Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 22, 2005, Pages 8024-8029

  Whitworth, Alexander J ^a,d   Theodore, Dorothy A ^b   Greene, Jessica C ^a   Beneš, Helen ^c   Wes, Paul D ^b   Pallanck, Leo J ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b ELAN PHARMACEUTICALS   (United States)

^c UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Genetic modifier; Neurodegeneration; Parkin

Indexed keywords

GLUTATHIONE; GLUTATHIONE TRANSFERASE; PARKIN;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DROSOPHILA; ENZYME ACTIVITY; GENE FUNCTION; GENE LOSS; GENE MUTATION; GENE OVEREXPRESSION; GENETIC SCREENING; MUTANT; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PARKINSONISM; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; DROSOPHILA; DROSOPHILA PROTEINS; GENE EXPRESSION; GLUTATHIONE TRANSFERASE; GREEN FLUORESCENT PROTEINS; INTERNEURONS; LOCOMOTION; MICROSCOPY, CONFOCAL; MUTATION; NERVE DEGENERATION; PARKINSON DISEASE;

EID: 20344369560     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0501078102     Document Type: Article

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