-
1
-
-
33847037399
-
-
de Boer, A. G. & Gaillard, P. J. Drug Targeting to the brain. Annu. Rev. Pharmacol. Toxicol. 47, 323-355 (2007).
-
de Boer, A. G. & Gaillard, P. J. Drug Targeting to the brain. Annu. Rev. Pharmacol. Toxicol. 47, 323-355 (2007).
-
-
-
-
2
-
-
0037119577
-
Drug targeting. Breaking down barriers
-
Miller, G. Drug targeting. Breaking down barriers. Science 297, 1116-1118 (2002).
-
(2002)
Science
, vol.297
, pp. 1116-1118
-
-
Miller, G.1
-
3
-
-
1942506065
-
Gene therapy of the brain: The trans-vascular approach
-
Schlachetzki, F., Zhang, Y., Boado, R. J. & Pardridge, W. M. Gene therapy of the brain: the trans-vascular approach. Neurology 62, 1275-1281 (2004).
-
(2004)
Neurology
, vol.62
, pp. 1275-1281
-
-
Schlachetzki, F.1
Zhang, Y.2
Boado, R.J.3
Pardridge, W.M.4
-
4
-
-
0020042226
-
Is the acetylcholine receptor a rabies virus receptor?
-
Lentz, T. L., Burrage, T. G., Smith, A. L., Crick, J. & Tignor, G. H. Is the acetylcholine receptor a rabies virus receptor? Science 215, 182-184 (1982).
-
(1982)
Science
, vol.215
, pp. 182-184
-
-
Lentz, T.L.1
Burrage, T.G.2
Smith, A.L.3
Crick, J.4
Tignor, G.H.5
-
5
-
-
16244414899
-
Rabies virus receptors
-
Lafon, M. Rabies virus receptors. J. Neurovirol. 11, 82-87 (2005).
-
(2005)
J. Neurovirol
, vol.11
, pp. 82-87
-
-
Lafon, M.1
-
6
-
-
0037370498
-
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
-
Rubinson, D. A. et al. A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference. Nature Genet. 33, 401-406 (2003).
-
(2003)
Nature Genet
, vol.33
, pp. 401-406
-
-
Rubinson, D.A.1
-
7
-
-
0034781791
-
Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery
-
Mazarakis, N. D. et al. Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral delivery. Hum. Mol. Genet. 10, 2109-2121 (2001).
-
(2001)
Hum. Mol. Genet
, vol.10
, pp. 2109-2121
-
-
Mazarakis, N.D.1
-
8
-
-
33646258017
-
A single siRNA suppresses fatal encephalitis induced by two different flaviviruses
-
Kumar, P., Lee, S. K., Shankar, P. & Manjunath, N. A single siRNA suppresses fatal encephalitis induced by two different flaviviruses. PLoS Med. 3, e96 (2006).
-
(2006)
PLoS Med
, vol.3
-
-
Kumar, P.1
Lee, S.K.2
Shankar, P.3
Manjunath, N.4
-
9
-
-
0034846184
-
Neuronal nicotinic receptors: From structure to function
-
Leonard, S. & Bertrand, D. Neuronal nicotinic receptors: from structure to function. Nicotine Tob. Res. 3, 203-223 (2001).
-
(2001)
Nicotine Tob. Res
, vol.3
, pp. 203-223
-
-
Leonard, S.1
Bertrand, D.2
-
10
-
-
0025409497
-
Rabies virus binding to an acetylcholine receptor alpha-subunit peptide
-
Lentz, T. L. Rabies virus binding to an acetylcholine receptor alpha-subunit peptide. J. Mol. Recognit. 3, 82-88 (1990).
-
(1990)
J. Mol. Recognit
, vol.3
, pp. 82-88
-
-
Lentz, T.L.1
-
11
-
-
0022341805
-
Flow cytometric analysis of tetanus toxin binding to neuroblastoma cells
-
Notter, M. F. & Leary, J. F. Flow cytometric analysis of tetanus toxin binding to neuroblastoma cells. J. Cell. Physiol. 125, 476-484 (1985).
-
(1985)
J. Cell. Physiol
, vol.125
, pp. 476-484
-
-
Notter, M.F.1
Leary, J.F.2
-
12
-
-
24944523140
-
Implication of nNOS in the enlargement of AChR aggregates but not the initial aggregate formation in a novel coculture model
-
Chen, T. J., Chen, S. S., Wu, R. E., Wang, D. C. & Lin, C. H. Implication of nNOS in the enlargement of AChR aggregates but not the initial aggregate formation in a novel coculture model. Chin. J. Physiol. 48, 129-138 (2005).
-
(2005)
Chin. J. Physiol
, vol.48
, pp. 129-138
-
-
Chen, T.J.1
Chen, S.S.2
Wu, R.E.3
Wang, D.C.4
Lin, C.H.5
-
13
-
-
11844276603
-
Neuronal nicotinic receptors: From structure to pathology
-
Gotti, C. & Clementi, F. Neuronal nicotinic receptors: from structure to pathology. Prog. Neurobiol. 74, 363-396 (2004).
-
(2004)
Prog. Neurobiol
, vol.74
, pp. 363-396
-
-
Gotti, C.1
Clementi, F.2
-
14
-
-
13844298046
-
Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides
-
Gupta, B., Levchenko, T. S. & Torchilin, V. P. Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. Adv. Drug Deliv. Rev. 57, 637-651 (2005).
-
(2005)
Adv. Drug Deliv. Rev
, vol.57
, pp. 637-651
-
-
Gupta, B.1
Levchenko, T.S.2
Torchilin, V.P.3
-
15
-
-
28144440865
-
Peptide-enhanced cellular internalization of proteins in neuroscience
-
Dietz, G. P. & Bahr, M. Peptide-enhanced cellular internalization of proteins in neuroscience. Brain Res. Bull. 68, 103-114 (2005).
-
(2005)
Brain Res. Bull
, vol.68
, pp. 103-114
-
-
Dietz, G.P.1
Bahr, M.2
-
16
-
-
23944483437
-
Cell-penetrating peptides: Tools for intracellular delivery of therapeutics
-
Deshayes, S., Morris, M. C., Divita, G. & Heitz, F. Cell-penetrating peptides: tools for intracellular delivery of therapeutics. Cell. Mol. Life Sci. 62, 1839-1849 (2005).
-
(2005)
Cell. Mol. Life Sci
, vol.62
, pp. 1839-1849
-
-
Deshayes, S.1
Morris, M.C.2
Divita, G.3
Heitz, F.4
-
17
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender, P. A. et al. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl Acad. Sci. USA 97, 13003-13008 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
-
18
-
-
33746863376
-
Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma
-
Kim, W. J. et al. Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma. Mol. Ther. 14, 343-350 (2006).
-
(2006)
Mol. Ther
, vol.14
, pp. 343-350
-
-
Kim, W.J.1
-
19
-
-
29244483102
-
In vivo delivery of small interfering RNA targeting brain capillary endothelial cells
-
Hino, T. et al. In vivo delivery of small interfering RNA targeting brain capillary endothelial cells. Biochem. Biophys. Res. Commun. 340, 263-267 (2006).
-
(2006)
Biochem. Biophys. Res. Commun
, vol.340
, pp. 263-267
-
-
Hino, T.1
-
20
-
-
15044354554
-
RNAi-induced gene silencing by local electroporation in targeting brain region
-
Akaneya, Y., Jiang, B. & Tsumoto, T. RNAi-induced gene silencing by local electroporation in targeting brain region. J. Neurophysiol. 93, 594-602 (2005).
-
(2005)
J. Neurophysiol
, vol.93
, pp. 594-602
-
-
Akaneya, Y.1
Jiang, B.2
Tsumoto, T.3
-
21
-
-
0037319970
-
B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus
-
Diamond, M. S., Shrestha, B., Marri, A., Mahan, D. & Engle, M. B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus. J. Virol. 77, 2578-2586 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 2578-2586
-
-
Diamond, M.S.1
Shrestha, B.2
Marri, A.3
Mahan, D.4
Engle, M.5
-
22
-
-
0033250024
-
Infections with flaviviridae
-
Neyts, J., Leyssen, P. & De Clercq, E. Infections with flaviviridae. Verh. K. Acad. Geneeskd Belg. 61, 661-697 (1999).
-
(1999)
Verh. K. Acad. Geneeskd Belg
, vol.61
, pp. 661-697
-
-
Neyts, J.1
Leyssen, P.2
De Clercq, E.3
-
23
-
-
22344454846
-
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA
-
Judge, A. D. et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nature Biotechnol. 23, 457-462 (2005).
-
(2005)
Nature Biotechnol
, vol.23
, pp. 457-462
-
-
Judge, A.D.1
-
24
-
-
33845205995
-
Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: Implications for target characterization in psychiatric and neurological disorders
-
Hoyer, D. et al. Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders. J. Recept. Signal Transduct. Res. 26, 527-547 (2006).
-
(2006)
J. Recept. Signal Transduct. Res
, vol.26
, pp. 527-547
-
-
Hoyer, D.1
-
25
-
-
10344261343
-
siRNA relieves chronic neuropathic pain
-
Dorn, G. et al. siRNA relieves chronic neuropathic pain. Nucleic Acids Res. 32, e49 (2004).
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Dorn, G.1
-
26
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek, J. et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 432, 173-178 (2004).
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
-
27
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey, D. V. et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nature Biotechnol. 23, 1002-1007 (2005).
-
(2005)
Nature Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
-
28
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
Zimmermann, T. S. et al. RNAi-mediated gene silencing in non-human primates. Nature 441, 111-114 (2006).
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmermann, T.S.1
-
29
-
-
4344646266
-
Development of ligand-targeted liposomes for cancer therapy
-
Noble, C. O. et al. Development of ligand-targeted liposomes for cancer therapy. Expert Opin. Ther. Targets 8, 335-353 (2004).
-
(2004)
Expert Opin. Ther. Targets
, vol.8
, pp. 335-353
-
-
Noble, C.O.1
-
30
-
-
2542561420
-
Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer
-
Zhang, Y. et al. Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer. Clin. Cancer Res. 10, 3667-3677 (2004).
-
(2004)
Clin. Cancer Res
, vol.10
, pp. 3667-3677
-
-
Zhang, Y.1
-
31
-
-
25444482607
-
Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma
-
Hu-Lieskovan, S., Heidel, J. D., Bartlett, D. W., Davis, M. E. & Triche, T. J. Sequence-specific knockdown of EWS-FLI1 by targeted, nonviral delivery of small interfering RNA inhibits tumor growth in a murine model of metastatic Ewing's sarcoma. Cancer Res. 65, 8984-8992 (2005).
-
(2005)
Cancer Res
, vol.65
, pp. 8984-8992
-
-
Hu-Lieskovan, S.1
Heidel, J.D.2
Bartlett, D.W.3
Davis, M.E.4
Triche, T.J.5
-
32
-
-
17144395917
-
Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA
-
Juliano, R. L. Peptide-oligonucleotide conjugates for the delivery of antisense and siRNA. Curr. Opin. Mol. Ther. 7, 132-136 (2005).
-
(2005)
Curr. Opin. Mol. Ther
, vol.7
, pp. 132-136
-
-
Juliano, R.L.1
-
33
-
-
28844454642
-
Arginine-rich cell penetrating peptides: From endosomal uptake to nuclear delivery
-
Melikov, K. & Chernomordik, L. V. Arginine-rich cell penetrating peptides: from endosomal uptake to nuclear delivery. Cell. Mol. Life Sci. 62, 2739-2749 (2005).
-
(2005)
Cell. Mol. Life Sci
, vol.62
, pp. 2739-2749
-
-
Melikov, K.1
Chernomordik, L.V.2
-
34
-
-
33749385780
-
Cell-penetrating peptides and antimicrobial peptides: How different are they?
-
Henriques, S. T., Melo, M. N. & Castanho, M. A. Cell-penetrating peptides and antimicrobial peptides: how different are they? Biochem. J. 399, 1-7 (2006).
-
(2006)
Biochem. J
, vol.399
, pp. 1-7
-
-
Henriques, S.T.1
Melo, M.N.2
Castanho, M.A.3
-
35
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
Song, E. et al. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nature Biotechnol. 23, 709-717 (2005).
-
(2005)
Nature Biotechnol
, vol.23
, pp. 709-717
-
-
Song, E.1
-
36
-
-
23944490153
-
The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice
-
Schutz, B. et al. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J. Neurosci. 25, 7805-7812 (2005).
-
(2005)
J. Neurosci
, vol.25
, pp. 7805-7812
-
-
Schutz, B.1
|