Structural determinants of selective α-conotoxin binding to a nicotinic acetylcholine receptor homolog AChBP

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 10, 2006, Pages 3615-3620

  Ulens, Chris ^a   Hogg, Ronald C ^c   Celie, Patrick H ^a   Bertrand, Daniel ^c   Tsetlin, Victor ^b   Smit, August B ^d   Sixma, Titia K ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^c UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Acetylcholine binding protein; Cys loop receptor; Ligand gated ion channel; Protein structure; X ray crystallography

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINE BINDING PROTEIN; ALPHA CONOTOXIN IMI; BINDING PROTEIN; CHOLINERGIC RECEPTOR; CONOTOXIN; LIGAND; NEUROTOXIN; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

APLYSIA; ARTICLE; CRYSTAL STRUCTURE; LIGAND BINDING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RECEPTOR BINDING; STRUCTURE ANALYSIS; SYNAPTIC TRANSMISSION; TOXIN ANALYSIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; APLYSIA; BINDING SITES; BIOPHYSICS; CONOTOXINS; CRYSTALLOGRAPHY, X-RAY; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; RECEPTORS, NICOTINIC; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

APLYSIA; APLYSIA CALIFORNICA;

EID: 33644870155     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0507889103     Document Type: Article

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