Identification of tyrosine sulfation in Conus pennaceus conotoxins α-PnIA and α-PnIB: Further investigation of labile sulfo- and phosphopeptides by electrospray, matrix-assisted laser desorption/ionization (MALDI) and atmospheric pressure MALDI mass spectrometry

Journal of Mass Spectrometry

Volumn 34, Issue 4, 1999, Pages 447-454

  Wolfender, Jean Luc ^a   Chu, Feixia ^a   Ball, Haydn ^b   Wolfender, Florence ^b   Fainzilber, Michael ^c   Baldwin, Michael A ^a   Burlingame, Alma L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Atmospheric pressure matrix assisted laser desorption ionization; Conotoxin; Electrospray ionization; Matrix assisted laser desorption ionization; Sulfotyrosine

Indexed keywords

ANION; CATION; CONOTOXIN; DISULFIDE; PEPTIDE; TYROSINE;

ARTICLE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LASER; MASS SPECTROMETRY; MOLLUSC; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN QUATERNARY STRUCTURE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SULFATION;

AMINO ACID SEQUENCE; ANIMALS; CONOTOXINS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLLUSK VENOMS; OLIGOPEPTIDES; TYROSINE;

EID: 0032964781     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9888(199904)34:4<447::AID-JMS801>3.0.CO;2-1     Document Type: Article

References (39)

1. R. A. Myers, L. J. Cruz, J. Rivier and B. M. Olivera, Chem. Rev. 93, 1923 (1993).
2. A. J. Kohn, J. W. Nybakken and J. J. Van Mol, Science 176, 49 (1972).
3. L. J. Cruz, in Natural Toxins - Characterization, Pharmacology and Therapeutics, edited by C. L. Ownby and G. V. Odell, p. 66. Pergamon Press, Oxford (1989).
4. T. Nakamura, Z. Yu, M. Fainzilber and A. L. Burlingame, Protein Sci. 5, 524 (1996).
5. J. M. McIntosh, B. M. Olivera, L. J. Cruz and W. R. Gray, J. Biol. Chem. 259, 14343 (1984).
6. S. Sato, H. Nakamura, Y. Ohizumi, J. Kobayashi and Y. Hirata, FEBS Lett. 155, 277 (1983).
7. B. M. Olivera, J. M. McIntosh, L. J. Cruz, F. A. Luque and W. R. Gray, Biochemistry 23, 5087 (1984).
8. E. C. Jimenez, A. G. Craig, M. Watkins, D. R. Hillyard, W. R. Gray, J. E. Rivier, L. J. Cruz and B. M. Olivera, Biochemistry 36, 989 (1997).
9. A. G. Craig, E. C. Jimenez, J. Dykert, D. B. Nielsen, J. Gulyas, J. Porter, J. E. Rivier, L. J. Cruz, B. M. Olivera and J. M. McIntosh, J. Biol. Chem. 272, 4689 (1997).
10. E. C. Jimenez, B. M. Olivera, W. R. Gray and L. J. Cruz, J. Biol. Chem. 271, 28002 (1996).
11. M. Loughnan, T. Bond, A. Atkins, J. Cuevas, D. J. Adams, N. M. Broxton, B. G. Livett, J. G. Down, A. Jones, P. F. Alewood and R. J. Lewis, J. Biol. Chem. 273, 15667 (1998).
12. W. A. Wells, Chem. Biol. 5, R235 (1998).
13. M. Fainzilber, A. Hasson, R. Oren, A. L. Burlingame, D. S. Gordon and E. Zlotkin, Biochemistry 33, 9523 (1994).
14. M. Fainzilber, T. Nakamura, A. Gaathon, J. C. Lodder, K. S. Kits, A. L. Burlingame and E. Zlotkin, Biochemistry 34, 8649 (1995).
15. A. Hasson, M. Fainzilber, E. Zlotkin and M. Spira, Eur. J. Neurosci. 7, 815 (1995).
16. E. Czerwiec, J. P. De Backer, G. Vauquelin and P. M. Vander-heyden, Neurochem. Int. 29, 669 (1996).
17. S. H. Hu, J. Gehrmann, L W. Guddat, P. F. Alewood, D. J. Craik and J. L. Martin, Structure 4, 417 (1996).
18. K. S. Kits, J. C. Lodder, R. C. van der Schors, K. W. Li, W. P. Geraerts and M. Fainzilber, J. Neurochem. 67, 2155 (1996).
19. S. H. Hu, J. Gehrmann, P. F. Alewood, D. J. Craik and J. L. Martin, Biochemistry 36, 11323 (1997).
20. B. Diallo, P. M. Vanderheyden, J. P. De Backer and G. Vauquelin, Neurochem. Int. 32, 39 (1998).
21. M. Fainzilber, T. Nakamura, J. C. Lodder, E. Zlotkin, K. S. Kits and A. L. Burlingame, Biochemistry 37, 1470 (1998).
22. H. L. Ball and P. Mascagni, Lett. Pept. Sci. 2, 49 (1995).
23. K. F. Medzihradzky, D. A. Maltby, S. C. Hall, C. A. Settineri and A. L. Burlingame, J. Am. Soc. Mass Spectrom. 5, 350 (1994).
24. J. J. Gorman, B. L. Ferguson and T. B. Nguyen, Rapid Commun. Mass Spectrom. 10, 529 (1996).
25. A. L. Burlingame and S. A. Carr, in Mass Spectrometry in the Biological Sciences, edited by A. L. Burlingame and S. A. Carr, p. 546. Humana Press, Totowa, NJ (1996).
26. E. Stimson, O. Truong, W. J. Richter, M. D. Waterfield and A. L. Burlingame, Int. J. Mass Spectrom. Ion Processes 169/170, 231 (1997).
27. K. F. Medzihradzky, G. W. Adams, A. L. Burlingame, R. H. Bateman and M. R. Green, J. Am. Soc. Mass Spectrom. 7, 1 (1996).
28. K. F. Medzihradzky, D. A. Maltby, Y. Qiu, Z. Yu, S. C. Hall, Y. Chen and A. L. Burlingame, Int. J. Mass Spectrom. Ion Processes 160, 357 (1997).
29. R. Cramer, W. J. Richter, E. Stimson and A. L. Burlingame, Anal. Chem. 70, 4939 (1998).
30. V. Laiko and A. L. Burlingame, in Abstracts of 4th International Symposium on Mass Spectrometry in the Health and Life Sciences (1998).
31. B. W. Gibson and P. Cohen, Methods Enzymol. 193, 480 (1990).
32. T. Yagami, K. Kitagawa and S. Futaki, Rapid Commun. Mass Spectrom. 9, 1335 (1995).
33. G. Talbo and P. Roepstorff, Rapid Commun. Mass Spectrom. 7, 201 (1993).
34. M. L. Vestal, in Mass Spectrometry in Biology and Medicine, edited by A. L. Burlingame, S. Carr and M. Baldwin. Humana Press, Totowa, NJ (in press).
35. M. F. Bean, R. S. Annan, R. E. Hemling, M. Mentzer, M. J. Huddleston and S. A. Carr, in Techniques in Protein Chemistry VI, edited by J. W. Crabb, p. 107. Academic Press, San Diego (1995).
36. S. A. Carr, M. J. Huddleston and R. S. Annan, Anal. Biochem. 239, 180 (1996).
37. E. Atherton, R. C. Sheppard and P. Ward, J. Chem. Soc., Perkin Trans. 1 2065 (1985).
38. W. B. Huttner, Annu. Rev. Physiol. 50, 363 (1988).
39. W. B. Huttner, Methods Enzymol. 107, 200 (1984)