Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila

Journal of Neuroscience

Volumn 24, Issue 16, 2004, Pages 3899-3906

  Greeve, Isabell ^a,b   Kretzschmar, Doris ^c   Tschäpe, Jakob Andreas ^c   Beyn, Anika ^a,e   Brellinger, Claire ^a   Schweizer, Michaela ^a   Nitsch, Roger M ^a,d   Reifegerste, Rita ^a,e,f  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e Evotec Technologies GmbH   (Germany)

^f Evotec Neurosciences GmbH   (Germany)

Author keywords

Aging; Alzheimer; Degeneration; Dementia; Drosophila; Neuropathology

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE INHIBITOR; GAMMA SECRETASE INHIBITOR;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEMENTIA; DROSOPHILA; GENE MUTATION; NEUROLOGIC DISEASE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SENILE PLAQUE; TRANSGENIC ANIMAL;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANIMALS, GENETICALLY MODIFIED; ASPARTIC ENDOPEPTIDASES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DROSOPHILA; DROSOPHILA PROTEINS; ENDOPEPTIDASES; GENE TARGETING; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; MEMBRANE PROTEINS; MUTATION; PHENOTYPE; PHOTORECEPTORS, INVERTEBRATE; PRESENILINS; PROTEIN PROCESSING, POST-TRANSLATIONAL; RETINA; SENILE PLAQUES; SURVIVAL RATE; TRANSGENES;

EID: 2142645114     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0283-04.2004     Document Type: Review

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