αconotoxin Arenatus IB[V11L,V16D] is a potent and selective antagonist at rat and human native α7 nicotinic acetylcholine receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 2, 2008, Pages 529-537

  Innocent, Neal ^a   Livingstone, Phil D ^a   Hone, Arik ^b   Kimura, Atsuko ^a   Young, Tracey ^a   Whiteaker, Paul ^c   McIntosh, J Michael ^b   Wonnacott, Susan ^a  

^a University of Bath   (United Kingdom)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (5 CHLORO 2,4 DIMETHOXYPHENYL) 3 (5 METHYLISOXAZOL 3 YL)UREA; 3 (2 AZETIDINYLMETHOXY)PYRIDINE; 5 IODO 3 (2 AZETIDINYLMETHOXY)PYRIDINE; AR R17779; BICYCLO[2.2.2]OCTANE DERIVATIVE; BUNGAROTOXIN RECEPTOR; CHOLINE; CONOTOXIN; DOPAMINE; ISOXAZOLE DERIVATIVE; NICOTINE; PNU 120596; POTASSIUM CHLORIDE; SPIRO[1 AZABICYCLO[2.2.2]OCTANE 3,59 OXAZOLIDIN] 29 ONE; UNCLASSIFIED DRUG; 1-(5-CHLORO-2,4-DIMETHOXYPHENYL)-3-(5-METHYLISOXAZOL-3-YL)UREA; ALPHA CONOTOXIN IB, LEU(11), ASP(16); ALPHA-BUNGAROTOXIN RECEPTOR; ALPHA-CONOTOXIN IB, LEU(11), ASP(16)-; AR-R 17779; BRIDGED COMPOUND; CALCIUM; CARBANILAMIDE DERIVATIVE; EPIBATIDINE; FUSED HETEROCYCLIC RINGS; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PYRIDINE DERIVATIVE; SPIRO COMPOUND; SPIRO[1 AZABICYCLO[2.2.2]OCTANE 3,2' THIAZOLIDINE] 2' ONE;

ANIMAL CELL; ARTICLE; DOPAMINE RELEASE; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; XENOPUS LAEVIS; ANIMAL; CELL STRAIN; DRUG EFFECT; MALE; METABOLISM; PHYSIOLOGY; SECRETION; SPRAGUE DAWLEY RAT;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BRIDGED COMPOUNDS; CALCIUM; CHOLINE; CONOTOXINS; DOPAMINE; HUMANS; ISOXAZOLES; MALE; NICOTINIC ANTAGONISTS; PC12 CELLS; PHENYLUREA COMPOUNDS; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SPIRO COMPOUNDS;

EID: 54349103998     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.142943     Document Type: Article

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