Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice

Neuron

Volumn 24, Issue 4, 1999, Pages 879-892

  Cummings, Christopher J ^a   Reinstein, Eyal ^b   Yaling, Sun ^a   Antalffy, Barbara ^a   Jiang, Yong Hui ^a   Ciechanover, Aaron ^b   Orr, Harry T ^c   Beaudet, Arthur L ^a   Zoghbi, Huda Y ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

POLYGLUTAMINE; PROTEASOME; UBIQUITIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS INCLUSION BODY; ENZYME INDUCTION; GENE DELETION; GENE FREQUENCY; GENE MUTATION; GENETIC TRANSFECTION; MOUSE; NERVE DEGENERATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PURKINJE CELL; SPINOCEREBELLAR DEGENERATION; TISSUE DISTRIBUTION;

EID: 0033391428     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)81035-1     Document Type: Article

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