Reversible sequential-binding probe receptor-ligand interactions in single cells

ChemBioChem

Volumn 6, Issue 12, 2005, Pages 2187-2194

  Schreiter, Christoph ^a   Gjoni, Marinela ^a   Hovius, Ruud ^a   Martinez, Karen L ^a   Segura, Jean Manuel ^a   Vogel, Horst ^a  

^a EPFL   (Switzerland)

Author keywords

Binding assays; Fluorescent probes; Ion channels; Nicotinic acetylcholine receptor; Single molecule studies

Indexed keywords

MEMBRANE RECEPTOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; TUBOCURARINE CHLORIDE; CELL SURFACE RECEPTOR; CONOTOXIN; FLUORESCENT DYE; LIGAND;

ACCURACY; ARTICLE; CONTROLLED STUDY; DISSOCIATION; ELECTRONICS; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; KINETICS; LIGAND BINDING; MICROFLUIDIC ANALYSIS; MOLECULAR PROBE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN STRUCTURE; SCREENING TEST; BINDING COMPETITION; CHEMISTRY; PROTEIN BINDING;

BINDING, COMPETITIVE; CONOTOXINS; FLUORESCENT DYES; KINETICS; LIGANDS; MINIATURIZATION; NICOTINIC ANTAGONISTS; PROTEIN BINDING; RECEPTORS, CELL SURFACE; RECEPTORS, NICOTINIC; TUBOCURARINE;

EID: 33745296428     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200500216     Document Type: Article

References (27)

1. J. L. Galzi, J.-P. Changeux, Neuropharmacology 1995, 34, 563-582.
2. C. Ellis, Nat. Rev. Drug Discovery 2004, 3, 577-626.
3. R. Hovius, P. Valloton, T. Wohnland, H. Vogel, Trends Pharmacol. Sci. 2000, 21, 266-273;
4. S. A. Sundberg, Curr. Opin. Biotechnol. 2000, 11, 47-53;
5. L. Zemanova, A. Schenk, M. J. Valler, G. U. Nienhaus, R. Heilker, Drug Discovery Today 2003, 8, 1085-1093.
6. H. Jankevics, M. Primmer, P. Izewska, H. Pick, K. Leufgen, H. Vogel, Biochemistry 2005, 44, 11 676-11 683.
7. P.-J. Corringer, N. Le Novere, J.-P. Changeux, Annu. Rev. Pharmacol. Toxicol. 2000, 40, 431-458.
8. A. Karlin, Nat. Rev. Neurosci. 2002, 3, 102-114.
9. G. Waksman, J.-P. Changeux, B. P. Roques, Mol. Pharmacol. 1980, 18, 20-27.
10. H. W. Meyers, R. Jurss, H. R. Brenner, G. Fels, H. Prinz, H. Watzke, A. Maelicke, Eur. J. Biochem. 1983, 137, 399-404.
11. K. L. Martinez, P.-J. Corringer, S. J. Edelstein, J.-P. Changeux, Biochemistry 2000, 39, 6979-6990.
12. K. R. Rogers, M. E. Eldefrawi, D. E. Menking, R. G. Thompson, J. J. Valdes, Biosens. Bioelectron. 1991, 6, 507-516.
13. J. D. Ashcom, B. G. Stiles, Biochem. J. 1997, 328, 245-250.
14. L. Nelson, Nature 2004, 429, 798-799.
15. V. I. Tsetlin, F. Hucho, FEBS Lett. 2004, 557, 9-13.
16. H. R. Arias, M. P. Blanton, Int. J. Biochem. Cell Biol. 2000, 32, 1017-1028.
17. A. Nicke, S. Wonnacott, R. J. Lewis, Eur. J. Biochem. 2004, 271, 2305-2319.
18. W. R. Gray, A. Luque, B. M. Olivers, J. Barrett, L. J. Cruz, J. Biol. Chem. 1981, 256, 4734-4740.
19. P. A. Quiram, S. M. Sine, J. Biol. Chem. 1998, 273, 11 007- 11 011.
20. P. Blount, J. P. Merlie, Neuron 1989, 3, 349-357.
21. M. Bäumle, D. Stamou, J. M. Segura, R. Hovius, H. Vogel, Langmuir 2004, 20, 3828-3831.
22. S. Weiss, Science 1999, 283, 1676-1683.
23. X. S. Xie, J. K. Trautman, Annu. Rev. Phys. Chem. 1998, 49, 441-480.
24. C. Schreiter, PhD thesis No. 3195, École Polytechnique Fédérale de Lausanne (Switzerland), 2005.
25. J. L. Eiselé, S. Bertrand, J. L. Galzi, A. Devillersthiery, J.-P. Changeux, D. Bertrand, Nature 1993, 366, 479-483.
26. P.-J. Corringer, J. L. Galzi, J. L. Eisele, S. Bertrand, J.-P. Changeux, D. Bertrand, J. Biol. Chem. 1995, 270, 11 749-11 752.
27. A. G. Engel, K. Ohno, S. M. Sine, Nat Rev. Neurosci. 2003, 4, 339-352.