Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist α-conotoxin OmIA that discriminates α3 vs. α6 nAChR subtypes

Biochemical and Biophysical Research Communications

Volumn 345, Issue 1, 2006, Pages 248-254

  Chi, Seung Wook ^a   Kim, Do Hyoung ^a   Olivera, Baldomero M ^b   McIntosh, J Michael ^b,c   Han, Kyou Hoon ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b UNIVERSITY OF UTAH   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Conotoxin; Nicotinic acetylcholine receptor; NMR; Peptide; Solution structure

Indexed keywords

ALPHA CONOTOXIN OMIA; ASPARAGINE; HISTIDINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3; NICOTINIC RECEPTOR ALPHA6; NICOTINIC RECEPTOR BLOCKING AGENT; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; HYDROPHILICITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; THREE DIMENSIONAL IMAGING;

BINDING SITES; CONOTOXINS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; NEURONS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; SOLUTIONS;

CONUS OMARIA;

EID: 33646431474     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.04.099     Document Type: Article

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