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Volumn 4, Issue 4, 1996, Pages 417-423

The 1.1 Å crystal structure of the neuronal acetylcholine receptor antagonist, α-conotoxin PnIA from Conus pennaceus

Author keywords

Acetylcholine receptor antagonist; Crystal structure; Neurotoxin; conotoxin

Indexed keywords

CONUS PENNACEUS; GASTROPODA;

EID: 0030584684     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(96)00047-0     Document Type: Article
Times cited : (101)

References (35)
  • 1
    • 0025300052 scopus 로고
    • Diversity of Conus neuropeptides
    • Olivera, B.M., et al., & Cruz, L.J. (1990). Diversity of Conus neuropeptides. Science 249, 257-263.
    • (1990) Science , vol.249 , pp. 257-263
    • Olivera, B.M.1    Cruz, L.J.2
  • 4
    • 0021749660 scopus 로고
    • Purification and sequence of a presynaptic peptide toxin from Conus geographus venom
    • Olivera, B.M., McIntosh, J.M., Cruz, L.J., Luque, FA & Gray, W.R. (1984). Purification and sequence of a presynaptic peptide toxin from Conus geographus venom. Biochemistry 23, 5087-5090.
    • (1984) Biochemistry , vol.23 , pp. 5087-5090
    • Olivera, B.M.1    McIntosh, J.M.2    Cruz, L.J.3    Luque, F.A.4    Gray, W.R.5
  • 5
    • 0022373275 scopus 로고
    • Peptide neurotoxins from fish-hunting cone snails
    • Olivera, B.M., et al., & Cruz, L.J. (1985). Peptide neurotoxins from fish-hunting cone snails. Science 230, 1338-1343.
    • (1985) Science , vol.230 , pp. 1338-1343
    • Olivera, B.M.1    Cruz, L.J.2
  • 6
    • 0022359989 scopus 로고
    • Conus geographus toxins that discriminate between neuronal and muscle sodium channels
    • Cruz, L.J., et al., & Moczydlowski, E. (1985). Conus geographus toxins that discriminate between neuronal and muscle sodium channels. J. Biol. Chem. 260, 9280-9288.
    • (1985) J. Biol. Chem. , vol.260 , pp. 9280-9288
    • Cruz, L.J.1    Moczydlowski, E.2
  • 7
    • 0028173320 scopus 로고
    • δ-Conotoxin GmVIA, a novel peptide from the venom of Conus gloriamaris
    • Shon, K.J., et al., & Olivera, B.M. (1994). δ-Conotoxin GmVIA, a novel peptide from the venom of Conus gloriamaris. Biochemistry 33, 11420-11425.
    • (1994) Biochemistry , vol.33 , pp. 11420-11425
    • Shon, K.J.1    Olivera, B.M.2
  • 8
    • 0028168296 scopus 로고
    • New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors
    • Fainzilber, M., et al., & Zlotkin, E. (1994). New mollusc-specific α-conotoxins block Aplysia neuronal acetylcholine receptors. Biochemistry 33, 9523-9529.
    • (1994) Biochemistry , vol.33 , pp. 9523-9529
    • Fainzilber, M.1    Zlotkin, E.2
  • 9
    • 0025996975 scopus 로고
    • α-Conotoxins, small peptide probes of nicotinic acetylcholine receptors
    • Myers, R.A., et al., & Olivera, B.M. (1991). α-Conotoxins, small peptide probes of nicotinic acetylcholine receptors. Biochemistry 30, 9370-9377.
    • (1991) Biochemistry , vol.30 , pp. 9370-9377
    • Myers, R.A.1    Olivera, B.M.2
  • 10
    • 0028361574 scopus 로고
    • A nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin Iml
    • McIntosh, J.M., et al., & Olivera, B.M. (1994). A nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin Iml. J. Biol. Chem. 269, 16733-16739.
    • (1994) J. Biol. Chem. , vol.269 , pp. 16733-16739
    • McIntosh, J.M.1    Olivera, B.M.2
  • 11
    • 0028973580 scopus 로고
    • α-Conotoxin El, a new nicotinic acetylcholine receptor antagonist with novel selectivity
    • Martinez, J.S., et al., & McIntosh, J. M. (1995). α-Conotoxin El, a new nicotinic acetylcholine receptor antagonist with novel selectivity. Biochemistry 34, 14519-14526.
    • (1995) Biochemistry , vol.34 , pp. 14519-14526
    • Martinez, J.S.1    McIntosh, J.M.2
  • 12
    • 0024319437 scopus 로고
    • Solution structures of α-conotoxin Gl determined by two-dimensional NMR spectroscopy
    • Pardi, A., Galdes, A., Florance, J. & Maniconte, D. (1989). Solution structures of α-conotoxin Gl determined by two-dimensional NMR spectroscopy. Biochemistry 28, 5494-5501.
    • (1989) Biochemistry , vol.28 , pp. 5494-5501
    • Pardi, A.1    Galdes, A.2    Florance, J.3    Maniconte, D.4
  • 13
    • 0024384202 scopus 로고
    • 1H nuclear magnetic resonance spectroscopy and distance geometry calculations
    • 1H nuclear magnetic resonance spectroscopy and distance geometry calculations. Biochemistry 28, 4853-4860.
    • (1989) Biochemistry , vol.28 , pp. 4853-4860
    • Kobayashi, Y.1    Go, N.2
  • 14
    • 0028485498 scopus 로고
    • SnB: Crystal structure determination via Shake-and-Bake
    • Miller, R, Gallo, S.M., Khalak, H.G. & Weeks, C.M. (1994). SnB: Crystal structure determination via Shake-and-Bake. J. Appl. Cryst. 27, 613-621.
    • (1994) J. Appl. Cryst. , vol.27 , pp. 613-621
    • Miller, R.1    Gallo, S.M.2    Khalak, H.G.3    Weeks, C.M.4
  • 15
    • 0019443447 scopus 로고
    • The anatomy and taxonomy of protein structure
    • Richardson, J.S. (1981). The anatomy and taxonomy of protein structure. Adv. Protein Chem. 34, 167-339.
    • (1981) Adv. Protein Chem. , vol.34 , pp. 167-339
    • Richardson, J.S.1
  • 17
    • 0017700614 scopus 로고
    • Snake toxin secondary structure predictions: Structure activity relationships
    • Dufton, M.J. & Hider, R.C. (1977). Snake toxin secondary structure predictions: structure activity relationships. J. Mol. Biol. 115, 177-193.
    • (1977) J. Mol. Biol. , vol.115 , pp. 177-193
    • Dufton, M.J.1    Hider, R.C.2
  • 18
    • 0021812682 scopus 로고
    • A proposal for the structure of conotoxin - A potent antagonist of the nicotinic acetylcholine receptor
    • Hider, R.C. (1985). A proposal for the structure of conotoxin - a potent antagonist of the nicotinic acetylcholine receptor. FEBS Lett. 184, 181-184.
    • (1985) FEBS Lett. , vol.184 , pp. 181-184
    • Hider, R.C.1
  • 19
    • 0029119941 scopus 로고
    • Structure-activity relationships of nicotinic acetylcholine receptor agonists as potential treatments for dementia
    • Holladay, M.W., Lebold, S.A. & Lin, N.-H. (1995). Structure-activity relationships of nicotinic acetylcholine receptor agonists as potential treatments for dementia. Drug Dev. Res. 35, 191-213.
    • (1995) Drug Dev. Res. , vol.35 , pp. 191-213
    • Holladay, M.W.1    Lebold, S.A.2    Lin, N.-H.3
  • 20
    • 0028082093 scopus 로고
    • Neuronal acetylcholine receptors that bind α-bungarotoxin mediate neurite retraction in a calcium-dependent manner
    • Pugh, P.C. & Berg, D.K. (1994). Neuronal acetylcholine receptors that bind α-bungarotoxin mediate neurite retraction in a calcium-dependent manner. J. Neurosci. 14, 889-896.
    • (1994) J. Neurosci. , vol.14 , pp. 889-896
    • Pugh, P.C.1    Berg, D.K.2
  • 21
    • 0029096914 scopus 로고
    • Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors
    • McGehee, D.S., Heath, M.J.S., Gelber, S., Devay, P. & Role, L.W. (1995). Nicotine enhancement of fast excitatory synaptic transmission in CNS by presynaptic receptors. Science 269, 1692-1696.
    • (1995) Science , vol.269 , pp. 1692-1696
    • McGehee, D.S.1    Heath, M.J.S.2    Gelber, S.3    Devay, P.4    Role, L.W.5
  • 23
    • 0014432781 scopus 로고
    • Solvent content of protein crystals
    • Matthews, B.W. (1968). Solvent content of protein crystals. J. Mol. Biol. 33, 491-497.
    • (1968) J. Mol. Biol. , vol.33 , pp. 491-497
    • Matthews, B.W.1
  • 24
    • 0002452464 scopus 로고
    • Oscillation Data Reduction Program
    • (Sawyer, L., Isaacs, N. & Bailey, S., eds), SERC Daresbury Laboratory, Warrington, UK
    • Otwinowski, Z. (1993). Oscillation Data Reduction Program. In Proceedings of the CCP4 Study Weekend: Data Collection and Processing. (Sawyer, L., Isaacs, N. & Bailey, S., eds), pp. 55-62, SERC Daresbury Laboratory, Warrington, UK.
    • (1993) Proceedings of the CCP4 Study Weekend: Data Collection and Processing , pp. 55-62
    • Otwinowski, Z.1
  • 26
    • 0001431519 scopus 로고
    • DREADD - Data reduction and error analysis for single-crystal diffractometer data
    • Blessing, R.H. (1989). DREADD - Data reduction and error analysis for single-crystal diffractometer data. J. Appl. Cryst. 22, 396-397.
    • (1989) J. Appl. Cryst. , vol.22 , pp. 396-397
    • Blessing, R.H.1
  • 28
    • 79952608525 scopus 로고
    • Accurate bond lengths and angle parameters for X-ray protein structure refinement
    • Engh, R.A. & Huber, R. (1991). Accurate bond lengths and angle parameters for X-ray protein structure refinement. Acta Cryst. A 47, 392-400.
    • (1991) Acta Cryst. A , vol.47 , pp. 392-400
    • Engh, R.A.1    Huber, R.2
  • 29
    • 84889120137 scopus 로고
    • Improved methods for building protein models in electron density maps and the location of errors in these models
    • Jones, T.A., Zou, J.Y., Cowan, S.W. & Kjeldgaard, M. (1991). Improved methods for building protein models in electron density maps and the location of errors in these models. Acta Cryst. A 47, 110-119.
    • (1991) Acta Cryst. A , vol.47 , pp. 110-119
    • Jones, T.A.1    Zou, J.Y.2    Cowan, S.W.3    Kjeldgaard, M.4
  • 31
    • 0000243829 scopus 로고
    • PROCHECK: A program to check the stereochemical quality of protein structures
    • Laskowski, R.A., MacArthur, M.W., Moss, D.S. & Thornton, J.M. (1993). PROCHECK: A program to check the stereochemical quality of protein structures. J. Appl. Cryst. 26, 283-291.
    • (1993) J. Appl. Cryst. , vol.26 , pp. 283-291
    • Laskowski, R.A.1    MacArthur, M.W.2    Moss, D.S.3    Thornton, J.M.4
  • 32
    • 0017411710 scopus 로고
    • The protein data bank: A computer-based archival file for macromolecular structures
    • Bernstein, F.C., et al., & Tasumi, M. (1977). The protein data bank: a computer-based archival file for macromolecular structures. J. Mol. Biol. 112, 535-542.
    • (1977) J. Mol. Biol. , vol.112 , pp. 535-542
    • Bernstein, F.C.1    Tasumi, M.2
  • 34
    • 0026319199 scopus 로고
    • Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
    • Nicholls, A., Sharp, K.A. & Honig, B. (1991). Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11, 281-296.
    • (1991) Proteins , vol.11 , pp. 281-296
    • Nicholls, A.1    Sharp, K.A.2    Honig, B.3
  • 35
    • 0026597444 scopus 로고
    • Free R value: A novel statistical quantity for assessing the accuracy of crystal structures
    • Brünger, AT. (1992). Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. Nature 355, 472-475.
    • (1992) Nature , vol.355 , pp. 472-475
    • Brünger, A.T.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.