Structure-activity relationships in a peptidic α7 nicotinic acetylcholine receptor antagonist

Journal of Molecular Biology

Volumn 304, Issue 5, 2000, Pages 911-926

  Rogers, Jessica P ^a,b   Luginbühl, Peter ^a,d   Pemberton, Karen ^c   Harty, Patrick ^c   Wemmer, David E ^a   Stevens, Raymond C ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c Cognetix Inc ^*  (United States)

^d ETH ZURICH   (Switzerland)

Author keywords

Competitive antagonist; Neuronal nicotinic acetylcholine receptor; NMR solution structure; Peptide toxin; conotoxin ImI

Indexed keywords

CONOTOXIN; MUTANT PROTEIN; NICOTINIC RECEPTOR BLOCKING AGENT;

ARTICLE; COMPETITIVE INHIBITION; CONTROLLED STUDY; CORRELATION FUNCTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; TOXIN ANALYSIS; TOXIN STRUCTURE;

EID: 0034671348     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4247     Document Type: Article

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