J.L.4
-
47
-
-
0036142564
-
A novel class of peptides with facilitating action on neuronal nicotinic receptors of rat chromaffin cells in vitro: Functional and molecular dynamics studies
-
Di Angelantonio S, Costa V, Carloni P, Messori L, Nistri A. A novel class of peptides with facilitating action on neuronal nicotinic receptors of rat chromaffin cells in vitro: Functional and molecular dynamics studies. Mol Pharmacol 2002; 61: 43-54.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 43-54
-
-
Di Angelantonio, S.1
Costa, V.2
Carloni, P.3
Messori, L.4
Nistri, A.5
-
48
-
-
0034006944
-
β-Amyloid(1-42) binds to α7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology
-
Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB. β-Amyloid(1-42) binds to α7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology. J Biol Chem 2000; 275: 5626-32.
-
(2000)
J Biol Chem
, vol.275
, pp. 5626-5632
-
-
Wang, H.Y.1
Lee, D.H.2
D'Andrea, M.R.3
Peterson, P.A.4
Shank, R.P.5
Reitz, A.B.6
-
49
-
-
34547667083
-
β-amyloid peptide - nicotinic acetylcholine receptor interaction: The two faces of health and disease
-
Dineley KT. β-amyloid peptide - nicotinic acetylcholine receptor interaction: The two faces of health and disease. Front Biosci 2007; 12: 5030-8.
-
(2007)
Front Biosci
, vol.12
, pp. 5030-5038
-
-
Dineley, K.T.1
-
50
-
-
0033624509
-
Amyloid peptide Aβ(1-42) binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors
-
Wang HY, Lee DH, Davis CB, Shank RP. Amyloid peptide Aβ(1-42) binds selectively and with picomolar affinity to α7 nicotinic acetylcholine receptors. J Neurochem 2000; 75: 1155-61.
-
(2000)
J Neurochem
, vol.75
, pp. 1155-1161
-
-
Wang, H.Y.1
Lee, D.H.2
Davis, C.B.3
Shank, R.P.4
-
51
-
-
0037067717
-
β-Amyloid peptide activates α 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes
-
Dineley KT, Bell KA, Bui D, Sweatt JD. β-Amyloid peptide activates α 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes. J Biol Chem 2002; 277: 25056-61.
-
(2002)
J Biol Chem
, vol.277
, pp. 25056-25061
-
-
Dineley, K.T.1
Bell, K.A.2
Bui, D.3
Sweatt, J.D.4
-
52
-
-
0242593724
-
β-amyloid peptide activates non-α7 nicotinic acetylcholine receptors in rat basal forebrain neurons
-
Fu W, Jhamandas JH. β-amyloid peptide activates non-α7 nicotinic acetylcholine receptors in rat basal forebrain neurons. J Neurophysiol 2003; 90: 3130-6.
-
(2003)
J Neurophysiol
, vol.90
, pp. 3130-3136
-
-
Fu, W.1
Jhamandas, J.H.2
-
53
-
-
4444222165
-
β-Amyloid directly inhibits human α4β2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells
-
Wu J, Kuo YP, George AA, Xu L, Hu J, Lukas RJ. β-Amyloid directly inhibits human α4β2-nicotinic acetylcholine receptors heterologously expressed in human SH-EP1 cells. J Biol Chem 2004; 279: 37842-51.
-
(2004)
J Biol Chem
, vol.279
, pp. 37842-37851
-
-
Wu, J.1
Kuo, Y.P.2
George, A.A.3
Xu, L.4
Hu, J.5
Lukas, R.J.6
-
54
-
-
28444467395
-
Subtype-specific actions of β-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (α7, α4β2, α3β4) expressed in Xenopus laevis oocytes
-
Pym L, Kemp M, Raymond-Delpech V, Buckingham S, Boyd CA, et al. Subtype-specific actions of β-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (α7, α4β2, α3β4) expressed in Xenopus laevis oocytes. Br J Pharmacol 2005; 146: 964-71.
-
(2005)
Br J Pharmacol
, vol.146
, pp. 964-971
-
-
Pym, L.1
Kemp, M.2
Raymond-Delpech, V.3
Buckingham, S.4
Boyd, C.A.5
-
55
-
-
35348945928
-
The Aβ1-42M35C mutated amyloid peptide Aβ1-42 and the 25-35 fragment fail to mimic the subtype-specificity of actions on recombinant human nicotinic acetylcholine receptors (α7, α4β2, α3β4)
-
Pym LJ, Buckingham SD, Tsetlin V, Boyd CA, Sattelle DB. The Aβ1-42M35C mutated amyloid peptide Aβ1-42 and the 25-35 fragment fail to mimic the subtype-specificity of actions on recombinant human nicotinic acetylcholine receptors (α7, α4β2, α3β4). Neurosci Lett 2007; 427: 28-33.
-
(2007)
Neurosci Lett
, vol.427
, pp. 28-33
-
-
Pym, L.J.1
Buckingham, S.D.2
Tsetlin, V.3
Boyd, C.A.4
Sattelle, D.B.5
-
56
-
-
34249823327
-
The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor
-
Small DH, Maksel D, Kerr ML, Ng J, Hou X, Chu C, et al. The β-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the α7 nicotinic acetylcholine receptor. J Neurochem 2007; 101: 1527-38.
-
(2007)
J Neurochem
, vol.101
, pp. 1527-1538
-
-
Small, D.H.1
Maksel, D.2
Kerr, M.L.3
Ng, J.4
Hou, X.5
Chu, C.6
-
57
-
-
24744442787
-
Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid β
-
Magdesian MH, Nery AA, Martins AH, Juliano MA, Juliano L, Ulrich H, et al. Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid β. J Biol Chem 2005; 280: 31085-90.
-
(2005)
J Biol Chem
, vol.280
, pp. 31085-31090
-
-
Magdesian, M.H.1
Nery, A.A.2
Martins, A.H.3
Juliano, M.A.4
Juliano, L.5
Ulrich, H.6
-
58
-
-
33646842340
-
Fully flexible docking models of the complex between α7 nicotinic receptor avd a potent heptapeptide inhibitor of the β-amyloid peptide binding
-
Espinoza-Fonseca LM, Trujillo-Ferrara JG. Fully flexible docking models of the complex between α7 nicotinic receptor avd a potent heptapeptide inhibitor of the β-amyloid peptide binding. Bioorg Med Chem Lett 2006; 16: 3519-23.
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 3519-3523
-
-
Espinoza-Fonseca, L.M.1
Trujillo-Ferrara, J.G.2
-
59
-
-
4644255704
-
Molecular docking of four β-amyloid1-42 fragments on the α7 nicotinic receptor: Delineating the binding site of the Aβ peptides
-
Espinoza-Fonseca LM. Molecular docking of four β-amyloid1-42 fragments on the α7 nicotinic receptor: Delineating the binding site of the Aβ peptides. Biochem Biophys Res Commun 2004; 323: 1191-6.
-
(2004)
Biochem Biophys Res Commun
, vol.323
, pp. 1191-1196
-
-
Espinoza-Fonseca, L.M.1
-
60
-
-
0242694942
-
Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation
-
Stevens TR, Krueger SR, Fitzsimonds RM, Picciotto MP. Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation. J Neurosci 2003; 23: 10093-9.
-
(2003)
J Neurosci
, vol.23
, pp. 10093-10099
-
-
Stevens, T.R.1
Krueger, S.R.2
Fitzsimonds, R.M.3
Picciotto, M.P.4
-
61
-
-
0346460961
-
Janus kinase 2, an early target of α 7 nicotinic acetylcholine receptor-mediated neuroprotection against Aβ-(1-42) amyloid
-
Shaw S, Bencherif M, Marrero MB. Janus kinase 2, an early target of α 7 nicotinic acetylcholine receptor-mediated neuroprotection against Aβ-(1-42) amyloid. J Biol Chem 2002; 277: 44920-4.
-
(2002)
J Biol Chem
, vol.277
, pp. 44920-44924
-
-
Shaw, S.1
Bencherif, M.2
Marrero, M.B.3
-
62
-
-
0028944021
-
Effects of waglerin-I on neuromuscular transmission of mouse nerve-muscle preparations
-
Tsai MC, Hsieh WH, Smith LA, Lee CY. Effects of waglerin-I on neuromuscular transmission of mouse nerve-muscle preparations. Toxicon 1995; 33: 363-71.
-
(1995)
Toxicon
, vol.33
, pp. 363-371
-
-
Tsai, M.C.1
Hsieh, W.H.2
Smith, L.A.3
Lee, C.Y.4
-
63
-
-
0028984227
-
Structure-function studies of waglerin I, a lethal peptide from the venom of Wagler's pit viper, Trimeresurus wagleri
-
Schmidt JJ, Weinstein SA. Structure-function studies of waglerin I, a lethal peptide from the venom of Wagler's pit viper, Trimeresurus wagleri. Toxicon 1995; 33: 1043-9.
-
(1995)
Toxicon
, vol.33
, pp. 1043-1049
-
-
Schmidt, J.J.1
Weinstein, S.A.2
-
64
-
-
0030029475
-
Determination of three-dimensional solution structure of waglerin I, a toxin from Trimeresurus wagleri, using 2D-NMR and molecular dynamics simulation
-
Chuang LC, Yu HM, Chen C, Huang TH, Wu SH, Wang KT. Determination of three-dimensional solution structure of waglerin I, a toxin from Trimeresurus wagleri, using 2D-NMR and molecular dynamics simulation. Biochim Biophys Acta 1996; 1292: 145-55.
-
(1996)
Biochim Biophys Acta
, vol.1292
, pp. 145-155
-
-
Chuang, L.C.1
Yu, H.M.2
Chen, C.3
Huang, T.H.4
Wu, S.H.5
Wang, K.T.6
-
65
-
-
0030051866
-
Conformational analysis of a toxic peptide from Trimeresurus wagleri which blocks the nicotinic acetylcholine receptor
-
Sellin LC, Mattila K, Annila A, Schmidt JJ, McArdle JJ, Hyvönen M, et al. Conformational analysis of a toxic peptide from Trimeresurus wagleri which blocks the nicotinic acetylcholine receptor. Biophys J 1996; 70: 3-13.
-
(1996)
Biophys J
, vol.70
, pp. 3-13
-
-
Sellin, L.C.1
Mattila, K.2
Annila, A.3
Schmidt, J.J.4
McArdle, J.J.5
Hyvönen, M.6
-
66
-
-
0030567965
-
Protein engineering of venom toxins by synthetic approach and NMR dynamic simulation: Status of basic amino acid residues in waglerin I
-
Hsiao YM, Chuang CC, Chuang LC, Yu HM, Wang KT, Chiou SH, et al. Protein engineering of venom toxins by synthetic approach and NMR dynamic simulation: Status of basic amino acid residues in waglerin I. Biochem Biophys Res Commun 1996; 227: 59-63.
-
(1996)
Biochem Biophys Res Commun
, vol.227
, pp. 59-63
-
-
Hsiao, Y.M.1
Chuang, C.C.2
Chuang, L.C.3
Yu, H.M.4
Wang, K.T.5
Chiou, S.H.6
-
67
-
-
0032892706
-
Waglerin-1 selectively blocks the ε form of the muscle nicotinic acetylcholine receptor
-
McArdle JJ, Lentz TL, Witzemann V, Schwarz H, Weinstein SA, Schmidt JJ. Waglerin-1 selectively blocks the ε form of the muscle nicotinic acetylcholine receptor. J Pharmacol Exp Ther 1999; 289: 543-50.
-
(1999)
J Pharmacol Exp Ther
, vol.289
, pp. 543-550
-
-
McArdle, J.J.1
Lentz, T.L.2
Witzemann, V.3
Schwarz, H.4
Weinstein, S.A.5
Schmidt, J.J.6
-
68
-
-
0028935519
-
A study on the cause of death due to waglerin-I, a toxin from Trimeresurus wagleri
-
Lin WW, Smith LA, Lee CY. A study on the cause of death due to waglerin-I, a toxin from Trimeresurus wagleri. Toxicon 1995; 33: 111-4.
-
(1995)
Toxicon
, vol.33
, pp. 111-114
-
-
Lin, W.W.1
Smith, L.A.2
Lee, C.Y.3
-
69
-
-
0037085479
-
Identification of residues at the α and ε subunit interfaces mediating specieσ selectivity of Waglerin-1 for nicotinic acetylcholine receptors
-
Molles BE, Rezai P, Kline EF, McArdle JJ, Sine SM, Taylor P. Identification of residues at the α and ε subunit interfaces mediating specieσ selectivity of Waglerin-1 for nicotinic acetylcholine receptors. J Biol Chem 2002; 277: 5433-40.
-
(2002)
J Biol Chem
, vol.277
, pp. 5433-5440
-
-
Molles, B.E.1
Rezai, P.2
Kline, E.F.3
McArdle, J.J.4
Sine, S.M.5
Taylor, P.6
-
70
-
-
0037172669
-
Residues in the ε subunit of the nicotinic acetylcholine receptor interact to confer selectivity of waglerin-1 for the α-ε subunit interface site
-
Molles BE, Tsigelny I, Nguyen PD, Gao SX, Sine SM, Taylor P. Residues in the ε subunit of the nicotinic acetylcholine receptor interact to confer selectivity of waglerin-1 for the α-ε subunit interface site. Biochemistry 2002; 41: 7895-906.
-
(2002)
Biochemistry
, vol.41
, pp. 7895-7906
-
-
Molles, B.E.1
Tsigelny, I.2
Nguyen, P.D.3
Gao, S.X.4
Sine, S.M.5
Taylor, P.6
-
71
-
-
33751049816
-
Conotoxins down under
-
Norton RS, Olivera BM. Conotoxins down under. Toxicon 2006; 48: 780-98.
-
(2006)
Toxicon
, vol.48
, pp. 780-798
-
-
Norton, R.S.1
Olivera, B.M.2
-
72
-
-
0347989461
-
Conus venoms: A rich source of novel ion channel-targeted peptides
-
Terlau H, Olivera BM. Conus venoms: A rich source of novel ion channel-targeted peptides. Physiol Rev 2004; 84: 41-68.
-
(2004)
Physiol Rev
, vol.84
, pp. 41-68
-
-
Terlau, H.1
Olivera, B.M.2
-
73
-
-
3042606237
-
α-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes
-
Nicke A, Wonnacott S, Lewis RJ. α-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes. Eur J Biochem 2004; 271: 2305-19.
-
(2004)
Eur J Biochem
, vol.271
, pp. 2305-2319
-
-
Nicke, A.1
Wonnacott, S.2
Lewis, R.J.3
-
74
-
-
18744413004
-
α-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses
-
Janes RW. α-Conotoxins as selective probes for nicotinic acetylcholine receptor subclasses. Curr Opin Pharmacol 2005; 5: 280-92.
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 280-292
-
-
Janes, R.W.1
-
75
-
-
38849170998
-
α4/3 Conotoxins: Phylogenetic distribution, functional properties, and structure-function insights
-
Ellison M, Olivera BM. α4/3 Conotoxins: Phylogenetic distribution, functional properties, and structure-function insights. Chem Rec 2007; 7: 341-53.
-
(2007)
Chem Rec
, vol.7
, pp. 341-353
-
-
Ellison, M.1
Olivera, B.M.2
-
76
-
-
33750957742
-
Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor
-
Livett BG, Sandall DW, Keays D, Down J, Gayler KR, Satkunanathan N, et al. Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor. Toxicon 2006; 48: 810-29.
-
(2006)
Toxicon
, vol.48
, pp. 810-829
-
-
Livett, B.G.1
Sandall, D.W.2
Keays, D.3
Down, J.4
Gayler, K.R.5
Satkunanathan, N.6
-
77
-
-
17344374881
-
A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom
-
Shon KJ, Grilley M, Jacobsen R, Cartier GE, Hopkins C, Gray WR, et al. A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom. Biochemistry 1997; 36: 9581-7.
-
(1997)
Biochemistry
, vol.36
, pp. 9581-9587
-
-
Shon, K.J.1
Grilley, M.2
Jacobsen, R.3
Cartier, G.E.4
Hopkins, C.5
Gray, W.R.6
-
78
-
-
0038348783
-
An improved solution structure for Ψ-conotoxin PIIIE
-
Van Wagoner RM, Ireland CM. An improved solution structure for Ψ-conotoxin PIIIE. Biochemistry 2003; 42: 6347-52.
-
(2003)
Biochemistry
, vol.42
, pp. 6347-6352
-
-
Van Wagoner, R.M.1
Ireland, C.M.2
-
79
-
-
0038010721
-
Characterization and three-dimensional structure determination of Ψ-conotoxin PIIIF, a novel noncompetitive antagonist of nicotinic acetylcholine receptors
-
Van Wagoner RM, Jacobsen RB, Olivera BM, Ireland CM. Characterization and three-dimensional structure determination of Ψ-conotoxin PIIIF, a novel noncompetitive antagonist of nicotinic acetylcholine receptors. Biochemistry 2003; 42: 6353-62.
-
(2003)
Biochemistry
, vol.42
, pp. 6353-6362
-
-
Van Wagoner, R.M.1
Jacobsen, R.B.2
Olivera, B.M.3
Ireland, C.M.4
-
80
-
-
38349039512
-
Characterization of a novel Ψ-conotoxin from Conus parius Reeve
-
Lluisma AO, López-Vera E, Bulaj G, Watkins M, Olivera BM. Characterization of a novel Ψ-conotoxin from Conus parius Reeve. Toxicon 2008; 51: 174-80.
-
(2008)
Toxicon
, vol.51
, pp. 174-180
-
-
Lluisma, A.O.1
López-Vera, E.2
Bulaj, G.3
Watkins, M.4
Olivera, B.M.5
-
81
-
-
3042759058
-
αA-Conotoxin OIVA defines a new αA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors
-
Teichert RW, Rivier J, Dykert J, Cervini L, Gulyas J, Bulaj G, et al. αA-Conotoxin OIVA defines a new αA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors. Toxicon 2004; 44: 207-14.
-
(2004)
Toxicon
, vol.44
, pp. 207-214
-
-
Teichert, R.W.1
Rivier, J.2
Dykert, J.3
Cervini, L.4
Gulyas, J.5
Bulaj, G.6
-
82
-
-
31544458674
-
Definition and characterization of the short αAconotoxins: A single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor
-
Teichert RW, López-Vera E, Gulyas J, Watkins M, Rivier J, Olivera BM. Definition and characterization of the short αAconotoxins: A single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry 2006; 45: 1304-12.
-
(2006)
Biochemistry
, vol.45
, pp. 1304-1312
-
-
Teichert, R.W.1
López-Vera, E.2
Gulyas, J.3
Watkins, M.4
Rivier, J.5
Olivera, B.M.6
-
83
-
-
12744281120
-
A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor
-
Teichert RW, Rivier J, Torres J, Dykert J, Miller C, Olivera BM. A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor. J Neurosci 2005; 25: 732-6.
-
(2005)
J Neurosci
, vol.25
, pp. 732-736
-
-
Teichert, R.W.1
Rivier, J.2
Torres, J.3
Dykert, J.4
Miller, C.5
Olivera, B.M.6
-
84
-
-
0029080121
-
A new family of Conus peptides targeted to the nicotinic acetylcholine receptor
-
Hopkins C, Grilley M, Miller C, Shon KJ, Cruz LJ, Gray WR, et al. A new family of Conus peptides targeted to the nicotinic acetylcholine receptor. J Biol Chem, 1995, 270, 22361-7.
-
(1995)
J Biol Chem
, vol.270
, pp. 22361-22367
-
-
Hopkins, C.1
Grilley, M.2
Miller, C.3
Shon, K.J.4
Cruz, L.J.5
Gray, W.R.6
-
85
-
-
0031024894
-
NMR structure determination of a novel conotoxin, [Pro7,13] αA-conotoxin PIVA
-
Han KH, Hwang KJ, Kim SM, Kim SK, Gray WR, Olivera BM, et al. NMR structure determination of a novel conotoxin, [Pro7,13] αA-conotoxin PIVA. Biochemistry 1997; 36: 1669-77.
-
(1997)
Biochemistry
, vol.36
, pp. 1669-1677
-
-
Han, K.H.1
Hwang, K.J.2
Kim, S.M.3
Kim, S.K.4
Gray, W.R.5
Olivera, B.M.6
-
86
-
-
0030885085
-
Differential targeting of nicotinic acetylcholine receptors by novel αA-conotoxins
-
Jacobsen R, Yoshikami D, Ellison M, Martinez J, Gray WR, Cartier GE, et al. Differential targeting of nicotinic acetylcholine receptors by novel αA-conotoxins. J Biol Chem 1997; 272: 22531-7.
-
(1997)
J Biol Chem
, vol.272
, pp. 22531-22537
-
-
Jacobsen, R.1
Yoshikami, D.2
Ellison, M.3
Martinez, J.4
Gray, W.R.5
Cartier, G.E.6
-
87
-
-
0142149120
-
Solution conformation of αA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus
-
Chi SW, Park KH, Suk JE, Olivera BM, McIntosh JM, Han KH. Solution conformation of αA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus. J Biol Chem 2003; 278: 42208-13.
-
(2003)
J Biol Chem
, vol.278
, pp. 42208-42213
-
-
Chi, S.W.1
Park, K.H.2
Suk, J.E.3
Olivera, B.M.4
McIntosh, J.M.5
Han, K.H.6
-
88
-
-
34547637063
-
-
Jimenez EC, Olivera BM, Teichert RW. αC-conotoxin PrXA: A new family of nicotinic acetylcholine receptor antagonists. Biochemistry 2007; 46: 8717-24.
-
Jimenez EC, Olivera BM, Teichert RW. αC-conotoxin PrXA: A new family of nicotinic acetylcholine receptor antagonists. Biochemistry 2007; 46: 8717-24.
-
-
-
-
89
-
-
19644387101
-
-
Teichert RW, Jimenez EC, Olivera BM. αS-conotoxin RVIIIA: A structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors. Biochemistry 2005; 44: 7897-902.
-
Teichert RW, Jimenez EC, Olivera BM. αS-conotoxin RVIIIA: A structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors. Biochemistry 2005; 44: 7897-902.
-
-
-
-
90
-
-
45249105998
-
Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor
-
Teichert RW, Garcia CC, Potian JG, Schmidt JJ, Witzemann V, Olivera BM, et al. Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor. Ann N Y Acad Sci 2008; 1132: 61-70.
-
(2008)
Ann N Y Acad Sci
, vol.1132
, pp. 61-70
-
-
Teichert, R.W.1
Garcia, C.C.2
Potian, J.G.3
Schmidt, J.J.4
Witzemann, V.5
Olivera, B.M.6
-
91
-
-
33747666931
-
Identification of a novel class of nicotinic receptor antagonists: Dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum
-
Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, et al. Identification of a novel class of nicotinic receptor antagonists: Dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. J Biol Chem 2006; 281: 24745-55.
-
(2006)
J Biol Chem
, vol.281
, pp. 24745-24755
-
-
Loughnan, M.1
Nicke, A.2
Jones, A.3
Schroeder, C.I.4
Nevin, S.T.5
Adams, D.J.6
-
92
-
-
0024441605
-
κ-Neurotoxins: Heterodimer formation between different neuronal nicotinic receptor antagonists
-
Chiappinelli VA, Wolf KM. κ-Neurotoxins: Heterodimer formation between different neuronal nicotinic receptor antagonists. Biochemistry 1989; 28: 8543-7.
-
(1989)
Biochemistry
, vol.28
, pp. 8543-8547
-
-
Chiappinelli, V.A.1
Wolf, K.M.2
-
93
-
-
47249117482
-
Naturally occurring disul-fide-bound dimers of three-fingered toxins: A paradigm for biological activity diversification
-
Osipov AV, Kasheverov IE, Makarova YV, Starkov VG, Vorontsova OV, Ziganshin RK, et al. Naturally occurring disul-fide-bound dimers of three-fingered toxins: A paradigm for biological activity diversification. J Biol Chem 2008; 283: 14571-80.
-
(2008)
J Biol Chem
, vol.283
, pp. 14571-14580
-
-
Osipov, A.V.1
Kasheverov, I.E.2
Makarova, Y.V.3
Starkov, V.G.4
Vorontsova, O.V.5
Ziganshin, R.K.6
-
94
-
-
0026808424
-
Novel α- and ω-conotoxins from Conus striatus venom
-
Ramilo CA, Zafaralla GC, Nadasdi L, Hammerland LG, Yoshikami D, Gray WR, et al. Novel α- and ω-conotoxins from Conus striatus venom. Biochemistry 1992; 31: 9919-26.
-
(1992)
Biochemistry
, vol.31
, pp. 9919-9926
-
-
Ramilo, C.A.1
Zafaralla, G.C.2
Nadasdi, L.3
Hammerland, L.G.4
Yoshikami, D.5
Gray, W.R.6
-
95
-
-
33747080261
-
Discovery of a novel class of conotoxin from Conus litteratus, lt14a, with a unique cysteine pattern
-
Peng C, Tang S, Pi C, Liu J, Wang F, Wang L, et al. Discovery of a novel class of conotoxin from Conus litteratus, lt14a, with a unique cysteine pattern. Peptides 2006; 27: 2174-81.
-
(2006)
Peptides
, vol.27
, pp. 2174-2181
-
-
Peng, C.1
Tang, S.2
Pi, C.3
Liu, J.4
Wang, F.5
Wang, L.6
-
97
-
-
0032079381
-
Structure determination of the three disulfide bond isomers of α-conotoxin GI: A model for the role of disulfide bonds in structural stability
-
Gehrmann J, Alewood PF, Craik DJ. Structure determination of the three disulfide bond isomers of α-conotoxin GI: A model for the role of disulfide bonds in structural stability. J Mol Biol 1998; 278: 401-15
-
(1998)
J Mol Biol
, vol.278
, pp. 401-415
-
-
Gehrmann, J.1
Alewood, P.F.2
Craik, D.J.3
-
98
-
-
0022366836
-
Structure-activity relations of conotoxins at the neuromuscular junction
-
Hashimoto K, Uchida S, Yoshida H, Nishiuchi Y, Sakakibara S, Yukari K. Structure-activity relations of conotoxins at the neuromuscular junction. Eur J Pharmacol 1985; 118: 351-4.
-
(1985)
Eur J Pharmacol
, vol.118
, pp. 351-354
-
-
Hashimoto, K.1
Uchida, S.2
Yoshida, H.3
Nishiuchi, Y.4
Sakakibara, S.5
Yukari, K.6
-
99
-
-
34247859073
-
Structure of α-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics
-
Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, et al. Structure of α-conotoxin BuIA: Influences of disulfide connectivity on structural dynamics. BMC Struct Biol 2007; 7: 28.
-
(2007)
BMC Struct Biol
, vol.7
, pp. 28
-
-
Jin, A.H.1
Brandstaetter, H.2
Nevin, S.T.3
Tan, C.C.4
Clark, R.J.5
Adams, D.J.6
-
100
-
-
33947424873
-
Protein folding determinants: Structural features determining alternative disulfide pairing in α- and χ/λ-conotoxins
-
Kang TS, Radić Z, Talley TT, Jois SD, Taylor P, Kini RM. Protein folding determinants: Structural features determining alternative disulfide pairing in α- and χ/λ-conotoxins. Biochemistry 2007; 46: 3338-55.
-
(2007)
Biochemistry
, vol.46
, pp. 3338-3355
-
-
Kang, T.S.1
Radić, Z.2
Talley, T.T.3
Jois, S.D.4
Taylor, P.5
Kini, R.M.6
-
101
-
-
39649109254
-
The three-dimensional structure of the analgesic α-conotoxin, RgIA
-
Clark RJ, Daly NL, Halai R, Nevin ST, Adams DJ, Craik DJ. The three-dimensional structure of the analgesic α-conotoxin, RgIA. FEBS Lett 2008; 582: 597-602.
-
(2008)
FEBS Lett
, vol.582
, pp. 597-602
-
-
Clark, R.J.1
Daly, N.L.2
Halai, R.3
Nevin, S.T.4
Adams, D.J.5
Craik, D.J.6
-
102
-
-
0037073683
-
A new level of conotoxin diversity, a non-native disulfide bond connectivity in α-conotoxin AuIB reduces structural definition but increases biological activity
-
Dutton JL, Bansal PS, Hogg RC, Adams DJ, Alewood PF, Craik DJ. A new level of conotoxin diversity, a non-native disulfide bond connectivity in α-conotoxin AuIB reduces structural definition but increases biological activity. J Biol Chem 2002; 277: 48849-57.
-
(2002)
J Biol Chem
, vol.277
, pp. 48849-48857
-
-
Dutton, J.L.1
Bansal, P.S.2
Hogg, R.C.3
Adams, D.J.4
Alewood, P.F.5
Craik, D.J.6
-
104
-
-
0019414348
-
Peptide toxins from Conus geographus venom
-
Gray WR, Luque A, Olivera BM, Barrett J, Cruz LJ. Peptide toxins from Conus geographus venom. J Biol Chem 1981; 256: 4734-40.
-
(1981)
J Biol Chem
, vol.256
, pp. 4734-4740
-
-
Gray, W.R.1
Luque, A.2
Olivera, B.M.3
Barrett, J.4
Cruz, L.J.5
-
106
-
-
0032102261
-
Two distinct structures of α-conotoxin GI in aqueous solution
-
Maslennikov IV, Sobol AG, Gladky KV, Lugovskoy AA, Ostrovsky AG, Tsetlin VI, et al. Two distinct structures of α-conotoxin GI in aqueous solution. Eur J Biochem 1998; 254: 238-47.
-
(1998)
Eur J Biochem
, vol.254
, pp. 238-247
-
-
Maslennikov, I.V.1
Sobol, A.G.2
Gladky, K.V.3
Lugovskoy, A.A.4
Ostrovsky, A.G.5
Tsetlin, V.I.6
-
107
-
-
0029775108
-
Three-dimensional structure of the α-conotoxin GI at 1.2 Å resolution
-
Guddat LW, Martin JA, Shan L, Edmundson AB, Gray WR. Three-dimensional structure of the α-conotoxin GI at 1.2 Å resolution. Biochemistry 1996; 35: 11329-35.
-
(1996)
Biochemistry
, vol.35
, pp. 11329-11335
-
-
Guddat, L.W.1
Martin, J.A.2
Shan, L.3
Edmundson, A.B.4
Gray, W.R.5
-
108
-
-
0019390926
-
Peptides isolated from the venom of Conus geographus block neuromuscular transmission
-
McManus OB, Musick JR, Gonzalez C. Peptides isolated from the venom of Conus geographus block neuromuscular transmission. Neurosci Lett 1981; 25: 57-62.
-
(1981)
Neurosci Lett
, vol.25
, pp. 57-62
-
-
McManus, O.B.1
Musick, J.R.2
Gonzalez, C.3
-
109
-
-
0028170805
-
The α-conotoxins GI and MI distinguish between the nicotinic acetylcholine receptor agonist sites while SI does not
-
Hann RM, Pagán OR, Eterović VA. The α-conotoxins GI and MI distinguish between the nicotinic acetylcholine receptor agonist sites while SI does not. Biochemistry 1994; 33: 14058-63.
-
(1994)
Biochemistry
, vol.33
, pp. 14058-14063
-
-
Hann, R.M.1
Pagán, O.R.2
Eterović, V.A.3
-
110
-
-
0028984297
-
α-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors
-
Groebe DR, Dumm JM, Levitan ES, Abramson SN. α-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors. Mol Pharmacol 1995; 48: 105-11.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 105-111
-
-
Groebe, D.R.1
Dumm, J.M.2
Levitan, E.S.3
Abramson, S.N.4
-
111
-
-
33748756414
-
α-Conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors
-
Kasheverov IE, Zhmak MN, Vulfius CA, Gorbacheva EV, Mordvintsev DY, Utkin YN, et al. α-Conotoxin analogs with additional positive charge show increased selectivity towards Torpedo californica and some neuronal subtypes of nicotinic acetylcholine receptors. FEBS J 2006; 273: 4470-81.
-
(2006)
FEBS J
, vol.273
, pp. 4470-4481
-
-
Kasheverov, I.E.1
Zhmak, M.N.2
Vulfius, C.A.3
Gorbacheva, E.V.4
Mordvintsev, D.Y.5
Utkin, Y.N.6
-
112
-
-
0025472462
-
Neurotoxins distinguish between different neuronal nicotinic acetylcholine receptor subunit combinations
-
Luetje CW, Wada K, Rogers S, Abramson SN, Tsuji K, Heinemann S, et al. Neurotoxins distinguish between different neuronal nicotinic acetylcholine receptor subunit combinations. J Neurochem 1990; 55: 632-40.
-
(1990)
J Neurochem
, vol.55
, pp. 632-640
-
-
Luetje, C.W.1
Wada, K.2
Rogers, S.3
Abramson, S.N.4
Tsuji, K.5
Heinemann, S.6
-
113
-
-
0020364919
-
Isolation and structure of a peptide toxin from the marine snail Conus magus
-
McIntosh M, Cruz LJ, Hunkapiller MW, Gray WR Olivera BM. Isolation and structure of a peptide toxin from the marine snail Conus magus. Arch Biochem Biophys 1982; 218: 329-34.
-
(1982)
Arch Biochem Biophys
, vol.218
, pp. 329-334
-
-
McIntosh, M.1
Cruz, L.J.2
Hunkapiller, M.W.3
Gray, W.R.4
Olivera, B.M.5
-
114
-
-
0021069422
-
Disulfide bonding and conformational states
-
Gray WR, Rivier JE, Galyean R, Cruz LJ, Olivera BM. Conotoxin MI. Disulfide bonding and conformational states. J Biol Chem 1983; 258: 12247-51.
-
(1983)
J Biol Chem
, vol.258
, pp. 12247-12251
-
-
Gray, W.R.1
Rivier, J.E.2
Galyean, R.3
Cruz, L.J.4
Olivera, B.M.5
Conotoxin, M.I.6
-
116
-
-
0032857339
-
Critical residues influence the affinity and selectivity of α-conotoxin MI for nicotinic acetylcholine receptors
-
Jacobsen RB, DelaCruz RG, Grose JH, McIntosh JM, Yoshikami D, Olivera BM. Critical residues influence the affinity and selectivity of α-conotoxin MI for nicotinic acetylcholine receptors. Biochemistry 1999; 38: 13310-5.
-
(1999)
Biochemistry
, vol.38
, pp. 13310-13315
-
-
Jacobsen, R.B.1
DelaCruz, R.G.2
Grose, J.H.3
McIntosh, J.M.4
Yoshikami, D.5
Olivera, B.M.6
-
117
-
-
2542581752
-
Iodo-α-conotoxin MI selectively binds the α/δ subunit interface of muscle nicotinic acetylcholine receptors
-
Luo S, McIntosh JM. Iodo-α-conotoxin MI selectively binds the α/δ subunit interface of muscle nicotinic acetylcholine receptors. Biochemistry 2004; 43: 6656-62.
-
(2004)
Biochemistry
, vol.43
, pp. 6656-6662
-
-
Luo, S.1
McIntosh, J.M.2
-
118
-
-
0023782870
-
Phylogenetic specificity of cholinergic ligands: α-conotoxin SI
-
Zafaralla GC, Ramilo C, Gray WR, Karlstrom R, Olivera BM, Cruz LJ. Phylogenetic specificity of cholinergic ligands: α-conotoxin SI. Biochemistry 1988; 27: 7102-5.
-
(1988)
Biochemistry
, vol.27
, pp. 7102-7105
-
-
Zafaralla, G.C.1
Ramilo, C.2
Gray, W.R.3
Karlstrom, R.4
Olivera, B.M.5
Cruz, L.J.6
-
119
-
-
0034617477
-
Solution structure of α-conotoxin SI
-
Benie AJ, Whitford D, Hargittai B, Barany G, Janes RW. Solution structure of α-conotoxin SI. FEBS Lett 2000; 476: 287-95.
-
(2000)
FEBS Lett
, vol.476
, pp. 287-295
-
-
Benie, A.J.1
Whitford, D.2
Hargittai, B.3
Barany, G.4
Janes, R.W.5
-
120
-
-
0030982176
-
Determinants involved in the affinity of α-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors
-
Groebe DR, Gray WR, Abramson SN. Determinants involved in the affinity of α-conotoxins GI and SI for the muscle subtype of nicotinic acetylcholine receptors. Biochemistry 1997; 36: 6469-74.
-
(1997)
Biochemistry
, vol.36
, pp. 6469-6474
-
-
Groebe, D.R.1
Gray, W.R.2
Abramson, S.N.3
-
121
-
-
0030791182
-
The 9-arginine residue of α-conotoxin GI is responsible for its selective high affinity for the αγ agonist site on the electric organ acetylcholine receptor
-
Hann RM, Pagan OR, Gregory LM, Jacome T, Eterovic VA. The 9-arginine residue of α-conotoxin GI is responsible for its selective high affinity for the αγ agonist site on the electric organ acetylcholine receptor. Biochemistry 1997; 36: 9051-6.
-
(1997)
Biochemistry
, vol.36
, pp. 9051-9056
-
-
Hann, R.M.1
Pagan, O.R.2
Gregory, L.M.3
Jacome, T.4
Eterovic, V.A.5
-
122
-
-
0025996975
-
α-Conotoxins, small peptide probes of nicotinic acetylcholine receptors
-
Myers RA, Zafaralla GC, Gray WR, Abbott J, Cruz LJ, Olivera BM. α-Conotoxins, small peptide probes of nicotinic acetylcholine receptors. Biochemistry 1991; 30: 9370-7.
-
(1991)
Biochemistry
, vol.30
, pp. 9370-9377
-
-
Myers, R.A.1
Zafaralla, G.C.2
Gray, W.R.3
Abbott, J.4
Cruz, L.J.5
Olivera, B.M.6
-
123
-
-
0033545910
-
Biochemical characterization and nuclear magnetic resonance structure of novel α-conotoxins isolated from the venom of Conus consors
-
Favreau P, Krimm I, Le Gall F, Bobenrieth MJ, Lamthanh H, Bouet F, et al. Biochemical characterization and nuclear magnetic resonance structure of novel α-conotoxins isolated from the venom of Conus consors. Biochemistry 1999; 38: 6317-26.
-
(1999)
Biochemistry
, vol.38
, pp. 6317-6326
-
-
Favreau, P.1
Krimm, I.2
Le Gall, F.3
Bobenrieth, M.J.4
Lamthanh, H.5
Bouet, F.6
-
124
-
-
34250835817
-
Two potent α3/5 conotoxins from piscivorous Conus achatinus
-
Liu L, Chew G, Hawrot E, Chi C, Wang C. Two potent α3/5 conotoxins from piscivorous Conus achatinus. Acta Biochim Biophys Sin (Shanghai) 2007; 39: 438-44.
-
(2007)
Acta Biochim Biophys Sin (Shanghai)
, vol.39
, pp. 438-444
-
-
Liu, L.1
Chew, G.2
Hawrot, E.3
Chi, C.4
Wang, C.5
-
125
-
-
0028361574
-
A nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImI
-
McIntosh JM, Yoshikami D, Mahe E, Nielsen DB, Rivier JE, Gray WR, et al. A nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImI. J Biol Chem 1994; 269: 16733-9.
-
(1994)
J Biol Chem
, vol.269
, pp. 16733-16739
-
-
McIntosh, J.M.1
Yoshikami, D.2
Mahe, E.3
Nielsen, D.B.4
Rivier, J.E.5
Gray, W.R.6
-
126
-
-
0033067115
-
NMR spatial structure of α-conotoxin ImI reveals a common scaffold in snail and snake toxins recognizing neuronal nicotinic acetylcholine receptors
-
Maslennikov IV, Shenkarev ZO, Zhmak MN, Ivanov VT, Methfessel C, Tsetlin VI, et al. NMR spatial structure of α-conotoxin ImI reveals a common scaffold in snail and snake toxins recognizing neuronal nicotinic acetylcholine receptors. FEBS Lett 1999; 444: 275-80.
-
(1999)
FEBS Lett
, vol.444
, pp. 275-280
-
-
Maslennikov, I.V.1
Shenkarev, Z.O.2
Zhmak, M.N.3
Ivanov, V.T.4
Methfessel, C.5
Tsetlin, V.I.6
-
127
-
-
0032921719
-
Solution structure of α-conotoxin ImI determined by two-dimensional NMR spectroscopy
-
Gouda H, Hirono S. Solution structure of α-conotoxin ImI determined by two-dimensional NMR spectroscopy. Biochim Biophys Acta 1999; 1431: 384-94.
-
(1999)
Biochim Biophys Acta
, vol.1431
, pp. 384-394
-
-
Gouda, H.1
Hirono, S.2
-
129
-
-
0040017648
-
NMR solution structure of α-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors
-
Rogers JP, Luginbuhl P, Shen GS, McCabe RT, Stevens RC, Wemmer DE. NMR solution structure of α-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry 1999; 38: 3874-82.
-
(1999)
Biochemistry
, vol.38
, pp. 3874-3882
-
-
Rogers, J.P.1
Luginbuhl, P.2
Shen, G.S.3
McCabe, R.T.4
Stevens, R.C.5
Wemmer, D.E.6
-
130
-
-
0028981913
-
α-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: Preferential inhibition of homomeric α7 and α9 receptors
-
Johnson DS, Martinez J, Elgoyhen AB, Heinemann SF, McIntosh JM. α-Conotoxin ImI exhibits subtype-specific nicotinic acetylcholine receptor blockade: Preferential inhibition of homomeric α7 and α9 receptors. Mol Pharmacol 1995; 48: 194-9.
-
(1995)
Mol Pharmacol
, vol.48
, pp. 194-199
-
-
Johnson, D.S.1
Martinez, J.2
Elgoyhen, A.B.3
Heinemann, S.F.4
McIntosh, J.M.5
-
131
-
-
0030431228
-
A competitive antagonist at α-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons
-
Pereira EF, Alkondon M, McIntosh JM, Albuquerque E. X. α-Conotoxin-ImI: A competitive antagonist at α-bungarotoxin-sensitive neuronal nicotinic receptors in hippocampal neurons. J Pharmacol Exp Ther 1996; 278: 1472-83.
-
(1996)
J Pharmacol Exp Ther
, vol.278
, pp. 1472-1483
-
-
Pereira, E.F.1
Alkondon, M.2
McIntosh, J.M.3
Albuquerque, E.4
α-Conotoxin-ImI, X.5
-
132
-
-
0037428436
-
α-Conotoxins ImI and ImII. Similar α7 nicotinic receptor antagonists act at different sites
-
Ellison M, McIntosh JM, Olivera BM. α-Conotoxins ImI and ImII. Similar α7 nicotinic receptor antagonists act at different sites. J Biol Chem 2003; 278: 757-64.
-
(2003)
J Biol Chem
, vol.278
, pp. 757-764
-
-
Ellison, M.1
McIntosh, J.M.2
Olivera, B.M.3
-
133
-
-
32244443936
-
α-RgIA: A novel conotoxin that specifically and potently blocks the α9α10 nAChR
-
Ellison M, Haberlandt C, Gomez-Casati ME, Watkins M, Elgoyhen AB, McIntosh JM, et al. α-RgIA: A novel conotoxin that specifically and potently blocks the α9α10 nAChR. Biochemistry 2006; 45: 1511-7.
-
(2006)
Biochemistry
, vol.45
, pp. 1511-1517
-
-
Ellison, M.1
Haberlandt, C.2
Gomez-Casati, M.E.3
Watkins, M.4
Elgoyhen, A.B.5
McIntosh, J.M.6
-
134
-
-
11144331404
-
α-Conotoxins ImI and ImII target distinct regions of the human α7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes
-
Ellison M, Gao F, Wang HL, Sine SM, McIntosh JM, Olivera BM. α-Conotoxins ImI and ImII target distinct regions of the human α7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes. Biochemistry 2004; 43: 16019-26.
-
(2004)
Biochemistry
, vol.43
, pp. 16019-16026
-
-
Ellison, M.1
Gao, F.2
Wang, H.L.3
Sine, S.M.4
McIntosh, J.M.5
Olivera, B.M.6
-
135
-
-
0032994494
-
α-Conotoxin ImI inhibits the α-bungarotoxin-resistant nicotinic response in bovine adrenal chromaffin cells
-
Broxton NM, Down JG, Gehrmann J, Alewood PF, Satchell DG, Livett BG. α-Conotoxin ImI inhibits the α-bungarotoxin-resistant nicotinic response in bovine adrenal chromaffin cells. J Neurochem 1999; 72: 1656-62.
-
(1999)
J Neurochem
, vol.72
, pp. 1656-1662
-
-
Broxton, N.M.1
Down, J.G.2
Gehrmann, J.3
Alewood, P.F.4
Satchell, D.G.5
Livett, B.G.6
-
136
-
-
33845212316
-
Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors
-
Vincler M, Wittenauer S, Parker R, Ellison M, Olivera BM, McIntosh JM. Molecular mechanism for analgesia involving specific antagonism of α9α10 nicotinic acetylcholine receptors. Proc Natl Acad Sci USA 2006; 103: 17880-4.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17880-17884
-
-
Vincler, M.1
Wittenauer, S.2
Parker, R.3
Ellison, M.4
Olivera, B.M.5
McIntosh, J.M.6
-
137
-
-
40849129937
-
α-RgIA, a novel conotoxin that blocks the α9α10 nAChR: Structure and identification of key receptor-binding residues
-
Ellison M, Feng ZP, Park AJ, Zhang X, Olivera BM, McIntosh JM, et al. α-RgIA, a novel conotoxin that blocks the α9α10 nAChR: Structure and identification of key receptor-binding residues. J Mol Biol 2008; 377: 1216-27.
-
(2008)
J Mol Biol
, vol.377
, pp. 1216-1227
-
-
Ellison, M.1
Feng, Z.P.2
Park, A.J.3
Zhang, X.4
Olivera, B.M.5
McIntosh, J.M.6
-
138
-
-
12844251304
-
α-Conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors
-
Azam L, Dowell C, Watkins M, Stitzel JA, Olivera BM, McIntosh JM. α-Conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors. J Biol Chem 2005; 280: 80-7.
-
(2005)
J Biol Chem
, vol.280
, pp. 80-87
-
-
Azam, L.1
Dowell, C.2
Watkins, M.3
Stitzel, J.A.4
Olivera, B.M.5
McIntosh, J.M.6
-
139
-
-
33748796351
-
NMR structure determination of α-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold
-
Chi SW, Kim DH, Olivera BM, McIntosh JM, Han KH. NMR structure determination of α-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold. Biochem Biophys Res Commun 2006; 349: 1228-34.
-
Biochem Biophys Res Commun 2006; 349: 1228-34
-
-
Chi, S.W.1
Kim, D.H.2
Olivera, B.M.3
McIntosh, J.M.4
Han, K.H.5
-
140
-
-
34249072034
-
A novel alpha conotoxin (α-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors
-
López-Vera E, Jacobsen RB, Ellison M, Olivera BM, Teichert RW. A novel alpha conotoxin (α-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors. Toxicon 2007; 49: 1193-9.
-
(2007)
Toxicon
, vol.49
, pp. 1193-1199
-
-
López-Vera, E.1
Jacobsen, R.B.2
Ellison, M.3
Olivera, B.M.4
Teichert, R.W.5
-
141
-
-
0032213318
-
α-Conotoxin AuIB selectively blocks α3β4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release
-
Luo S, Kulak JM, Cartier GE, Jacobsen RB, Yoshikami D, Olivera BM, et al. α-Conotoxin AuIB selectively blocks α3β4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release. J Neurosci 1998; 18: 8571-9.
-
(1998)
J Neurosci
, vol.18
, pp. 8571-8579
-
-
Luo, S.1
Kulak, J.M.2
Cartier, G.E.3
Jacobsen, R.B.4
Yoshikami, D.5
Olivera, B.M.6
-
143
-
-
0142153384
-
α-Conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors
-
Nicke A, Samochocki M, Loughnan ML, Bansal PS, Maelicke A, Lewis RJ. α-Conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors. FEBS Lett 2003; 554: 219-23.
-
(2003)
FEBS Lett
, vol.554
, pp. 219-223
-
-
Nicke, A.1
Samochocki, M.2
Loughnan, M.L.3
Bansal, P.S.4
Maelicke, A.5
Lewis, R.J.6
-
144
-
-
0028168296
-
New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors
-
Fainzilber M, Hasson A, Oren R, Burlingame AL, Gordon D, Spira ME, et al. New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 1994; 33: 9523-9.
-
(1994)
Biochemistry
, vol.33
, pp. 9523-9529
-
-
Fainzilber, M.1
Hasson, A.2
Oren, R.3
Burlingame, A.L.4
Gordon, D.5
Spira, M.E.6
-
145
-
-
0032964781
-
Identification of tyrosine sulfation in Conus pennaceus conotoxins α-PnIA and α-PnIB: Further investigation of labile sulfo- and phosphopeptides by electrospray, matrix-assisted laser desorption/ionization (MALDI) and atmospheric pressure MALDI mass spectrometry
-
Wolfender JL, Chu F, Ball H, Wolfender F, Fainzilber M, Baldwin MA, et al. Identification of tyrosine sulfation in Conus pennaceus conotoxins α-PnIA and α-PnIB: Further investigation of labile sulfo- and phosphopeptides by electrospray, matrix-assisted laser desorption/ionization (MALDI) and atmospheric pressure MALDI mass spectrometry. J Mass Spectrom 1999; 34: 447-54.
-
(1999)
J Mass Spectrom
, vol.34
, pp. 447-454
-
-
Wolfender, J.L.1
Chu, F.2
Ball, H.3
Wolfender, F.4
Fainzilber, M.5
Baldwin, M.A.6
-
146
-
-
0033579496
-
Single amino acid substitutions in α-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor
-
Hogg RC, Miranda LP, Craik DJ, Lewis RJ, Alewood PF, Adams DJ. Single amino acid substitutions in α-conotoxin PnIA shift selectivity for subtypes of the mammalian neuronal nicotinic acetylcholine receptor. J Biol Chem 1999; 274: 36559-64.
-
(1999)
J Biol Chem
, vol.274
, pp. 36559-36564
-
-
Hogg, R.C.1
Miranda, L.P.2
Craik, D.J.3
Lewis, R.J.4
Alewood, P.F.5
Adams, D.J.6
-
147
-
-
0030584684
-
The 1.1 Å crystal structure of the neuronal acetylcholine receptor antagonist, α-conotoxin PnIA from Conus pennaceus
-
Hu SH, Gehrmann J, Guddat LW, Alewood PF, Craik DJ, Martin JL. The 1.1 Å crystal structure of the neuronal acetylcholine receptor antagonist, α-conotoxin PnIA from Conus pennaceus. Structure 1996; 4: 417-23.
-
(1996)
Structure
, vol.4
, pp. 417-423
-
-
Hu, S.H.1
Gehrmann, J.2
Guddat, L.W.3
Alewood, P.F.4
Craik, D.J.5
Martin, J.L.6
-
148
-
-
0033517843
-
Single-residue alteration in α-conotoxin PnIA switches its nAChR subtype selectivity
-
Luo S, Nguyen TA, Cartier GE, Olivera BM, Yoshikami D, McIntosh JM. Single-residue alteration in α-conotoxin PnIA switches its nAChR subtype selectivity. Biochemistry 1999; 38: 14542-8.
-
(1999)
Biochemistry
, vol.38
, pp. 14542-14548
-
-
Luo, S.1
Nguyen, T.A.2
Cartier, G.E.3
Olivera, B.M.4
Yoshikami, D.5
McIntosh, J.M.6
-
149
-
-
0037622708
-
Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors
-
Everhart D, Reiller E, Mirzoian A, McIntosh JM, Malhotra A, Luetje CW. Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors. J Pharmacol Exp Ther 2003; 306: 664-70.
-
(2003)
J Pharmacol Exp Ther
, vol.306
, pp. 664-670
-
-
Everhart, D.1
Reiller, E.2
Mirzoian, A.3
McIntosh, J.M.4
Malhotra, A.5
Luetje, C.W.6
-
150
-
-
24044466131
-
β2 Subunit contribution to 4/7 α-conotoxin binding to the nicotinic acetylcholine receptor
-
Dutertre S, Nicke A, Lewis RJ. β2 Subunit contribution to 4/7 α-conotoxin binding to the nicotinic acetylcholine receptor. J Biol Chem 2005; 280: 30460-8.
-
(2005)
J Biol Chem
, vol.280
, pp. 30460-30468
-
-
Dutertre, S.1
Nicke, A.2
Lewis, R.J.3
-
151
-
-
0030968583
-
Crystal structure at 1.1 Å resolution of α-conotoxin PnIB: Comparison with α-conotoxins PnIA and GI
-
Hu SH, Gehrmann J, Alewood PF, Craik DJ, Martin JL. Crystal structure at 1.1 Å resolution of α-conotoxin PnIB: Comparison with α-conotoxins PnIA and GI. Biochemistry 1997; 36: 11323-30.
-
(1997)
Biochemistry
, vol.36
, pp. 11323-11330
-
-
Hu, S.H.1
Gehrmann, J.2
Alewood, P.F.3
Craik, D.J.4
Martin, J.L.5
-
153
-
-
0032547066
-
α-Conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors
-
Loughnan M, Bond T, Atkins A, Cuevas J, Adams DJ, Broxton NM, et al. α-Conotoxin EpI, a novel sulfated peptide from Conus episcopatus that selectively targets neuronal nicotinic acetylcholine receptors. J Biol Chem 1998; 273: 15667-74.
-
(1998)
J Biol Chem
, vol.273
, pp. 15667-15674
-
-
Loughnan, M.1
Bond, T.2
Atkins, A.3
Cuevas, J.4
Adams, D.J.5
Broxton, N.M.6
-
154
-
-
0032543962
-
15]EpI, a novel α-conotoxin from Conus episcopatus, solved by direct methods
-
15]EpI, a novel α-conotoxin from Conus episcopatus, solved by direct methods. Biochemistry 1998; 37: 11425-33.
-
(1998)
Biochemistry
, vol.37
, pp. 11425-11433
-
-
Hu, S.H.1
Loughnan, M.2
Miller, R.3
Weeks, C.M.4
Blessing, R.H.5
Alewood, P.F.6
-
155
-
-
1242273820
-
Chemical and functional identification and characterization of novel sulfated α-conotoxins from the cone snail Conus anemone
-
Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated α-conotoxins from the cone snail Conus anemone. J Med Chem 2004; 47: 1234-41.
-
(2004)
J Med Chem
, vol.47
, pp. 1234-1241
-
-
Loughnan, M.L.1
Nicke, A.2
Jones, A.3
Adams, D.J.4
Alewood, P.F.5
Lewis, R.J.6
-
156
-
-
0038661000
-
A novel α-conotoxin identified by gene sequencing is active in suppressing the vascular response to selective stimulation of sensory nerves in vivo
-
Sandall DW, Satkunanathan N, Keays DA, Polidano MA, Liping X, Pham V, et al. A novel α-conotoxin identified by gene sequencing is active in suppressing the vascular response to selective stimulation of sensory nerves in vivo. Biochemistry 2003; 42: 6904-11.
-
(2003)
Biochemistry
, vol.42
, pp. 6904-6911
-
-
Sandall, D.W.1
Satkunanathan, N.2
Keays, D.A.3
Polidano, M.A.4
Liping, X.5
Pham, V.6
-
157
-
-
33747372837
-
The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1
-
Clark RJ, Fischer H, Nevin ST, Adams DJ, Craik DJ. The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1. J Biol Chem 2006; 281: 23254-63.
-
(2006)
J Biol Chem
, vol.281
, pp. 23254-23263
-
-
Clark, R.J.1
Fischer, H.2
Nevin, S.T.3
Adams, D.J.4
Craik, D.J.5
-
158
-
-
0029871748
-
A new α-conotoxin which targets α3β2 nicotinic acetylcholine receptors
-
Cartier GE, Yoshikami D, Gray WR, Luo S, Olivera BM, McIntosh JM. A new α-conotoxin which targets α3β2 nicotinic acetylcholine receptors. J Biol Chem 1996; 271: 7522-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 7522-7528
-
-
Cartier, G.E.1
Yoshikami, D.2
Gray, W.R.3
Luo, S.4
Olivera, B.M.5
McIntosh, J.M.6
-
160
-
-
0032506167
-
Three-dimensional solution structure of α-conotoxin MII by NMR spectroscopy: Effects of solution environment on helicity
-
Hill JM, Oomen CJ, Miranda LP, Bingham JP, Alewood PF, Craik DJ. Three-dimensional solution structure of α-conotoxin MII by NMR spectroscopy: Effects of solution environment on helicity. Biochemistry 1998; 37: 15621-30.
-
(1998)
Biochemistry
, vol.37
, pp. 15621-15630
-
-
Hill, J.M.1
Oomen, C.J.2
Miranda, L.P.3
Bingham, J.P.4
Alewood, P.F.5
Craik, D.J.6
-
161
-
-
0031026798
-
Determinants of specificity for α-conotoxin MII on α3β2 neuronal nicotinic receptors
-
Harvey SC, McIntosh JM, Cartier GE, Maddox FN, Luetje CW. Determinants of specificity for α-conotoxin MII on α3β2 neuronal nicotinic receptors. Mol Pharmacol 1997; 51: 336-42.
-
(1997)
Mol Pharmacol
, vol.51
, pp. 336-342
-
-
Harvey, S.C.1
McIntosh, J.M.2
Cartier, G.E.3
Maddox, F.N.4
Luetje, C.W.5
-
163
-
-
0034732244
-
Conus peptides: Novel probes for nicotinic acetylcholine receptor structure and function
-
McIntosh JM, Gardner S, Luo S, Garrett JE, Yoshikami D. Conus peptides: Novel probes for nicotinic acetylcholine receptor structure and function. Eur. J. Pharmacol 2000; 393: 205-8.
-
(2000)
Eur. J. Pharmacol
, vol.393
, pp. 205-208
-
-
McIntosh, J.M.1
Gardner, S.2
Luo, S.3
Garrett, J.E.4
Yoshikami, D.5
-
164
-
-
0032586861
-
Functional α6-containing nicotinic receptors are present in chick retina
-
Vailati S, Hanke W, Bejan A, Barabino B, Longhi R, Balestra B, et al. Functional α6-containing nicotinic receptors are present in chick retina. Mol Pharmacol 1999; 56: 11-9.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 11-19
-
-
Vailati, S.1
Hanke, W.2
Bejan, A.3
Barabino, B.4
Longhi, R.5
Balestra, B.6
-
165
-
-
0042360501
-
Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice
-
Champtiaux N, Gotti C, Cordero-Erausquin M, David DJ, Przybylski C, Léna C, et al. Subunit composition of functional nicotinic receptors in dopaminergic neurons investigated with knock-out mice. J Neurosci 2003; 23: 7820-9.
-
(2003)
J Neurosci
, vol.23
, pp. 7820-7829
-
-
Champtiaux, N.1
Gotti, C.2
Cordero-Erausquin, M.3
David, D.J.4
Przybylski, C.5
Léna, C.6
-
166
-
-
1842428563
-
Analogs of α-conotoxin MII are selective for α6-containing nicotinic acetylcholine receptors
-
McIntosh JM, Azam L, Staheli S, Dowell C, Lindstrom JM, Kuryatov A, et al. Analogs of α-conotoxin MII are selective for α6-containing nicotinic acetylcholine receptors. Mol Pharmacol 2004; 65: 944-52.
-
(2004)
Mol Pharmacol
, vol.65
, pp. 944-952
-
-
McIntosh, J.M.1
Azam, L.2
Staheli, S.3
Dowell, C.4
Lindstrom, J.M.5
Kuryatov, A.6
-
167
-
-
19944433294
-
Heterologous expression of human α6β4β3α5 nicotinic acetylcholine receptors: Binding properties consistent with their natural expression require quaternary subunit assembly including the α5 subunit
-
Grinevich VP, Letchworth SR, Lindenberger KA, Menager J, Mary V, Sadieva KA, et al. Heterologous expression of human α6β4β3α5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the α5 subunit. J Pharmacol Exp Ther 2005; 312: 619-26.
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 619-626
-
-
Grinevich, V.P.1
Letchworth, S.R.2
Lindenberger, K.A.3
Menager, J.4
Mary, V.5
Sadieva, K.A.6
-
168
-
-
25144467556
-
Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: Identification of a new native nAChR subtype α3β2(α5 or β3) enriched in retinocollicular afferents
-
Gotti C, Moretti M, Zanardi A, Gaimarri A, Champtiaux N, Changeux JP, et al. Heterogeneity and selective targeting of neuronal nicotinic acetylcholine receptor (nAChR) subtypes expressed on retinal afferents of the superior colliculus and lateral geniculate nucleus: identification of a new native nAChR subtype α3β2(α5 or β3) enriched in retinocollicular afferents. Mol Pharmacol 2005; 68: 1162-71.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1162-1171
-
-
Gotti, C.1
Moretti, M.2
Zanardi, A.3
Gaimarri, A.4
Champtiaux, N.5
Changeux, J.P.6
-
169
-
-
0348010302
-
The β3 nicotinic receptor subunit: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors
-
Cui C, Booker TK, Allen RS, Grady SR, Whiteaker P, Marks MJ, et al. The β3 nicotinic receptor subunit: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors. J Neurosci 2003; 23: 11045-53.
-
(2003)
J Neurosci
, vol.23
, pp. 11045-11053
-
-
Cui, C.1
Booker, T.K.2
Allen, R.S.3
Grady, S.R.4
Whiteaker, P.5
Marks, M.J.6
-
170
-
-
0037072765
-
α-Conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors
-
McIntosh JM, Dowell C, Watkins M, Garrett JE, Yoshikami D, Olivera BM. α-Conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors. J Biol Chem 2002; 277: 33610-5.
-
(2002)
J Biol Chem
, vol.277
, pp. 33610-33615
-
-
McIntosh, J.M.1
Dowell, C.2
Watkins, M.3
Garrett, J.E.4
Yoshikami, D.5
Olivera, B.M.6
-
171
-
-
2942722362
-
Solution conformation of α-conotoxin GIC, a novel potent antagonist of α3β2 nicotinic acetylcholine receptors
-
Chi SW, Kim DH, Olivera BM, McIntosh JM, Han KH. Solution conformation of α-conotoxin GIC, a novel potent antagonist of α3β2 nicotinic acetylcholine receptors. Biochem J 2004; 380: 347-52.
-
(2004)
Biochem J
, vol.380
, pp. 347-352
-
-
Chi, S.W.1
Kim, D.H.2
Olivera, B.M.3
McIntosh, J.M.4
Han, K.H.5
-
172
-
-
0037474213
-
Isolation, structure, and activity of GID, a novel α4/ 7-conotoxin with an extended N-terminal sequence
-
Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, et al. Isolation, structure, and activity of GID, a novel α4/ 7-conotoxin with an extended N-terminal sequence. J Biol Chem 2003; 278: 3137-44.
-
(2003)
J Biol Chem
, vol.278
, pp. 3137-3144
-
-
Nicke, A.1
Loughnan, M.L.2
Millard, E.L.3
Alewood, P.F.4
Adams, D.J.5
Daly, N.L.6
-
173
-
-
0141681001
-
α-Conotoxin PIA is selective for α6 subunit-containing nicotinic acetylcholine receptors
-
Dowell C, Olivera BM, Garrett JE, Staheli ST, Watkins M, Kuryatov A, et al. α-Conotoxin PIA is selective for α6 subunit-containing nicotinic acetylcholine receptors. J Neurosci 2003; 23: 8445-52.
-
(2003)
J Neurosci
, vol.23
, pp. 8445-8452
-
-
Dowell, C.1
Olivera, B.M.2
Garrett, J.E.3
Staheli, S.T.4
Watkins, M.5
Kuryatov, A.6
-
174
-
-
27844595802
-
Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors
-
Chi SW, Lee SH, Kim DH, Kim JS, Olivera BM, McIntosh JM, et al. Solution structure of α-conotoxin PIA, a novel antagonist of α6 subunit containing nicotinic acetylcholine receptors. Biochem Biophys Res Commun 2005; 338: 1990-7.
-
(2005)
Biochem Biophys Res Commun
, vol.338
, pp. 1990-1997
-
-
Chi, S.W.1
Lee, S.H.2
Kim, D.H.3
Kim, J.S.4
Olivera, B.M.5
McIntosh, J.M.6
-
175
-
-
34249904657
-
Discovery, synthesis, and structure activity of a highly selective α7 nicotinic acetylcholine receptor antagonist
-
Whiteaker P, Christensen S, Yoshikami D, Dowell C, Watkins M, Gulyas J, et al. Discovery, synthesis, and structure activity of a highly selective α7 nicotinic acetylcholine receptor antagonist. Biochemistry 2007; 46: 6628-38.
-
(2007)
Biochemistry
, vol.46
, pp. 6628-6638
-
-
Whiteaker, P.1
Christensen, S.2
Yoshikami, D.3
Dowell, C.4
Watkins, M.5
Gulyas, J.6
-
176
-
-
0028973580
-
α-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity
-
Martinez JS, Olivera BM, Gray WR, Craig AG, Groebe DR, Abramson SN, et al. α-Conotoxin EI, a new nicotinic acetylcholine receptor antagonist with novel selectivity. Biochemistry 1995; 34: 14519-26.
-
(1995)
Biochemistry
, vol.34
, pp. 14519-14526
-
-
Martinez, J.S.1
Olivera, B.M.2
Gray, W.R.3
Craig, A.G.4
Groebe, D.R.5
Abramson, S.N.6
-
177
-
-
0035966112
-
Solution conformation of α-conotoxin EI, a neuromuscular toxin specific for the α1/δ subunit interface of Torpedo nicotinic acetylcholine receptor
-
Park KH, Suk JE, Jacobsen R, Gray WR, McIntosh JM, Han KH. Solution conformation of α-conotoxin EI, a neuromuscular toxin specific for the α1/δ subunit interface of Torpedo nicotinic acetylcholine receptor. J Biol Chem 2001; 276: 49028-33.
-
(2001)
J Biol Chem
, vol.276
, pp. 49028-49033
-
-
Park, K.H.1
Suk, J.E.2
Jacobsen, R.3
Gray, W.R.4
McIntosh, J.M.5
Han, K.H.6
-
178
-
-
34447636449
-
Novel α-conotoxins from Conus spurius and the α-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors
-
López-Vera E, Aguilar MB, Schiavon E, Marinzi C, Ortiz E, Restano Cassulini R, et al. Novel α-conotoxins from Conus spurius and the α-conotoxin EI share high-affinity potentiation and low-affinity inhibition of nicotinic acetylcholine receptors. FEBS J 2007; 274: 3972-85.
-
(2007)
FEBS J
, vol.274
, pp. 3972-3985
-
-
López-Vera, E.1
Aguilar, M.B.2
Schiavon, E.3
Marinzi, C.4
Ortiz, E.5
Restano Cassulini, R.6
-
179
-
-
24044496218
-
A novel α-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat α9α10 and α7 nicotinic cholinergic receptors
-
McIntosh JM, Plazas PV, Watkins M, Gomez-Casati ME, Olivera BM, Elgoyhen AB. A novel α-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat α9α10 and α7 nicotinic cholinergic receptors. J Biol Chem 2005; 280: 30107-12.
-
(2005)
J Biol Chem
, vol.280
, pp. 30107-30112
-
-
McIntosh, J.M.1
Plazas, P.V.2
Watkins, M.3
Gomez-Casati, M.E.4
Olivera, B.M.5
Elgoyhen, A.B.6
-
180
-
-
33747652956
-
α-Conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as α3β2 and α7 nicotinic acetylcholine receptors
-
Talley TT, Olivera BM, Han KH, Christensen SB, Dowell C, Tsigelny I, et al. α-Conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as α3β2 and α7 nicotinic acetylcholine receptors. J Biol Chem 2006; 281: 24678-86.
-
(2006)
J Biol Chem
, vol.281
, pp. 24678-24686
-
-
Talley, T.T.1
Olivera, B.M.2
Han, K.H.3
Christensen, S.B.4
Dowell, C.5
Tsigelny, I.6
-
181
-
-
33646431474
-
Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes
-
Chi SW, Kim DH, Olivera BM, McIntosh JM, Han KH. Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes. Biochem Biophys Res Commun 2006; 345: 248-54.
-
(2006)
Biochem Biophys Res Commun
, vol.345
, pp. 248-254
-
-
Chi, S.W.1
Kim, D.H.2
Olivera, B.M.3
McIntosh, J.M.4
Han, K.H.5
-
182
-
-
34548056414
-
AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity
-
Dutertre S, Ulens C, Büttner R, Fish A, van Elk R, Kendel Y, et al. AChBP-targeted α-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. EMBO J 2007; 26: 3858-67
-
(2007)
EMBO J
, vol.26
, pp. 3858-3867
-
-
Dutertre, S.1
Ulens, C.2
Büttner, R.3
Fish, A.4
van Elk, R.5
Kendel, Y.6
-
183
-
-
52049099384
-
-
Peng C, Han Y, Sanders T, Chew G, Liu J, Hawrot E, et al. α4/7-conotoxin Lp1.1 is a novel antagonist of neuronal nicotinic acetylcholine receptors. Peptides 2008; doi:10.1016/ j.peptides.2008.05.028.
-
Peng C, Han Y, Sanders T, Chew G, Liu J, Hawrot E, et al. α4/7-conotoxin Lp1.1 is a novel antagonist of neuronal nicotinic acetylcholine receptors. Peptides 2008; doi:10.1016/ j.peptides.2008.05.028.
-
-
-
-
184
-
-
0038711752
-
α-Conotoxins PnIA and [A10L]PnIA stabilize different states of the α7-L247T nicotinic acetylcholine receptor
-
Hogg RC, Hopping G, Alewood PF, Adams DJ, Bertrand D. α-Conotoxins PnIA and [A10L]PnIA stabilize different states of the α7-L247T nicotinic acetylcholine receptor. J Biol Chem 2003; 278: 26908-14.
-
(2003)
J Biol Chem
, vol.278
, pp. 26908-26914
-
-
Hogg, R.C.1
Hopping, G.2
Alewood, P.F.3
Adams, D.J.4
Bertrand, D.5
-
185
-
-
3042566993
-
Structure-activity relationships of α-conotoxins targeting neuronal nicotinic acetylcholine receptors
-
Millard EL, Daly NL, Craik DJ. Structure-activity relationships of α-conotoxins targeting neuronal nicotinic acetylcholine receptors. Eur J Biochem 2004; 271: 2320-6.
-
(2004)
Eur J Biochem
, vol.271
, pp. 2320-2326
-
-
Millard, E.L.1
Daly, N.L.2
Craik, D.J.3
-
186
-
-
0028144775
-
Relationship between the binding sites for an α-conotoxin and snake venom neurotoxins in the nicotinic acetylcholine receptor from Torpedo californica
-
Utkin YN, Kobayashi Y, Hucho F, Tsetlin VI. Relationship between the binding sites for an α-conotoxin and snake venom neurotoxins in the nicotinic acetylcholine receptor from Torpedo californica. Toxicon 1994; 32: 1153-7.
-
(1994)
Toxicon
, vol.32
, pp. 1153-1157
-
-
Utkin, Y.N.1
Kobayashi, Y.2
Hucho, F.3
Tsetlin, V.I.4
-
187
-
-
0028346433
-
Glycosylation sites selectively interfere with α-toxin binding to the nicotinic acetylcholine receptor
-
Kreienkamp HJ, Sine SM, Maeda RK, Taylor P. Glycosylation sites selectively interfere with α-toxin binding to the nicotinic acetylcholine receptor. J Biol Chem 1994; 269: 8108-14.
-
(1994)
J Biol Chem
, vol.269
, pp. 8108-8114
-
-
Kreienkamp, H.J.1
Sine, S.M.2
Maeda, R.K.3
Taylor, P.4
-
188
-
-
0029085766
-
Molecular dissection of subunit interfaces in the acetylcholine receptor: Identification of determinants of α-conotoxin M1 selectivity
-
Sine SM, Kreienkamp HJ, Bren N, Maeda R, Taylor P. Molecular dissection of subunit interfaces in the acetylcholine receptor: Identification of determinants of α-conotoxin M1 selectivity. Neuron 1995; 15: 205-11.
-
(1995)
Neuron
, vol.15
, pp. 205-211
-
-
Sine, S.M.1
Kreienkamp, H.J.2
Bren, N.3
Maeda, R.4
Taylor, P.5
-
189
-
-
0033580614
-
Structure of the agonist-binding sites of the Torpedo nicotinic acetylcholine receptor: Affinity-labeling and mutational analyses identify γTyr-111/δArg-113 as antagonist affinity determinants
-
Chiara DC, Xie Y, Cohen JB. Structure of the agonist-binding sites of the Torpedo nicotinic acetylcholine receptor: Affinity-labeling and mutational analyses identify γTyr-111/δArg-113 as antagonist affinity determinants. Biochemistry 1999; 38: 6689-98.
-
(1999)
Biochemistry
, vol.38
, pp. 6689-6698
-
-
Chiara, D.C.1
Xie, Y.2
Cohen, J.B.3
-
190
-
-
31144439038
-
Striatal α6* nicotinic acetylcholine receptors: Potential targets for Parkinson's disease therapy
-
Quik M, McIntosh JM. Striatal α6* nicotinic acetylcholine receptors: Potential targets for Parkinson's disease therapy. J Pharmacol Exp Ther 2006; 316: 481-9.
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 481-489
-
-
Quik, M.1
McIntosh, J.M.2
-
191
-
-
34548692998
-
The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum
-
Grady SR, Salminen O, Laverty DC, Whiteaker P, McIntosh JM, Collins AC, et al. The subtypes of nicotinic acetylcholine receptors on dopaminergic terminals of mouse striatum. Biochem Pharmacol 2007; 74: 1235-46.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 1235-1246
-
-
Grady, S.R.1
Salminen, O.2
Laverty, D.C.3
Whiteaker, P.4
McIntosh, J.M.5
Collins, A.C.6
-
192
-
-
45549086824
-
Amino acid residues that confer high selectivity of the α6 nicotinic acetylcholine receptor subunit to α-conotoxin MII[S4A,E11A,L15A]
-
Azam L, Yoshikami D, McIntosh JM. Amino acid residues that confer high selectivity of the α6 nicotinic acetylcholine receptor subunit to α-conotoxin MII[S4A,E11A,L15A]. J Biol Chem 2008; 283: 11625-32.
-
(2008)
J Biol Chem
, vol.283
, pp. 11625-11632
-
-
Azam, L.1
Yoshikami, D.2
McIntosh, J.M.3
-
193
-
-
33744918558
-
-
Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists. J Biol Chem 2006; 281: 14136-43.
-
Armishaw CJ, Daly NL, Nevin ST, Adams DJ, Craik DJ, Alewood PF. α-Selenoconotoxins, a new class of potent α7 neuronal nicotinic receptor antagonists. J Biol Chem 2006; 281: 14136-43.
-
-
-
-
194
-
-
54349103998
-
-
Innocent N, Livingstone PD, Hone A, Kimura A, Young T, Whiteaker P, et al. α-Conotoxin ArIBV11L,V16D is a potent and selective antagonist at rat and human native α7 nicotinic acetylcholine receptors. J Pharmacol Exp Ther 2008; doi:10.1124/jpet.108.142943.
-
Innocent N, Livingstone PD, Hone A, Kimura A, Young T, Whiteaker P, et al. α-Conotoxin ArIBV11L,V16D is a potent and selective antagonist at rat and human native α7 nicotinic acetylcholine receptors. J Pharmacol Exp Ther 2008; doi:10.1124/jpet.108.142943.
-
-
-
-
195
-
-
33747626073
-
3H]norepinephrine release from mouse hippocampal synaptosomes
-
3H]norepinephrine release from mouse hippocampal synaptosomes. Mol Pharmacol 2006; 70: 967-76.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 967-976
-
-
Azam, L.1
McIntosh, J.M.2
-
196
-
-
33748788287
-
Determinants of α-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor beta subunit
-
Shiembob DL, Roberts RL, Luetje CW, McIntosh JM. Determinants of α-conotoxin BuIA selectivity on the nicotinic acetylcholine receptor beta subunit. Biochemistry 2006; 45: 11200-7.
-
(2006)
Biochemistry
, vol.45
, pp. 11200-11207
-
-
Shiembob, D.L.1
Roberts, R.L.2
Luetje, C.W.3
McIntosh, J.M.4
-
197
-
-
26844476004
-
α-Conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurones
-
Satkunanathan N, Livett B, Gayler K, Sandall D, Down J, Khalil Z. α-Conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurones. Brain Res 2005; 1059: 149-58
-
(2005)
Brain Res
, vol.1059
, pp. 149-158
-
-
Satkunanathan, N.1
Livett, B.2
Gayler, K.3
Sandall, D.4
Down, J.5
Khalil, Z.6
-
198
-
-
36348987984
-
Are α9α10 nicotinic acetylcholine receptors a pain target for α-conotoxins?
-
Nevin ST, Clark RJ, Klimis H, Christie MJ, Craik DJ, Adams DJ. Are α9α10 nicotinic acetylcholine receptors a pain target for α-conotoxins? Mol Pharmacol 2007; 72: 1406-10.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 1406-1410
-
-
Nevin, S.T.1
Clark, R.J.2
Klimis, H.3
Christie, M.J.4
Craik, D.J.5
Adams, D.J.6
-
199
-
-
2642577647
-
Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry
-
Jakubowski JA, Keays DA, Kelley WP, Sandall DW, Bingham JP, Livett BG, et al. Determining sequences and post-translational modifications of novel conotoxins in Conus victoriae using cDNA sequencing and mass spectrometry. J Mass Spectrom 2004; 39: 548-57.
-
(2004)
J Mass Spectrom
, vol.39
, pp. 548-557
-
-
Jakubowski, J.A.1
Keays, D.A.2
Kelley, W.P.3
Sandall, D.W.4
Bingham, J.P.5
Livett, B.G.6
-
200
-
-
33646470012
-
Fourier transform mass spectrometry: A powerful tool for toxin analysis
-
Quinton L, Le Caër JP, Vinh J, Gilles N, Chamot-Rooke J. Fourier transform mass spectrometry: A powerful tool for toxin analysis. Toxicon 2006; 47: 715-26.
-
(2006)
Toxicon
, vol.47
, pp. 715-726
-
-
Quinton, L.1
Le Caër, J.P.2
Vinh, J.3
Gilles, N.4
Chamot-Rooke, J.5
-
201
-
-
0021755618
-
Conotoxin GI: Disulfide bridges, synthesis, and preparation of iodinated derivatives
-
Gray WR, Luque FA, Galyean R, Atherton E, Sheppard RC, Stone BL, et al. Conotoxin GI: Disulfide bridges, synthesis, and preparation of iodinated derivatives. Biochemistry 1984; 23: 2796-802.
-
(1984)
Biochemistry
, vol.23
, pp. 2796-2802
-
-
Gray, W.R.1
Luque, F.A.2
Galyean, R.3
Atherton, E.4
Sheppard, R.C.5
Stone, B.L.6
-
203
-
-
0037375696
-
A comparative study on selectivity of α-conotoxins GI and ImI using their synthetic analogues and derivatives
-
Kasheverov IE, Zhmak MN, Maslennikov IV, Utkin YN, Tsetlin VI. A comparative study on selectivity of α-conotoxins GI and ImI using their synthetic analogues and derivatives. Neurochem Res 2003; 28: 599-606.
-
(2003)
Neurochem Res
, vol.28
, pp. 599-606
-
-
Kasheverov, I.E.1
Zhmak, M.N.2
Maslennikov, I.V.3
Utkin, Y.N.4
Tsetlin, V.I.5
-
204
-
-
0033608956
-
Stability and structure-forming properties of the two disulfide bonds of α-conotoxin GI
-
Kaerner A, Rabenstein DL. Stability and structure-forming properties of the two disulfide bonds of α-conotoxin GI. Biochemistry 1999; 38: 5459-70.
-
(1999)
Biochemistry
, vol.38
, pp. 5459-5470
-
-
Kaerner, A.1
Rabenstein, D.L.2
-
205
-
-
0033554391
-
NMR solution conformation of an antitoxic analogue of α-conotoxin GI: Identification of a common nicotinic acetylcholine receptor α1-subunit binding surface for small ligands and α-conotoxins
-
Mok KH, Han KH. NMR solution conformation of an antitoxic analogue of α-conotoxin GI: Identification of a common nicotinic acetylcholine receptor α1-subunit binding surface for small ligands and α-conotoxins. Biochemistry 1999; 38: 11895-904.
-
(1999)
Biochemistry
, vol.38
, pp. 11895-11904
-
-
Mok, K.H.1
Han, K.H.2
-
206
-
-
0026348466
-
Factors governing selective formation of specific disulfides in synthetic variants of α-conotoxin
-
Zhang R, Snyder G. Factors governing selective formation of specific disulfides in synthetic variants of α-conotoxin. Biochemistry 1991; 30: 11343-8.
-
(1991)
Biochemistry
, vol.30
, pp. 11343-11348
-
-
Zhang, R.1
Snyder, G.2
-
207
-
-
0034819433
-
Photoactivatable α-conotoxins reveal contacts with all subunits as well as antagonist-induced rearrangements in the Torpedo californica acetylcholine receptor
-
Kasheverov I, Rozhkova A, Zhmak M, Utkin Y, Ivanov V, Tsetlin VI. Photoactivatable α-conotoxins reveal contacts with all subunits as well as antagonist-induced rearrangements in the Torpedo californica acetylcholine receptor. Eur J Biochem 2001; 268: 3664-73.
-
(2001)
Eur J Biochem
, vol.268
, pp. 3664-3673
-
-
Kasheverov, I.1
Rozhkova, A.2
Zhmak, M.3
Utkin, Y.4
Ivanov, V.5
Tsetlin, V.I.6
-
208
-
-
0038970199
-
Study of solid-phase catalytic isotopic exchange of hydrogen in α-conotoxin G1 under the effect of spill-over-tritium
-
Zolotarev YA, Bocharov EV, Dadayan AK, Kasheverov IE, Zhmak MN, Maslennikov IV, et al. Study of solid-phase catalytic isotopic exchange of hydrogen in α-conotoxin G1 under the effect of spill-over-tritium. Bioorg Khim 2000; 26: 587-92.
-
(2000)
Bioorg Khim
, vol.26
, pp. 587-592
-
-
Zolotarev, Y.A.1
Bocharov, E.V.2
Dadayan, A.K.3
Kasheverov, I.E.4
Zhmak, M.N.5
Maslennikov, I.V.6
-
209
-
-
0030665276
-
Characterization of α-conotoxin interactions with the nicotinic acetylcholine receptor and monoclonal antibodies
-
Ashcom JD, Stiles BG. Characterization of α-conotoxin interactions with the nicotinic acetylcholine receptor and monoclonal antibodies. Biochem J 1997; 328: 245-50.
-
(1997)
Biochem J
, vol.328
, pp. 245-250
-
-
Ashcom, J.D.1
Stiles, B.G.2
-
210
-
-
33745296428
-
Reversible sequential-binding probe receptor-ligand interactions in single cells
-
Schreiter C, Gjoni M, Hovius R, Martinez KL, Segura JM, Vogel H. Reversible sequential-binding probe receptor-ligand interactions in single cells. Chembiochem 2005; 6: 2187-94.
-
(2005)
Chembiochem
, vol.6
, pp. 2187-2194
-
-
Schreiter, C.1
Gjoni, M.2
Hovius, R.3
Martinez, K.L.4
Segura, J.M.5
Vogel, H.6
-
212
-
-
4744351111
-
α-Conotoxin residues that interact at close range with γ-tyrosine-111 and mutant δ-tyrosine-113 on the Torpedo nicotinic acetylcholine receptor
-
Velez-Carrasco W, Valdes S, Agresar L, Lettich A, Guerra AY, Hann RM. α-Conotoxin residues that interact at close range with γ-tyrosine-111 and mutant δ-tyrosine-113 on the Torpedo nicotinic acetylcholine receptor. Biochemistry 2004; 43: 12700-8.
-
(2004)
Biochemistry
, vol.43
, pp. 12700-12708
-
-
Velez-Carrasco, W.1
Valdes, S.2
Agresar, L.3
Lettich, A.4
Guerra, A.Y.5
Hann, R.M.6
-
213
-
-
0013324178
-
Synthesis and immunological studies of α-conotoxin chimera containing an immunodominant epitope from the 268-284 region of HSV gD protein
-
Mezo G, Drakopoulou E, Paal V, Rajnavolgyi E, Vita C, Hudecz F. Synthesis and immunological studies of α-conotoxin chimera containing an immunodominant epitope from the 268-284 region of HSV gD protein. J Pept Res 2000; 55: 7-17.
-
(2000)
J Pept Res
, vol.55
, pp. 7-17
-
-
Mezo, G.1
Drakopoulou, E.2
Paal, V.3
Rajnavolgyi, E.4
Vita, C.5
Hudecz, F.6
-
214
-
-
0034093622
-
Synthesis and antibody recognition of mucin 1 (MUC1)-α-conotoxin chimera
-
Drakopoulou E, Uray K, Mezo G, Price MR, Vita C, Hudecz F. Synthesis and antibody recognition of mucin 1 (MUC1)-α-conotoxin chimera. J Pept Sci 2000; 6: 175-85.
-
(2000)
J Pept Sci
, vol.6
, pp. 175-185
-
-
Drakopoulou, E.1
Uray, K.2
Mezo, G.3
Price, M.R.4
Vita, C.5
Hudecz, F.6
-
215
-
-
0035968281
-
Site-specific charge interactions of α-conotoxin MI with the nicotinic acetylcholine receptor
-
Papineni RV, Sanchez JU, Baksi K, Willcockson IU, Pedersen SE. Site-specific charge interactions of α-conotoxin MI with the nicotinic acetylcholine receptor. J Biol Chem 2001; 276: 23589-98.
-
(2001)
J Biol Chem
, vol.276
, pp. 23589-23598
-
-
Papineni, R.V.1
Sanchez, J.U.2
Baksi, K.3
Willcockson, I.U.4
Pedersen, S.E.5
-
216
-
-
0031967095
-
Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to α-conotoxin M1 binding
-
Sugiyama N, Marchot P, Kawanishi C, Osaka H, Molles B, Sine SM, et al. Residues at the subunit interfaces of the nicotinic acetylcholine receptor that contribute to α-conotoxin M1 binding. Mol Pharmacol 1998; 53: 787-94.
-
(1998)
Mol Pharmacol
, vol.53
, pp. 787-794
-
-
Sugiyama, N.1
Marchot, P.2
Kawanishi, C.3
Osaka, H.4
Molles, B.5
Sine, S.M.6
-
218
-
-
0034724745
-
Hydrophobic pairwise interactions stabilize α-conotoxin MI in the muscle acetylcholine receptor binding site
-
Bren N, Sine SM. Hydrophobic pairwise interactions stabilize α-conotoxin MI in the muscle acetylcholine receptor binding site. J Biol Chem 2000; 275: 12692-700.
-
(2000)
J Biol Chem
, vol.275
, pp. 12692-12700
-
-
Bren, N.1
Sine, S.M.2
-
219
-
-
0032760184
-
Controlled syntheses of natural and disul-fide-mispaired regioisomers of α-conotoxin SI
-
Hargittai B, Barany G. Controlled syntheses of natural and disul-fide-mispaired regioisomers of α-conotoxin SI. J Pept Res 1999; 54: 468-79.
-
(1999)
J Pept Res
, vol.54
, pp. 468-479
-
-
Hargittai, B.1
Barany, G.2
-
220
-
-
0034649554
-
Chemical syntheses and biological activities of lactam analogues of α-conotoxin SI
-
Hargittai B, Sole NA, Groebe DR, Abramson SN, Barany G. Chemical syntheses and biological activities of lactam analogues of α-conotoxin SI. J Med Chem 2000; 43: 4787-92.
-
(2000)
J Med Chem
, vol.43
, pp. 4787-4792
-
-
Hargittai, B.1
Sole, N.A.2
Groebe, D.R.3
Abramson, S.N.4
Barany, G.5
-
221
-
-
0344359749
-
Functional determinants by which snake and cone snail toxins block the α7 neuronal nicotinic acetylcholine receptors
-
Servent D, Thanh HL, Antil S, Bertrand D, Corringer PJ, Changeux JP, et al. Functional determinants by which snake and cone snail toxins block the α7 neuronal nicotinic acetylcholine receptors. J Physiol (Paris) 1998; 92: 107-11.
-
(1998)
J Physiol (Paris)
, vol.92
, pp. 107-111
-
-
Servent, D.1
Thanh, H.L.2
Antil, S.3
Bertrand, D.4
Corringer, P.J.5
Changeux, J.P.6
-
222
-
-
0033013141
-
Minimal conformation of the α-conotoxin ImI for the α7 neuronal nicotinic acetylcholine receptor recognition: Correlated CD, NMR and binding studies
-
Lamthanh H, Jegou-Matheron C, Servent D, Menez A, Lancelin JM. Minimal conformation of the α-conotoxin ImI for the α7 neuronal nicotinic acetylcholine receptor recognition: Correlated CD, NMR and binding studies. FEBS Lett 1999; 454: 293-8.
-
(1999)
FEBS Lett
, vol.454
, pp. 293-298
-
-
Lamthanh, H.1
Jegou-Matheron, C.2
Servent, D.3
Menez, A.4
Lancelin, J.M.5
-
223
-
-
26844525932
-
Effect of C-terminal amidation on folding and disulfide-pairing of α-conotoxin ImI
-
Kang TS, Vivekanandan S, Jois SD, Kini RM. Effect of C-terminal amidation on folding and disulfide-pairing of α-conotoxin ImI. Angew Chem Int Ed Engl 2005; 44: 6333-7.
-
(2005)
Angew Chem Int Ed Engl
, vol.44
, pp. 6333-6337
-
-
Kang, T.S.1
Vivekanandan, S.2
Jois, S.D.3
Kini, R.M.4
-
224
-
-
0033406665
-
Aromatic substitutions in α-conotoxin ImI. Synthesis of iodinated photoactivatable derivative
-
Utkin YN, Zhmak MN, Methfessel C, Tsetlin VI. Aromatic substitutions in α-conotoxin ImI. Synthesis of iodinated photoactivatable derivative. Toxicon 1999; 37: 1683-95.
-
(1999)
Toxicon
, vol.37
, pp. 1683-1695
-
-
Utkin, Y.N.1
Zhmak, M.N.2
Methfessel, C.3
Tsetlin, V.I.4
-
225
-
-
0032080235
-
Structural elements in α-conotoxin ImI essential for binding to neuronal α7 receptors
-
Quiram, P.A. and Sine, S.M. Structural elements in α-conotoxin ImI essential for binding to neuronal α7 receptors. J Biol Chem 1998; 273: 11007-11.
-
(1998)
J Biol Chem
, vol.273
, pp. 11007-11011
-
-
Quiram, P.A.1
Sine, S.M.2
-
226
-
-
0034671348
-
Structure-activity relationships in a peptidic α7 nicotinic acetylcholine receptor antagonist
-
Rogers JP, Luginbuhl P, Pemberton K, Harty P, Wemmer DE, Stevens RC. Structure-activity relationships in a peptidic α7 nicotinic acetylcholine receptor antagonist. J Mol Biol 2000; 304: 911-26.
-
(2000)
J Mol Biol
, vol.304
, pp. 911-926
-
-
Rogers, J.P.1
Luginbuhl, P.2
Pemberton, K.3
Harty, P.4
Wemmer, D.E.5
Stevens, R.C.6
-
227
-
-
21844432145
-
Nicotinic acetylcholine receptor subunits and associated proteins in human sperm
-
Kumar P, Meizel S. Nicotinic acetylcholine receptor subunits and associated proteins in human sperm. J Biol Chem 2005; 280: 25928-35
-
(2005)
J Biol Chem
, vol.280
, pp. 25928-25935
-
-
Kumar, P.1
Meizel, S.2
-
228
-
-
0033538459
-
Pairwise interactions between neuronal α7 acetylcholine receptors and α-conotoxin ImI
-
Quiram PA, Jones JJ, Sine SM. Pairwise interactions between neuronal α7 acetylcholine receptors and α-conotoxin ImI. J Biol Chem 1999; 274: 19517-24.
-
(1999)
J Biol Chem
, vol.274
, pp. 19517-19524
-
-
Quiram, P.A.1
Jones, J.J.2
Sine, S.M.3
-
229
-
-
22144470470
-
Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant
-
Celie PH, Kasheverov IE, Mordvintsev DY, Hogg RC, van Nierop P, van Elk R, et al. Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an α-conotoxin PnIA variant. Nat Struct Mol Biol 2005; 12: 582-8.
-
(2005)
Nat Struct Mol Biol
, vol.12
, pp. 582-588
-
-
Celie, P.H.1
Kasheverov, I.E.2
Mordvintsev, D.Y.3
Hogg, R.C.4
van Nierop, P.5
van Elk, R.6
-
230
-
-
52449124819
-
Molecular engineering of conotoxins: The importance of loop size to α-conotoxin structure and function
-
Jin AH, Daly NL, Nevin ST, Wang CI, Dutertre S, Lewis RJ, et al. Molecular engineering of conotoxins: The importance of loop size to α-conotoxin structure and function. J Med Chem 2008; 51: 5575-84.
-
(2008)
J Med Chem
, vol.51
, pp. 5575-5584
-
-
Jin, A.H.1
Daly, N.L.2
Nevin, S.T.3
Wang, C.I.4
Dutertre, S.5
Lewis, R.J.6
-
233
-
-
0037083377
-
Distribution and pharmacology of α6-containing nicotinic acetylcholine receptors analyzed with mutant mice
-
Champtiaux N, Han ZY, Bessis A, Rossi FM, Zoli M, Marubio L, et al. Distribution and pharmacology of α6-containing nicotinic acetylcholine receptors analyzed with mutant mice. J Neurosci 2002; 22: 1208-17.
-
(2002)
J Neurosci
, vol.22
, pp. 1208-1217
-
-
Champtiaux, N.1
Han, Z.Y.2
Bessis, A.3
Rossi, F.M.4
Zoli, M.5
Marubio, L.6
-
234
-
-
0036550662
-
-
Whiteaker P, Peterson CG, Xu W, McIntosh JM, Paylor R, Beaud et al., et al. Involvement of the α3 subunit in central nicotinic binding populations. J. Neurosci 2002; 22: 2522-9.
-
Whiteaker P, Peterson CG, Xu W, McIntosh JM, Paylor R, Beaud et al., et al. Involvement of the α3 subunit in central nicotinic binding populations. J. Neurosci 2002; 22: 2522-9.
-
-
-
-
235
-
-
16244381402
-
The subunit composition and pharmacology of α-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay
-
Salminen O, Whiteaker P, Grady SR, Collins AC, McIntosh JM, Marks MJ. The subunit composition and pharmacology of α-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay. Neuropharmacology 2005; 48: 696-705.
-
(2005)
Neuropharmacology
, vol.48
, pp. 696-705
-
-
Salminen, O.1
Whiteaker, P.2
Grady, S.R.3
Collins, A.C.4
McIntosh, J.M.5
Marks, M.J.6
-
236
-
-
34347364721
-
Pharmacology of α-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice
-
Salminen O, Drapeau JA, McIntosh JM, Collins AC, Marks MJ, Grady SR. Pharmacology of α-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice. Mol Pharmacol 2007; 71: 1563-71.
-
(2007)
Mol Pharmacol
, vol.71
, pp. 1563-1571
-
-
Salminen, O.1
Drapeau, J.A.2
McIntosh, J.M.3
Collins, A.C.4
Marks, M.J.5
Grady, S.R.6
-
237
-
-
34347218938
-
Nigrostriatal damage preferentially decreases a subpopulation of α6β2* nAChRs in mouse, monkey, and Parkinson's disease striatum
-
Bordia T, Grady SR, McIntosh JM, Quik M. Nigrostriatal damage preferentially decreases a subpopulation of α6β2* nAChRs in mouse, monkey, and Parkinson's disease striatum. Mol Pharmacol 2007; 72: 52-61.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 52-61
-
-
Bordia, T.1
Grady, S.R.2
McIntosh, J.M.3
Quik, M.4
-
238
-
-
44649150192
-
Adult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure
-
Doura MB, Gold AB, Keller AB, Perry DC. Adult and periadolescent rats differ in expression of nicotinic cholinergic receptor subtypes and in the response of these subtypes to chronic nicotine exposure. Brain Res 2008; 1215: 40-52.
-
(2008)
Brain Res
, vol.1215
, pp. 40-52
-
-
Doura, M.B.1
Gold, A.B.2
Keller, A.B.3
Perry, D.C.4
-
239
-
-
25444448796
-
Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII
-
Clark RJ, Fischer H, Dempster L, Daly NL, Rosengren KJ, Nevin ST, et al. Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII. Proc Natl Acad Sci USA 2005; 102: 13767-72.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13767-13772
-
-
Clark, R.J.1
Fischer, H.2
Dempster, L.3
Daly, N.L.4
Rosengren, K.J.5
Nevin, S.T.6
-
240
-
-
33845197219
-
Synthesis of fluorescent analogs of α-conotoxin MII
-
Vishwanath VA, McIntosh JM. Synthesis of fluorescent analogs of α-conotoxin MII. Bioconjug Chem 2006; 17: 1612-7.
-
(2006)
Bioconjug Chem
, vol.17
, pp. 1612-1617
-
-
Vishwanath, V.A.1
McIntosh, J.M.2
-
241
-
-
1542267785
-
Determinants of potency on α-conotoxin MII, a peptide antagonist of neuronal nicotinic receptors
-
Everhart D, Cartier GE, Malhotra A, Gomes AV, McIntosh JM, Luetje CW. Determinants of potency on α-conotoxin MII, a peptide antagonist of neuronal nicotinic receptors. Biochemistry 2004; 43: 2732-7.
-
(2004)
Biochemistry
, vol.43
, pp. 2732-2737
-
-
Everhart, D.1
Cartier, G.E.2
Malhotra, A.3
Gomes, A.V.4
McIntosh, J.M.5
Luetje, C.W.6
-
242
-
-
0344406263
-
Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII
-
Blanchfield JT, Dutton JL, Hogg RC, Gallagher OP, Craik DJ, Jones A, et al. Synthesis, structure elucidation, in vitro biological activity, toxicity, and Caco-2 cell permeability of lipophilic analogues of α-conotoxin MII. J Med Chem 2003; 46: 1266-72.
-
(2003)
J Med Chem
, vol.46
, pp. 1266-1272
-
-
Blanchfield, J.T.1
Dutton, J.L.2
Hogg, R.C.3
Gallagher, O.P.4
Craik, D.J.5
Jones, A.6
-
243
-
-
34547106305
-
Oral absorption and in vivo biodistribution of a α-conotoxin MII and a lipidic analogue
-
Blanchfield JT, Gallagher OP, Cros C, Lewis RJ, Alewood PF, Toth I. Oral absorption and in vivo biodistribution of a α-conotoxin MII and a lipidic analogue. Biochem Biophys Res Commun 2007; 361: 97-102
-
(2007)
Biochem Biophys Res Commun
, vol.361
, pp. 97-102
-
-
Blanchfield, J.T.1
Gallagher, O.P.2
Cros, C.3
Lewis, R.J.4
Alewood, P.F.5
Toth, I.6
-
244
-
-
44249110008
-
125I-α-conotoxin ArIB[V11L;V16A], a selective α7 nicotinic acetylcholine receptor antagonist
-
125I-α-conotoxin ArIB[V11L;V16A], a selective α7 nicotinic acetylcholine receptor antagonist. J Pharmacol Exp Ther 2008; 325: 910-9.
-
(2008)
J Pharmacol Exp Ther
, vol.325
, pp. 910-919
-
-
Whiteaker, P.1
Marks, M.J.2
Christensen, S.3
Dowell, C.4
Collins, A.C.5
McIntosh, J.M.6
-
245
-
-
34548643963
-
Chemical modification of conotoxins to improve stability and activity. ACS
-
Craik DJ, Adams DJ. Chemical modification of conotoxins to improve stability and activity. ACS Chem Biol 2007; 2: 457-68.
-
(2007)
Chem Biol
, vol.2
, pp. 457-468
-
-
Craik, D.J.1
Adams, D.J.2
-
247
-
-
0032079457
-
Identification of residues in the neuronal α7 acetylcholine receptor that confer selectivity for conotoxin ImI
-
Quiram PA, Sine SM. Identification of residues in the neuronal α7 acetylcholine receptor that confer selectivity for conotoxin ImI. J Biol Chem 1998; 273: 11001-6.
-
(1998)
J Biol Chem
, vol.273
, pp. 11001-11006
-
-
Quiram, P.A.1
Sine, S.M.2
-
248
-
-
0036891560
-
The nicotinic receptor ligand binding domain
-
Sine SM. The nicotinic receptor ligand binding domain. J Neurobiol 2002; 53: 431-46.
-
(2002)
J Neurobiol
, vol.53
, pp. 431-446
-
-
Sine, S.M.1
-
249
-
-
0035902187
-
A glia-derived acetylcholine-binding protein that modulates synaptic transmission
-
Smit AB, Syed NI, Schaap D, van Minnen J, Klumperman J, Kits KS, et al. A glia-derived acetylcholine-binding protein that modulates synaptic transmission. Nature 2001; 411: 261-8.
-
(2001)
Nature
, vol.411
, pp. 261-268
-
-
Smit, A.B.1
Syed, N.I.2
Schaap, D.3
van Minnen, J.4
Klumperman, J.5
Kits, K.S.6
-
250
-
-
0035902009
-
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
-
Brejc K, van Dijk WJ, Klaassen RV, Schuurmans M, van Der Oost J, Smit AB, et al. Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors. Nature 2001; 411: 269-76.
-
(2001)
Nature
, vol.411
, pp. 269-276
-
-
Brejc, K.1
van Dijk, W.J.2
Klaassen, R.V.3
Schuurmans, M.4
van Der Oost, J.5
Smit, A.B.6
-
251
-
-
2642560397
-
Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica
-
Hansen SB, Talley TT, Radic Z, Taylor P. Structural and ligand recognition characteristics of an acetylcholine-binding protein from Aplysia californica. J Biol Chem 2004; 279: 24197-202.
-
(2004)
J Biol Chem
, vol.279
, pp. 24197-24202
-
-
Hansen, S.B.1
Talley, T.T.2
Radic, Z.3
Taylor, P.4
-
252
-
-
22144466847
-
Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors
-
Celie PH, Klaassen RV, van Rossum-Fikkert SE, van Elk R, van Nierop P, Smit AB, et al. Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors. J Biol Chem 2005; 280: 26457-66.
-
(2005)
J Biol Chem
, vol.280
, pp. 26457-26466
-
-
Celie, P.H.1
Klaassen, R.V.2
van Rossum-Fikkert, S.E.3
van Elk, R.4
van Nierop, P.5
Smit, A.B.6
-
253
-
-
33645384472
-
Natural α-conotoxins and their synthetic analogues in study of nicotinic acetylcholine receptors
-
Kasheverov IE, Utlin YN, Tsetlin VI. Natural α-conotoxins and their synthetic analogues in study of nicotinic acetylcholine receptors. Russ J Bioorg Chem 2006; 32: 103-115.
-
(2006)
Russ J Bioorg Chem
, vol.32
, pp. 103-115
-
-
Kasheverov, I.E.1
Utlin, Y.N.2
Tsetlin, V.I.3
-
254
-
-
27144473613
-
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
-
Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Taylor P, Bourne Y. Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations. EMBO J 2005; 24: 3635-46.
-
(2005)
EMBO J
, vol.24
, pp. 3635-3646
-
-
Hansen, S.B.1
Sulzenbacher, G.2
Huxford, T.3
Marchot, P.4
Taylor, P.5
Bourne, Y.6
-
255
-
-
33644870155
-
Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP
-
Ulens C, Hogg RC, Celie PH, Bertrand D, Tsetlin V, Smit AB, et al. Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP. Proc Natl Acad Sci USA 2006; 103: 3615-20.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 3615-3620
-
-
Ulens, C.1
Hogg, R.C.2
Celie, P.H.3
Bertrand, D.4
Tsetlin, V.5
Smit, A.B.6
-
256
-
-
14844300820
-
Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence
-
Gao F, Bren N, Burghardt TP, Hansen S, Henchman RH, Taylor P, et al. Agonist-mediated conformational changes in acetylcholine-binding protein revealed by simulation and intrinsic tryptophan fluorescence. J Biol Chem 2005; 280: 8443-51.
-
(2005)
J Biol Chem
, vol.280
, pp. 8443-8451
-
-
Gao, F.1
Bren, N.2
Burghardt, T.P.3
Hansen, S.4
Henchman, R.H.5
Taylor, P.6
-
257
-
-
13444271681
-
Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution
-
Unwin N. Refined structure of the nicotinic acetylcholine receptor at 4 Å resolution. J Mol Biol 2005; 346: 967-89.
-
(2005)
J Mol Biol
, vol.346
, pp. 967-989
-
-
Unwin, N.1
|