-
1
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha
-
D.R. Alessi, S.R. James, C.P. Downes, A.B. Holmes, P.R. Gaffney, C.B. Reese, and P. Cohen Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha Curr. Biol. 7 1997 261 269
-
(1997)
Curr. Biol.
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
2
-
-
0033603208
-
Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4
-
R. Bohni, J. Riesgo-Escovar, S. Oldham, W. Brogiolo, H. Stocker, B.F. Andruss, K. Beckingham, and E. Hafen Autonomous control of cell and organ size by CHICO, a Drosophila homolog of vertebrate IRS1-4 Cell 97 1999 865 875
-
(1999)
Cell
, vol.97
, pp. 865-875
-
-
Bohni, R.1
Riesgo-Escovar, J.2
Oldham, S.3
Brogiolo, W.4
Stocker, H.5
Andruss, B.F.6
Beckingham, K.7
Hafen, E.8
-
3
-
-
0142217556
-
DJ-1(PARK7), a novel gene for autosomal recessive, early onset parkinsonism
-
V. Bonifati, P. Rizzu, F. Squitieri, E. Krieger, N. Vanacore, J.C. van Swieten, A. Brice, C.M. van Duijn, B. Oostra, G. Meco, and P. Heutink DJ-1(PARK7), a novel gene for autosomal recessive, early onset parkinsonism Neurol. Sci. 24 2003 159 160
-
(2003)
Neurol. Sci.
, vol.24
, pp. 159-160
-
-
Bonifati, V.1
Rizzu, P.2
Squitieri, F.3
Krieger, E.4
Vanacore, N.5
Van Swieten, J.C.6
Brice, A.7
Van Duijn, C.M.8
Oostra, B.9
Meco, G.10
Heutink, P.11
-
4
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
V. Bonifati, P. Rizzu, M.J. van Baren, O. Schaap, G.J. Breedveld, E. Krieger, M.C. Dekker, F. Squitieri, P. Ibanez, and M. Joosse Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism Science 299 2003 256 259
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
-
5
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
A.H. Brand, and N. Perrimon Targeted gene expression as a means of altering cell fates and generating dominant phenotypes Development 118 1993 401 415
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
6
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
B.M. Burgering, and P.J. Coffer Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction Nature 376 1995 599 602
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
7
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
R.M. Canet-Aviles, M.A. Wilson, D.W. Miller, R. Ahmad, C. McLendon, S. Bandyopadhyay, M.J. Baptista, D. Ringe, G.A. Petsko, and M.R. Cookson The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization Proc. Natl. Acad. Sci. USA 101 2004 9103 9108
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
8
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
L.C. Cantley, and B.G. Neel New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway Proc. Natl. Acad. Sci. USA 96 1999 4240 4245
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
9
-
-
0016766716
-
The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans
-
R.C. Cassada, and R.L. Russell The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans Dev. Biol. 46 1975 326 342
-
(1975)
Dev. Biol.
, vol.46
, pp. 326-342
-
-
Cassada, R.C.1
Russell, R.L.2
-
11
-
-
0032533225
-
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
-
J.A. Diehl, M. Cheng, M.F. Roussel, and C.J. Sherr Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization Genes Dev. 12 1998 3499 3511
-
(1998)
Genes Dev.
, vol.12
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
12
-
-
0031831731
-
PTEN and inherited hamartoma-cancer syndromes
-
C. Eng, and M. Peacocke PTEN and inherited hamartoma-cancer syndromes Nat. Genet. 19 1998 223
-
(1998)
Nat. Genet.
, vol.19
, pp. 223
-
-
Eng, C.1
Peacocke, M.2
-
13
-
-
0033003079
-
Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma
-
H.E. Feilotter, V. Coulon, J.L. McVeigh, A.H. Boag, F. Dorion-Bonnet, B. Duboue, W.C. Latham, C. Eng, L.M. Mulligan, and M. Longy Analysis of the 10q23 chromosomal region and the PTEN gene in human sporadic breast carcinoma Br. J. Cancer 79 1999 718 723
-
(1999)
Br. J. Cancer
, vol.79
, pp. 718-723
-
-
Feilotter, H.E.1
Coulon, V.2
McVeigh, J.L.3
Boag, A.H.4
Dorion-Bonnet, F.5
Duboue, B.6
Latham, W.C.7
Eng, C.8
Mulligan, L.M.9
Longy, M.10
-
14
-
-
0033001584
-
Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas
-
D. Freihoff, A. Kempe, B. Beste, B. Wappenschmidt, E. Kreyer, Y. Hayashi, A. Meindl, D. Krebs, O.D. Wiestler, A. von Deimling, and R.K. Schmutzler Exclusion of a major role for the PTEN tumour-suppressor gene in breast carcinomas Br. J. Cancer 79 1999 754 758
-
(1999)
Br. J. Cancer
, vol.79
, pp. 754-758
-
-
Freihoff, D.1
Kempe, A.2
Beste, B.3
Wappenschmidt, B.4
Kreyer, E.5
Hayashi, Y.6
Meindl, A.7
Krebs, D.8
Wiestler, O.D.9
Von Deimling, A.10
Schmutzler, R.K.11
-
16
-
-
3643119742
-
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells
-
F.B. Furnari, H.J. Huang, and W.K. Cavenee The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells Cancer Res. 58 1998 5002 5008
-
(1998)
Cancer Res.
, vol.58
, pp. 5002-5008
-
-
Furnari, F.B.1
Huang, H.J.2
Cavenee, W.K.3
-
17
-
-
0034657764
-
Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways
-
X. Gao, T.P. Neufeld, and D. Pan Drosophila PTEN regulates cell growth and proliferation through PI3K-dependent and -independent pathways Dev. Biol. 221 2000 404 418
-
(2000)
Dev. Biol.
, vol.221
, pp. 404-418
-
-
Gao, X.1
Neufeld, T.P.2
Pan, D.3
-
18
-
-
0033572644
-
Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway
-
D.C. Goberdhan, N. Paricio, E.C. Goodman, M. Mlodzik, and C. Wilson Drosophila tumor suppressor PTEN controls cell size and number by antagonizing the Chico/PI3-kinase signaling pathway Genes Dev. 13 1999 3244 3258
-
(1999)
Genes Dev.
, vol.13
, pp. 3244-3258
-
-
Goberdhan, D.C.1
Paricio, N.2
Goodman, E.C.3
Mlodzik, M.4
Wilson, C.5
-
19
-
-
0028334880
-
Daf-2, daf-16 and daf-23: Genetically interacting genes controlling Dauer formation in Caenorhabditis elegans
-
S. Gottlieb, and G. Ruvkun daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans Genetics 137 1994 107 120
-
(1994)
Genetics
, vol.137
, pp. 107-120
-
-
Gottlieb, S.1
Ruvkun, G.2
-
20
-
-
16644381913
-
Differential control of apoptosis by DJ-1 in prostate benign and cancer cells
-
Y. Hod Differential control of apoptosis by DJ-1 in prostate benign and cancer cells J. Cell. Biochem. 92 2004 1221 1233
-
(2004)
J. Cell. Biochem.
, vol.92
, pp. 1221-1233
-
-
Hod, Y.1
-
21
-
-
0033103726
-
Identification and characterization of a novel protein that regulates RNA-protein interaction
-
Y. Hod, S.N. Pentyala, T.C. Whyard, and M.R. El-Maghrabi Identification and characterization of a novel protein that regulates RNA-protein interaction J. Cell. Biochem. 72 1999 435 444
-
(1999)
J. Cell. Biochem.
, vol.72
, pp. 435-444
-
-
Hod, Y.1
Pentyala, S.N.2
Whyard, T.C.3
El-Maghrabi, M.R.4
-
22
-
-
0042232029
-
The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease
-
K. Honbou, N.N. Suzuki, M. Horiuchi, T. Niki, T. Taira, H. Ariga, and F. Inagaki The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease J. Biol. Chem. 278 2003 31380 31384
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31380-31384
-
-
Honbou, K.1
Suzuki, N.N.2
Horiuchi, M.3
Niki, T.4
Taira, T.5
Ariga, H.6
Inagaki, F.7
-
23
-
-
0042063899
-
Crystal structure of DJ-1/RS and implication on familial Parkinson's disease
-
Q. Huai, Y. Sun, H. Wang, L.S. Chin, L. Li, H. Robinson, and H. Ke Crystal structure of DJ-1/RS and implication on familial Parkinson's disease FEBS Lett. 549 2003 171 175
-
(2003)
FEBS Lett.
, vol.549
, pp. 171-175
-
-
Huai, Q.1
Sun, Y.2
Wang, H.3
Chin, L.S.4
Li, L.5
Robinson, H.6
Ke, H.7
-
24
-
-
0033376684
-
PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development
-
H. Huang, C.J. Potter, W. Tao, D.M. Li, W. Brogiolo, E. Hafen, H. Sun, and T. Xu PTEN affects cell size, cell proliferation and apoptosis during Drosophila eye development Development 126 1999 5365 5372
-
(1999)
Development
, vol.126
, pp. 5365-5372
-
-
Huang, H.1
Potter, C.J.2
Tao, W.3
Li, D.M.4
Brogiolo, W.5
Hafen, E.6
Sun, H.7
Xu, T.8
-
25
-
-
0032081541
-
A heterozygous frameshift mutation of the PTEN/MMAC1 gene in a patient with Lhermitte-Duclos disease - Only the mutated allele was expressed in the cerebellar tumor
-
S. Iida, Y. Tanaka, H. Fujii, S. Hayashi, M. Kimura, T. Nagareda, and K. Moriwaki A heterozygous frameshift mutation of the PTEN/MMAC1 gene in a patient with Lhermitte-Duclos disease - only the mutated allele was expressed in the cerebellar tumor Int. J. Mol. Med. 1 1998 925 929
-
(1998)
Int. J. Mol. Med.
, vol.1
, pp. 925-929
-
-
Iida, S.1
Tanaka, Y.2
Fujii, H.3
Hayashi, S.4
Kimura, M.5
Nagareda, T.6
Moriwaki, K.7
-
26
-
-
0036889905
-
Clinical relevance of molecular markers in lung cancer
-
P. Iyengar, and M.S. Tsao Clinical relevance of molecular markers in lung cancer Surg. Oncol. 11 2002 167 179
-
(2002)
Surg. Oncol.
, vol.11
, pp. 167-179
-
-
Iyengar, P.1
Tsao, M.S.2
-
27
-
-
0037378026
-
Oxidative stress in Parkinson's disease
-
P. Jenner Oxidative stress in Parkinson's disease Ann. Neurol. 53 2003 S26 S36
-
(2003)
Ann. Neurol.
, vol.53
-
-
Jenner, P.1
-
29
-
-
14144252004
-
Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic
-
S. Kang, A.G. Bader, and P.K. Vogt Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic Proc. Natl. Acad. Sci. USA 102 2005 802 807
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 802-807
-
-
Kang, S.1
Bader, A.G.2
Vogt, P.K.3
-
30
-
-
0035187302
-
Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer
-
F. Le Naour, D.E. Misek, M.C. Krause, L. Deneux, T.J. Giordano, S. Scholl, and S.M. Hanash Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer Clin. Cancer Res. 7 2001 3328 3335
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 3328-3335
-
-
Le Naour, F.1
Misek, D.E.2
Krause, M.C.3
Deneux, L.4
Giordano, T.J.5
Scholl, S.6
Hanash, S.M.7
-
31
-
-
20044388328
-
PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas
-
J.W. Lee, Y.H. Soung, S.Y. Kim, H.W. Lee, W.S. Park, S.W. Nam, S.H. Kim, J.Y. Lee, N.J. Yoo, and S.H. Lee PIK3CA gene is frequently mutated in breast carcinomas and hepatocellular carcinomas Oncogene 24 2005 1477 1480
-
(2005)
Oncogene
, vol.24
, pp. 1477-1480
-
-
Lee, J.W.1
Soung, Y.H.2
Kim, S.Y.3
Lee, H.W.4
Park, W.S.5
Nam, S.W.6
Kim, S.H.7
Lee, J.Y.8
Yoo, N.J.9
Lee, S.H.10
-
32
-
-
0242497815
-
Crystal Structures of Human DJ-1 and Escherichia coli Hsp31, Which Share an Evolutionarily Conserved Domain
-
S.J. Lee, S.J. Kim, I.K. Kim, J. Ko, C.S. Jeong, G.H. Kim, C. Park, S.O. Kang, P.G. Suh, H.S. Lee, and S.S. Cha Crystal Structures of Human DJ-1 and Escherichia coli Hsp31, Which Share an Evolutionarily Conserved Domain J. Biol. Chem. 278 2003 44552 44559
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44552-44559
-
-
Lee, S.J.1
Kim, S.J.2
Kim, I.K.3
Ko, J.4
Jeong, C.S.5
Kim, G.H.6
Park, C.7
Kang, S.O.8
Suh, P.G.9
Lee, H.S.10
Cha, S.S.11
-
33
-
-
0142137134
-
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
-
N.R. Leslie, D. Bennett, Y.E. Lindsay, H. Stewart, A. Gray, and C.P. Downes Redox regulation of PI 3-kinase signalling via inactivation of PTEN EMBO J. 22 2003 5501 5510
-
(2003)
EMBO J.
, vol.22
, pp. 5501-5510
-
-
Leslie, N.R.1
Bennett, D.2
Lindsay, Y.E.3
Stewart, H.4
Gray, A.5
Downes, C.P.6
-
34
-
-
0032431028
-
PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells
-
D.M. Li, and H. Sun PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G1 cell cycle arrest in human glioblastoma cells Proc. Natl. Acad. Sci. USA 95 1998 15406 15411
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15406-15411
-
-
Li, D.M.1
Sun, H.2
-
35
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
D. Liaw, D.J. Marsh, J. Li, P.L. Dahia, S.I. Wang, Z. Zheng, S. Bose, K.M. Call, H.C. Tsou, and M. Peacocke Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome Nat. Genet. 16 1997 64 67
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
-
36
-
-
0142157658
-
Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: Identification of RS/DJ-1 and RhoGDIalpha
-
J.P. MacKeigan, C.M. Clements, J.D. Lich, R.M. Pope, Y. Hod, and J.P. Ting Proteomic profiling drug-induced apoptosis in non-small cell lung carcinoma: identification of RS/DJ-1 and RhoGDIalpha Cancer Res. 63 2003 6928 6934
-
(2003)
Cancer Res.
, vol.63
, pp. 6928-6934
-
-
MacKeigan, J.P.1
Clements, C.M.2
Lich, J.D.3
Pope, R.M.4
Hod, Y.5
Ting, J.P.6
-
37
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
T. Maehama, and J.E. Dixon The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate J. Biol. Chem. 273 1998 13375 13378
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
38
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
D.J. Marsh, P.L. Dahia, Z. Zheng, D. Liaw, R. Parsons, R.J. Gorlin, and C. Eng Germline mutations in PTEN are present in Bannayan-Zonana syndrome Nat. Genet. 16 1997 333 334
-
(1997)
Nat. Genet.
, vol.16
, pp. 333-334
-
-
Marsh, D.J.1
Dahia, P.L.2
Zheng, Z.3
Liaw, D.4
Parsons, R.5
Gorlin, R.J.6
Eng, C.7
-
39
-
-
0035692636
-
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
-
A. Mitsumoto, and Y. Nakagawa DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin Free Radic. Res. 35 2001 885 893
-
(2001)
Free Radic. Res.
, vol.35
, pp. 885-893
-
-
Mitsumoto, A.1
Nakagawa, Y.2
-
40
-
-
0034906096
-
Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat
-
A. Mitsumoto, Y. Nakagawa, A. Takeuchi, K. Okawa, A. Iwamatsu, and Y. Takanezawa Oxidized forms of peroxiredoxins and DJ-1 on two-dimensional gels increased in response to sublethal levels of paraquat Free Radic. Res. 35 2001 301 310
-
(2001)
Free Radic. Res.
, vol.35
, pp. 301-310
-
-
Mitsumoto, A.1
Nakagawa, Y.2
Takeuchi, A.3
Okawa, K.4
Iwamatsu, A.5
Takanezawa, Y.6
-
41
-
-
0032506011
-
The lipid phosphatase activity of PTEN is critical for its tumor supressor function
-
M.P. Myers, I. Pass, I.H. Batty, J. Van der Kaay, J.P. Stolarov, B.A. Hemmings, M.H. Wigler, C.P. Downes, and N.K. Tonks The lipid phosphatase activity of PTEN is critical for its tumor supressor function Proc. Natl. Acad. Sci. USA 95 1998 13513 13518
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13513-13518
-
-
Myers, M.P.1
Pass, I.2
Batty, I.H.3
Van Der Kaay, J.4
Stolarov, J.P.5
Hemmings, B.A.6
Wigler, M.H.7
Downes, C.P.8
Tonks, N.K.9
-
42
-
-
0031566231
-
DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras
-
D. Nagakubo, T. Taira, H. Kitaura, M. Ikeda, K. Tamai, S.M. Iguchi-Ariga, and H. Ariga DJ-1, a novel oncogene which transforms mouse NIH3T3 cells in cooperation with ras Biochem. Biophys. Res. Commun. 231 1997 509 513
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.231
, pp. 509-513
-
-
Nagakubo, D.1
Taira, T.2
Kitaura, H.3
Ikeda, M.4
Tamai, K.5
Iguchi-Ariga, S.M.6
Ariga, H.7
-
43
-
-
0037291493
-
DJBP: A novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex
-
T. Niki, K. Takahashi-Niki, T. Taira, S.M. Iguchi-Ariga, and H. Ariga DJBP: A novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex Mol. Cancer Res. 1 2003 247 261
-
(2003)
Mol. Cancer Res.
, vol.1
, pp. 247-261
-
-
Niki, T.1
Takahashi-Niki, K.2
Taira, T.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
44
-
-
0036635755
-
DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice
-
M. Okada, K. Matsumoto, T. Niki, T. Taira, S.M. Iguchi-Ariga, and H. Ariga DJ-1, a target protein for an endocrine disrupter, participates in the fertilization in mice Biol. Pharm. Bull. 25 2002 853 856
-
(2002)
Biol. Pharm. Bull.
, vol.25
, pp. 853-856
-
-
Okada, M.1
Matsumoto, K.2
Niki, T.3
Taira, T.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
45
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
A. Perren, L.P. Weng, A.H. Boag, U. Ziebold, K. Thakore, P.L. Dahia, P. Komminoth, J.A. Lees, L.M. Mulligan, G.L. Mutter, and C. Eng Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast Am. J. Pathol. 155 1999 1253 1260
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1253-1260
-
-
Perren, A.1
Weng, L.P.2
Boag, A.H.3
Ziebold, U.4
Thakore, K.5
Dahia, P.L.6
Komminoth, P.7
Lees, J.A.8
Mulligan, L.M.9
Mutter, G.L.10
Eng, C.11
-
46
-
-
0037143711
-
Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila
-
M. Peters, C. DeLuca, A. Hirao, V. Stambolic, J. Potter, L. Zhou, J. Liepa, B. Snow, S. Arya, and J. Wong Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila Proc. Natl. Acad. Sci. USA 99 2002 11305 11310
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 11305-11310
-
-
Peters, M.1
Deluca, C.2
Hirao, A.3
Stambolic, V.4
Potter, J.5
Zhou, L.6
Liepa, J.7
Snow, B.8
Arya, S.9
Wong, J.10
-
47
-
-
13044250465
-
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
-
K. Podsypanina, L.H. Ellenson, A. Nemes, J. Gu, M. Tamura, K.M. Yamada, C. Cordon-Cardo, G. Catoretti, P.E. Fisher, and R. Parsons Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems Proc. Natl. Acad. Sci. USA 96 1999 1563 1568
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
Cordon-Cardo, C.7
Catoretti, G.8
Fisher, P.E.9
Parsons, R.10
-
48
-
-
0037453026
-
The 1.6-Å crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad
-
P.M. Quigley, K. Korotkov, F. Baneyx, and W.G. Hol The 1.6-Å crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad Proc. Natl. Acad. Sci. USA 100 2003 3137 3142
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 3137-3142
-
-
Quigley, P.M.1
Korotkov, K.2
Baneyx, F.3
Hol, W.G.4
-
49
-
-
0030801275
-
Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas
-
E. Rhei, L. Kang, F. Bogomolniy, M.G. Federici, P.I. Borgen, and J. Boyd Mutation analysis of the putative tumor suppressor gene PTEN/MMAC1 in primary breast carcinomas Cancer Res. 57 1997 3657 3659
-
(1997)
Cancer Res.
, vol.57
, pp. 3657-3659
-
-
Rhei, E.1
Kang, L.2
Bogomolniy, F.3
Federici, M.G.4
Borgen, P.I.5
Boyd, J.6
-
50
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Y. Samuels, Z. Wang, A. Bardelli, N. Silliman, J. Ptak, S. Szabo, H. Yan, A. Gazdar, S.M. Powell, and G.J. Riggins High frequency of mutations of the PIK3CA gene in human cancers Science 304 2004 554
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
-
51
-
-
13944267769
-
DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation
-
10.1371/journal.pbio.0020362
-
S. Shendelman, A. Jonason, C. Martinat, T. Leete, and A. Abeliovich DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation PLoS Biol. 2 2004 e362 10.1371/journal.pbio.0020362
-
(2004)
PLoS Biol.
, vol.2
, pp. 362
-
-
Shendelman, S.1
Jonason, A.2
Martinat, C.3
Leete, T.4
Abeliovich, A.5
-
52
-
-
0037457314
-
Dysregulated PTEN-PKB and negative receptor status in human breast cancer
-
W. Shi, X. Zhang, M. Pintilie, N. Ma, N. Miller, D. Banerjee, M.S. Tsao, T. Mak, A. Fyles, and F.F. Liu Dysregulated PTEN-PKB and negative receptor status in human breast cancer Int. J. Cancer 104 2003 195 203
-
(2003)
Int. J. Cancer
, vol.104
, pp. 195-203
-
-
Shi, W.1
Zhang, X.2
Pintilie, M.3
Ma, N.4
Miller, N.5
Banerjee, D.6
Tsao, M.S.7
Mak, T.8
Fyles, A.9
Liu, F.F.10
-
53
-
-
0032883802
-
The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes
-
A.C. Spradling, D. Stern, A. Beaton, E.J. Rhem, T. Laverty, N. Mozden, S. Misra, and G.M. Rubin The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes Genetics 153 1999 135 177
-
(1999)
Genetics
, vol.153
, pp. 135-177
-
-
Spradling, A.C.1
Stern, D.2
Beaton, A.3
Rhem, E.J.4
Laverty, T.5
Mozden, N.6
Misra, S.7
Rubin, G.M.8
-
54
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
V. Stambolic, A. Suzuki, J.L. de la Pompa, G.M. Brothers, C. Mirtsos, T. Sasaki, J. Ruland, J.M. Penninger, D.P. Siderovski, and T.W. Mak Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN Cell 95 1998 29 39
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
55
-
-
0034234268
-
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice
-
V. Stambolic, M.S. Tsao, D. Macpherson, A. Suzuki, W.B. Chapman, and T.W. Mak High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice Cancer Res. 60 2000 3605 3611
-
(2000)
Cancer Res.
, vol.60
, pp. 3605-3611
-
-
Stambolic, V.1
Tsao, M.S.2
MacPherson, D.3
Suzuki, A.4
Chapman, W.B.5
Mak, T.W.6
-
56
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
D. Stokoe, L.R. Stephens, T. Copeland, P.R. Gaffney, C.B. Reese, G.F. Painter, A.B. Holmes, F. McCormick, and P.T. Hawkins Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B Science 277 1997 567 570
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
57
-
-
13044305289
-
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
-
H. Sun, R. Lesche, D.M. Li, J. Liliental, H. Zhang, J. Gao, N. Gavrilova, B. Mueller, X. Liu, and H. Wu PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway Proc. Natl. Acad. Sci. USA 96 1999 6199 6204
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6199-6204
-
-
Sun, H.1
Lesche, R.2
Li, D.M.3
Liliental, J.4
Zhang, H.5
Gao, J.6
Gavrilova, N.7
Mueller, B.8
Liu, X.9
Wu, H.10
-
58
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
A. Suzuki, J.L. de la Pompa, V. Stambolic, A.J. Elia, T. Sasaki, I. del Barco Barrantes, A. Ho, A. Wakeham, A. Itie, and W. Khoo High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice Curr. Biol. 8 1998 1169 1178
-
(1998)
Curr. Biol.
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
De La Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
Del Barco Barrantes, I.6
Ho, A.7
Wakeham, A.8
Itie, A.9
Khoo, W.10
-
59
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
T. Taira, Y. Saito, T. Niki, S.M. Iguchi-Ariga, K. Takahashi, and H. Ariga DJ-1 has a role in antioxidative stress to prevent cell death EMBO Rep. 5 2004 213 218
-
(2004)
EMBO Rep.
, vol.5
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.4
Takahashi, K.5
Ariga, H.6
-
60
-
-
0035813135
-
DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor
-
K. Takahashi, T. Taira, T. Niki, C. Seino, S.M. Iguchi-Ariga, and H. Ariga DJ-1 positively regulates the androgen receptor by impairing the binding of PIASx alpha to the receptor J. Biol. Chem. 276 2001 37556 37563
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37556-37563
-
-
Takahashi, K.1
Taira, T.2
Niki, T.3
Seino, C.4
Iguchi-Ariga, S.M.5
Ariga, H.6
-
61
-
-
2942700097
-
Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients
-
K. Takahashi-Niki, T. Niki, T. Taira, S.M. Iguchi-Ariga, and H. Ariga Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients Biochem. Biophys. Res. Commun. 320 2004 389 397
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 389-397
-
-
Takahashi-Niki, K.1
Niki, T.2
Taira, T.3
Iguchi-Ariga, S.M.4
Ariga, H.5
-
62
-
-
4043171279
-
Genetic analysis of DJ-1 in a cohort Parkinson's disease patients of different ethnicity
-
E.K. Tan, C. Tan, Y. Zhao, K. Yew, H. Shen, V.R. Chandran, M.L. Teoh, Y. Yih, R. Pavanni, and M.C. Wong Genetic analysis of DJ-1 in a cohort Parkinson's disease patients of different ethnicity Neurosci. Lett. 367 2004 109 112
-
(2004)
Neurosci. Lett.
, vol.367
, pp. 109-112
-
-
Tan, E.K.1
Tan, C.2
Zhao, Y.3
Yew, K.4
Shen, H.5
Chandran, V.R.6
Teoh, M.L.7
Yih, Y.8
Pavanni, R.9
Wong, M.C.10
-
63
-
-
0034737736
-
Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis
-
D. Tang, J.M. Lahti, and V.J. Kidd Caspase-8 activation and bid cleavage contribute to MCF7 cellular execution in a caspase-3-dependent manner during staurosporine-mediated apoptosis J. Biol. Chem. 275 2000 9303 9307
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 9303-9307
-
-
Tang, D.1
Lahti, J.M.2
Kidd, V.J.3
-
64
-
-
0042232039
-
Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease
-
X. Tao, and L. Tong Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease J. Biol. Chem. 278 2003 31372 31379
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 31372-31379
-
-
Tao, X.1
Tong, L.2
-
65
-
-
0032557646
-
Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB
-
P.C. van Weeren, K.M. de Bruyn, A.M. de Vries-Smits, J. van Lint, and B.M. Burgering Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB J. Biol. Chem. 273 1998 13150 13156
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13150-13156
-
-
Van Weeren, P.C.1
De Bruyn, K.M.2
De Vries-Smits, A.M.3
Van Lint, J.4
Burgering, B.M.5
-
66
-
-
0027990353
-
A cell-autonomous, ubiquitous marker for the analysis of Drosophila genetic mosaics
-
J.P. Vincent, C.H. Girdham, and P.H. O'Farrell A cell-autonomous, ubiquitous marker for the analysis of Drosophila genetic mosaics Dev. Biol. 164 1994 328 331
-
(1994)
Dev. Biol.
, vol.164
, pp. 328-331
-
-
Vincent, J.P.1
Girdham, C.H.2
O'Farrell, P.H.3
-
67
-
-
0032552851
-
Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization
-
A. Wagenfeld, J. Gromoll, and T.G. Cooper Molecular cloning and expression of rat contraception associated protein 1 (CAP1), a protein putatively involved in fertilization Biochem. Biophys. Res. Commun. 251 1998 545 549
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.251
, pp. 545-549
-
-
Wagenfeld, A.1
Gromoll, J.2
Cooper, T.G.3
-
68
-
-
0033759452
-
Expression and cellular localization of contraception-associated protein
-
A. Wagenfeld, C.H. Yeung, S. Shivaji, V.R. Sundareswaran, H. Ariga, and T.G. Cooper Expression and cellular localization of contraception-associated protein J. Androl. 21 2000 954 963
-
(2000)
J. Androl.
, vol.21
, pp. 954-963
-
-
Wagenfeld, A.1
Yeung, C.H.2
Shivaji, S.3
Sundareswaran, V.R.4
Ariga, H.5
Cooper, T.G.6
-
69
-
-
0037168127
-
Novel candidate tumor marker genes for lung adenocarcinoma
-
K.K. Wang, N. Liu, N. Radulovich, D.A. Wigle, M.R. Johnston, F.A. Shepherd, M.D. Minden, and M.S. Tsao Novel candidate tumor marker genes for lung adenocarcinoma Oncogene 21 2002 7598 7604
-
(2002)
Oncogene
, vol.21
, pp. 7598-7604
-
-
Wang, K.K.1
Liu, N.2
Radulovich, N.3
Wigle, D.A.4
Johnston, M.R.5
Shepherd, F.A.6
Minden, M.D.7
Tsao, M.S.8
-
70
-
-
0042130551
-
The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease
-
M.A. Wilson, J.L. Collins, Y. Hod, D. Ringe, and G.A. Petsko The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease Proc. Natl. Acad. Sci. USA 100 2003 9256 9261
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 9256-9261
-
-
Wilson, M.A.1
Collins, J.L.2
Hod, Y.3
Ringe, D.4
Petsko, G.A.5
-
71
-
-
0242322051
-
Immunocytochemical localization of DJ-1 in human male reproductive tissue
-
K. Yoshida, Y. Sato, M. Yoshiike, S. Nozawa, H. Ariga, and T. Iwamoto Immunocytochemical localization of DJ-1 in human male reproductive tissue Mol. Reprod. Dev. 66 2003 391 397
-
(2003)
Mol. Reprod. Dev.
, vol.66
, pp. 391-397
-
-
Yoshida, K.1
Sato, Y.2
Yoshiike, M.3
Nozawa, S.4
Ariga, H.5
Iwamoto, T.6
-
72
-
-
12144288298
-
Skp2 gene copy number aberrations are common in non-small cell lung carcinoma, and its overexpression in tumors with ras mutation is a poor prognostic marker
-
C.Q. Zhu, F.H. Blackhall, M. Pintilie, P. Iyengar, N. Liu, J. Ho, T. Chomiak, D. Lau, T. Winton, F.A. Shepherd, and M.S. Tsao Skp2 gene copy number aberrations are common in non-small cell lung carcinoma, and its overexpression in tumors with ras mutation is a poor prognostic marker Clin. Cancer Res. 10 2004 1984 1991
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 1984-1991
-
-
Zhu, C.Q.1
Blackhall, F.H.2
Pintilie, M.3
Iyengar, P.4
Liu, N.5
Ho, J.6
Chomiak, T.7
Lau, D.8
Winton, T.9
Shepherd, F.A.10
Tsao, M.S.11
|