Chemical syntheses and biological activities of lactam analogues of α-conotoxin SI

Journal of Medicinal Chemistry

Volumn 43, Issue 25, 2000, Pages 4787-4792

  Hargittai, B ^a,c,d   Sole N A ^a,c,d   Groebe, D R ^a,b,c,d   Abramson, S N ^b   Barany, G ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c Avecia Inc   (United States)

^d ABBOTT LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONOTOXIN; CYSTEINE; DIMETHYLTUBOCURARINE CHLORIDE; DISULFIDE; GLUTAMIC ACID; LACTAM DERIVATIVE; LYSINE; NEUROMUSCULAR BLOCKING AGENT; NICOTINIC RECEPTOR; PEPTIDE; RECEPTOR SUBUNIT; SNAIL VENOM;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; COMPETITIVE INHIBITION; CYCLIZATION; DIMERIZATION; DRUG ACTIVITY; DRUG CONFORMATION; DRUG DESIGN; DRUG SYNTHESIS; ISOMER; MOUSE; NONHUMAN; OLIGOMERIZATION; RECEPTOR AFFINITY;

ANIMALS; BINDING, COMPETITIVE; CELL LINE; CONOTOXINS; LACTAMS; MICE; RADIOLIGAND ASSAY; RECEPTORS, NICOTINIC; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034649554     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm990635c     Document Type: Article

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