Distribution and pharmacology of α6-containing nicotinic acetylcholine receptors analyzed with mutant mice

Journal of Neuroscience

Volumn 22, Issue 4, 2002, Pages 1208-1217

  Champtiaux, Nicolas ^a   Han, Zhi Yan ^a   Bessis, Alain ^a   Rossi, Francesco Mattia ^b   Zoli, Michele ^c   Marubio, Lisa ^d   Michael McIntosh, J ^d   Changeux, Jean Pierre ^d   De Moléculaire, Laboratoire Neurobiologie ^e   De La Scientifique, Centre National Recherche ^e  

^a INSTITUT PASTEUR   (France)

^b ECOLE NORMALE SUPÉRIEURE   (France)

^c UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF UTAH   (United States)

Author keywords

Dopaminergic system; Knock out; Nicotinic acetylcholine receptor; Visual system; conotoxinMII; 6 subunit

Indexed keywords

CHOLINERGIC RECEPTOR; EPTIFIBATIDE; NICOTINIC RECEPTOR; RECEPTOR SUBUNIT;

ADDICTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTORADIOGRAPHY; BEHAVIOR; BINDING AFFINITY; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC TRANSMISSION; GENE MUTATION; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR SENSITIVITY; RECEPTOR UPREGULATION; RETINA GANGLION CELL; STRIATE CORTEX; TISSUE DISTRIBUTION; VISUAL SYSTEM;

EID: 0037083377     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-04-01208.2002     Document Type: Article

References (46)

1. Mice lacking specific nicotinic acetylcholine receptor subunits exhibit dramatically altered spontaneous activity patterns and reveal a limited role for retinal waves in forming ON and OFF circuits in the inner retina
2. Disruption of dopaminergic neurotransmission in nucleus accumbens core inhibits the locomotor stimulant effects of nicotine and D-amphetamine in rats
3. A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors
4. Nicotinic acetylcholine subunit mRNA expression in dopaminergic neurons of the rat substantia nigra and ventral tegmental area
5. Self-administered nicotine activates the mesolimbic dopamine system through the ventral tegmental area
6. Role of dopamine in the behavioural actions of nicotine related to addiction
7. α-conotoxin MII (α-CTXMII) interacts with two distinct binding sites in mouse brain. Neuronal nicotinic receptors
8. Nicotinic receptor-mediated regulation of dopamine transporter activity in rat prefrontal cortex
9. Requirement for cholinergic synaptic transmission in the propagation of spontaneous retinal waves
10. Immunohistochemical localization of the nicotinic acetylcholine receptor subunit alpha6 to dopaminergic neurons in the substantia nigra and ventral tegmental area
11. Nicotinic effects on the firing pattern of midbrain dopamine neurons
12. Determinants of specificity for alpha-conotoxin MII on alpha3beta2 neuronal nicotinic receptors
13. Effect of nicotine use and withdrawal on brain preproenkephalin A mRNA
14. A PCR-based method for high stringency screening of DNA libraries
15. Differential inhibition by alpha-conotoxin-MII of the nicotinic stimulation of [3H]dopamine release from rat striatal synaptosomes and slices
16. Preparation of animals with a high degree of chimerism by one-step coculture of embryonic stem cells and preimplantation embryos
17. Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei
18. Nonpermissiveness for mouse embryonic stem (ES) cell derivation circumvented by a single backcross to 129/Sv strain: Establishment of ES cell lines bearing the Omd conditional lethal mutation
19. Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes
20. Human alpha6 AChR subtypes: Subunit composition, assembly, and pharmacological responses
21. Molecular evolution of the nicotinic acetylcholine receptor: An example of multigene family in excitable cells
22. Neuronal nicotinic receptor alpha 6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain
23. Involvement of alpha6 nicotinic receptor subunit in nicotine-elicited locomotion, demonstrated by in vivo antisense oligonucleotide infusion
24. Diversity and distribution of nicotinic acetylcholine receptors in the locus ceruleus neurons
25. Differential agonist inhibition identifies multiple epibatidine binding sites in mouse brain
26. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area
27. Hypothalamic neuropeptide Y and galanin in overweight rats fed a cafeteria diet
28. Competition in retinogeniculate patterning driven by spontaneous activity
29. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine
30. Nicotine activates and desensitizes midbrain dopamine neurons
31. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs
32. Alpha3beta4 subunit-containing nicotinic receptors dominate function in rat medial habenula neurons
33. Phenotypic characterization of an alpha 4 neuronal nicotinic acetylcholine receptor subunit knock-out mouse
34. Requirement of the nicotinic acetylcholine receptor beta 2 subunit for the anatomical and functional development of the visual system
35. The diversity of neuronal nicotinic acetylcholine receptors
36. UB-165: A novel nicotinic agonist with subtype selectivity implicates the α4β2* subtype in the modulation of dopamine release from rat striatal synaptosomes
37. Effects of chronic and subchronic nicotine on tyrosine hydroxylase activity in noradrenergic and dopaminergic neurones in the rat brain
38. Functional alpha6-containing nicotinic receptors are present in chick retina
39. 1251-alpha-conotoxin MII identifies a novel nicotinic acetylcholine receptor population in mouse brain
40. Dopamine D1 receptor and dopamine D2 receptor binding activity changes during chronic administration of nicotine in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice
41. Morphometric evaluation of populations of neuronal profiles (cell bodies, dendrites, and nerve terminals) in the central nervous system
42. Neurochemical alterations but not nerve cell loss in aged rat neostriatum
43. Developmental regulation of nicotinic ACh receptor subunit mRNAs in the rat central and peripheral nervous systems
44. Identification of four classes of brain nicotinic receptors using beta2 mutant mice