Identification of residues that confer α-conotoxin-PnIA sensitivity on the α3 subunit of neuronal nicotinic acetylcholine receptors

Journal of Pharmacology and Experimental Therapeutics

Volumn 306, Issue 2, 2003, Pages 664-670

  Everhart, Drew ^a   Reiller, Edward ^a,c   Mirzoian, Armen ^d   McIntosh, J Michael ^b   Malhotra, Arun ^d   Luetje, Charles W ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^c School of Veterinary Medicine   (United States)

^d NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ALPHA CONOTOXIN PNIA; ALPHA3 NICOTINIC RECEPTOR; BETA2 NICOTINIC RECEPTOR; BUNGAROTOXIN; CONOTOXIN; DRUG BINDING PROTEIN; DRUG RESIDUE; GLUTAMINE; ISOLEUCINE; KAPPA BUNGAROTOXIN; LEUCINE; NICOTINIC RECEPTOR; PROLINE; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CHIMERA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG MECHANISM; DRUG SENSITIVITY; IC 50; NEUROMUSCULAR SYNAPSE; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION; TOXIN ANALYSIS; XENOPUS;

ANIMALS; BUNGAROTOXINS; CONOTOXINS; MODELS, MOLECULAR; NEURONS; OOCYTES; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; XENOPUS LAEVIS;

EID: 0037622708     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.051656     Document Type: Article

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