메뉴 건너뛰기




Volumn 441, Issue 7097, 2006, Pages 1162-1166

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; ENZYMES; GENES; GENETIC ENGINEERING; PATHOLOGY;

EID: 33745589773     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04779     Document Type: Article
Times cited : (1502)

References (30)
  • 2
    • 2442668926 scopus 로고    scopus 로고
    • Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    • Valente, E. M. et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304, 1158-1160 (2004).
    • (2004) Science , vol.304 , pp. 1158-1160
    • Valente, E.M.1
  • 3
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada, T. et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608 (1998).
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1
  • 4
    • 22044432781 scopus 로고    scopus 로고
    • Early-onset parkinsonism associated with PINK1 mutations: Frequency, genotypes, and phenotypes
    • Bonifati, V. et al. Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. Neurology 65, 87-95 (2005).
    • (2005) Neurology , vol.65 , pp. 87-95
    • Bonifati, V.1
  • 5
    • 27244432742 scopus 로고    scopus 로고
    • PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism
    • Klein, C. et al. PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism. Eur. J. Hum. Genet. 13, 1086-1093 (2005).
    • (2005) Eur. J. Hum. Genet. , vol.13 , pp. 1086-1093
    • Klein, C.1
  • 6
    • 33244482539 scopus 로고    scopus 로고
    • Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa
    • Ibanez, P. et al. Mutational analysis of the PINK1 gene in early-onset parkinsonism in Europe and North Africa. Brain 129, 686-694 (2006).
    • (2006) Brain , vol.129 , pp. 686-694
    • Ibanez, P.1
  • 7
    • 0037386532 scopus 로고    scopus 로고
    • Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
    • Greene, J. C. et al. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc. Natl Acad. Sci. USA 100, 4078-4083 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 4078-4083
    • Greene, J.C.1
  • 8
    • 2542560342 scopus 로고    scopus 로고
    • Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
    • Pesah, Y. et al. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 131, 2183-2194 (2004).
    • (2004) Development , vol.131 , pp. 2183-2194
    • Pesah, Y.1
  • 9
    • 0003739085 scopus 로고
    • Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
    • Fuller, M. T. in The Development of Drosophila melanogaster 71-147 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1993).
    • (1993) The Development of Drosophila Melanogaster , pp. 71-147
    • Fuller, M.T.1
  • 10
    • 0023054140 scopus 로고
    • Targeting efficiency of a mitochondrial pre-sequence is dependent on the passenger protein
    • Van Steeg, H., Oudshoorn, P., Van Hell, B., Polman, J. E. & Grivell, L. A. Targeting efficiency of a mitochondrial pre-sequence is dependent on the passenger protein. EMBO J. 5, 3643-3650 (1986).
    • (1986) EMBO J. , vol.5 , pp. 3643-3650
    • Van Steeg, H.1    Oudshoorn, P.2    Van Hell, B.3    Polman, J.E.4    Grivell, L.A.5
  • 11
    • 27944444154 scopus 로고    scopus 로고
    • Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism. Hum
    • Silvestri, L. et al. Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism. Hum. Mol. Genet. 14, 3477-3492 (2005).
    • (2005) Mol. Genet. , vol.14 , pp. 3477-3492
    • Silvestri, L.1
  • 12
    • 24044472010 scopus 로고    scopus 로고
    • Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease
    • Meulener, M. et al. Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson's disease. Curr. Biol. 15, 1572-1577 (2005).
    • (2005) Curr. Biol. , vol.15 , pp. 1572-1577
    • Meulener, M.1
  • 13
    • 24044506249 scopus 로고    scopus 로고
    • Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress
    • Menzies, F. M., Yenisetti, S. C. & Min, K. T. Roles of Drosophila DJ-1 in survival of dopaminergic neurons and oxidative stress. Curr. Biol. 15, 1578-1582 (2005).
    • (2005) Curr. Biol. , vol.15 , pp. 1578-1582
    • Menzies, F.M.1    Yenisetti, S.C.2    Min, K.T.3
  • 14
    • 26444489693 scopus 로고    scopus 로고
    • Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling
    • Yang, Y. et al. Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl Acad. Sci. USA 102, 13670-13675 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 13670-13675
    • Yang, Y.1
  • 15
    • 27144519984 scopus 로고    scopus 로고
    • Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction
    • Park, J. et al. Drosophila DJ-1 mutants show oxidative stress-sensitive locomotive dysfunction. Gene 361, 133-139 (2005).
    • (2005) Gene , vol.361 , pp. 133-139
    • Park, J.1
  • 16
    • 0037428241 scopus 로고    scopus 로고
    • Mutations in the DJ-1 gene associated with autosoma recessive early-onset Parkinsonism
    • Bonifati, V. et al. Mutations in the DJ-1 gene associated with autosoma recessive early-onset Parkinsonism. Science 299, 256-259 (2003).
    • (2003) Science , vol.299 , pp. 256-259
    • Bonifati, V.1
  • 17
    • 17644413217 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen species: Weapons of neuronal destruction in models of Parkinson's disease
    • Przedborski, S. & Ischiropoulos, H. Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease. Antioxid. Redox Signal. 7, 685-693 (2005).
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 685-693
    • Przedborski, S.1    Ischiropoulos, H.2
  • 18
    • 19344368275 scopus 로고    scopus 로고
    • Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization
    • Huh, J. R. et al. Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization. PLoS Biol. 2, E15 (2004).
    • (2004) PLoS Biol. , vol.2
    • Huh, J.R.1
  • 19
    • 0027160708 scopus 로고
    • Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
    • Brand, A. H. & Perrimon, N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415 (1993).
    • (1993) Development , vol.118 , pp. 401-415
    • Brand, A.H.1    Perrimon, N.2
  • 20
    • 20344369560 scopus 로고    scopus 로고
    • Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease
    • Whitworth, A. J. et al. Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease. Proc. Natl Acad. Sci. USA 102, 8024-8029 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 8024-8029
    • Whitworth, A.J.1
  • 21
    • 26844527655 scopus 로고    scopus 로고
    • Genetic mouse models of parkinsonism: Strengths and limitations
    • Fleming, S. M., Fernagut, P. O. & Chesselet, M. F. Genetic mouse models of parkinsonism: strengths and limitations. NeuroRx 2, 495-503 (2005).
    • (2005) NeuroRx , vol.2 , pp. 495-503
    • Fleming, S.M.1    Fernagut, P.O.2    Chesselet, M.F.3
  • 22
    • 2442481789 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
    • Palacino, J. J. et al. Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. J. Biol. Chem. 279, 18614-18622 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 18614-18622
    • Palacino, J.J.1
  • 23
    • 0037333666 scopus 로고    scopus 로고
    • Staging of brain pathology related to sporadic Parkinson's disease
    • Braak, H. et al. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging 24, 197-211 (2003).
    • (2003) Neurobiol. Aging , vol.24 , pp. 197-211
    • Braak, H.1
  • 24
    • 0016772917 scopus 로고
    • Ultrastructure of skeletal muscle in patients with Parkinson's disease and upper motor lesions
    • Ahlqvist, G., Landin, S. & Wroblewski, R. Ultrastructure of skeletal muscle in patients with Parkinson's disease and upper motor lesions. Lab. Invest. 32, 673-679 (1975).
    • (1975) Lab. Invest. , vol.32 , pp. 673-679
    • Ahlqvist, G.1    Landin, S.2    Wroblewski, R.3
  • 26
    • 0033373674 scopus 로고    scopus 로고
    • Detection of respiratory chain defects in cultivated skin fibroblasts and skeletal muscle of patients with Parkinson's disease
    • Wiedemann, F. R., Winkler, K., Lins, H., Wallesch, C. W. & Kunz, W. S. Detection of respiratory chain defects in cultivated skin fibroblasts and skeletal muscle of patients with Parkinson's disease. Ann. NY Acad Sci. 893, 426-429 (1999).
    • (1999) Ann. NY Acad Sci. , vol.893 , pp. 426-429
    • Wiedemann, F.R.1    Winkler, K.2    Lins, H.3    Wallesch, C.W.4    Kunz, W.S.5
  • 27
    • 0028141705 scopus 로고
    • Expression of baculovirus P35 prevents cell death in Drosophila
    • Hay, B. A., Wolff, T. & Rubin, G. M. Expression of baculovirus P35 prevents cell death in Drosophila. Development 120, 2121-2129 (1994).
    • (1994) Development , vol.120 , pp. 2121-2129
    • Hay, B.A.1    Wolff, T.2    Rubin, G.M.3
  • 28
    • 0015254534 scopus 로고
    • Dynamics of spermiogenesis in Drosophila melanogaster. I. Individualization process
    • Tokuyasu, K. T., Peacock, W. J. & Hardy, R. W. Dynamics of spermiogenesis in Drosophila melanogaster. I. Individualization process. Z. Zellforsch. Mikrosk. Anat. 124, 479-506 (1972).
    • (1972) Z. Zellforsch. Mikrosk. Anat. , vol.124 , pp. 479-506
    • Tokuyasu, K.T.1    Peacock, W.J.2    Hardy, R.W.3
  • 29
    • 0015869913 scopus 로고
    • Genetic dissection of behaviour
    • Benzer, S. Genetic dissection of behaviour. Sci. Am. 229, 24-37 (1973).
    • (1973) Sci. Am. , vol.229 , pp. 24-37
    • Benzer, S.1
  • 30
    • 0029020282 scopus 로고
    • Protein kinases 6. The eukaryotic protein kinase superfamily: Kinase (catalytic) domain structure and classification
    • Hanks, S. K. & Hunter, T. Protein kinases 6. The eukaryotic protein kinase superfamily: kinase (catalytic) domain structure and classification. FASEB J. 9, 576-596 (1995).
    • (1995) FASEB J. , vol.9 , pp. 576-596
    • Hanks, S.K.1    Hunter, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.