Single-residue alteration in α-conotoxin PnIA switches its nAChR subtype selectivity

Biochemistry

Volumn 38, Issue 44, 1999, Pages 14542-14548

  Luo, S ^a   Nguyen, T A ^a   Cartier, G E ^a   Olivera, B M ^a   Yoshikami, D ^a   McIntosh, J M ^a,b  

^a UNIVERSITY OF UTAH   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR; CONOTOXIN;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOLECULAR RECOGNITION; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; XENOPUS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; BINDING, COMPETITIVE; BRAIN; CHOLINERGIC ANTAGONISTS; CONOTOXINS; FEMALE; KINETICS; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLLUSK VENOMS; MUTAGENESIS, SITE-DIRECTED; OLIGOPEPTIDES; OOCYTES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CHOLINERGIC; THERMODYNAMICS; XENOPUS;

ANIMALIA; CONUS PENNACEUS; MAMMALIA;

EID: 0033517843     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi991252j     Document Type: Article

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