Amino acid residues that confer high selectivity of the α6 nicotinic acetylcholine receptor subunit to α-conotoxin MII[S4A,E11A,L15A]

Journal of Biological Chemistry

Volumn 283, Issue 17, 2008, Pages 11625-11632

  Azam, Layla ^a   Yoshikami, Doju ^a   Michael McIntosh, J ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGRICULTURAL PRODUCTS; AMINATION; AMINO ACIDS; BIOCHEMISTRY; LIGANDS; ORGANIC ACIDS; TOBACCO;

AMINO ACID RESIDUES; CENTRAL NERVOUS SYSTEMS; CONOTOXINS; DIFFERENTIAL SENSITIVITIES; HIGH SELECTIVITIES; NICOTINIC ACETYLCHOLINE RECEPTORS; NICOTINIC ACETYLCHOLINE RECEPTORS (NACHRS); PARKINSON'S DISEASES; SELECTIVE BINDINGS; TERMINAL LIGANDS; THREE ORDERS OF MAGNITUDES; XENOPUS OOCYTES;

AMINES;

ALPHA 3 NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNIT; ALPHA 6 NICOTINIC ACETYLCHOLINE RECEPTOR SUBUNIT; ALPHA CONOTOXIN MII; NICOTINIC RECEPTOR; PROTEIN SUBUNIT; UNCLASSIFIED DRUG; ALPHA-CONOTOXIN MII; CONOTOXIN; NICOTINIC RECEPTOR ALPHA6; PRIMER DNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CHIMERA; CONTROLLED STUDY; LIGAND BINDING; MUTAGENESIS; NONHUMAN; OOCYTE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; XENOPUS; AMINO ACID SEQUENCE; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; IC 50; METABOLISM; MOLECULAR GENETICS; PATCH CLAMP; PROTEIN TERTIARY STRUCTURE; RAT; XENOPUS LAEVIS;

AMINO ACID SEQUENCE; ANIMALS; CONOTOXINS; DNA PRIMERS; INHIBITORY CONCENTRATION 50; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; OOCYTES; PATCH-CLAMP TECHNIQUES; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTORS, NICOTINIC; SEQUENCE HOMOLOGY, AMINO ACID; XENOPUS LAEVIS;

EID: 45549086824     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710288200     Document Type: Article

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