-
1
-
-
10544236116
-
The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine
-
Arnold C. S., Johnson G. V., Cole R. N., Dong D. Y., Lee M., and Hart G. W. (1996) The microtubule-associated protein tau is extensively modified with O-linked N-acetylglucosamine. J. Biol. Chem. 271, 28741-28744.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 28741-28744
-
-
Arnold, C.S.1
Johnson, G.V.2
Cole, R.N.3
Dong, D.Y.4
Lee, M.5
Hart, G.W.6
-
2
-
-
0028879044
-
Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: Implication of phosphoprotein phosphatase involvement
-
Baum L., Seger R., Woodgett J. R., Kawabata S., Maruyama K., Koyama M., Silver J., and Saitoh T. (1995) Overexpressed tau protein in cultured cells is phosphorylated without formation of PHF: implication of phosphoprotein phosphatase involvement. Mol. Brain Res. 34, 1-17.
-
(1995)
Mol. Brain Res.
, vol.34
, pp. 1-17
-
-
Baum, L.1
Seger, R.2
Woodgett, J.R.3
Kawabata, S.4
Maruyama, K.5
Koyama, M.6
Silver, J.7
Saitoh, T.8
-
3
-
-
0030914528
-
Identification of phosphorylation sites on neurofilament proteins by nanoelectrospray mass spectrometry
-
Betts J. C., Blackstock W. P., Ward M. A., and Anderton B. H. (1997) Identification of phosphorylation sites on neurofilament proteins by nanoelectrospray mass spectrometry. J. Biol. Chem. 272, 12922-12927.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12922-12927
-
-
Betts, J.C.1
Blackstock, W.P.2
Ward, M.A.3
Anderton, B.H.4
-
4
-
-
0027338266
-
Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding
-
Biernat J., Gustke N., Drewes G., Mandelkow E. M., and Mandelkow E. (1993) Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding. Neuron 11, 153-163.
-
(1993)
Neuron
, vol.11
, pp. 153-163
-
-
Biernat, J.1
Gustke, N.2
Drewes, G.3
Mandelkow, E.M.4
Mandelkow, E.5
-
5
-
-
0022257253
-
Mise en evidence immunologique de la proteine tau au niveau des lesions de degenerescence neurofibrillaire de la maladie d'Alzheimer
-
Brion J.-P., Passareiro H., Nunez J., and Flament-Durand J. (1985) Mise en evidence immunologique de la proteine tau au niveau des lesions de degenerescence neurofibrillaire de la maladie d'Alzheimer. Arch. Biol. (Brux.) 95, 229-235.
-
(1985)
Arch. Biol. (Brux.)
, vol.95
, pp. 229-235
-
-
Brion, J.-P.1
Passareiro, H.2
Nunez, J.3
Flament-Durand, J.4
-
6
-
-
0026097837
-
Tau in Alzheimer neurofibrillary tangles: N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site
-
Brion J.-P., Hanger D. P., Bruce M. T., Couck A. M., Flament-Durand J., and Anderton B. H. (1991a) Tau in Alzheimer neurofibrillary tangles: N-and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal phosphorylation site. Biochem. J. 273, 127-133.
-
(1991)
Biochem. J.
, vol.273
, pp. 127-133
-
-
Brion, J.-P.1
Hanger, D.P.2
Bruce, M.T.3
Couck, A.M.4
Flament-Durand, J.5
Anderton, B.H.6
-
7
-
-
0025949088
-
A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities
-
Brion J.-P., Hanger D. P., Couck A. M., and Anderton B. H. (1991b) A68 proteins in Alzheimer's disease are composed of several tau isoforms in a phosphorylated state which affects their electrophoretic mobilities. Biochem. J. 279, 831-836.
-
(1991)
Biochem. J.
, vol.279
, pp. 831-836
-
-
Brion, J.-P.1
Hanger, D.P.2
Couck, A.M.3
Anderton, B.H.4
-
8
-
-
0027429479
-
Developmental changes in τ phosphorylation: Fetal τ is transiently phosphorylated in a manner similar to paired helical filament-τ characteristic of Alzheimer's disease
-
Brion J.-P., Smith C., Couck A.-M., Gallo J.-M., and Anderton B. H. (1993) Developmental changes in τ phosphorylation: fetal τ is transiently phosphorylated in a manner similar to paired helical filament-τ characteristic of Alzheimer's disease. J. Neurochem. 61, 2071-2080.
-
(1993)
J. Neurochem.
, vol.61
, pp. 2071-2080
-
-
Brion, J.-P.1
Smith, C.2
Couck, A.-M.3
Gallo, J.-M.4
Anderton, B.H.5
-
9
-
-
0029925968
-
Site-specific regulation of Alzheimer-like tau phosphorylation in living neurons
-
Burack M. A. and Halpain S. (1996) Site-specific regulation of Alzheimer-like tau phosphorylation in living neurons. Neuroscience 72, 167-184.
-
(1996)
Neuroscience
, vol.72
, pp. 167-184
-
-
Burack, M.A.1
Halpain, S.2
-
10
-
-
0030218817
-
Selective detection and sequencing of phosphopeptides at the femtomole level by mass spectrometry
-
Carr S. A., Huddleston M. J., and Annan R. S. (1996) Selective detection and sequencing of phosphopeptides at the femtomole level by mass spectrometry. Anal. Biochem. 239, 180-192.
-
(1996)
Anal. Biochem.
, vol.239
, pp. 180-192
-
-
Carr, S.A.1
Huddleston, M.J.2
Annan, R.S.3
-
11
-
-
0032539986
-
Identification of novel in vitro PKA phosphorylation sites on the low and middle molecular mass neurofilament subunits by mass spectrometry
-
Cleverley K. E., Betts J. C., Blackstock W. P., Gallo J. M., and Anderton B. H. (1998) Identification of novel in vitro PKA phosphorylation sites on the low and middle molecular mass neurofilament subunits by mass spectrometry. Biochemistry 37, 3917-3930.
-
(1998)
Biochemistry
, vol.37
, pp. 3917-3930
-
-
Cleverley, K.E.1
Betts, J.C.2
Blackstock, W.P.3
Gallo, J.M.4
Anderton, B.H.5
-
12
-
-
0026625670
-
Microtubule-associated protein tau is phosphorylated by protein kinase C on its tubulin binding domain
-
Correas I., Diaz Nido J., and Avila J. (1992) Microtubule-associated protein tau is phosphorylated by protein kinase C on its tubulin binding domain. J. Biol. Chem. 267, 15721-15728.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15721-15728
-
-
Correas, I.1
Diaz Nido, J.2
Avila, J.3
-
13
-
-
0022185841
-
Immunological characterization of microtubule-associated proteins specific for the immature brain
-
Couchie D. and Nunez J. (1985) Immunological characterization of microtubule-associated proteins specific for the immature brain. FEBS Lett. 188, 331-335.
-
(1985)
FEBS Lett.
, vol.188
, pp. 331-335
-
-
Couchie, D.1
Nunez, J.2
-
14
-
-
0001784039
-
LC/MS and LC/MS/MS screening for the sites of post-translational modification in proteins
-
Jornall H., Hoog J. O., and Gustavsson A. M., eds, Birkhauser Press, Basel
-
Covey T., Shushan B., Bonner R., Schroder W., and Hucho F. (1991) LC/MS and LC/MS/MS screening for the sites of post-translational modification in proteins, in Methods in Protein Sequence Analysis (Jornall H., Hoog J. O., and Gustavsson A. M., eds), pp. 249-256. Birkhauser Press, Basel.
-
(1991)
Methods in Protein Sequence Analysis
, pp. 249-256
-
-
Covey, T.1
Shushan, B.2
Bonner, R.3
Schroder, W.4
Hucho, F.5
-
15
-
-
0026549985
-
Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state
-
Drewes G., Lichtenberg-Kraag B., Doring F., Mandelkow E.-M., Biernat J., Goris J., Doree M., and Mandelkow E. (1992) Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state. EMBO J. 11, 2131-2138.
-
(1992)
EMBO J.
, vol.11
, pp. 2131-2138
-
-
Drewes, G.1
Lichtenberg-Kraag, B.2
Doring, F.3
Mandelkow, E.-M.4
Biernat, J.5
Goris, J.6
Doree, M.7
Mandelkow, E.8
-
16
-
-
0027753055
-
Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A
-
Drewes G., Mandelkow E. M., Baumann K., Goris J., Merlevede W., and Mandelkow E. (1993) Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcineurin and phosphatase-2A. FEBS Lett. 336, 425-432.
-
(1993)
FEBS Lett.
, vol.336
, pp. 425-432
-
-
Drewes, G.1
Mandelkow, E.M.2
Baumann, K.3
Goris, J.4
Merlevede, W.5
Mandelkow, E.6
-
17
-
-
0028937631
-
mark). a novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262
-
mark). A novel protein kinase that regulates tau-microtubule interactions and dynamic instability by phosphorylation at the Alzheimer-specific site serine 262. J. Biol. Chem. 270, 7679-7688.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7679-7688
-
-
Drewes, G.1
Trinczek, B.2
Illenberger, S.3
Biernat, J.4
Schmitt-Ulms, G.5
Meyer, H.E.6
Mandelkow, E.-M.7
Mandelkow, E.8
-
18
-
-
0024595412
-
Direct demonstration of abnormal phosphorylation of Tau microtubular proteins in Alzheimer's disease
-
Flament S., Delacourte A., Hemon B., and Defossez A. (1989) Direct demonstration of abnormal phosphorylation of Tau microtubular proteins in Alzheimer's disease. C. R. Acad. Sci. III 308, 77-82.
-
(1989)
C. R. Acad. Sci. III
, vol.308
, pp. 77-82
-
-
Flament, S.1
Delacourte, A.2
Hemon, B.3
Defossez, A.4
-
19
-
-
0018649358
-
Spongiform alterations in brain biopsies of presenile dementia
-
Flament-Durand J. and Couck A. M. (1979) Spongiform alterations in brain biopsies of presenile dementia. Acta Neuropathol. (Berl.) 46, 159-162.
-
(1979)
Acta Neuropathol. (Berl.)
, vol.46
, pp. 159-162
-
-
Flament-Durand, J.1
Couck, A.M.2
-
20
-
-
0026786976
-
Expression and phosphorylation of a three-repeat isoform of tau in transfccted non-neuronal cells
-
Gallo J.-M., Hanger D. P., Twist E. C., Kosik K. S., and Anderton B. H. (1992) Expression and phosphorylation of a three-repeat isoform of tau in transfccted non-neuronal cells. Biochem. J. 286, 399-404.
-
(1992)
Biochem. J.
, vol.286
, pp. 399-404
-
-
Gallo, J.-M.1
Hanger, D.P.2
Twist, E.C.3
Kosik, K.S.4
Anderton, B.H.5
-
21
-
-
0028173238
-
τ phosphorylation in human, primate, and rat brain: Evidence that a pool of τ is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro
-
Garver T. D., Harris K. A., Lehman R. A. W., Lee V. M. Y., Trojanowski J. Q., and Billingsley M. L. (1994) τ phosphorylation in human, primate, and rat brain: evidence that a pool of τ is highly phosphorylated in vivo and is rapidly dephosphorylated in vitro. J. Neurochem. 63, 2279-2287.
-
(1994)
J. Neurochem.
, vol.63
, pp. 2279-2287
-
-
Garver, T.D.1
Harris, K.A.2
Lehman, R.A.W.3
Lee, V.M.Y.4
Trojanowski, J.Q.5
Billingsley, M.L.6
-
22
-
-
0024745894
-
Multiple isoforms of human microtubule-associated protein tau: Sequences and localization in neurofibrillary tangles of Alzheimer's disease
-
Goedert M., Spillantini M. G., Jakes R., Rutherford D., and Crowther R. A. (1989) Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3, 519-526.
-
(1989)
Neuron
, vol.3
, pp. 519-526
-
-
Goedert, M.1
Spillantini, M.G.2
Jakes, R.3
Rutherford, D.4
Crowther, R.A.5
-
23
-
-
0026595846
-
Tau proteins of Alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms
-
Goedert M., Spillantini M. G., Cairns N. J., and Crowther R. A. (1992) Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 8, 159-168.
-
(1992)
Neuron
, vol.8
, pp. 159-168
-
-
Goedert, M.1
Spillantini, M.G.2
Cairns, N.J.3
Crowther, R.A.4
-
24
-
-
0027984739
-
Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: Identification of phosphorylation sites in tau protein
-
Goedert M., Jakes R., Crowther R. A., Cohen P., Vanmechelen E., Vandermeeren M., and Cras P. (1994) Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein. Biochem. J. 301, 871-877.
-
(1994)
Biochem. J.
, vol.301
, pp. 871-877
-
-
Goedert, M.1
Jakes, R.2
Crowther, R.A.3
Cohen, P.4
Vanmechelen, E.5
Vandermeeren, M.6
Cras, P.7
-
25
-
-
0029907548
-
Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
-
Goedert M., Jakes R., Spillantini M. G., Hasegawa M., Smith M. J., and Crowther R. A. (1996) Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature 383, 550-553.
-
(1996)
Nature
, vol.383
, pp. 550-553
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
Hasegawa, M.4
Smith, M.J.5
Crowther, R.A.6
-
27
-
-
0025292866
-
A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis
-
Greenberg S. G. and Davies P. (1990) A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis. Proc. Natl. Acad. Sci. USA 87, 5827-5831.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 5827-5831
-
-
Greenberg, S.G.1
Davies, P.2
-
29
-
-
0022744803
-
Abnormal phosphorylation of the microtubule-associated protein τ (tau) in Alzheimer cytoskeletal pathology
-
Grundke-Iqbal I., Iqbal K., Tung Y. C., Quinlan M., Wisniewski H. M., and Binder L. I. (1986) Abnormal phosphorylation of the microtubule-associated protein τ (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad. Sci. USA 83, 4913-4917.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4913-4917
-
-
Grundke-Iqbal, I.1
Iqbal, K.2
Tung, Y.C.3
Quinlan, M.4
Wisniewski, H.M.5
Binder, L.I.6
-
30
-
-
0025893793
-
Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated
-
Hanger D. P., Brion J.-P., Gallo J.-M., Cairns N. J., Luthert P. J., and Anderton B. H. (1991) Tau in Alzheimer's disease and Down's syndrome is insoluble and abnormally phosphorylated. Biochem. J. 275, 99-104.
-
(1991)
Biochem. J.
, vol.275
, pp. 99-104
-
-
Hanger, D.P.1
Brion, J.-P.2
Gallo, J.-M.3
Cairns, N.J.4
Luthert, P.J.5
Anderton, B.H.6
-
31
-
-
0026787130
-
Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain
-
Hasegawa M., Morishima-Kawashima M., Takio K., Suzuki M., Titani K., and Ihara Y. (1992) Protein sequence and mass spectrometric analyses of tau in the Alzheimer's disease brain. J. Biol. Chem. 267, 17047-17054.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 17047-17054
-
-
Hasegawa, M.1
Morishima-Kawashima, M.2
Takio, K.3
Suzuki, M.4
Titani, K.5
Ihara, Y.6
-
32
-
-
0031439109
-
Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation
-
Hasegawa M., Crowther R. A., Jakes R., and Goedert M. (1997) Alzheimer-like changes in microtubule-associated protein Tau induced by sulfated glycosaminoglycans. Inhibition of microtubule binding, stimulation of phosphorylation, and filament assembly depend on the degree of sulfation. J. Biol. Chem. 272, 33118-33124.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 33118-33124
-
-
Hasegawa, M.1
Crowther, R.A.2
Jakes, R.3
Goedert, M.4
-
33
-
-
0030750558
-
Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites
-
Hoffmann R., Lee V. Y., Leight S., Varga I., and Otvos L. (1997) Unique Alzheimer's disease paired helical filament specific epitopes involve double phosphorylation at specific sites. Biochemistry 36, 8114-8124.
-
(1997)
Biochemistry
, vol.36
, pp. 8114-8124
-
-
Hoffmann, R.1
Lee, V.Y.2
Leight, S.3
Varga, I.4
Otvos, L.5
-
34
-
-
0024312664
-
Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease
-
Iqbal K., Grundke-Iqbal I., Smith A. J., George L., Tung Y. C., and Zaidi T. (1989) Identification and localization of a tau peptide to paired helical filaments of Alzheimer disease. Proc. Natl. Acad. Sci. USA 86, 5646-5650.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 5646-5650
-
-
Iqbal, K.1
Grundke-Iqbal, I.2
Smith, A.J.3
George, L.4
Tung, Y.C.5
Zaidi, T.6
-
35
-
-
0028361538
-
Alzheimer paired helical filaments: Restoration of the biological activity by dephosphorylation
-
Iqbal K., Zaidi T., Bancher C., and Grundke-Iqbal I. (1994) Alzheimer paired helical filaments: restoration of the biological activity by dephosphorylation. FEBS Lett. 349, 104-108.
-
(1994)
FEBS Lett.
, vol.349
, pp. 104-108
-
-
Iqbal, K.1
Zaidi, T.2
Bancher, C.3
Grundke-Iqbal, I.4
-
36
-
-
0026619472
-
Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments
-
Ishiguro K., Omori A., Takamatsu M., Sato K., Arioka M., Uchida T., and Imahori K. (1992) Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments. Neurosci. Lett. 148, 202-206.
-
(1992)
Neurosci. Lett.
, vol.148
, pp. 202-206
-
-
Ishiguro, K.1
Omori, A.2
Takamatsu, M.3
Sato, K.4
Arioka, M.5
Uchida, T.6
Imahori, K.7
-
37
-
-
0027255817
-
Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments
-
Ishiguro K., Shiratsuchi A., Sato S., Omori A., Arioka M., Kobayashi S., Uchida T., and Imahori K. (1993) Glycogen synthase kinase 3 beta is identical to tau protein kinase I generating several epitopes of paired helical filaments. FEBS Lett. 325, 167-172.
-
(1993)
FEBS Lett.
, vol.325
, pp. 167-172
-
-
Ishiguro, K.1
Shiratsuchi, A.2
Sato, S.3
Omori, A.4
Arioka, M.5
Kobayashi, S.6
Uchida, T.7
Imahori, K.8
-
38
-
-
0029618170
-
Analysis of phosphorylation of tau with antibodies specific for phosphorylation sites
-
Ishiguro K., Sato K., Takamatsu M., Park J. M., Uchida T., and Imahori K. (1995) Analysis of phosphorylation of tau with antibodies specific for phosphorylation sites. Neurosci. Lett. 202, 81-84.
-
(1995)
Neurosci. Lett.
, vol.202
, pp. 81-84
-
-
Ishiguro, K.1
Sato, K.2
Takamatsu, M.3
Park, J.M.4
Uchida, T.5
Imahori, K.6
-
39
-
-
0027372016
-
The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments
-
Kenessey A. and Yen S. H. (1993) The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments. Brain Res. 629, 40-46.
-
(1993)
Brain Res.
, vol.629
, pp. 40-46
-
-
Kenessey, A.1
Yen, S.H.2
-
40
-
-
0027361281
-
Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease
-
Kopke E., Tung Y. C., Shaikh S., Alonso A. C., Iqbal K., and Grundke-Iqbal I. (1993) Microtubule-associated protein tau. Abnormal phosphorylation of a non-paired helical filament pool in Alzheimer disease. J. Biol. Chem. 268, 24374-24384.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24374-24384
-
-
Kopke, E.1
Tung, Y.C.2
Shaikh, S.3
Alonso, A.C.4
Iqbal, K.5
Grundke-Iqbal, I.6
-
41
-
-
0009364134
-
Microtubule-associated protein tau is a major antigenic component of paired helical filaments in Alzheimer disease
-
Kosik K. S., Joachim C. L., and Selkoe D. J. (1986) Microtubule-associated protein tau is a major antigenic component of paired helical filaments in Alzheimer disease. Proc. Natl. Acad. Sci. USA 83, 4044-4048.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4044-4048
-
-
Kosik, K.S.1
Joachim, C.L.2
Selkoe, D.J.3
-
42
-
-
0025254157
-
Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties
-
Ksiezak-Reding H., Binder L. I., and Yen S. H. (1990) Alzheimer disease proteins (A68) share epitopes with tau but show distinct biochemical properties. J. Neurosci. Res. 25, 420-430.
-
(1990)
J. Neurosci. Res.
, vol.25
, pp. 420-430
-
-
Ksiezak-Reding, H.1
Binder, L.I.2
Yen, S.H.3
-
43
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli U. K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
44
-
-
0028065142
-
Analysis of microtubule-associated protein Tau glycation in paired helical filaments
-
Ledesma M. D., Bonay P., Colaço C., and Avila J. (1994) Analysis of microtubule-associated protein Tau glycation in paired helical filaments. J. Biol. Chem. 269, 21614-21619.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21614-21619
-
-
Ledesma, M.D.1
Bonay, P.2
Colaço, C.3
Avila, J.4
-
45
-
-
0025904444
-
A68: A major subunit of paired helical filaments and derivatized forms of normal tau
-
Lee V. M. Y., Balin B. J., Otvos L., and Trojanowski J. Q. (1991) A68: a major subunit of paired helical filaments and derivatized forms of normal tau. Science 251, 675-678.
-
(1991)
Science
, vol.251
, pp. 675-678
-
-
Lee, V.M.Y.1
Balin, B.J.2
Otvos, L.3
Trojanowski, J.Q.4
-
46
-
-
0029899091
-
Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356
-
Litersky J. M., Johnson G. V. W., Jakes R., Goedert M., Lee M., and Seubert P. (1996) Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356. Biochem. J. 316, 655-660.
-
(1996)
Biochem. J.
, vol.316
, pp. 655-660
-
-
Litersky, J.M.1
Johnson, G.V.W.2
Jakes, R.3
Goedert, M.4
Lee, M.5
Seubert, P.6
-
47
-
-
0028675873
-
Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells
-
Lovestone S., Reynolds C. H., Latimer D., Davis D. R., Anderton B. H., Gallo J.-M., Hanger D., Mulot S., Marquardt B., Stabel S., Woodgett J. R., and Miller C. C. J. (1994) Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells. Curr. Biol. 4, 1077-1086.
-
(1994)
Curr. Biol.
, vol.4
, pp. 1077-1086
-
-
Lovestone, S.1
Reynolds, C.H.2
Latimer, D.3
Davis, D.R.4
Anderton, B.H.5
Gallo, J.-M.6
Hanger, D.7
Mulot, S.8
Marquardt, B.9
Stabel, S.10
Woodgett, J.R.11
Miller, C.C.J.12
-
48
-
-
0027945346
-
Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau
-
Matsuo E. S., Shin R.-W., Billingsley M. L., Van DeVoorde A., O'Connor M., Trojanowski J. Q., and Lee V. M. Y. (1994) Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau. Neuron 13, 989-1002.
-
(1994)
Neuron
, vol.13
, pp. 989-1002
-
-
Matsuo, E.S.1
Shin, R.-W.2
Billingsley, M.L.3
Van DeVoorde, A.4
O'Connor, M.5
Trojanowski, J.Q.6
Lee, V.M.Y.7
-
49
-
-
0023140474
-
Ubiquitin is a component of paired helical filaments in Alzheimer's disease
-
Mori H., Kondo J., and Ihara Y. (1987) Ubiquitin is a component of paired helical filaments in Alzheimer's disease. Science 235, 1641-1644.
-
(1987)
Science
, vol.235
, pp. 1641-1644
-
-
Mori, H.1
Kondo, J.2
Ihara, Y.3
-
50
-
-
0028899714
-
Proline-directed and non-proline-directed phosphorylation of PHF-tau
-
Morishima-Kawashima M., Hasegawa M., Takio K., Suzuki M., Yoshida H., Titani K., and Ihara Y. (1995a) Proline-directed and non-proline-directed phosphorylation of PHF-tau. J. Biol. Chem. 270, 823-829.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 823-829
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Titani, K.6
Ihara, Y.7
-
51
-
-
0029010035
-
Hyperphosphorylation of tau in PHF
-
Morishima-Kawashima M., Hasegawa M., Takio K., Suzuki M., Yoshida H., Watanabe A., Titani K., and Ihara Y. (1995b) Hyperphosphorylation of tau in PHF. Neurobiol. Aging 16, 365-371.
-
(1995)
Neurobiol. Aging
, vol.16
, pp. 365-371
-
-
Morishima-Kawashima, M.1
Hasegawa, M.2
Takio, K.3
Suzuki, M.4
Yoshida, H.5
Watanabe, A.6
Titani, K.7
Ihara, Y.8
-
52
-
-
0027990436
-
PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3β
-
Mulot S. F. C., Hughes K., Woodgett J. R., Anderton B. H., and Hanger D. P. (1994) PHF-tau from Alzheimer's brain comprises four species on SDS-PAGE which can be mimicked by in vitro phosphorylation of human brain tau by glycogen synthase kinase-3β. FEBS Lett. 349, 359-364.
-
(1994)
FEBS Lett.
, vol.349
, pp. 359-364
-
-
Mulot, S.F.C.1
Hughes, K.2
Woodgett, J.R.3
Anderton, B.H.4
Hanger, D.P.5
-
53
-
-
0030614508
-
The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase
-
Paudel H. K. (1997) The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase. J. Biol. Chem. 272, 1777-1785.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 1777-1785
-
-
Paudel, H.K.1
-
54
-
-
0027508998
-
Phosphorylation of recombinant tau by cAMP-dependent protein kinase. Identification of phosphorylation sites and effect on microtubule assembly
-
Scott C. W., Spreen R. C., Herman J. L., Chow F. P., Davison M. D., Young J., and Caputo C. B. (1993) Phosphorylation of recombinant tau by cAMP-dependent protein kinase. Identification of phosphorylation sites and effect on microtubule assembly. J. Biol. Chem. 268, 1166-1173.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1166-1173
-
-
Scott, C.W.1
Spreen, R.C.2
Herman, J.L.3
Chow, F.P.4
Davison, M.D.5
Young, J.6
Caputo, C.B.7
-
55
-
-
0028803726
-
Isoelectric point differentiates PHF-tau from biopsy-derived human brain tau proteins
-
Sergeant N., Bussière T., Vermersch P., Lejeune J. P., and Delacourte A. (1995) Isoelectric point differentiates PHF-tau from biopsy-derived human brain tau proteins. Neuroreport 6, 2217-2220.
-
(1995)
Neuroreport
, vol.6
, pp. 2217-2220
-
-
Sergeant, N.1
Bussière, T.2
Vermersch, P.3
Lejeune, J.P.4
Delacourte, A.5
-
56
-
-
0030840778
-
Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: Demonstration of an additional 74-kDa component and age-related biochemical modifications
-
Sergeant N., David J.-P., Goedert M., Jakes R., Vermersch P., Buée L., Lefranc D., Wattez A., and Delacourte A. (1997) Two-dimensional characterization of paired helical filament-tau from Alzheimer's disease: demonstration of an additional 74-kDa component and age-related biochemical modifications. J. Neurochem. 69, 834-844.
-
(1997)
J. Neurochem.
, vol.69
, pp. 834-844
-
-
Sergeant, N.1
David, J.-P.2
Goedert, M.3
Jakes, R.4
Vermersch, P.5
Buée, L.6
Lefranc, D.7
Wattez, A.8
Delacourte, A.9
-
57
-
-
0028978701
-
262 in fetal tau, adult tau, and paired helical filament tau
-
262 in fetal tau, adult tau, and paired helical filament tau. J. Biol. Chem. 270, 18917-18922.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18917-18922
-
-
Seubert, P.1
Mawal-Dewan, M.2
Barbour, R.3
Jakes, R.4
Goedert, M.5
Johnson, G.V.W.6
Litersky, J.M.7
Schenk, D.8
Lieberburg, I.9
Trojanowski, J.Q.10
Lee, V.M.Y.11
-
58
-
-
0028918921
-
400 sites phosphorylated in Alzheimer disease brain
-
400 sites phosphorylated in Alzheimer disease brain. J. Protein Chem. 14, 95-106.
-
(1995)
J. Protein Chem.
, vol.14
, pp. 95-106
-
-
Song, J.-S.1
Yang, S.-D.2
-
59
-
-
0028933292
-
Involvement of τ protein kinase I in paired helical filament-like phosphorylation of the juvenile τ in rat brain
-
Takahashi M., Tomizawa K., Ishiguro K., Takamatsu M., Fujita S. C., and Imahori K. (1995) Involvement of τ protein kinase I in paired helical filament-like phosphorylation of the juvenile τ in rat brain. J. Neurochem. 64, 1759-1768.
-
(1995)
J. Neurochem.
, vol.64
, pp. 1759-1768
-
-
Takahashi, M.1
Tomizawa, K.2
Ishiguro, K.3
Takamatsu, M.4
Fujita, S.C.5
Imahori, K.6
-
60
-
-
0026521716
-
A protein kinase associated with paired helical filaments in Alzheimer disease
-
Vincent I. J. and Davies P. (1992) A protein kinase associated with paired helical filaments in Alzheimer disease. Proc. Natl. Acad. Sci. USA 89, 2878-2882.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2878-2882
-
-
Vincent, I.J.1
Davies, P.2
-
61
-
-
0026564431
-
Proline-directed phosphorylation of human tau protein
-
Vulliet R., Halloran S. M., Braun R. K., Smith A. J., and Lee G. (1992) Proline-directed phosphorylation of human tau protein. J. Biol. Chem. 267, 22570-22574.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 22570-22574
-
-
Vulliet, R.1
Halloran, S.M.2
Braun, R.K.3
Smith, A.J.4
Lee, G.5
-
62
-
-
0027370141
-
In vivo phosphorylation sites in fetal and adult rat tau
-
Watanabe A., Hasegawa M., Suzuki M., Takio K., Morishima-Kawashima M., Titani K., Arai T., Kosik K. S., and Ihara Y. (1993) In vivo phosphorylation sites in fetal and adult rat tau. J. Biol. Chem. 268, 25712-25717.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 25712-25717
-
-
Watanabe, A.1
Hasegawa, M.2
Suzuki, M.3
Takio, K.4
Morishima-Kawashima, M.5
Titani, K.6
Arai, T.7
Kosik, K.S.8
Ihara, Y.9
-
63
-
-
0000217562
-
Electrospray and taylor-cone theory, Dole's beam of macromolecules at last?
-
Wilm M. S. and Mann M. (1994) Electrospray and taylor-cone theory, Dole's beam of macromolecules at last? Int. J. Mass Spectrom. Ion Process. 136, 167-180.
-
(1994)
Int. J. Mass Spectrom. Ion Process.
, vol.136
, pp. 167-180
-
-
Wilm, M.S.1
Mann, M.2
-
64
-
-
0029685702
-
Analytical properties of the nanoelectrospray ion source
-
Wilm M. and Mann M. (1996) Analytical properties of the nanoelectrospray ion source. Anal. Chem. 68, 1-8.
-
(1996)
Anal. Chem.
, vol.68
, pp. 1-8
-
-
Wilm, M.1
Mann, M.2
-
65
-
-
0030033198
-
Parent ion scans of unseparated peptide mixtures
-
Wilm M., Neubauer G., and Mann M. (1996a) Parent ion scans of unseparated peptide mixtures. Anal. Chem. 68, 527-533.
-
(1996)
Anal. Chem.
, vol.68
, pp. 527-533
-
-
Wilm, M.1
Neubauer, G.2
Mann, M.3
-
66
-
-
0030026070
-
Femtomole sequencing of proteins from polyacrylamide gels by nanoelectrospray mass spectrometry
-
Wilm M., Shevchenko A., Houthaeve T., Breit S., Schweigerer L., Fotsis T., and Mann M. (1996b) Femtomole sequencing of proteins from polyacrylamide gels by nanoelectrospray mass spectrometry. Nature 379, 466-469.
-
(1996)
Nature
, vol.379
, pp. 466-469
-
-
Wilm, M.1
Shevchenko, A.2
Houthaeve, T.3
Breit, S.4
Schweigerer, L.5
Fotsis, T.6
Mann, M.7
-
67
-
-
0003986552
-
Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease
-
Wischik C. M., Novak M., Thogersen H. C., Edwards P. C., Runswick M. J., Jakes R., Walker J. E., Milstein C., Roth M., and Klug A. (1988) Isolation of a fragment of tau derived from the core of the paired helical filament of Alzheimer disease. Proc. Natl. Acad. Sci. USA 85, 4506-4510.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4506-4510
-
-
Wischik, C.M.1
Novak, M.2
Thogersen, H.C.3
Edwards, P.C.4
Runswick, M.J.5
Jakes, R.6
Walker, J.E.7
Milstein, C.8
Roth, M.9
Klug, A.10
-
68
-
-
0028170044
-
A/glycogen synthase kinase-3α after heparin potentiation phosphorylates τ on sites abnormally phosphorylated in Alzheimer's disease brain
-
A/glycogen synthase kinase-3α after heparin potentiation phosphorylates τ on sites abnormally phosphorylated in Alzheimer's disease brain. J. Neurochem. 63, 1416-1425.
-
(1994)
J. Neurochem.
, vol.63
, pp. 1416-1425
-
-
Yang, S.-D.1
Yu, J.-S.2
Shiah, S.-G.3
Huang, J.-J.4
-
69
-
-
0027237861
-
τ in paired helical filaments is functionally distinct from fetal τ: Assembly incompetence of paired helical filament τ
-
Yoshida H. and Ihara Y. (1993) τ in paired helical filaments is functionally distinct from fetal τ: assembly incompetence of paired helical filament τ. J. Neurochem. 61, 1183-1186.
-
(1993)
J. Neurochem.
, vol.61
, pp. 1183-1186
-
-
Yoshida, H.1
Ihara, Y.2
|