Allosteric α1-Adrenoreceptor Antagonism by the Conopeptide ρ-TIA

Journal of Biological Chemistry

Volumn 278, Issue 36, 2003, Pages 34451-34457

  Sharpe, Iain A ^a   Thomas, Linda ^a   Loughnan, Marion ^a   Motin, Leonid ^a   Palant, Elka ^b   Croker, Daniel E ^b   Alewood, Dianne ^b   Chen, Songhai ^c   Graham, Robert M ^c   Alewood, Paul F ^a   Adams, David J ^a   Lewis, Richard J ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b Xenome Ltd   (Australia)

^c VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; ASSOCIATION REACTIONS; DISSOCIATION; MOLECULAR STRUCTURE; POLYPEPTIDES;

SNAILS; VENOM;

BIOCHEMISTRY;

ALANINE; ALPHA 1 ADRENERGIC RECEPTOR; ARGININE; CONOPEPTIDE; CONOTOXIN; G PROTEIN COUPLED RECEPTOR; NORADRENALIN; PEPTIDE; PRAZOSIN; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG; CONOTOXIN RHO TIA; CONOTOXIN RHO-TIA; CYSTINE;

ALLOSTERISM; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; COMPETITIVE INHIBITION; DISSOCIATION; DRUG ANTAGONISM; GASTROPOD; LIGAND BINDING; MALE; MEDIATOR RELEASE; NEUROTRANSMITTER RELEASE; NONHUMAN; PEPTIDE ANALYSIS; PRIORITY JOURNAL; RAT; STRUCTURE ACTIVITY RELATION; SYMPATHETIC NERVE; AMINO ACID SEQUENCE; ANIMAL; BINDING COMPETITION; CELL CULTURE; CELL MEMBRANE; CELL STRAIN COS1; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; DOSE RESPONSE; FLUORESCENCE MICROSCOPY; KINETICS; METABOLISM; MOLECULAR GENETICS; PEPTIDE SYNTHESIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SMOOTH MUSCLE; TIME; VAS DEFERENS; WISTAR RAT;

ANIMALIA; CONUS TULIPA; GASTROPODA; TULIPA;

ALANINE; ALLOSTERIC SITE; AMINO ACID SEQUENCE; ANIMALS; ARGININE; BINDING SITES; BINDING, COMPETITIVE; CELL MEMBRANE; CELLS, CULTURED; CONOTOXINS; COS CELLS; CYSTINE; DOSE-RESPONSE RELATIONSHIP, DRUG; KINETICS; MALE; MICROSCOPY, FLUORESCENCE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH; PEPTIDE BIOSYNTHESIS; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, WISTAR; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; VAS DEFERENS;

EID: 0141817957     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305410200     Document Type: Article

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