-
1
-
-
0042035602
-
Human neurodegenerative disease modeling using Drosophila
-
DOI 10.1146/annurev.neuro.26.041002.131425
-
Bonini NM, Fortini ME. 2003. Human neurodegenerative disease modeling using Drosophila. Annu. Rev. Neurosci. 26:627-656 (Pubitemid 37064946)
-
(2003)
Annual Review of Neuroscience
, vol.26
, pp. 627-656
-
-
Bonini, N.M.1
Fortini, M.E.2
-
2
-
-
0036514504
-
Modelling neurodegenerative diseases in Drosophila: A fruitful approach?
-
Muqit MM, Feany MB. 2002. Modelling neurodegenerative diseases in Drosophila: a fruitful approach? Nat. Rev. Neurosci. 3:237-243
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 237-243
-
-
Muqit, M.M.1
Feany, M.B.2
-
3
-
-
0037373633
-
Dying for a cause: Invertebrate genetics takes on human neurodegeneration
-
DOI 10.1038/nrg1018
-
Driscoll M, Gerstbrein B. 2003. Dying for a cause: invertebrate genetics takes on human neurodegeneration. Nat. Rev. Genet. 4:181-194 (Pubitemid 36267889)
-
(2003)
Nature Reviews Genetics
, vol.4
, Issue.3
, pp. 181-194
-
-
Driscoll, M.1
Gerstbrein, B.2
-
5
-
-
0030864464
-
The Swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila
-
Kretzschmar D, Hasan G, Sharma S, Heisenberg M, Benzer S. 1997. The swisscheese mutant causes glial hyperwrapping and brain degeneration in Drosophila. J. Neurosci. 17:7425-7432 (Pubitemid 27413273)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.19
, pp. 7425-7432
-
-
Kretzschmar, D.1
Hasan, G.2
Sharma, S.3
Heisenberg, M.4
Benzer, S.5
-
6
-
-
1842687240
-
Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration
-
DOI 10.1073/pnas.0401030101
-
Akassoglou K, Malester B, Xu J, Tessarollo L, Rosenbluth J, Chao MV. 2004. Brain-specific deletion of neuropathy target esterase/swisscheese results in neurodegeneration. Proc. Natl. Acad. Sci. USA101:5075-5080 (Pubitemid 38469205)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.14
, pp. 5075-5080
-
-
Akassoglou, K.1
Malester, B.2
Xu, J.3
Tessarollo, L.4
Rosenbluth, J.5
Chao, M.V.6
-
7
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany MB, Bender WW. 2000. A Drosophila model of Parkinson's disease. Nature 404:394-398
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
8
-
-
0034597833
-
Identification of genes that modify ataxin-1-induced neurodegeneration
-
DOI 10.1038/35040584
-
Fernandez-Funez P, Nino-Rosales ML, de Gouyon B, She WC, Luchak JM, et al. 2000. Identification of genes that modify ataxin-1-induced neurodegeneration. Nature 408:101-106 (Pubitemid 30828268)
-
(2000)
Nature
, vol.408
, Issue.6808
, pp. 101-106
-
-
Fernandez-Funez, P.1
Nino-Rosales, M.L.2
De Gouyon, B.3
She, W.-C.4
Luchak, J.M.5
Martinez, P.6
Turiegano, E.7
Benito, J.8
Capovilla, M.9
Skinner, P.J.10
McCall, A.11
Canal, I.12
Orr, H.T.13
Zoghbi, H.Y.14
Botas, J.15
-
9
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
DOI 10.1073/pnas.0737556100
-
Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ. 2003. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc. Natl. Acad. Sci. USA 100:4078-4083 (Pubitemid 36418160)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
10
-
-
2542560342
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
-
DOI 10.1242/dev.01095
-
Pesah Y, Pham T, Burgess H, Middlebrooks B, Verstreken P, et al. 2004. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 131:2183-2194 (Pubitemid 38702049)
-
(2004)
Development
, vol.131
, Issue.9
, pp. 2183-2194
-
-
Pesah, Y.1
Pham, T.2
Burgess, H.3
Middlebrooks, B.4
Verstreken, P.5
Zhou, Y.6
Harding, M.7
Bellen, H.8
Mardon, G.9
-
11
-
-
0037468831
-
Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila
-
DOI 10.1016/S0896-6273(03)00143-0
-
Yang Y, Nishimura I, Imai Y, Takahashi R, Lu B. 2003. Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila. Neuron 37:911-924 (Pubitemid 36398298)
-
(2003)
Neuron
, vol.37
, Issue.6
, pp. 911-924
-
-
Yang, Y.1
Nishimura, I.2
Imai, Y.3
Takahashi, R.4
Lu, B.5
-
12
-
-
0034674713
-
Gene targeting by homologous recombination in Drosophila
-
Rong YS, Golic KG. 2000. Gene targeting by homologous recombination in Drosophila. Science 288:2013-2018
-
(2000)
Science
, vol.288
, pp. 2013-2018
-
-
Rong, Y.S.1
Golic, K.G.2
-
13
-
-
10044292870
-
Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster
-
DOI 10.1523/JNEUROSCI.2993-04.2004
-
Coulom H, Birman S. 2004. Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster. J. Neurosci. 24:10993-10998 (Pubitemid 39602410)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.48
, pp. 10993-10998
-
-
Coulom, H.1
Birman, S.2
-
15
-
-
0037431082
-
Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-Secretase complex
-
DOI 10.1016/S0896-6273(03)00205-8
-
DeStrooper B. 2003. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-secretase complex. Neuron 38:9-12 (Pubitemid 36423348)
-
(2003)
Neuron
, vol.38
, Issue.1
, pp. 9-12
-
-
De Strooper, B.1
-
16
-
-
0033615580
-
The presenilins in Alzheimer's disease - Proteolysis holds the key
-
DOI 10.1126/science.286.5441.916
-
Haass C, De Strooper B. 1999. The presenilins in Alzheimer's disease - proteolysis holds the key. Science 286:916-919 (Pubitemid 33594023)
-
(1999)
Science
, vol.286
, Issue.5441
, pp. 916-919
-
-
Haass, C.1
De Strooper, B.2
-
17
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
DOI 10.1038/ng1943, PII NG1943
-
Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, et al. 2007. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat. Genet. 39:168-177 (Pubitemid 46184347)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
Gu, Y.4
Kawarai, T.5
Zou, F.6
Katayama, T.7
Baldwin, C.T.8
Cheng, R.9
Hasegawa, H.10
Chen, F.11
Shibata, N.12
Lunetta, K.L.13
Pardossi-Piquard, R.14
Bohm, C.15
Wakutani, Y.16
Cupples, L.A.17
Cuenco, K.T.18
Green, R.C.19
Pinessi, L.20
Rainero, I.21
Sorbi, S.22
Bruni, A.23
Duara, R.24
Friedland, R.P.25
Inzelberg, R.26
Hampe, W.27
Bujo, H.28
Song, Y.-Q.29
Andersen, O.M.30
Willnow, T.E.31
Graff-Radford, N.32
Petersen, R.C.33
Dickson, D.34
Der, S.D.35
Fraser, P.E.36
Schmitt-Ulms, G.37
Younkin, S.38
Mayeux, R.39
Farrer, L.A.40
St George-Hyslop, P.41
more..
-
18
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
DOI 10.1126/science.1072994
-
Hardy J, Selkoe DJ. 2002. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297:353-356 (Pubitemid 34790756)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
19
-
-
0017649032
-
Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin
-
Cleveland DW, Hwo SY, Kirschner MW. 1977. Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin. J. Mol. Biol. 116:207-225
-
(1977)
J. Mol. Biol.
, vol.116
, pp. 207-225
-
-
Cleveland, D.W.1
Hwo, S.Y.2
Kirschner, M.W.3
-
20
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI. 1986. Abnormal phosphorylation of the microtubule-associated protein tau (Tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA 83:4913-4917 (Pubitemid 16075509)
-
(1986)
Proceedings of the National Academy of Sciences of the United States of America
, vol.83
, Issue.13
, pp. 44913-44917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.-C.3
-
21
-
-
0025292866
-
A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis
-
DOI 10.1073/pnas.87.15.5827
-
Greenberg SG, Davies P. 1990. A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis. Proc. Natl. Acad. Sci. USA 87:5827-5831 (Pubitemid 20240381)
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, Issue.15
, pp. 5827-5831
-
-
Greenberg, S.G.1
Davies, P.2
-
22
-
-
0025904444
-
A68: A major subunit of paired helical filaments and derivatized forms of normal Tau
-
Lee VM, Balin BJ, Otvos L Jr, Trojanowski JQ. 1991. A68: a major subunit of paired helical filaments and derivatized forms of normal Tau. Science 251:675-678
-
(1991)
Science
, vol.251
, pp. 675-678
-
-
Lee, V.M.1
Balin, B.J.2
Otvos Jr., L.3
Trojanowski, J.Q.4
-
23
-
-
0030977392
-
Frontotemporal dementia and parkinsonism linked to chromosome 17: A consensus conference
-
DOI 10.1002/ana.410410606
-
Foster NL, Wilhelmsen K, Sima AA, Jones MZ, D'Amato CJ, Gilman S. 1997. Frontotemporal dementia and parkinsonism linked to chromosome 17: a consensus conference. Ann. Neurol. 41:706-715 (Pubitemid 27249175)
-
(1997)
Annals of Neurology
, vol.41
, Issue.6
, pp. 706-715
-
-
Foster, N.L.1
Wilhelmsen, K.2
Sima, A.A.F.3
Jones, M.Z.4
D'Amato, C.J.5
Gilman, S.6
-
24
-
-
0032543684
-
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
-
DOI 10.1038/31508
-
Hutton M, Lendon CL, Rizzu P, Baker M, Froelich S, et al. 1998. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 393:702-705 (Pubitemid 28289662)
-
(1998)
Nature
, vol.393
, Issue.6686
, pp. 702-704
-
-
Hutton, M.1
Lendon, C.L.2
Rizzu, P.3
Baker, M.4
Froelich, S.5
Houlden, H.H.6
Pickering-Brown, S.7
Chakraverty, S.8
Isaacs, A.9
Grover, A.10
Hackett, J.11
Adamson, J.12
Lincoln, S.13
Dickson, D.14
Davies, P.15
Petersen, R.C.16
Stevena, M.17
De Graaff, E.18
Wauters, E.19
Van Baren, J.20
Hillebrand, M.21
Joosse, M.22
Kwon, J.M.23
Nowotny, P.24
Che, L.K.25
Norton, J.26
Morris, J.C.27
Reed, L.A.28
Trojanowski, J.29
Basun, H.30
Lannfelt, L.31
Neystat, M.32
Fahn, S.33
Dark, F.34
Tannenberg, T.35
Dodd, P.R.36
Hayward, N.37
Kwok, J.B.J.38
Schofield, P.R.39
Andreadis, A.40
Snowden, J.41
Craufurd, D.42
Neary, D.43
Owen, F.44
Costra, B.A.45
Hardy, J.46
Goate, A.47
Van Swieten, J.48
Mann, D.49
Lynch, T.50
Heutink, P.51
more..
-
25
-
-
14444284106
-
Tau is a candidate gene for chromosome 17 frontotemporal dementia
-
DOI 10.1002/ana.410430617
-
Poorkaj P, Bird TD, Wijsman E, Nemens E, Garruto RM, et al. 1998. Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann. Neurol. 43:815-825 (Pubitemid 28280226)
-
(1998)
Annals of Neurology
, vol.43
, Issue.6
, pp. 815-825
-
-
Poorkaj, P.1
Bird, T.D.2
Wijsman, E.3
Nemens, E.4
Garruto, R.M.5
Anderson, L.6
Andreadis, A.7
Wiederholt, W.C.8
Raskind, M.9
Schellenberg, G.D.10
-
26
-
-
0032560487
-
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
-
DOI 10.1073/pnas.95.13.7737
-
Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, Ghetti B. 1998. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proc. Natl. Acad. Sci. USA 95:7737-7741 (Pubitemid 28293323)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.13
, pp. 7737-7741
-
-
Spillantini, M.G.1
Murrell, J.R.2
Goedert, M.3
Farlow, M.R.4
Klug, A.5
Ghetti, B.6
-
27
-
-
0025863618
-
Neuropathological stageing of Alzheimer-related changes
-
Braak H, Braak E. 1991. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. (Berl.) 82:239-259
-
(1991)
Acta Neuropathol. (Berl.)
, vol.82
, pp. 239-259
-
-
Braak, H.1
Braak, E.2
-
29
-
-
0034509448
-
A very incomplete comprehensive theory of Alzheimer's disease
-
Davies P. 2000. A very incomplete comprehensive theory of Alzheimer's disease. Ann. N. Y. Acad. Sci. 924:8-16 (Pubitemid 32050176)
-
(2000)
Annals of the New York Academy of Sciences
, vol.924
, pp. 8-16
-
-
Davies, P.1
-
30
-
-
0033230886
-
Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform
-
Ishihara T, Hong M, Zhang B, Nakagawa Y, Lee MK, et al. 1999. Age-dependent emergence and progression of a tauopathy in transgenic mice overexpressing the shortest human tau isoform. Neuron 24:751-762
-
(1999)
Neuron
, vol.24
, pp. 751-762
-
-
Ishihara, T.1
Hong, M.2
Zhang, B.3
Nakagawa, Y.4
Lee, M.K.5
-
31
-
-
0034426011
-
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L)tau protein
-
DOI 10.1038/78078
-
Lewis J, McGowan E, Rockwood J, Melrose H, Nacharaju P, et al. 2000. Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein. Nat. Genet. 25:402-405 (Pubitemid 32983430)
-
(2000)
Nature Genetics
, vol.25
, Issue.4
, pp. 402-405
-
-
Lewis, J.1
McGowan, E.2
Rockwood, J.3
Melrose, H.4
Nacharaju, P.5
Van Slegtenhorst, M.6
Gwinn-Hardy, K.7
Murphy, M.P.8
Baker, M.9
Yu, X.10
Duff, K.11
Hardy, J.12
Corral, A.13
Lin, W.-L.14
Yen, S.-H.15
Dickson, D.W.16
Davies, P.17
Hutton, M.18
-
32
-
-
17944382037
-
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
-
DOI 10.1126/science.1058189
-
Lewis J, Dickson DW, Lin WL, Chisholm L, Corral A, et al. 2001. Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP. Science 293:1487-1491 (Pubitemid 32801551)
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1487-1491
-
-
Lewis, J.1
Dickson, D.W.2
Lin, W.-L.3
Chisholm, L.4
Corral, A.5
Jones, G.6
Yen, S.-H.7
Sahara, N.8
Skipper, L.9
Yager, D.10
Eckman, C.11
Hardy, J.12
Hutton, M.13
McGowan, E.14
-
33
-
-
0035943436
-
Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ42 fibrils
-
DOI 10.1126/science.1062097
-
Gotz J, Chen F, van Dorpe J, Nitsch RM. 2001. Formation of neurofibrillary tangles in P301L tau transgenic mice induced by Aβ 42 fibrils. Science 293:1491-1495 (Pubitemid 32807681)
-
(2001)
Science
, vol.293
, Issue.5534
, pp. 1491-1495
-
-
Gotz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
34
-
-
0042697305
-
Triple-transgenic model of Alzheimer's Disease with plaques and tangles: Intracellular Aβ and synaptic dysfunction
-
DOI 10.1016/S0896-6273(03)00434-3
-
Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, et al. 2003. Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Aβ and synaptic dysfunction. Neuron 39:409-421 (Pubitemid 36937044)
-
(2003)
Neuron
, vol.39
, Issue.3
, pp. 409-421
-
-
Oddo, S.1
Caccamo, A.2
Shepherd, J.D.3
Murphy, M.P.4
Golde, T.E.5
Kayed, R.6
Metherate, R.7
Mattson, M.P.8
Akbari, Y.9
Laferla, F.M.10
-
35
-
-
4043167747
-
Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
-
DOI 10.1016/j.neuron.2004.07.003, PII S0896627304004246
-
Oddo S, Billings L, Kesslak JP, Cribbs DH, LaFerla FM. 2004. Aβ immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome. Neuron 43:321-332 (Pubitemid 39061125)
-
(2004)
Neuron
, vol.43
, Issue.3
, pp. 321-332
-
-
Oddo, S.1
Billings, L.2
Kesslak, J.P.3
Cribbs, D.H.4
Laferla, F.M.5
-
36
-
-
1942440928
-
Non-Alzheimer's Disease Dementias: Anatomic, Clinical, and Molecular Correlates
-
Hou CE, Carlin D, Miller BL. 2004. Non-Alzheimer's disease dementias: anatomic, clinical, and molecular correlates. Can. J. Psychiatry 49:164-171 (Pubitemid 38506494)
-
(2004)
Canadian Journal of Psychiatry
, vol.49
, Issue.3
, pp. 164-171
-
-
Hou, C.E.1
Carlin, D.2
Miller, B.L.3
-
37
-
-
0026783241
-
Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene
-
Luo L, Tully T, White K. 1992. Human amyloid precursor protein ameliorates behavioral deficit of flies deleted for Appl gene. Neuron 9:595-605
-
(1992)
Neuron
, vol.9
, pp. 595-605
-
-
Luo, L.1
Tully, T.2
White, K.3
-
38
-
-
0033535555
-
Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants
-
Ye Y, Lukinova N, Fortini ME. 1999. Neurogenic phenotypes and altered Notch processing in Drosophila Presenilin mutants. Nature 398:525-529 (Pubitemid 129523592)
-
(1999)
Nature
, vol.398
, Issue.6727
, pp. 525-529
-
-
Ye, Y.1
Lukinova, N.2
Fortini, M.E.3
-
39
-
-
0033535508
-
Presenilin is required for activity and nuclear access of Notch in Drosophila
-
Struhl G, Greenwald I. 1999. Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature 398:522-525 (Pubitemid 129523591)
-
(1999)
Nature
, vol.398
, Issue.6727
, pp. 522-525
-
-
Struhl, G.1
Greenwald, I.2
-
40
-
-
0035829720
-
Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila
-
DOI 10.1016/S0896-6273(01)00496-2
-
Gunawardena S, Goldstein LS. 2001. Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila. Neuron 32:389-401 (Pubitemid 33082041)
-
(2001)
Neuron
, vol.32
, Issue.3
, pp. 389-401
-
-
Gunawardena, S.1
Goldstein, L.S.B.2
-
41
-
-
0032506013
-
Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype
-
DOI 10.1073/pnas.95.23.13703
-
Fossgreen A, Bruckner B, Czech C, Masters CL, Beyreuther K, Paro R. 1998. Transgenic Drosophila expressing human amyloid precursor protein show γ-secretase activity and a blistered-wing phenotype. Proc. Natl. Acad. Sci. USA 95:13703-13708 (Pubitemid 28523036)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.23
, pp. 13703-13708
-
-
Fossgreen, A.1
Bruckner, B.2
Czech, C.3
Masters, C.L.4
Beyreuther, K.5
Paro, R.6
-
42
-
-
2142645114
-
Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila
-
DOI 10.1523/JNEUROSCI.0283-04.2004
-
Greeve I, Kretzschmar D, Tschape JA, Beyn A, Brellinger C, et al. 2004. Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila. J. Neurosci. 24:3899-3906 (Pubitemid 38544216)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.16
, pp. 3899-3906
-
-
Greeve, I.1
Kretzschmar, D.2
Tschape, J.-A.3
Beyn, A.4
Brellinger, C.5
Schweizer, M.6
Nitsch, R.M.7
Reifegerste, R.8
-
43
-
-
3242809725
-
A model for studying Alzheimer's Aβ42-induced toxicity in Drosophila melanogaster
-
DOI 10.1016/j.mcn.2004.03.001, PII S1044743104000521
-
Finelli A, Kelkar A, Song HJ, Yang H, Konsolaki M. 2004. A model for studying Alzheimer's Aβ42- induced toxicity in Drosophila melanogaster. Mol. Cell Neurosci. 26:365-375 (Pubitemid 38968431)
-
(2004)
Molecular and Cellular Neuroscience
, vol.26
, Issue.3
, pp. 365-375
-
-
Finelli, A.1
Kelkar, A.2
Song, H.-J.3
Yang, H.4
Konsolaki, M.5
-
44
-
-
2342473791
-
Dissecting the pathological effects of human Aβ40 and Aβ42 in Drosophila: A potential model for Alzheimer's disease
-
DOI 10.1073/pnas.0400895101
-
IijimaK, Liu HP, Chiang AS, Hearn SA, Konsolaki M, Zhong Y. 2004. Dissecting the pathological effects of human Aβ40 and Aβ42 in Drosophila: a potential model for Alzheimer's disease. Proc. Natl. Acad. Sci. USA 101:6623-6628 (Pubitemid 38586024)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6623-6628
-
-
Iijima, K.1
Liu, H.-P.2
Chiang, A.-S.3
Hearn, S.A.4
Konsolaki, M.5
Zhong, Y.6
-
45
-
-
0034716223
-
Tau and tau reporters disrupt central projections of sensory neurons in Drosophila
-
DOI 10.1002/1096-9861(20001225)428:4<630::AID-CNE4>3.0.CO;2-X
-
Williams DW, Tyrer M, Shepherd D. 2000. Tau and tau reporters disrupt central projections of sensory neurons in Drosophila. J. Comp. Neurol. 428:630-640 (Pubitemid 30842359)
-
(2000)
Journal of Comparative Neurology
, vol.428
, Issue.4
, pp. 630-640
-
-
Williams, D.W.1
Tyrer, M.2
Shepherd, D.3
-
46
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
Wittmann CW, Wszolek MF, Shulman JM, Salvaterra PM, Lewis J, et al. 2001. Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles. Science 293:711-714 (Pubitemid 32728676)
-
(2001)
Science
, vol.293
, Issue.5530
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
47
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
DOI 10.1016/S0896-6273(02)00706-7
-
Jackson GR, Wiedau-Pazos M, Sang TK, Wagle N, Brown CA, et al. 2002. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 34:509-519 (Pubitemid 34628749)
-
(2002)
Neuron
, vol.34
, Issue.4
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.-K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
48
-
-
2542590202
-
Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons
-
DOI 10.1101/lm.70804
-
Mershin A, Pavlopoulos E, Fitch O, Braden BC, Nanopoulos DV, Skoulakis EM. 2004. Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons. Learn. Mem. 11:277-287 (Pubitemid 38697893)
-
(2004)
Learning and Memory
, vol.11
, Issue.3
, pp. 277-287
-
-
Mershin, A.1
Pavlopoulos, E.2
Fitch, O.3
Braden, B.C.4
Nanopoulos, D.V.5
Skoulakis, E.M.C.6
-
50
-
-
1542358895
-
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
-
DOI 10.1016/S0092-8674(04)00170-9, PII S0092867404001709
-
Nishimura I, Yang Y, Lu B. 2004. PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila. Cell 116:671-682 (Pubitemid 38326726)
-
(2004)
Cell
, vol.116
, Issue.5
, pp. 671-682
-
-
Nishimura, I.1
Yang, Y.2
Lu, B.3
-
51
-
-
0029024475
-
Par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed
-
Guo S, Kemphues KJ. 1995. par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed. Cell 81:611-620
-
(1995)
Cell
, vol.81
, pp. 611-620
-
-
Guo, S.1
Kemphues, K.J.2
-
52
-
-
0030969575
-
MARK, a novel family of protein kinases that phosphorylate microtubule- Associated proteins and trigger microtubule disruption
-
Drewes G, Ebneth A, Preuss U, Mandelkow EM, Mandelkow E. 1997. MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption. Cell 89:297-308 (Pubitemid 27199901)
-
(1997)
Cell
, vol.89
, Issue.2
, pp. 297-308
-
-
Drewes, G.1
Ebneth, A.2
Preuss, U.3
Mandelkow, E.-M.4
Mandelkow, E.5
-
53
-
-
0031213571
-
Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity
-
Bohm H, Brinkmann V, Drab M, Henske A, Kurzchalia TV. 1997. Mammalian homologues of C. elegans PAR-1 are asymmetrically localized in epithelial cells and may influence their polarity. Curr. Biol. 7:603-606 (Pubitemid 27335656)
-
(1997)
Current Biology
, vol.7
, Issue.8
-
-
Bohm, H.1
Brinkmann, V.2
Drab, M.3
Henske, A.4
Kurzchalia, T.V.5
-
54
-
-
0036854327
-
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of neuronal polarity
-
DOI 10.1091/mbc.02-03-0046
-
Biernat J, Wu YZ, Timm T, Zheng-Fischhofer Q, Mandelkow E, et al. 2002. Protein kinase MARK/PAR- 1 is required for neurite outgrowth and establishment of neuronal polarity. Mol. Biol. Cell 13:4013-4028 (Pubitemid 35398567)
-
(2002)
Molecular Biology of the Cell
, vol.13
, Issue.11
, pp. 4013-4028
-
-
Biernat, J.1
Wu, Y.-Z.2
Timm, T.3
Zheng-Fischhofer, Q.4
Mandelkow, E.5
Meijer, L.6
Mandelkow, E.-M.7
-
55
-
-
0346361872
-
Genetic modifiers of tauopathy in Drosophila
-
Shulman JM, Feany MB. 2003. Genetic modifiers of tauopathy in Drosophila. Genetics 165:1233-1242
-
(2003)
Genetics
, vol.165
, pp. 1233-1242
-
-
Shulman, J.M.1
Feany, M.B.2
-
56
-
-
0033391428
-
Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice
-
Cummings CJ, Reinstein E, Sun Y, Antalffy B, Jiang Y, et al. 1999. Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice. Neuron 24:879-892 (Pubitemid 30017667)
-
(1999)
Neuron
, vol.24
, Issue.4
, pp. 879-892
-
-
Cummings, C.J.1
Reinstein, E.2
Yaling, S.3
Antalffy, B.4
Jiang, Y.-H.5
Ciechanover, A.6
Orr, H.T.7
Beaudet, A.L.8
Zoghbi, H.Y.9
-
57
-
-
0031741247
-
New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry
-
Hanger DP, Betts JC, Loviny TL, Blackstock WP, Anderton BH. 1998. New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry. J. Neurochem. 71:2465-2476
-
(1998)
J. Neurochem.
, vol.71
, pp. 2465-2476
-
-
Hanger, D.P.1
Betts, J.C.2
Loviny, T.L.3
Blackstock, W.P.4
Anderton, B.H.5
-
58
-
-
33846448743
-
Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor suppressor protein LKB1
-
DOI 10.1523/JNEUROSCI.5094-06.2007
-
Wang JW, Imai Y, Lu B. 2007. Activation of PAR-1 kinase and stimulation of tau phosphorylation by diverse signals require the tumor-suppressor protein LKB1. J. Neurosci. 27:574-581 (Pubitemid 46143761)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.3
, pp. 574-581
-
-
Wang, J.-W.1
Imai, Y.2
Lu, B.3
-
59
-
-
0036937699
-
Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease
-
DOI 10.1007/s004010100423
-
Augustinack JC, Schneider A, Mandelkow EM, Hyman BT. 2002. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. Acta Neuropathol. (Berl.) 103:26-35 (Pubitemid 36075309)
-
(2002)
Acta Neuropathologica
, vol.103
, Issue.1
, pp. 26-35
-
-
Augustinack, J.C.1
Schneider, A.2
Mandelkow, E.-M.3
Hyman, B.T.4
-
60
-
-
12344306018
-
Characterization of a double (amyloid precursor protein-tau) transgenic: Tau phosphorylation and aggregation
-
DOI 10.1016/j.neuroscience.2004.09.029, PII S0306452204008644
-
Perez M, Ribe E, Rubio A, Lim F, Moran MA, et al. 2005. Characterization of a double (amyloid precursor protein-tau) transgenic: tau phosphorylation and aggregation. Neuroscience 130:339-347 (Pubitemid 40125472)
-
(2005)
Neuroscience
, vol.130
, Issue.2
, pp. 339-347
-
-
Perez, M.1
Ribe, E.2
Rubio, A.3
Lim, F.4
Moran, M.A.5
Ramos, P.G.6
Ferrer, I.7
Isla, M.T.G.8
Avila, J.9
-
61
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe DJ. 2002. Alzheimer's disease is a synaptic failure. Science 298:789-791
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
62
-
-
13944274830
-
Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-like protein 2
-
DOI 10.1523/JNEUROSCI.4660-04.2005
-
Wang P, Yang G, Mosier DR, Chang P, Zaidi T, et al. 2005. Defective neuromuscular synapses in mice lacking amyloid precursor protein (APP) and APP-like protein 2. J. Neurosci. 25:1219-1225 (Pubitemid 40268964)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.5
, pp. 1219-1225
-
-
Wang, P.1
Yang, G.2
Mosier, D.R.3
Chang, P.4
Zaidi, T.5
Gong, Y.-D.6
Zhao, N.-M.7
Dominguez, B.8
Lee, K.-F.9
Gan, W.-B.10
Zheng, H.11
-
63
-
-
0034502319
-
Synaptic structure and function in transgenic APP mice
-
Ashe KH. 2000. Synaptic structure and function in transgenic APP mice. Ann. N. Y. Acad. Sci. 924:39-41
-
(2000)
Ann. N. Y. Acad. Sci.
, vol.924
, pp. 39-41
-
-
Ashe, K.H.1
-
64
-
-
34248181511
-
Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model
-
DOI 10.1126/science.1141736
-
Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, et al. 2007. Reducing endogenous tau ameliorates amyloid β-induced deficits in an Alzheimer's disease mouse model. Science 316:750-754 (Pubitemid 46717684)
-
(2007)
Science
, vol.316
, Issue.5825
, pp. 750-754
-
-
Roberson, E.D.1
Scearce-Levie, K.2
Palop, J.J.3
Yan, F.4
Cheng, I.H.5
Wu, T.6
Gerstein, H.7
Yu, G.-Q.8
Mucke, L.9
-
65
-
-
27744600579
-
Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions
-
DOI 10.1016/j.nbd.2005.05.029, PII S0969996105001622
-
Chee FC, Mudher A, Cuttle MF, Newman TA, MacKay D, et al. 2005. Over-expression of tau results in defective synaptic transmission in Drosophila neuromuscular junctions. Neurobiol. Dis. 20:918-928 (Pubitemid 41619367)
-
(2005)
Neurobiology of Disease
, vol.20
, Issue.3
, pp. 918-928
-
-
Chee, F.C.1
Mudher, A.2
Cuttle, M.F.3
Newman, T.A.4
MacKay, D.5
Lovestone, S.6
Shepherd, D.7
-
66
-
-
33846538660
-
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
-
DOI 10.1016/j.neuron.2007.01.010, PII S089662730700030X
-
Yoshiyama Y, Higuchi M, Zhang B, Huang SM, Iwata N, et al. 2007. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron 53:337-351 (Pubitemid 46161268)
-
(2007)
Neuron
, vol.53
, Issue.3
, pp. 337-351
-
-
Yoshiyama, Y.1
Higuchi, M.2
Zhang, B.3
Huang, S.-M.4
Iwata, N.5
Saido, T.6
Maeda, J.7
Suhara, T.8
Trojanowski, J.Q.9
Lee, V.M.-Y.10
-
67
-
-
33846075630
-
PAR-1 Kinase Phosphorylates Dlg and Regulates Its Postsynaptic Targeting at the Drosophila Neuromuscular Junction
-
DOI 10.1016/j.neuron.2006.12.016, PII S089662730601021X
-
Zhang Y, Guo H, Kwan H, Wang JW, Kosek J, Lu B. 2007. PAR-1 kinase phosphorylates Dlg and regulates its postsynaptic targeting at the Drosophila neuromuscular junction. Neuron 53:201-215 (Pubitemid 46074401)
-
(2007)
Neuron
, vol.53
, Issue.2
, pp. 201-215
-
-
Zhang, Y.1
Guo, H.2
Kwan, H.3
Wang, J.-W.4
Kosek, J.5
Lu, B.6
-
68
-
-
26944467176
-
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses
-
DOI 10.1016/j.nbd.2005.02.008, PII S0969996105000720
-
Almeida CG, Tampellini D, Takahashi RH, Greengard P, Lin MT, et al. 2005. β-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Neurobiol. Dis. 20:187-198 (Pubitemid 41476246)
-
(2005)
Neurobiology of Disease
, vol.20
, Issue.2
, pp. 187-198
-
-
Almeida, C.G.1
Tampellini, D.2
Takahashi, R.H.3
Greengard, P.4
Lin, M.T.5
Snyder, E.M.6
Gouras, G.K.7
-
69
-
-
7244223228
-
Snaptic changes in alzheimer's disease: Increased amyloid-β and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence
-
Gylys KH, Fein JA, Yang F, Wiley DJ, Miller CA, Cole GM. 2004. Synaptic changes in Alzheimer's disease: Increased amyloid-β and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence. Am. J. Pathol. 165:1809-1817 (Pubitemid 39435178)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.5
, pp. 1809-1817
-
-
Gylys, K.H.1
Fein, J.A.2
Yang, F.3
Wiley, D.J.4
Miller, C.A.5
Cole, G.M.6
-
70
-
-
30644475475
-
1-40 induces NMDA-Dependent Degradation of Postsynaptic Density-95 at Glutamatergic Synapses
-
DOI 10.1523/JNEUROSCI.3034-05.2005
-
Roselli F, Tirard M, Lu J, Hutzler P, Lamberti P, et al. 2005. Soluble β-amyloid 1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses. J. Neurosci. 25:11061-11070 (Pubitemid 43089551)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.48
, pp. 11061-11070
-
-
Roselli, F.1
Tirard, M.2
Lu, J.3
Hutzler, P.4
Lamberti, P.5
Livrea, P.6
Morabito, M.7
Almeida, O.F.X.8
-
71
-
-
0028091176
-
Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease
-
Dexter DT, Sian J, Rose S, Hindmarsh JG, Mann VM, et al. 1994. Indices of oxidative stress and mitochondrial function in individuals with incidental Lewy body disease. Ann. Neurol. 35:38-44 (Pubitemid 24027604)
-
(1994)
Annals of Neurology
, vol.35
, Issue.1
, pp. 38-44
-
-
Dexter, D.T.1
Sian, J.2
Rose, S.3
Hindmarsh, J.G.4
Mann, V.M.5
Cooper, J.M.6
Wells, F.R.7
Daniel, S.E.8
Lees, A.J.9
Schapira, A.H.V.10
Jenner, P.11
Marsden, C.D.12
-
72
-
-
0040368216
-
Prospects for new restorative and neuroprotective treatments in Parkinson's disease
-
Dunnett SB, Bjorklund A. 1999. Prospects for new restorative and neuroprotective treatments in Parkinson's disease. Nature 399:A32-39 (Pubitemid 129519186)
-
(1999)
Nature
, vol.399
, Issue.6738 SUPPL.
-
-
Dunnett, S.B.1
Bjorklund, A.2
-
73
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
-
Zhang Y, Dawson VL, Dawson TM. 2000. Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol. Dis. 7:240-250
-
(2000)
Neurobiol. Dis.
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
74
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
Jenner P. 2003. Oxidative stress in Parkinson's disease. Ann. Neurol. 53(Suppl. 3):S26-38
-
(2003)
Ann. Neurol.
, vol.53
, Issue.SUPPL. 3
-
-
Jenner, P.1
-
75
-
-
0035344211
-
Experimental models of Parkinson's disease
-
Beal MF. 2001. Experimental models of Parkinson's disease. Nat. Rev. Neurosci. 2:325-334
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 325-334
-
-
Beal, M.F.1
-
76
-
-
2542458419
-
Chasing genes in Alzheimer's and Parkinson's disease
-
DOI 10.1007/s00439-004-1097-7
-
Bertoli-Avella AM, Oostra BA, Heutink P. 2004. Chasing genes in Alzheimer's and Parkinson's disease. Hum. Genet. 114:413-438 (Pubitemid 38678920)
-
(2004)
Human Genetics
, vol.114
, Issue.5
, pp. 413-438
-
-
Bertoli-Avella, A.M.1
Oostra, B.A.2
Heutink, P.3
-
77
-
-
0242363670
-
Molecular Pathways of Neurodegeneration in Parkinson's Disease
-
DOI 10.1126/science.1087753
-
Dawson TM, Dawson VL. 2003. Molecular pathways of neurodegeneration in Parkinson's disease. Science 302:819-822 (Pubitemid 37339614)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
78
-
-
0030744876
-
Mutation in the α-synuclein gene identified in families with Parkinson's disease
-
DOI 10.1126/science.276.5321.2045
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, et al. 1997. Mutation in the α-Synuclein gene identified in families with Parkinson's disease. Science 276:2045-2047 (Pubitemid 27443610)
-
(1997)
Science
, vol.276
, Issue.5321
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
79
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
DOI 10.1038/33416
-
Kitada T, Asakawa S, Hattori N, Matsumine H, Yamamura Y, et al. 1998. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392:605-608 (Pubitemid 28207717)
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
80
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E, Boyer R, Auburger G, Leube B, Ulm G, et al. 1998. The ubiquitin pathway in Parkinson's disease. Nature 395:451-452
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
Leube, B.4
Ulm, G.5
-
81
-
-
0142217556
-
DJ-1 (PARK7), a novel gene for autosomal recessive, early onset parkinsonism
-
DOI 10.1007/s10072-003-0108-0
-
Bonifati V, Rizzu P, Squitieri F, Krieger E, Vanacore N, et al. 2003. DJ-1(PARK7), a novel gene for autosomal recessive, early-onset parkinsonism. Neurol. Sci. 24:159-160 (Pubitemid 37304291)
-
(2003)
Neurological Sciences
, vol.24
, Issue.3
, pp. 159-160
-
-
Bonifati, V.1
Rizzu, P.2
Squitieri, F.3
Krieger, E.4
Vanacore, N.5
Van Swieten, J.C.6
Brice, A.7
Van Duijn, C.M.8
Oostra, B.9
Meco, G.10
Heutink, P.11
-
82
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
DOI 10.1126/science.1096284
-
Valente EM, Abou-Sleiman PM, Caputo V, Muqit MM, Harvey K, et al. 2004. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304:1158-1160 (Pubitemid 38661852)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.K.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
83
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
DOI 10.1016/j.neuron.2004.11.005, PII S0896627304007202
-
Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, et al. 2004. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44:601-607 (Pubitemid 39531225)
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
more..
-
84
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
DOI 10.1016/j.neuron.2004.10.023, PII S0896627304006890
-
Paisan-Ruiz C, Jain S, Evans EW, Gilks WP, Simon J, et al. 2004. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 44:595-600 (Pubitemid 39531224)
-
(2004)
Neuron
, vol.44
, Issue.4
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
Gilks, W.P.4
Simon, J.5
Van Der Brug, M.6
De Munain, A.L.7
Aparicio, S.8
Gil, A.M.9
Khan, N.10
Johnson, J.11
Martinez, J.R.12
Nicholl, D.13
Carrera, I.M.14
Pena, A.S.15
De Silva, R.16
Lees, A.17
Marti-Masso, J.F.18
Perez-Tur, J.19
Wood, N.W.20
Singleton, A.B.21
more..
-
85
-
-
4043079949
-
Mitochondria and dopamine: New insights into recessive parkinsonism
-
DOI 10.1016/j.neuron.2004.07.012, PII S0896627304004593
-
Shen J, Cookson MR. 2004. Mitochondria and dopamine; new insights into recessive parkinsonism. Neuron 43:301-304 (Pubitemid 39061122)
-
(2004)
Neuron
, vol.43
, Issue.3
, pp. 301-304
-
-
Shen, J.1
Cookson, M.R.2
-
86
-
-
2942684871
-
The Parkinson's disease DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
DOI 10.1073/pnas.0402959101
-
Canet-Aviles RM, Wilson MA, Miller DW, Ahmad R, McLendon C, et al. 2004. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proc. Natl. Acad. Sci. USA 101:9103-9108 (Pubitemid 38781618)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.24
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
87
-
-
0035958558
-
Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway
-
DOI 10.1038/sj.onc.1204608
-
Unoki M, Nakamura Y. 2001. Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway. Oncogene 20:4457-4465 (Pubitemid 32772428)
-
(2001)
Oncogene
, vol.20
, Issue.33
, pp. 4457-4465
-
-
Unoki, M.1
Nakamura, Y.2
-
88
-
-
33746267531
-
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
-
DOI 10.1016/j.nbd.2006.04.001, PII S0969996106000714
-
Greggio E, Jain S, Kingsbury A, Bandopadhyay R, Lewis P, et al. 2006. Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol. Dis. 23:329-341 (Pubitemid 44097032)
-
(2006)
Neurobiology of Disease
, vol.23
, Issue.2
, pp. 329-341
-
-
Greggio, E.1
Jain, S.2
Kingsbury, A.3
Bandopadhyay, R.4
Lewis, P.5
Kaganovich, A.6
Van Der Brug, M.P.7
Beilina, A.8
Blackinton, J.9
Thomas, K.J.10
Ahmad, R.11
Miller, D.W.12
Kesavapany, S.13
Singleton, A.14
Lees, A.15
Harvey, R.J.16
Harvey, K.17
Cookson, M.R.18
-
89
-
-
0034681471
-
Dopaminergic loss and inclusion body formation in α-synuclein mice: Implications for neurodegenerative disorders
-
DOI 10.1126/science.287.5456.1265
-
Masliah E, Rockenstein E, Veinbergs I, Mallory M, Hashimoto M, et al. 2000. Dopaminergic loss and inclusion body formation in α-Synuclein mice: implications for neurodegenerative disorders. Science 287:1265-1269 (Pubitemid 30112148)
-
(2000)
Science
, vol.287
, Issue.5456
, pp. 1265-1269
-
-
Masliah, E.1
Rockenstein, E.2
Veinbergs, I.3
Mallory, M.4
Hashimoto, M.5
Takeda, A.6
Sagara, Y.7
Sisk, A.8
Mucke, L.9
-
90
-
-
0141891953
-
Parkin-deficient Mice Exhibit Nigrostriatal Deficits but not Loss of Dopaminergic Neurons
-
DOI 10.1074/jbc.M308947200
-
Goldberg MS, Fleming SM, Palacino JJ, Cepeda C, Lam HA, et al. 2003. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J. Biol. Chem. 278:43628-43635 (Pubitemid 37345989)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.44
, pp. 43628-43635
-
-
Goldberg, M.S.1
Fleming, S.M.2
Palacino, J.J.3
Cepeda, C.4
Lam, H.A.5
Bhatnagar, A.6
Meloni, E.G.7
Wu, N.8
Ackerson, L.C.9
Klapstein, G.J.10
Gajendiran, M.11
Roth, B.L.12
Chesselet, M.-F.13
Maidment, N.T.14
Levine, M.S.15
Shen, J.16
-
91
-
-
13844253723
-
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial parkinsonism-linked gene DJ-1
-
DOI 10.1016/j.neuron.2005.01.041
-
Goldberg MS, Pisani A, Haburcak M, Vortherms TA, Kitada T, et al. 2005. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial parkinsonism-linked gene DJ-1. Neuron 45:489-496 (Pubitemid 40249861)
-
(2005)
Neuron
, vol.45
, Issue.4
, pp. 489-496
-
-
Goldberg, M.S.1
Pisani, A.2
Haburcak, M.3
Vortherms, T.A.4
Kitada, T.5
Costa, C.6
Tong, Y.7
Martella, G.8
Tscherter, A.9
Martins, A.10
Bernardi, G.11
Roth, B.L.12
Pothos, E.N.13
Calabresi, P.14
Shen, J.15
-
92
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6- Tetrahydropyrindine (MPTP) and oxidative stress
-
DOI 10.1073/pnas.0501282102
-
Kim RH, Smith PD, Aleyasin H, Hayley S, Mount MP, et al. 2005. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6- tetrahydropyrindine (MPTP) and oxidative stress. Proc. Natl. Acad. Sci. USA 102:5215-5220 (Pubitemid 40503765)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.14
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
Wakeham, A.7
You-Ten, A.J.8
Kalia, S.K.9
Horne, P.10
Westaway, D.11
Lozano, A.M.12
Anisman, H.13
Park, D.S.14
Mak, T.W.15
-
93
-
-
0037173006
-
Human α-synuclein-harboring familial Parkinson's disease-linked Ala-53/Thr mutation causes neurodegenerative disease with α-synuclein aggregation in transgenic mice
-
DOI 10.1073/pnas.132197599
-
Lee MK, Stirling W, Xu Y, Xu X, Qui D, et al. 2002. Human α-Synuclein-harboring familial Parkinson's disease-linked Ala-53/Thr mutation causes neurodegenerative disease with α-Synuclein aggregation in transgenic mice. Proc. Natl. Acad. Sci. USA 99:8968-8973 (Pubitemid 34693667)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.13
, pp. 8968-8973
-
-
Lee, M.K.1
Stirling, W.2
Xu, Y.3
Xu, E.4
Qui, D.5
Mandir, A.S.6
Dawson, T.M.7
Copeland, N.G.8
Jenkins, N.A.9
Price, D.L.10
-
94
-
-
0037118259
-
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
-
DOI 10.1016/S0896-6273(02)00682-7
-
Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM. 2002. Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-Synuclein. Neuron 34:521-533 (Pubitemid 34628750)
-
(2002)
Neuron
, vol.34
, Issue.4
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.-Y.6
-
95
-
-
3242677684
-
Loss of locus coeruleus neurons and reduced startle in parkin null mice
-
DOI 10.1073/pnas.0401297101
-
Von Coelln R, Thomas B, Savitt JM, Lim KL, Sasaki M, et al. 2004. Loss of locus coeruleus neurons and reduced startle in parkin null mice. Proc. Natl. Acad. Sci. USA 101:10744-10749 (Pubitemid 38955813)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.29
, pp. 10744-10749
-
-
Von Coelln, R.1
Thomas, B.2
Savitt, J.M.3
Lim, K.L.4
Sasaki, M.5
Hess, E.J.6
Dawson, V.L.7
Dawson, T.M.8
-
96
-
-
34547489872
-
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice
-
DOI 10.1073/pnas.0702717104
-
Kitada T, Pisani A, Porter DR, Yamaguchi H, Tscherter A, et al. 2007. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proc. Natl. Acad. Sci. USA 104:11441-11446 (Pubitemid 47175159)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.27
, pp. 11441-11446
-
-
Kitada, T.1
Pisani, A.2
Porter, D.R.3
Yamaguchi, H.4
Tscherter, A.5
Martella, G.6
Bonsi, P.7
Zhang, C.8
Pothos, E.N.9
Shen, J.10
-
97
-
-
0036468432
-
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
-
DOI 10.1126/science.1067389
-
Auluck PK, Chan HY, Trojanowski JQ, Lee VM, Bonini NM. 2002. Chaperone suppression of α-Synuclein toxicity in a Drosophila model for Parkinson's disease. Science 295:865-868 (Pubitemid 34118369)
-
(2002)
Science
, vol.295
, Issue.5556
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.E.2
Trojanowski, J.Q.3
Lee, V.M.-Y.4
Bonini, N.M.5
-
98
-
-
0242300619
-
α-Synuclein Locus Triplication Causes Parkinson's Disease
-
DOI 10.1126/science.1090278
-
Singleton AB, Farrer M, Johnson J, Singleton A, Hague S, et al. 2003. α-Synuclein locus triplication causes Parkinson's disease. Science 302:841 (Pubitemid 37339619)
-
(2003)
Science
, vol.302
, Issue.5646
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
99
-
-
18544362489
-
Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of α-Synuclein in Drosophila
-
DOI 10.1002/gene.20106
-
Pesah Y, Burgess H, Middlebrooks B, Ronningen K, Prosser J, et al. 2005. Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of α-Synuclein in Drosophila. Genesis 41:154-159 (Pubitemid 40656685)
-
(2005)
Genesis
, vol.41
, Issue.4
, pp. 154-159
-
-
Pesah, Y.1
Burgess, H.2
Middlebrooks, B.3
Ronningen, K.4
Prosser, J.5
Tirunagaru, V.6
Zysk, J.7
Mardon, G.8
-
100
-
-
22544458436
-
Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila
-
DOI 10.1073/pnas.0500346102
-
Cha GH, Kim S, Park J, Lee E, Kim M, et al. 2005. Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc. Natl. Acad. Sci. USA 102:10345-10350 (Pubitemid 41023373)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.29
, pp. 10345-10350
-
-
Cha, G.-H.1
Kim, S.2
Park, J.3
Lee, E.4
Kim, M.5
Lee, S.B.6
Kim, J.M.7
Chung, J.8
Cho, K.S.9
-
101
-
-
20344369560
-
Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
-
DOI 10.1073/pnas.0501078102
-
Whitworth AJ, Theodore DA, Greene JC, Benes H, Wes PD, Pallanck LJ. 2005. Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 102:8024-8029 (Pubitemid 40781056)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.22
, pp. 8024-8029
-
-
Whitworth, A.J.1
Theodore, D.A.2
Greene, J.C.3
Benes, H.4
Wes, P.D.5
Pallanck, L.J.6
-
102
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
DOI 10.1016/S0092-8674(01)00407-X
-
Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R. 2001. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105:891-902 (Pubitemid 32635090)
-
(2001)
Cell
, vol.105
, Issue.7
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, R.6
-
103
-
-
33846511271
-
Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation
-
DOI 10.1093/hmg/ddl439
-
Kitao Y, Imai Y, Ozawa K, Kataoka A, Ikeda T, et al. 2007. Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum. Mol. Genet. 16:50-60 (Pubitemid 46152544)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.1
, pp. 50-60
-
-
Kitao, Y.1
Imai, Y.2
Ozawa, K.3
Kataoka, A.4
Ikeda, T.5
Soda, M.6
Nakimawa, K.7
Kiyama, H.8
Stern, D.M.9
Hori, O.10
Wakamatsu, K.11
Ito, S.12
Itohara, S.13
Takahashi, R.14
Ogawa, S.15
-
104
-
-
24044472010
-
Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
-
DOI 10.1016/j.cub.2005.07.064, PII S0960982205008481
-
Meulener M, Whitworth AJ, Armstrong-Gold CE, Rizzu P, Heutink P, et al. 2005. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr. Biol. 15:1572-1577 (Pubitemid 41219597)
-
(2005)
Current Biology
, vol.15
, Issue.17
, pp. 1572-1577
-
-
Meulener, M.1
Whitworth, A.J.2
Armstrong-Gold, C.E.3
Rizzu, P.4
Heutink, P.5
Wes, P.D.6
Pallanck, L.J.7
Bonini, N.M.8
-
105
-
-
24044506249
-
Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress
-
Menzies FM, Yenisetti SC, Min KT. 2005. Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress. Curr. Biol. 15:1578-1582
-
(2005)
Curr. Biol.
, vol.15
, pp. 1578-1582
-
-
Menzies, F.M.1
Yenisetti, S.C.2
Min, K.T.3
-
106
-
-
26444489693
-
Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
-
DOI 10.1073/pnas.0504610102
-
Yang Y, Gehrke S, Haque ME, Imai Y, Kosek J, et al. 2005. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl. Acad. Sci. USA 102:13670-13675 (Pubitemid 41420906)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13670-13675
-
-
Yang, Y.1
Gehrke, S.2
Haque, Md.E.3
Imai, Y.4
Kosek, J.5
Yang, L.6
Beal, M.F.7
Nishimura, I.8
Wakamatsu, K.9
Ito, S.10
Takahashi, R.11
Lu, B.12
-
107
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
DOI 10.1038/nature04779, PII N04779
-
Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, et al. 2006. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 441:1162-1166 (Pubitemid 43990738)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
108
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
DOI 10.1038/nature04788, PII N04788
-
Park J, Lee SB, Lee S, Kim Y, Song S, et al. 2006. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 441:1157-1161 (Pubitemid 43990737)
-
(2006)
Nature
, vol.441
, Issue.7097
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.-M.10
Chung, J.11
-
109
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
DOI 10.1073/pnas.0602493103
-
Yang Y, Gehrke S, Imai Y, Huang Z, Ouyang Y, et al. 2006. Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proc. Natl. Acad. Sci. USA 103:10793-10798 (Pubitemid 44078055)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.28
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.-W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
-
110
-
-
33748600694
-
Antioxidants protect PINK1-dependent dopaminergic neurons in Drosophila
-
DOI 10.1073/pnas.0604661103
-
Wang D, Qian L, Xiong H, Liu J, Neckameyer WS, et al. 2006. Antioxidants protect PINK1- dependent dopaminergic neurons in Drosophila. Proc. Natl. Acad. Sci. USA 103:13520-13525 (Pubitemid 44380140)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.36
, pp. 13520-13525
-
-
Wang, D.1
Qian, L.2
Xiong, H.3
Liu, J.4
Neckameyer, W.S.5
Oldham, S.6
Xia, K.7
Wang, J.8
Bodmer, R.9
Zhang, Z.10
-
111
-
-
1142287448
-
Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease
-
DOI 10.1007/s00439-003-1050-1
-
Wu YR, Wang CK, Chen CM, Hsu Y, Lin SJ, et al. 2004. Analysis of heat-shock protein 70 gene polymorphisms and the risk of Parkinson's disease. Hum. Genet. 114:236-241 (Pubitemid 38208300)
-
(2004)
Human Genetics
, vol.114
, Issue.3
, pp. 236-241
-
-
Wu, Y.-R.1
Wang, C.-K.2
Chen, C.-M.3
Hsu, Y.4
Lin, S.-J.5
Lin, Y.-Y.6
Fung, H.-C.7
Chang, K.-H.8
Lee-Chen, G.-J.9
-
112
-
-
10944241135
-
Hsp70 gene transfer by adeno-associated virusi inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease
-
DOI 10.1016/j.ymthe.2004.09.007, PII S1525001604014480
-
Dong Z, Wolfer DP, Lipp HP, Bueler H. 2005. Hsp70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease. Mol. Ther. 11:80-88 (Pubitemid 40012001)
-
(2005)
Molecular Therapy
, vol.11
, Issue.1
, pp. 80-88
-
-
Dong, Z.1
Wolfer, D.P.2
Lipp, H.-P.3
Bueler, H.4
-
113
-
-
0036174010
-
α-Synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, et al. 2002. α-Synuclein is phosphorylated in synucleinopathy lesions. Nat. Cell Biol. 4:160-164
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
-
114
-
-
17844406856
-
α-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease
-
DOI 10.1038/nn1443
-
Chen L, Feany MB. 2005. α-Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease. Nat. Neurosci. 8:657-663 (Pubitemid 40594208)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.5
, pp. 657-663
-
-
Chen, L.1
Feany, M.B.2
-
115
-
-
0035854437
-
Ubiquitination of a new form of α-synuclein by parkin from human brain: Implications for Parkinson's disease
-
DOI 10.1126/science.1060627
-
Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, et al. 2001. Ubiquitination of a new form of α-Synuclein by parkin from human brain: implications for Parkinson's disease. Science 293:263-269 (Pubitemid 32694735)
-
(2001)
Science
, vol.293
, Issue.5528
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
116
-
-
2642516493
-
Parkin counteracts symptoms in a Drosophila model of Parkinson's disease
-
Haywood AF, Staveley BE. 2004. Parkin counteracts symptoms in a Drosophila model of Parkinson's disease. BMC Neurosci. 5:14
-
(2004)
BMC Neurosci.
, vol.5
, pp. 14
-
-
Haywood, A.F.1
Staveley, B.E.2
-
117
-
-
0037137702
-
Parkin protects against the toxicity associated with mutant α-Synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons
-
DOI 10.1016/S0896-6273(02)01125-X
-
Petrucelli L, O'Farrell C, Lockhart PJ, Baptista M, Kehoe K, et al. 2002. Parkin protects against the toxicity associated with mutant α-Synuclein: Proteasome dysfunction selectively affects catecholaminergic neurons. Neuron 36:1007-1019 (Pubitemid 36044504)
-
(2002)
Neuron
, vol.36
, Issue.6
, pp. 1007-1019
-
-
Petrucelli, L.1
O'Farrell, C.2
Lockhart, P.J.3
Baptista, M.4
Kehoe, K.5
Vink, L.6
Choi, P.7
Wolozin, B.8
Farrer, M.9
Hardy, J.10
Cookson, M.R.11
-
118
-
-
10644281090
-
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-synuclein rat model of Parkinson's disease
-
DOI 10.1073/pnas.0405313101
-
Lo Bianco C, Schneider BL, Bauer M, Sajadi A, Brice A, et al. 2004. Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an α-Synuclein rat model of Parkinson's disease. Proc. Natl. Acad. Sci. USA 101:17510-17515 (Pubitemid 39657434)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.50
, pp. 17510-17515
-
-
Lo Bianco, C.1
Schneider, B.L.2
Bauer, M.3
Sajadi, A.4
Brice, A.5
Iwatsubo, T.6
Aebischer, P.7
-
119
-
-
20244365801
-
DJ-1, a novel regulator of the tumor suppressor PTEN
-
DOI 10.1016/j.ccr.2005.02.010
-
Kim RH, Peters M, Jang Y, Shi W, Pintilie M, et al. 2005. DJ-1, a novel regulator of the tumor suppressor PTEN. Cancer Cell 7:263-273 (Pubitemid 40568685)
-
(2005)
Cancer Cell
, vol.7
, Issue.3
, pp. 263-273
-
-
Kim, R.H.1
Peters, M.2
Jang, Y.3
Shi, W.4
Pintilie, M.5
Fletcher, G.C.6
Deluca, C.7
Liepa, J.8
Zhou, L.9
Snow, B.10
Binari, R.C.11
Manoukian, A.S.12
Bray, M.R.13
Liu, F.-F.14
Tsao, M.-S.15
Mak, T.W.16
-
120
-
-
0021811271
-
Low cancer rates among patients with Parkinson's disease
-
DOI 10.1002/ana.410170514
-
Jansson B, Jankovic J. 1985. Low cancer rates among patients with Parkinson's disease. Ann. Neurol. 17:505-509 (Pubitemid 15019991)
-
(1985)
Annals of Neurology
, vol.17
, Issue.5
, pp. 505-509
-
-
Jansson, B.1
Jankovic, J.2
-
121
-
-
33745274726
-
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
-
DOI 10.1016/j.cell.2006.06.010, PII S0092867406007689
-
Chan DC. 2006. Mitochondria: dynamic organelles in disease, aging, and development. Cell 125:1241-1252 (Pubitemid 43929096)
-
(2006)
Cell
, vol.125
, Issue.7
, pp. 1241-1252
-
-
Chan, D.C.1
-
122
-
-
10944269186
-
The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses
-
DOI 10.1016/j.cell.2004.11.003, PII S0092867404010451
-
Li Z, Okamoto K, Hayashi Y, Sheng M. 2004. The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses. Cell 119:873-887 (Pubitemid 40017692)
-
(2004)
Cell
, vol.119
, Issue.6
, pp. 873-887
-
-
Li, Z.1
Okamoto, K.-I.2
Hayashi, Y.3
Sheng, M.4
-
123
-
-
0344413426
-
Mitochondrial fission in apoptosis, neurodegeneration and aging
-
DOI 10.1016/j.ceb.2003.10.015
-
Bossy-Wetzel E, Barsoum MJ, Godzik A, Schwarzenbacher R, Lipton SA. 2003. Mitochondrial fission in apoptosis, neurodegeneration and aging. Curr. Opin. Cell Biol. 15:706-716 (Pubitemid 37487964)
-
(2003)
Current Opinion in Cell Biology
, vol.15
, Issue.6
, pp. 706-716
-
-
Bossy-Wetzel, E.1
Barsoum, M.J.2
Godzik, A.3
Schwarzenbacher, R.4
Lipton, S.A.5
-
124
-
-
0038051345
-
Mitochondria, oxidative damage, and inflammation in Parkinson's disease
-
Beal MF. 2003. Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann. N. Y. Acad. Sci. 991:120-131 (Pubitemid 36793808)
-
(2003)
Annals of the New York Academy of Sciences
, vol.991
, pp. 120-131
-
-
Beal, M.F.1
-
125
-
-
0017187807
-
Biochemical adaptations for flight in the insect
-
Sacktor B. 1976. Biochemical adaptations for flight in the insect. Biochem. Soc. Symp. 41:111-131
-
(1976)
Biochem. Soc. Symp.
, vol.41
, pp. 111-131
-
-
Sacktor, B.1
-
126
-
-
0141841634
-
Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease
-
DOI 10.1093/hmg/ddg265
-
Scherzer CR, Jensen RV, Gullans SR, Feany MB. 2003. Gene expression changes presage neurodegeneration in a Drosophila model of Parkinson's disease. Hum. Mol. Genet. 12:2457-2466 (Pubitemid 37220410)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.19
, pp. 2457-2466
-
-
Scherzer, C.R.1
Jensen, R.V.2
Gullans, S.R.3
Feany, M.B.4
-
127
-
-
5744248243
-
Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases
-
DOI 10.1093/hmg/ddh214
-
Ghosh S, Feany MB. 2004. Comparison of pathways controlling toxicity in the eye and brain in Drosophila models of human neurodegenerative diseases. Hum. Mol. Genet. 13:2011-2018 (Pubitemid 39377825)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.18
, pp. 2011-2018
-
-
Ghosh, S.1
Feany, M.B.2
-
128
-
-
0034329159
-
Molecular genetics: Unmasking polyglutamine triggers in neurodegenerative disease
-
Gusella JF, MacDonald ME. 2000. Molecular genetics: unmasking polyglutamine triggers in neurodegenerative disease. Nat. Rev. Neurosci. 1:109-115
-
(2000)
Nat. Rev. Neurosci.
, vol.1
, pp. 109-115
-
-
Gusella, J.F.1
MacDonald, M.E.2
-
129
-
-
0034110465
-
Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila
-
Marsh JL, Walker H, Theisen H, Zhu YZ, Fielder T, et al. 2000. Expanded polyglutamine peptides alone are intrinsically cytotoxic and cause neurodegeneration in Drosophila. Hum. Mol. Genet. 9:13-25 (Pubitemid 30145284)
-
(2000)
Human Molecular Genetics
, vol.9
, Issue.1
, pp. 13-25
-
-
Marsh, J.L.1
Walker, H.2
Theisen, H.3
Zhu, Y.-Z.4
Fielder, T.5
Purcell, J.6
Thompson, L.M.7
-
130
-
-
0037194896
-
Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila
-
Takeyama K, Ito S, Yamamoto A, Tanimoto H, Furutani T, et al. 2002. Androgen-dependent neurodegeneration by polyglutamine-expanded human androgen receptor in Drosophila. Neuron 35:855-864
-
(2002)
Neuron
, vol.35
, pp. 855-864
-
-
Takeyama, K.1
Ito, S.2
Yamamoto, A.3
Tanimoto, H.4
Furutani, T.5
-
131
-
-
0037726598
-
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1
-
DOI 10.1016/S0092-8674(03)00349-0
-
Chen HK, Fernandez-Funez P, Acevedo SF, Lam YC, Kaytor MD, et al. 2003. Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell 113:457-468 (Pubitemid 36588749)
-
(2003)
Cell
, vol.113
, Issue.4
, pp. 457-468
-
-
Chen, H.-K.1
Fernandez-Funez, P.2
Acevedo, S.F.3
Lam, Y.C.4
Kaytor, M.D.5
Fernandez, M.H.6
Aitken, A.7
Skoulakis, E.M.C.8
Orr, H.T.9
Botas, J.10
Zoghbi, H.Y.11
-
132
-
-
0037846441
-
Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice
-
Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, et al. 2003. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice. Neuron 38:375-387
-
(2003)
Neuron
, vol.38
, pp. 375-387
-
-
Emamian, E.S.1
Kaytor, M.D.2
Duvick, L.A.3
Zu, T.4
Tousey, S.K.5
-
133
-
-
23944438950
-
The AXH domain of ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/senseless proteins
-
DOI 10.1016/j.cell.2005.06.012, PII S0092867405005957
-
Tsuda H, Jafar-Nejad H, Patel AJ, Sun Y, Chen HK, et al. 2005. The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Cell 122:633-644 (Pubitemid 41191160)
-
(2005)
Cell
, vol.122
, Issue.4
, pp. 633-644
-
-
Tsuda, H.1
Jafar-Nejad, H.2
Patel, A.J.3
Sun, Y.4
Chen, H.-K.5
Rose, M.F.6
Venken, K.J.T.7
Botas, J.8
Orr, H.T.9
Bellen, H.J.10
Zoghbi, H.Y.11
-
134
-
-
0036850456
-
Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila
-
Chan HY, Warrick JM, Andriola I, Merry D, Bonini NM. 2002. Genetic modulation of polyglutamine toxicity by protein conjugation pathways in Drosophila. Hum. Mol. Genet. 11:2895-2904
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 2895-2904
-
-
Chan, H.Y.1
Warrick, J.M.2
Andriola, I.3
Merry, D.4
Bonini, N.M.5
-
135
-
-
11144353613
-
SUMO Modification of Huntingtin and Huntington's Disease Pathology
-
DOI 10.1126/science.1092194
-
Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, et al. 2004. SUMO modification of Huntingtin and Huntington's disease pathology. Science 304:100-104 (Pubitemid 38451465)
-
(2004)
Science
, vol.304
, Issue.5667
, pp. 100-104
-
-
Steffan, J.S.1
Agrawal, N.2
Pallos, J.3
Rockabrand, E.4
Trotman, L.C.5
Slepko, N.6
Illes, K.7
Lukacsovich, T.8
Zhu, Y.-Z.9
Cattaneo, E.10
Pandolfi, P.P.11
Thompson, L.M.12
Marsh, J.L.13
-
136
-
-
0032168160
-
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons
-
DOI 10.1016/S0896-6273(00)80573-5
-
Jackson GR, Salecker I, Dong X, Yao X, Arnheim N, et al. 1998. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron 21:633-642 (Pubitemid 28475514)
-
(1998)
Neuron
, vol.21
, Issue.3
, pp. 633-642
-
-
Jackson, G.R.1
Salecker, I.2
Dong, X.3
Yao, X.4
Arnheim, N.5
Faber, P.W.6
MacDonald, M.E.7
Zipursky, S.L.8
-
137
-
-
13644260686
-
Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis
-
DOI 10.1093/hmg/ddi032
-
Sang TK, Li C, Liu W, Rodriguez A, Abrams JM, et al. 2005. Inactivation of Drosophila Apaf-1-related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. Hum. Mol. Genet. 14:357-372 (Pubitemid 40227371)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.3
, pp. 357-372
-
-
Sang, T.-K.1
Li, C.2
Liu, W.3
Rodriguez, A.4
Abrams, J.M.5
Zipursky, S.L.6
Jackson, G.R.7
-
138
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
DOI 10.1016/S0896-6273(03)00594-4
-
Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, et al. 2003. Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 40:25-40 (Pubitemid 37222462)
-
(2003)
Neuron
, vol.40
, Issue.1
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.-S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.B.9
-
140
-
-
10744224530
-
Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport
-
DOI 10.1016/S0896-6273(03)00569-5
-
Szebenyi G, Morfini GA, Babcock A, Gould M, Selkoe K, et al. 2003. Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport. Neuron 40:41-52 (Pubitemid 37229083)
-
(2003)
Neuron
, vol.40
, Issue.1
, pp. 41-52
-
-
Szebenyi, G.1
Morfini, G.A.2
Babcock, A.3
Gould, M.4
Selkoe, K.5
Stenoien, D.L.6
Young, M.7
Faber, P.W.8
MacDonald, M.E.9
McPhaul, M.J.10
Brady, S.T.11
-
141
-
-
0041880131
-
RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila
-
DOI 10.1016/S0896-6273(03)00533-6
-
Jin P, Zarnescu DC, Zhang F, Pearson CE, Lucchesi JC, et al. 2003. RNA-mediated neurodegeneration caused by the fragile X premutation rCGG repeats in Drosophila. Neuron 39:739-747 (Pubitemid 37088087)
-
(2003)
Neuron
, vol.39
, Issue.5
, pp. 739-747
-
-
Jin, P.1
Zarnescu, D.C.2
Zhang, F.3
Pearson, C.E.4
Lucchesi, J.C.5
Moses, K.6
Warren, S.T.7
-
142
-
-
1542380523
-
The Spinocerebellar Ataxia 8 noncoding RNA causes neurodegeneration and associates with Staufen in Drosophila
-
DOI 10.1016/S0960-9822(04)00048-X, PII S096098220400048X
-
Mutsuddi M, Marshall CM, Benzow KA, Koob MD, Rebay I. 2004. The spinocerebellar ataxia 8 noncoding RNA causes neurodegeneration and associates with staufen in Drosophila. Curr. Biol. 14:302-308 (Pubitemid 38300207)
-
(2004)
Current Biology
, vol.14
, Issue.4
, pp. 302-308
-
-
Mutsuddi, M.1
Marshall, C.M.2
Benzow, K.A.3
Koob, M.D.4
Rebay, I.5
-
143
-
-
15544387787
-
Myotonic dystrophy associated expanded CUG repeat muscleblind positive ribonuclear foci are not toxic to Drosophila
-
DOI 10.1093/hmg/ddi080
-
Houseley JM, Wang Z, Brock GJ, Soloway J, Artero R, et al. 2005. Myotonic dystrophy associated expanded CUG repeat muscleblind positive ribonuclear foci are not toxic to Drosophila. Hum. Mol. Genet. 14:873-883 (Pubitemid 40403282)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.6
, pp. 873-883
-
-
Houseley, J.M.1
Wang, Z.2
Brock, G.J.R.3
Soloway, J.4
Artero, R.5
Perez-Alonso, M.6
O'Dell, K.M.C.7
Monckton, D.G.8
-
144
-
-
33845234260
-
Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Straussler-Scheinker syndrome
-
DOI 10.1523/JNEUROSCI.3372-06.2006
-
Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, et al. 2006. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Straussler- Scheinker syndrome. J. Neurosci. 26:12408-12414 (Pubitemid 44864505)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.48
, pp. 12408-12414
-
-
Gavin, B.A.1
Dolph, M.J.2
Deleault, N.R.3
Geoghegan, J.C.4
Khurana, V.5
Feany, M.B.6
Dolph, P.J.7
Supattapone, S.8
-
145
-
-
0033581027
-
Preventing neurodegeneration in the Drosophila mutant bubblegum
-
DOI 10.1126/science.284.5422.1985
-
Min KT, Benzer S. 1999. Preventing neurodegeneration in the Drosophila mutant bubblegum. Science 284:1985-1988 (Pubitemid 29309445)
-
(1999)
Science
, vol.284
, Issue.5422
, pp. 1985-1988
-
-
Min, K.-T.1
Benzer, S.2
-
146
-
-
0035909330
-
Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila
-
DOI 10.1038/35099568
-
Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, et al. 2001. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature 413:739-743 (Pubitemid 33009952)
-
(2001)
Nature
, vol.413
, Issue.6857
, pp. 739-743
-
-
Steffan, J.S.1
Bodai, L.2
Pallos, J.3
Poelman, M.4
McCampbell, A.5
Apostol, B.L.6
Kazantsev, A.7
Schmidt, E.8
Zhu, Y.-Z.9
Greenwald, M.10
Kurokawa, R.11
Housman, D.E.12
Jackson, G.R.13
Marsh, J.L.14
Thompson, L.M.15
-
147
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
DOI 10.1038/ng1362
-
Ravikumar B, Vacher C, Berger Z, Davies JE, Luo S, et al. 2004. Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. Nat. Genet. 36:585-595 (Pubitemid 38715985)
-
(2004)
Nature Genetics
, vol.36
, Issue.6
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
148
-
-
31544454404
-
Rapamycin alleviates toxicity of different aggregate-prone proteins
-
DOI 10.1093/hmg/ddi458
-
Berger Z, Ravikumar B, Menzies FM, Oroz LG, Underwood BR, et al. 2006. Rapamycin alleviates toxicity of different aggregate-prone proteins. Hum. Mol. Genet. 15:433-442 (Pubitemid 43159895)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.3
, pp. 433-442
-
-
Berger, Z.1
Ravikumar, B.2
Menzies, F.M.3
Oroz, L.G.4
Underwood, B.R.5
Pangalos, M.N.6
Schmitt, I.7
Wullner, U.8
Evert, B.O.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
149
-
-
0036852712
-
Pharmacological prevention of Parkinson disease in Drosophila
-
Auluck PK, Bonini NM. 2002. Pharmacological prevention of Parkinson disease in Drosophila. Nat. Med. 8:1185-1186
-
(2002)
Nat. Med.
, vol.8
, pp. 1185-1186
-
-
Auluck, P.K.1
Bonini, N.M.2
-
150
-
-
3142592230
-
GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila
-
DOI 10.1038/sj.mp.4001483
-
Mudher A, Shepherd D, Newman TA, Mildren P, Jukes JP, et al. 2004. GSK-3β inhibition reverses axonal transport defects and behavioural phenotypes in Drosophila. Mol. Psychiatry 9:522-523 (Pubitemid 38903508)
-
(2004)
Molecular Psychiatry
, vol.9
, Issue.5
, pp. 522-530
-
-
Mudher, A.1
Shepherd, D.2
Newman, T.A.3
Mildren, P.4
Jukes, J.P.5
Squire, A.6
Mears, A.7
Berg, S.8
MacKay, D.9
Asuni, A.A.10
Bhat, R.11
Lovestone, S.12
|