-
1
-
-
0010899576
-
-
(ed. Stern, G.) Chapman & Hall, London
-
Forno, L. S. in Parkinson's Disease (ed. Stern, G.) 185-238 (Chapman & Hall, London, 1990).
-
(1990)
Parkinson's Disease
, pp. 185-238
-
-
Forno, L.S.1
-
2
-
-
0002135343
-
α-Synuclein and the Lewy body
-
Goedert, M., Jakes, R. & Spillantini, M. G. α-Synuclein and the Lewy body. Neurosci. News 1, 47-52 (1998).
-
(1998)
Neurosci. News
, vol.1
, pp. 47-52
-
-
Goedert, M.1
Jakes, R.2
Spillantini, M.G.3
-
3
-
-
0032936755
-
Etiology and pathogenesis of Parkinson's disease
-
Olanow, C. W. & Tatton, WG. Etiology and pathogenesis of Parkinson's disease. Annu. Rev. Neurosci. 22, 123-144 (1999).
-
(1999)
Annu. Rev. Neurosci.
, vol.22
, pp. 123-144
-
-
Olanow, C.W.1
Tatton, W.G.2
-
4
-
-
0031719117
-
Alzheimer's disease and Parkinson's disease; distinct entities or extremes of a spectrum of neurodegeneration?
-
Perl, D. P., Olanow, C. W. & Calne, D. B. Alzheimer's disease and Parkinson's disease; distinct entities or extremes of a spectrum of neurodegeneration? Ann. Neurol. (suppl.) 44, S19-S31 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Perl, D.P.1
Olanow, C.W.2
Calne, D.B.3
-
5
-
-
0031670136
-
Genetics of Parkinson's disease
-
Gasser, T. Genetics of Parkinson's disease. Ann. Neurol. 44, S53-S57 (1998).
-
(1998)
Ann. Neurol.
, vol.44
-
-
Gasser, T.1
-
6
-
-
0033608187
-
Parkinson's disease in twins: An etiologic study
-
Tanner, C. M. et al. Parkinson's disease in twins: an etiologic study. J. Am. Med. Assoc. 281, 341-346 (1999).
-
(1999)
J. Am. Med. Assoc.
, vol.281
, pp. 341-346
-
-
Tanner, C.M.1
-
7
-
-
0031668924
-
The early diagnosis of Parkinson's disease
-
Brooks, D. J. The early diagnosis of Parkinson's disease. Ann. Neurol. (suppl.) 44, S10-S18 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Brooks, D.J.1
-
8
-
-
0031715849
-
Epidemiology versus genetics in Parkinson's disease: Progress in resolving an age-old debate
-
Langston, J. W. Epidemiology versus genetics in Parkinson's disease: progress in resolving an age-old debate. Ann. Neurol. (suppl.) 44, S45-S52 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Langston, J.W.1
-
9
-
-
0030882856
-
α-Synuclein in Lewy bodies
-
Spillantini, M. G. et al. α-Synuclein in Lewy bodies. Nature 388, 839-890 (1997).
-
(1997)
Nature
, vol.388
, pp. 839-890
-
-
Spillantini, M.G.1
-
10
-
-
0031824780
-
α-Synuclein in neurodegenerative disorders: Murderer or accomplice?
-
Mezey, E. et al. α-Synuclein in neurodegenerative disorders: murderer or accomplice? Nature Med. 4, 755-757 (1998).
-
(1998)
Nature Med.
, vol.4
, pp. 755-757
-
-
Mezey, E.1
-
11
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant α-synuclein linked to early onset Parkinson's disease
-
Conway, K. A., Harper, J. D. & Lansbury, P. T. Accelerated in vitro fibril formation by a mutant α-synuclein linked to early onset Parkinson's disease. Nature Med. 4, 1318-1320 (1998).
-
(1998)
Nature Med.
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
12
-
-
0002508690
-
-
(eds Watts, R. L. & Koller, W. C.) McGraw-Hill, New York
-
Poewe, W. & Granata, R. in Movement Disorders. Neurological Principles and Practice (eds Watts, R. L. & Koller, W. C.) 201-219 (McGraw-Hill, New York, 1997).
-
(1997)
Movement Disorders. Neurological Principles and Practice
, pp. 201-219
-
-
Poewe, W.1
Granata, R.2
-
13
-
-
0017344150
-
Success and problems of long-term levodopa therapy in Parkinson's disease
-
Marsden, C. D. & Parkes, J. D. Success and problems of long-term levodopa therapy in Parkinson's disease. Lancet 1, 345-349 (1977).
-
(1977)
Lancet
, vol.1
, pp. 345-349
-
-
Marsden, C.D.1
Parkes, J.D.2
-
14
-
-
0030632235
-
An introduction to the new surgery for Parkinson's disease: Past and present problems
-
Marsden, C. D., Linazasoro, G. & Obeso, J. A. An introduction to the new surgery for Parkinson's disease: past and present problems. Adv. Neurol. 74, 143-147 (1997).
-
(1997)
Adv. Neurol.
, vol.74
, pp. 143-147
-
-
Marsden, C.D.1
Linazasoro, G.2
Obeso, J.A.3
-
15
-
-
0025298139
-
Primate models of movement disorders of basal ganglia origin
-
DeLong, M. R. Primate models of movement disorders of basal ganglia origin. Trends Neurosci. 13, 281-285 (1990).
-
(1990)
Trends Neurosci.
, vol.13
, pp. 281-285
-
-
DeLong, M.R.1
-
16
-
-
0031756782
-
Ablative surgery and deep brain stimulation for Parkinson's disease
-
Starr, P. A., Vitek, J. L. & Bakay, R. A. E. Ablative surgery and deep brain stimulation for Parkinson's disease. Neurosurgery 43, 989-1013 (1998).
-
(1998)
Neurosurgery
, vol.43
, pp. 989-1013
-
-
Starr, P.A.1
Vitek, J.L.2
Bakay, R.A.E.3
-
17
-
-
0030624095
-
Chronic intracerebral stimulation in Parkinson's disease
-
Pollak, P., Benabid, A. L., Limousin, P. & Benazzouz, A. Chronic intracerebral stimulation in Parkinson's disease. Adv. Neurol. 74, 213-220 (1997).
-
(1997)
Adv. Neurol.
, vol.74
, pp. 213-220
-
-
Pollak, P.1
Benabid, A.L.2
Limousin, P.3
Benazzouz, A.4
-
18
-
-
0015745743
-
Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
-
Bernheimer, H., Birkmayer, W., Hornykiewicz, O., Jellinger, K. & Seitelberger, F. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J. Neurol. Sci. 20, 415-455 (1973).
-
(1973)
J. Neurol. Sci.
, vol.20
, pp. 415-455
-
-
Bernheimer, H.1
Birkmayer, W.2
Hornykiewicz, O.3
Jellinger, K.4
Seitelberger, F.5
-
19
-
-
0025954066
-
Parkinson's disease: Neuropathology
-
Fearnley, J. & Lees, A. J. Parkinson's disease: neuropathology. Brain 114, 2283-2301 (1991).
-
(1991)
Brain
, vol.114
, pp. 2283-2301
-
-
Fearnley, J.1
Lees, A.J.2
-
20
-
-
0023740773
-
Rate of cell death in parkinsonism indicates active neuropathological process
-
McGeer, P. L., Itagaki, S., Akiyama, H. & McGeer, E. G. Rate of cell death in parkinsonism indicates active neuropathological process. Ann. Neurol. 24, 574-576 (1989).
-
(1989)
Ann. Neurol.
, vol.24
, pp. 574-576
-
-
McGeer, P.L.1
Itagaki, S.2
Akiyama, H.3
McGeer, E.G.4
-
21
-
-
0021089452
-
Aetiology of Parkinson's disease
-
Calne, D. B. & Langston, J. W. Aetiology of Parkinson's disease. Lancet 2, 1457-1459 (1983).
-
(1983)
Lancet
, vol.2
, pp. 1457-1459
-
-
Calne, D.B.1
Langston, J.W.2
-
23
-
-
0040982601
-
-
(eds Watts, R. L. & Koller, W. C.) McGraw-Hill, New York
-
Mizuno, Y. et al. in Movement Disorders. Neurological Principles and Practice (eds Watts, R. L. & Koller, W. C.) 161-182 (McGraw-Hill, New York, 1997).
-
(1997)
Movement Disorders. Neurological Principles and Practice
, pp. 161-182
-
-
Mizuno, Y.1
-
24
-
-
0031687793
-
Understanding cell death in Parkinson's disease
-
Jenner, P. & Olanow, C. W. Understanding cell death in Parkinson's disease. Ann. Neurol. (suppl.) 44, S72-S84 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Jenner, P.1
Olanow, C.W.2
-
25
-
-
0030001780
-
Oxidative stress and antioxidant therapy in Parkinson's disease
-
Ebadi, M., Srinivasan, S. K. & Baxi, M. D. Oxidative stress and antioxidant therapy in Parkinson's disease. Prog. Neurobiol. 48, 1-19 (1996).
-
(1996)
Prog. Neurobiol.
, vol.48
, pp. 1-19
-
-
Ebadi, M.1
Srinivasan, S.K.2
Baxi, M.D.3
-
26
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira, A. H. V., Cooper, J. M. & Dexter, D. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1, 1269 (1989).
-
(1989)
Lancet
, vol.1
, pp. 1269
-
-
Schapira, A.H.V.1
Cooper, J.M.2
Dexter, D.3
-
27
-
-
0031668930
-
Programmed cell death: Does it play a role in Parkinson's disease?
-
Burke, R. E. & Kholodilov, N. G. Programmed cell death: does it play a role in Parkinson's disease? Ann. Neurol. (suppl.) 44, S126-S133 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Burke, R.E.1
Kholodilov, N.G.2
-
28
-
-
0031696403
-
A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease
-
Tatton, N. A., Maclean-Fraser, A., Tatton, W. G., Perl, D. P. & Olanow, C. W. A fluorescent double-labeling method to detect and confirm apoptotic nuclei in Parkinson's disease. Ann. Neurol. (suppl.) 44, S142-S148 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Tatton, N.A.1
Maclean-Fraser, A.2
Tatton, W.G.3
Perl, D.P.4
Olanow, C.W.5
-
29
-
-
0031668934
-
The causes of Parkinson's disease are being unraveled and rational neuroprotective therapy is close to reality
-
Marsden, C. D. & Olanow, C. W. The causes of Parkinson's disease are being unraveled and rational neuroprotective therapy is close to reality. Ann. Neurol. (suppl.) 44, S189-S196 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Marsden, C.D.1
Olanow, C.W.2
-
30
-
-
0031893241
-
Mortality in DATATOP: A multicenter trial in early Parkinson's disease
-
Shoulson, I. et al. Mortality in DATATOP: a multicenter trial in early Parkinson's disease. Ann. Neurol. 43, 318-325 (1998).
-
(1998)
Ann. Neurol.
, vol.43
, pp. 318-325
-
-
Shoulson, I.1
-
31
-
-
0031719124
-
Neuroprotection for Parkinson's disease
-
Koller, W. C. Neuroprotection for Parkinson's disease. Ann. Neurol. (suppl.) 44, S155-S159 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Koller, W.C.1
-
32
-
-
0031716026
-
Dopamine agonists and neuroprotection in Parkinson's disease
-
Olanow, C. W., Jenner, P. & Brooks, D. Dopamine agonists and neuroprotection in Parkinson's disease. Ann. Neurol. (suppl.) 44, S167-S174 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Olanow, C.W.1
Jenner, P.2
Brooks, D.3
-
33
-
-
0031696407
-
Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: A target for neuroprotection
-
Rodriguez, M. C., Obeso, J. & Olanow, C. W. Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: a target for neuroprotection. Ann. Neurol. (suppl.) 44, S175-S188 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Rodriguez, M.C.1
Obeso, J.2
Olanow, C.W.3
-
34
-
-
0031888498
-
Neurotrophins prevent death and differentially affect tyrosine hydroxylase of adult rat nigrostriatal neurons in vivo
-
Hagg, T. Neurotrophins prevent death and differentially affect tyrosine hydroxylase of adult rat nigrostriatal neurons in vivo. Exp. Neurol. 149, 183-192 (1998).
-
(1998)
Exp. Neurol.
, vol.149
, pp. 183-192
-
-
Hagg, T.1
-
35
-
-
0030330849
-
Growth factor function in the development and maintenance of midbrain dopaminergic neurons: Concepts, facts and prospects for TGF-β
-
Unsicker, K., Suter-Crazzolara, C. & Krieglstein, K. Growth factor function in the development and maintenance of midbrain dopaminergic neurons: concepts, facts and prospects for TGF-β. Ciba Found. Symp. 196, 70-80 (1996).
-
(1996)
Ciba Found. Symp.
, vol.196
, pp. 70-80
-
-
Unsicker, K.1
Suter-Crazzolara, C.2
Krieglstein, K.3
-
36
-
-
0031662603
-
Neuroprotective and neurorestorative properties of GDNF
-
Gash, D. M., Zhang, Z. M. & Gerhardt, G. Neuroprotective and neurorestorative properties of GDNF. Ann. Neurol. (suppl.) 44, S121-S125 (1998).
-
(1998)
Ann. Neurol. (Suppl.)
, vol.44
-
-
Gash, D.M.1
Zhang, Z.M.2
Gerhardt, G.3
-
37
-
-
0030725572
-
Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease
-
Björklund, A., Rosenblad, C., Winkler, C. & Kirik, D. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiol. Dis. 4, 186-200 (1997).
-
(1997)
Neurobiol. Dis.
, vol.4
, pp. 186-200
-
-
Björklund, A.1
Rosenblad, C.2
Winkler, C.3
Kirik, D.4
-
38
-
-
0003239972
-
Clinical and pathological evaluation of patient with Parkinson's disease (PD) following intracerebroventricular (icv) GDNF
-
Palfi, S. et al. Clinical and pathological evaluation of patient with Parkinson's disease (PD) following intracerebroventricular (icv) GDNF. Soc. Neurosci. Abstr. 24, 41 (1998).
-
(1998)
Soc. Neurosci. Abstr.
, vol.24
, pp. 41
-
-
Palfi, S.1
-
39
-
-
0031594542
-
Neural actions of immunophilin ligands
-
Snyder, S. H. et al. Neural actions of immunophilin ligands. Trends Pharmacol. Sci. 19, 21-26 (1998).
-
(1998)
Trends Pharmacol. Sci.
, vol.19
, pp. 21-26
-
-
Snyder, S.H.1
-
40
-
-
12644257556
-
Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models
-
Steiner, J. P., Hamilton, G. S., Ross, D. T. & Valentine, H. L. Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models. Proc. Natl Acad. Sci. USA 94, 2019-2124 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 2019-2124
-
-
Steiner, J.P.1
Hamilton, G.S.2
Ross, D.T.3
Valentine, H.L.4
-
41
-
-
0031660913
-
A novel immunophilin ligand: Distinct branching effects on dopaminergic neurons in culture and neurotrophic actions after oral administration in an animal model of Parkinson's disease
-
Constantini, L. C. et al. A novel immunophilin ligand: distinct branching effects on dopaminergic neurons in culture and neurotrophic actions after oral administration in an animal model of Parkinson's disease. Neurobiol. Dis. 5, 97-106 (1998).
-
(1998)
Neurobiol. Dis.
, vol.5
, pp. 97-106
-
-
Constantini, L.C.1
-
42
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D. R. & Reed, J. C. Mitochondria and apoptosis. Science 281, 1309-1312 (1999).
-
(1999)
Science
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
43
-
-
0033008216
-
Caspase inhibition reduces apoptosis and increases survival of nigral transplants
-
Schierle, G. S. et al. Caspase inhibition reduces apoptosis and increases survival of nigral transplants. Nature Med. 5, 97-100 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 97-100
-
-
Schierle, G.S.1
-
45
-
-
0030873946
-
Neural transplantation: A hope for patients with Parkinson's disease?
-
Lindvall, O. Neural transplantation: a hope for patients with Parkinson's disease? NeuroReport 8, iii-x (1997).
-
(1997)
Neuroreport
, vol.8
-
-
Lindvall, O.1
-
46
-
-
0030632592
-
Neural transplantation as a therapy for Parkinson's disease
-
Olanow, C. W., Freeman, T. B. & Kordower, J. H. Neural transplantation as a therapy for Parkinson's disease. Adv. Neurol. 74, 249-269 (1997).
-
(1997)
Adv. Neurol.
, vol.74
, pp. 249-269
-
-
Olanow, C.W.1
Freeman, T.B.2
Kordower, J.H.3
-
47
-
-
0030834093
-
Short-and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
-
Wenning, G. K. et al. Short-and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Ann. Neurol. 42, 95-107 (1997).
-
(1997)
Ann. Neurol.
, vol.42
, pp. 95-107
-
-
Wenning, G.K.1
-
48
-
-
0031947943
-
Neuropathotogy of fetal nigral grafts in patients with Parkinson's disease
-
Kordower, J. H., Freeman, T. B. & Olanow, C. W. Neuropathotogy of fetal nigral grafts in patients with Parkinson's disease. Mov. Dis. 13, 88-95 (1998).
-
(1998)
Mov. Dis.
, vol.13
, pp. 88-95
-
-
Kordower, J.H.1
Freeman, T.B.2
Olanow, C.W.3
-
49
-
-
0031010545
-
Fetal grafting for Parkinson's disease: Expression of immune markers in two patients with functional fetal nigral implants
-
Kordower, J. H. et al. Fetal grafting for Parkinson's disease: expression of immune markers in two patients with functional fetal nigral implants. Cell Transplant. 6, 213-219 (1997).
-
(1997)
Cell Transplant.
, vol.6
, pp. 213-219
-
-
Kordower, J.H.1
-
50
-
-
0028104614
-
Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research
-
Boer, G. J. Ethical guidelines for the use of human embryonic or fetal tissue for experimental and clinical neurotransplantation and research. J. Neurol. 242, 1-13 (1994).
-
(1994)
J. Neurol.
, vol.242
, pp. 1-13
-
-
Boer, G.J.1
-
51
-
-
0031106244
-
Dopaminergic transplants in patients with Parkinson's disease: Neuroanatomical correlates of clinical recovery
-
Kordower, J. H., Goetz, C. G., Freeman, T. B. & Olanow, C. W. Dopaminergic transplants in patients with Parkinson's disease: neuroanatomical correlates of clinical recovery. Exp. Neurol. 144, 41-46 (1997).
-
(1997)
Exp. Neurol.
, vol.144
, pp. 41-46
-
-
Kordower, J.H.1
Goetz, C.G.2
Freeman, T.B.3
Olanow, C.W.4
-
52
-
-
0032498835
-
Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats
-
Zawada, W. M. et al. Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats. Brain Res. 786, 96-103 (1998).
-
(1998)
Brain Res.
, vol.786
, pp. 96-103
-
-
Zawada, W.M.1
-
53
-
-
0029851904
-
The effects of glial cell line-derived neurotrophic factor (GDNF) on embryonic nigral grafts
-
Sinclair, S. R., Svendsen, C. N., Torres, E. M., Fawcett, J. W. & Dunnett, S. B. The effects of glial cell line-derived neurotrophic factor (GDNF) on embryonic nigral grafts. NeuroReport 7, 2547-2552 (1996).
-
(1996)
Neuroreport
, vol.7
, pp. 2547-2552
-
-
Sinclair, S.R.1
Svendsen, C.N.2
Torres, E.M.3
Fawcett, J.W.4
Dunnett, S.B.5
-
54
-
-
0030298512
-
Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts
-
Rosenblad, C., Martinez-Serrano, A. & Björklund, A. Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. Neuroscience 75, 979-985 (1996).
-
(1996)
Neuroscience
, vol.75
, pp. 979-985
-
-
Rosenblad, C.1
Martinez-Serrano, A.2
Björklund, A.3
-
55
-
-
0032192007
-
Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue
-
Yurek, D. M. Glial cell line-derived neurotrophic factor improves survival of dopaminergic neurons in transplants of fetal ventral mesencephalic tissue. Exp. Neurol. 153, 195-202 (1998).
-
(1998)
Exp. Neurol.
, vol.153
, pp. 195-202
-
-
Yurek, D.M.1
-
56
-
-
0028171918
-
Neural xenotransplantation: Reconstruction of neuronal circuitry across species barriers
-
Pakzaban, P. & Isacson, O. Neural xenotransplantation: reconstruction of neuronal circuitry across species barriers. Neuroscience 62, 989-1001 (1994).
-
(1994)
Neuroscience
, vol.62
, pp. 989-1001
-
-
Pakzaban, P.1
Isacson, O.2
-
57
-
-
0030866841
-
Benefits and risks of hosting animal cells in the human brain
-
Isacson, O. & Breakefield, X. O. Benefits and risks of hosting animal cells in the human brain. Nature Med. 3, 964-969 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 964-969
-
-
Isacson, O.1
Breakefield, X.O.2
-
58
-
-
16944366484
-
Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease
-
Deacon, T. et al. Histological evidence of fetal pig neural cell survival after transplantation into a patient with Parkinson's disease. Nature Med. 3, 350-353 (1997).
-
(1997)
Nature Med.
, vol.3
, pp. 350-353
-
-
Deacon, T.1
-
59
-
-
0032556891
-
Last chance to stop and think on risks of xenotransplants
-
Butler, D. Last chance to stop and think on risks of xenotransplants. Nature 391, 320-324 (1998).
-
(1998)
Nature
, vol.391
, pp. 320-324
-
-
Butler, D.1
-
60
-
-
0027407368
-
Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors
-
Mayer, E., Dunnett, S. B. & Fawcett, J. W. Mitogenic effect of basic fibroblast growth factor on embryonic ventral mesencephalic dopaminergic neurone precursors. Dev. Brain. Res. 72, 253-258 (1993).
-
(1993)
Dev. Brain. Res.
, vol.72
, pp. 253-258
-
-
Mayer, E.1
Dunnett, S.B.2
Fawcett, J.W.3
-
61
-
-
0028882094
-
Basic fibroblast growth factor increases division and delays differentiation of dopamine precursors in vitro
-
Bouvier, M. M. & Mytilineou, C. Basic fibroblast growth factor increases division and delays differentiation of dopamine precursors in vitro. J. Neurosci. 15, 7141-7149 (1995).
-
(1995)
J. Neurosci.
, vol.15
, pp. 7141-7149
-
-
Bouvier, M.M.1
Mytilineou, C.2
-
62
-
-
33644684826
-
Transplantaton of expanded mesencephalic precursors leads to recovery in parkinsonian rats
-
Studer, L., Tabar, V. & McKay, R. D. G. Transplantaton of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nature Neurosci. 1, 290-295 (1998).
-
(1998)
Nature Neurosci.
, vol.1
, pp. 290-295
-
-
Studer, L.1
Tabar, V.2
McKay, R.D.G.3
-
63
-
-
0032007097
-
Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines
-
Ling, Z. D., Potter, E. D., Lipton, J. W. & Carvey, P. M. Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines. Exp. Neurol. 149, 411-423 (1998).
-
(1998)
Exp. Neurol.
, vol.149
, pp. 411-423
-
-
Ling, Z.D.1
Potter, E.D.2
Lipton, J.W.3
Carvey, P.M.4
-
64
-
-
0032577445
-
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
-
Ye, W. L., Shimamura, K., Rubenstein, J. L. R., Hynes, M. A. & Rosenthal, A. FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell 93, 755-766 (1998).
-
(1998)
Cell
, vol.93
, pp. 755-766
-
-
Ye, W.L.1
Shimamura, K.2
Rubenstein, J.L.R.3
Hynes, M.A.4
Rosenthal, A.5
-
65
-
-
0003057732
-
-
(eds Dunnett, S. B. & Björklund, A.) Raven, New York
-
Brundin, P., Duan, W.-M. & Sauer, H. in Functional Neural Transplantation (eds Dunnett, S. B. & Björklund, A.) 9-46 (Raven, New York, 1994).
-
(1994)
Functional Neural Transplantation
, pp. 9-46
-
-
Brundin, P.1
Duan, W.-M.2
Sauer, H.3
-
66
-
-
0025935786
-
United Parkinson Foundation neurotransplantation registry on adrenal medullary transplants: Presurgical, and 1-year and 2-year follow up
-
Goetz, C. G. et al. United Parkinson Foundation neurotransplantation registry on adrenal medullary transplants: presurgical, and 1-year and 2-year follow up. Neurology 41, 1719-1722 (1991).
-
(1991)
Neurology
, vol.41
, pp. 1719-1722
-
-
Goetz, C.G.1
-
67
-
-
0024433446
-
An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats
-
Winn, S. R., Wahlberg, L., Tresco, P. A. & Aebischer, P. An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats. Exp. Neurol. 105, 244-250 (1989).
-
(1989)
Exp. Neurol.
, vol.105
, pp. 244-250
-
-
Winn, S.R.1
Wahlberg, L.2
Tresco, P.A.3
Aebischer, P.4
-
68
-
-
0025190819
-
Sustained behavioral recovery from unilateral nigrostriatal damage produced by the controlled release of dopamine from a silicone polymer pellet placed into the denervated striatum
-
Becker, J. B et al. Sustained behavioral recovery from unilateral nigrostriatal damage produced by the controlled release of dopamine from a silicone polymer pellet placed into the denervated striatum. Brain Res. 508, 60-64 (1990).
-
(1990)
Brain Res.
, vol.508
, pp. 60-64
-
-
Becker, J.B.1
-
69
-
-
0028214265
-
Functional recovery in hemiparkinsonian primates transplanted with polymer-encapsulated PC12 cells
-
Aebischer, P., Goddard, M., Signore, A. P. & Timpson, R. L. Functional recovery in hemiparkinsonian primates transplanted with polymer-encapsulated PC12 cells. Exp. Neurol. 126, 151-158 (1994).
-
(1994)
Exp. Neurol.
, vol.126
, pp. 151-158
-
-
Aebischer, P.1
Goddard, M.2
Signore, A.P.3
Timpson, R.L.4
-
70
-
-
0027308140
-
Polymer-encapsulated PC12 cells promote recovery of motor function in aged rats
-
Emerich, D. F. et al. Polymer-encapsulated PC12 cells promote recovery of motor function in aged rats. Exp. Neurol. 122, 37-47 (1993).
-
(1993)
Exp. Neurol.
, vol.122
, pp. 37-47
-
-
Emerich, D.F.1
-
71
-
-
0032005461
-
Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantaton of carotid body cell aggregates
-
Espejo, E. F., Montoro, R. J., Armengol, J. A. & López-Barneo, J. Cellular and functional recovery of Parkinsonian rats after intrastriatal transplantaton of carotid body cell aggregates. Neuron 20, 197-206 (1998).
-
(1998)
Neuron
, vol.20
, pp. 197-206
-
-
Espejo, E.F.1
Montoro, R.J.2
Armengol, J.A.3
López-Barneo, J.4
-
72
-
-
0025963275
-
Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce 1-DOPA
-
Fisher, L. J., Jinnah, H. A., Kale, L. C., Higgins, G. A. & Gage, F. H. Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce 1-DOPA. Neuron 6, 371-380 (1991).
-
(1991)
Neuron
, vol.6
, pp. 371-380
-
-
Fisher, L.J.1
Jinnah, H.A.2
Kale, L.C.3
Higgins, G.A.4
Gage, F.H.5
-
73
-
-
0029973056
-
Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxytase gene: In vitro characterisation and in vivo effects in the rat Parkinson model
-
Lundberg, C., Horellou, P., Mallet, J. & Björklund, A. Generation of DOPA-producing astrocytes by retroviral transduction of the human tyrosine hydroxytase gene: in vitro characterisation and in vivo effects in the rat Parkinson model. Exp. Neurol. 139, 39-53 (1996).
-
(1996)
Exp. Neurol.
, vol.139
, pp. 39-53
-
-
Lundberg, C.1
Horellou, P.2
Mallet, J.3
Björklund, A.4
-
74
-
-
0028169809
-
Neural-targeted gene therapy for rodent and primate hemiparkinsonism
-
Anton, R. et al. Neural-targeted gene therapy for rodent and primate hemiparkinsonism. Exp. Neurol. 127, 207-218 (1994).
-
(1994)
Exp. Neurol.
, vol.127
, pp. 207-218
-
-
Anton, R.1
-
75
-
-
0024820634
-
Rationale for continuous dopaminomimetic therapy of Parkinson's disease
-
Chase, T. N. et al. Rationale for continuous dopaminomimetic therapy of Parkinson's disease. Neurology 39, 7-10 (1989).
-
(1989)
Neurology
, vol.39
, pp. 7-10
-
-
Chase, T.N.1
-
76
-
-
0031105522
-
Application of ex vivo gene therapy in the treatment of Parkinson's disease
-
Raymon, H. K., Thode, S. & Gage, F. H. Application of ex vivo gene therapy in the treatment of Parkinson's disease. Exp. Neurol. 144, 82-91 (1997).
-
(1997)
Exp. Neurol.
, vol.144
, pp. 82-91
-
-
Raymon, H.K.1
Thode, S.2
Gage, F.H.3
-
77
-
-
0031945063
-
Potential of gene therapy for Parkinson's disease: Neurobiologic issues and new developments in gene transfer methodologies
-
Kang, U. J. Potential of gene therapy for Parkinson's disease: neurobiologic issues and new developments in gene transfer methodologies. Mov. Dis. 13, 59-72 (1998).
-
(1998)
Mov. Dis.
, vol.13
, pp. 59-72
-
-
Kang, U.J.1
-
78
-
-
0030006065
-
Double transduction with GTP cyclohydrolase L and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts
-
Bencsics, C. et al. Double transduction with GTP cyclohydrolase L and tyrosine hydroxylase is necessary for spontaneous synthesis of L-DOPA by primary fibroblasts. J. Neurosci. 16, 4449-4456 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 4449-4456
-
-
Bencsics, C.1
-
79
-
-
0032102936
-
In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via compression of GTP cyclohydrolase 1 with tyrosine hydroxylase
-
Left, S. E., Rendahl, K. G., Spratt, S. K., Kang, U. J. & Mandel, R. J. In vivo L-DOPA production by genetically modified primary rat fibroblast or 9L gliosarcoma cell grafts via compression of GTP cyclohydrolase 1 with tyrosine hydroxylase. Exp. Neurol. 151, 249-264 (1998).
-
(1998)
Exp. Neurol.
, vol.151
, pp. 249-264
-
-
Left, S.E.1
Rendahl, K.G.2
Spratt, S.K.3
Kang, U.J.4
Mandel, R.J.5
-
80
-
-
0027970324
-
Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat
-
Barker, R. A & Dunnett, S. B. Ibotenic acid lesions of the striatum reduce drug-induced rotation in the 6-hydroxydopamine-lesioned rat. Exp. Brain Res. 101, 365-374 (1994).
-
(1994)
Exp. Brain Res.
, vol.101
, pp. 365-374
-
-
Barker, R.A.1
Dunnett, S.B.2
-
81
-
-
0029097513
-
Behavioral effects and gene delivery in a rat model of Parkinson's disease
-
Isacson, O. Behavioral effects and gene delivery in a rat model of Parkinson's disease. Science 269, 856-856 (1995).
-
(1995)
Science
, vol.269
, pp. 856-856
-
-
Isacson, O.1
-
82
-
-
0028276809
-
Implanted fibroblasts genetically engineered to produce brain derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat
-
Frim, D. M. et al. Implanted fibroblasts genetically engineered to produce brain derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat. Proc. Natl Acad. Sci. USA 91, 5104-5108 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 5104-5108
-
-
Frim, D.M.1
-
83
-
-
0029610630
-
Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease
-
Levivier, M., Przedborski, S., Bencsics, C. & Kang, U. J. Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease. J. Neurosci. 15, 7810-7820 (1995).
-
(1995)
J. Neurosci.
, vol.15
, pp. 7810-7820
-
-
Levivier, M.1
Przedborski, S.2
Bencsics, C.3
Kang, U.J.4
-
84
-
-
0031031008
-
GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine
-
Tseng, J. L., Baetge, E. E., Zurn, A. D. & Aebischer, P. GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine. J. Neurosci. 17, 325-333 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 325-333
-
-
Tseng, J.L.1
Baetge, E.E.2
Zurn, A.D.3
Aebischer, P.4
-
85
-
-
0031019795
-
Dopaminergic neurons protected from degeneration by GDNF gene therapy
-
Choi-Lundberg, D. L. et al. Dopaminergic neurons protected from degeneration by GDNF gene therapy. Science 275, 838-841 (1997).
-
(1997)
Science
, vol.275
, pp. 838-841
-
-
Choi-Lundberg, D.L.1
-
86
-
-
0031456051
-
Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats
-
Mandel, R. J., Spratt, S. K., Snyder, R. O. & Leff, S. E. Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model of Parkinson's disease in rats. Proc. Natl Acad. Sci. USA 94, 14083-14088 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 14083-14088
-
-
Mandel, R.J.1
Spratt, S.K.2
Snyder, R.O.3
Leff, S.E.4
-
87
-
-
0030795798
-
Intrastriatal injection of an adenoviral vector expressing glial cell line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson's disease
-
Bilang-Bleuel, A. et al. Intrastriatal injection of an adenoviral vector expressing glial cell line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson's disease. Proc. Natl Acad. Sci. USA 94, 8818-8823 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 8818-8823
-
-
Bilang-Bleuel, A.1
-
88
-
-
0032423612
-
Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor
-
Choi-Lundberg, D. L. et al. Behavioral and cellular protection of rat dopaminergic neurons by an adenoviral vector encoding glial cell line-derived neurotrophic factor. Exp. Neurol. 154, 261-275 (1998).
-
(1998)
Exp. Neurol.
, vol.154
, pp. 261-275
-
-
Choi-Lundberg, D.L.1
-
89
-
-
0032478257
-
Bcl-xL protects adult septal cholinergic neurons from axotomized cell death
-
Blömer, U., Kafri, T., Randolph-Moore, L., Verma, I. M. & Gage, F. H. Bcl-xL protects adult septal cholinergic neurons from axotomized cell death. Proc. Natl Acad. Sci. USA 95, 2603-2608 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 2603-2608
-
-
Blömer, U.1
Kafri, T.2
Randolph-Moore, L.3
Verma, I.M.4
Gage, F.H.5
-
90
-
-
0029071968
-
Expression of human copper/zinc-superoxide dismutase inhibits the death of rat sympathetic neurons caused by withdrawal of nerve growth-factor
-
Jordan, J. et al. Expression of human copper/zinc-superoxide dismutase inhibits the death of rat sympathetic neurons caused by withdrawal of nerve growth-factor. Mol. Pharmacol. 47, 1095-1100 (1995).
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 1095-1100
-
-
Jordan, J.1
-
91
-
-
0029981856
-
18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease
-
18F]dopa-PET and clinical study of the rate of progression in Parkinson's disease. Brain 119, 585-591 (1996).
-
(1996)
Brain
, vol.119
, pp. 585-591
-
-
Morrish, P.K.1
Sawle, G.V.2
Brooks, D.J.3
-
92
-
-
0027944855
-
Metals and free radicals in neurodegeneration
-
Olanow, C. W. & Arendash, G. W. Metals and free radicals in neurodegeneration. Curr. Opin. Neurol. 7, 548-558 (1994).
-
(1994)
Curr. Opin. Neurol.
, vol.7
, pp. 548-558
-
-
Olanow, C.W.1
Arendash, G.W.2
-
93
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M. H. et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276, 2045-2047 (1997).
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
-
94
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T. et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608 (1998).
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
-
95
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy, M. et al. The ubiquitin pathway in Parkinson's disease. Nature 395, 451-452 (1998).
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, M.1
-
96
-
-
2642607011
-
Low frequency of α-synuclein mutations in familial Parkinson's disease
-
Farrer, M. et al. Low frequency of α-synuclein mutations in familial Parkinson's disease. Ann. Neurol. 43, 394-397 (1998).
-
(1998)
Ann. Neurol.
, vol.43
, pp. 394-397
-
-
Farrer, M.1
-
97
-
-
0031951197
-
A susceptibility locus for Parkinson's disease maps to chromosome 2p13
-
Gasser, T. et al. A susceptibility locus for Parkinson's disease maps to chromosome 2p13. Nature Genet. 18, 262-265 (1998).
-
(1998)
Nature Genet.
, vol.18
, pp. 262-265
-
-
Gasser, T.1
-
98
-
-
0031990490
-
Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease
-
Kruger, R. et al. Ala30Pro mutation in the gene encoding α-synuclein in Parkinson's disease. Nature Genet. 18, 106-108 (1998).
-
(1998)
Nature Genet.
, vol.18
, pp. 106-108
-
-
Kruger, R.1
-
99
-
-
0040982604
-
-
(ed. Trosyter, A. I.) Cambridge Univ. Press, Cambridge
-
Owen, A. M., Sahakian, B. J. & Robbins, T. W. in Memory in Neurodegenerative Disease: Biological, Cognitive and Clinical Perspectives (ed. Trosyter, A. I.) 157-171 (Cambridge Univ. Press, Cambridge, 1998).
-
(1998)
Memory in Neurodegenerative Disease: Biological, Cognitive and Clinical Perspectives
, pp. 157-171
-
-
Owen, A.M.1
Sahakian, B.J.2
Robbins, T.W.3
|